Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 13, 2026, 8:29 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1009–1032 of 1,141 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Isotonic solution Clear all

Conditions: Chronic Sinusitis
Interventions: Xylitol, Saline; Drug
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years and older
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Encephalitis, Japanese Encephalitis
Interventions: ChimeriVax-JE, Japanese Encephalitis vaccine, 0.9% Saline; Biological
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years and older
Enrollment: 2,004 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2006
U.S. locations: 16
States / cities: Burbank, California • Costa Mesa, California • Davis, California + 13 more

Conditions: COVID-19
Interventions: RBT-9 (90 mg), 0.9% sodium chloride (normal saline); Drug
Lead sponsor: Renibus Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 5
States / cities: New Smyrna Beach, Florida • Berkley, Michigan • El Paso, Texas + 2 more

Conditions: Ocular Graft Versus Host Disease
Interventions: Amniotic Fluid Eye Drops (AFED), Saline Solution; Biological · Other
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: Hyperpolarized Helium-3, Placebo, Aformoterol; Drug
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 50 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Alopecia Areata
Interventions: CycloSPORINE Injectable Product, Saline Solution; Drug
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years to 65 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Septic Shock
Interventions: Hydrocortisone, sodium succinate, Normal saline; Drug
Lead sponsor: Jerry Zimmerman; Other
Eligibility: 1 Month to 17 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 18
States / cities: Tucson, Arizona • Los Angeles, California • Oakland, California + 15 more

Conditions: Non-Ischemic Heart Failure
Interventions: Allogeneic Mesenchymal Bone Marrow Cells (aMBMC), Lactated Ringer's Solution; Drug
Lead sponsor: CardioCell LLC; Industry
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 5
States / cities: Washington D.C., District of Columbia • Atlanta, Georgia • Chicago, Illinois + 2 more

Conditions: Diarrhea, Clostridium Difficile Infection
Interventions: 0.9% Normal Saline, Clostridium difficile toxoid vaccine, Clostridium difficile toxoid vaccine with adjuvant; Biological
Lead sponsor: Sanofi Pasteur, a Sanofi Company; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 5
States / cities: Tampa, Florida • Marietta, Georgia • Worcester, Massachusetts + 2 more

Conditions: Nausea, Vomiting
Interventions: Glycopyrrolate, Normal Saline; Drug
Lead sponsor: Kokila N Thenuwara; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Bronchiolitis
Interventions: Nebulized 3% saline, Nebulized 0.9% saline; Drug
Lead sponsor: Children's Hospital Los Angeles; Other
Eligibility: Up to 24 Months
Enrollment: 447 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 2
States / cities: Los Angeles, California • Oakland, California

Conditions: Obesity, Hypertension
Interventions: Angiotensin-(1-7), Saline; Drug
Lead sponsor: Amy Arnold; Other
Eligibility: 18 Years to 60 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Pain
Interventions: Infiltration of local anesthetic, Normal Saline Injection; Procedure
Lead sponsor: Trinity Health Of New England; Other
Eligibility: 18 Years to 80 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Glaucoma, Open-Angle
Interventions: Latanoprost 0.005%, Latanoprost bunod 0.024%, Normal saline 0.9%, Nailfold capillaroscopy; Drug · Diagnostic Test
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 40 Years to 80 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Major Depression
Interventions: Botox, Saline Solution; Drug
Lead sponsor: Capital Clinical Research Associates, LLC; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 2
States / cities: Chevy Chase, Maryland • Rockville, Maryland

Conditions: Obesity
Interventions: Ketamine, Ketamine plus magnesium, Placebo; Drug · Other
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Endometritis, Wound Infection, Abscess, Surgical Site Infection
Interventions: Azithromycin and standard of care, Placebo and standard of care; Drug
Lead sponsor: Alan Tita; Other
Eligibility: 14 Years and older · Female only
Enrollment: 2,013 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 9
States / cities: Birmingham, Alabama • New Orleans, Louisiana • Jackson, Mississippi + 6 more

Conditions: Cesarean Section, Pain, Postoperative
Interventions: IV Acetaminophen, Placebo; Drug
Lead sponsor: TriHealth Inc.; Other
Eligibility: 18 Years and older · Female only
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Traumatic Rib Fracture(s)
Interventions: Cryoneurolysis with a Painblocker (Epimed International, Farmers Branch, Texas), Intercostal nerve block ropivacaine with epinephrine, Sham cryoneurolysis with a Painblocker, Placebo intercostal nerve block with normal saline; Device · Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: San Diego, California

Conditions: Brain Injuries, Wounds and Injuries, Hemorrhage
Interventions: Tranexamic Acid, Placebo; Drug
Lead sponsor: Daniel Nishijima, MD, MAS; Other
Eligibility: Up to 17 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 4
States / cities: Sacramento, California • Columbus, Ohio • Philadelphia, Pennsylvania + 1 more

Conditions: Shock,Hemorrhagic
Interventions: Valproic Acid, Isotonic saline solution; Drug
Lead sponsor: Dr. Hasan Alam; Other
Eligibility: 18 Years to 65 Years
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Pain
Interventions: Lidocaine, Normal Saline, Propofol; Drug
Lead sponsor: Children's Hospitals and Clinics of Minnesota; Other
Eligibility: 2 Months to 17 Years
Enrollment: 171 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: Postural Tachycardia Syndrome
Interventions: Stellate ganglion block, Sham injection of saline, Ropivacaine, Normal saline; Procedure · Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Stanford, California

Conditions: Pain
Interventions: Caldolor, Normal Saline; Drug · Other
Lead sponsor: Cumberland Pharmaceuticals; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 185 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 6
States / cities: Mobile, Alabama • Little Rock, Arkansas • Arcadia, California + 2 more

Search by objective public record fields.

Xylitol Versus Saline in Chronic Sinusitis

Safety Study of ChimeriVax™-JE Vaccine to Prevent Japanese Encephalitis.

A Study to Evaluate the Effect of RBT-9 on Progression of COVID-19 in High-Risk Individuals (The PREVENT Study)

Study for the Treatment of Ocular Chronic Graft-Versus-Host Disease (GVHD) With Amniotic Fluid Eye Drops (AFED)

Assessment of Arformoterol for Chronic Obstructive Pulmonary Disease (COPD) Using Hyperpolarized 3He MRI