Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 13, 2026, 5:09 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 913–936 of 1,141 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Isotonic solution Clear all

Conditions: Pregnancy
Interventions: Iloprost, normal saline; Drug · Other
Lead sponsor: Fertility Specialists of Houston; Other
Eligibility: 20 Years to 39 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Healthy
Interventions: 5 mg/N6022, Placebo, 10mg/N6022, 20mg/N6022; Drug
Lead sponsor: Nivalis Therapeutics, Inc.; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Diabetes Mellitus, Type 1, Diabetic Ketoacidosis
Interventions: Glargine, IV insulin, Electrolyte Correction, Correction of Fluid Loss; Drug · Other
Lead sponsor: Chattanooga-Hamilton County Hospital Authority; Other
Eligibility: 1 Year to 21 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Chattanooga, Tennessee

Conditions: Osteoarthritis, Knee
Interventions: TissueGene-C, Normal Saline; Biological · Drug
Lead sponsor: Kolon TissueGene, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 5
States / cities: Pinellas Park, Florida • Baltimore, Maryland • Philadelphia, Pennsylvania + 2 more

Conditions: Marburg Hemorrhagic Fever
Interventions: AVI-7288, Placebo; Drug · Other
Lead sponsor: Sarepta Therapeutics, Inc.; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Pain
Interventions: Bupivacaine, Normal Saline; Drug · Other
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Abdominal Surgery
Interventions: Liposomal bupivacaine, Plain bupivacaine, Normal saline; Drug
Lead sponsor: Edward Mascha; Other
Eligibility: 18 Years to 85 Years
Enrollment: 285 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Acute Peripheral Arterial Occlusion
Interventions: Plasmin, Plasminogen Activator, Placebo; Biological · Other
Lead sponsor: Grifols Therapeutics LLC; Industry
Eligibility: 18 Years and older
Enrollment: 174 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 2
States / cities: Buffalo, New York • Cleveland, Ohio

Conditions: Radicular Low Back Pain
Interventions: Intramuscular methylprednisolone acetate, Placebo; Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 21 Years to 50 Years
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Chronic Kidney Disease
Interventions: GCS-100, Placebo, Saline; Drug
Lead sponsor: La Jolla Pharmaceutical Company; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 4
States / cities: Tempe, Arizona • La Mesa, California • Denver, Colorado + 1 more

Conditions: Type 2 Diabetes, Hypertension
Interventions: Rosiglitazone, Normal saline 0.9%, Intralipid 20%; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2009
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Pneumonia, Ventilator-Associated
Interventions: Aerosolized Tobramycin or Vancomycin, Aerosolized Placebo; Drug
Lead sponsor: Wright State University; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Dayton, Ohio

Conditions: Total Knee Arthroplasty
Interventions: Ropivacaine, Dexamethasone, Normal Saline; Drug
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Hip Fractures, Anesthesia, Spinal, Anesthesia, General, Neuromuscular Blockade
Interventions: Rocuronium, Sugammadex, Normal saline; Drug
Lead sponsor: Loyola University; Other
Eligibility: 55 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Respiratory Syncytial Virus Infections
Interventions: RSV Vaccine (GSK3844766A) unadjuvanted low dose, RSV Vaccine (GSK3844766A) low dose adjuvanted with AS01E, RSV Vaccine (GSK3844766A) low dose adjuvanted with AS01B, RSV Vaccine (GSK3844766A) unadjuvanted medium dose, RSV Vaccine (GSK3844766A) medium dose adjuvanted with AS01E, RSV Vaccine (GSK3844766A) medium dose adjuvanted with AS01B, RSV Vaccine (GSK3844766A) unadjuvanted high dose, RSV Vaccine (GSK3844766A) high dose adjuvanted with AS01E, RSV Vaccine (GSK3844766A) high dose adjuvanted with AS01B, Placebo (Saline solution); Biological · Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 1,053 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 18
States / cities: Jacksonville, Florida • Miami, Florida • Stockbridge, Georgia + 15 more

Conditions: Cleft Lip, Cleft Lip Scar
Interventions: Botulinum Toxin Type A (BOTOX) Injection, Normal Saline; Drug
Lead sponsor: Children's National Research Institute; Other
Eligibility: 0 Days to 12 Months
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2032
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Cardiac Surgical Procedures
Interventions: cyclosporine, saline solution; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 80 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Bone Metastases, Lymphoma, Multiple Myeloma, Opioid Use, Pain
Interventions: Ketorolac, Normal saline, Acetaminophen, Oxycodone Acetaminophen, Morphine, Hydrocodone/Acetaminophen, Oxycodone; Drug
Lead sponsor: St. Louis University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Pulmonary Arterial Hypertension (PAH)
Interventions: Tiprelestat (5 mg), Placebo (1 mL 0.9% saline solution), Tiprelestat (10 mg); Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 10
States / cities: Tucson, Arizona • San Francisco, California • Stanford, California + 7 more

Conditions: Spinal Cord Injury (=3 Years), Sublesional Bone Loss Secondary to SCI
Interventions: Romosozumab, Denosumab, Placebo; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: West Orange, New Jersey • The Bronx, New York

Conditions: Pain
Interventions: bupivacaine liposome injectable suspension, Placebo; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 156 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 17
States / cities: Mobile, Alabama • Englewood, Colorado • Miami, Florida + 12 more

Conditions: Lupus Nephritis
Interventions: Daxdilimab, Placebo (Normal Saline); Drug
Lead sponsor: Amgen; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 5
States / cities: Birmingham, Alabama • San Dimas, California • Syracuse, New York + 2 more

Conditions: ASCVD, Elevated Cholesterol
Interventions: Inclisiran Sodium, Placebo; Drug
Lead sponsor: The Medicines Company; Industry
Eligibility: 18 Years and older
Enrollment: 1,561 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 145
States / cities: Birmingham, Alabama • Foley, Alabama • Huntsville, Alabama + 110 more

Conditions: Osteoarthritis, Rheumatoid Nodule, Degenerative Joint Disease, Tendinopathy, Tendinosis, Back Pain
Interventions: Normal Saline, Tissue Stromal Vascular Fraction, Platelet Rich Plasma, Cellular Stromal Vascular Fraction; Drug · Procedure · Biological
Lead sponsor: Robert W Alexander, MD; Other
Eligibility: 18 Years to 90 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: North Attleboro, Massachusetts

Search by objective public record fields.

Enhanced Assisted Reproductive Technology Pregnancy Rate by Prostacyclin Analog (Iloprost)

A Safety Study Evaluating N6022 in Multiple-Ascending Doses in Healthy Subjects

Early Administration of Long-acting Insulin Treatment of Diabetic Ketoacidosis in Pediatric Type 1 Diabetes

Study of TG-C in Patients With Grade 3 Degenerative Joint Disease of the Knee

A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7288 in Healthy Adult Volunteers

Pain Relief at Iliac Crest Bone Harvest Sites in Spine Surgery Using Bupivacaine

Comparing TAP Blocks Bupivacaine, and Placebo for Plane

A Study of Intra-thrombus Plasmin (Human) In Acute Peripheral Arterial Occlusion

A Trial of Corticosteroids for Low Back Pain

A Phase 2a Study of Weekly Doses of GCS-100 in Patients With Chronic Kidney Disease

Free Fatty Acid-Induced Hypertension in Obese Subjects With Type 2 Diabetes

Aerosolized Antibiotics in the Treatment of Ventilator Associated Pneumonia

The Effects of Dexamethasone on the Duration of Sciatic Nerve Blocks

GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip Fracture

A Study to Assess the Safety, Reactogenicity and Immune Response of GlaxoSmithKline (GSK) Biologicals' Investigational Respiratory Syncytial Virus (RSV) Vaccine (GSK3844766A) in Older Adults

Cleft Lip Scarring After Botox

Trial of Cyclosporine for Myocardial Protection During Open Heart Surgery

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

Tiprelestat Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH)

Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI

Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block With EXPAREL in Shoulder Surgery

Study of Daxdilimab (HZN-7734) in Participants With Active Proliferative Lupus Nephritis (LN)

Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol

Cellular & Biocellular Regenerative Therapy in Musculoskeletal Pain, Dysfunction,Degenerative or Inflammatory Disease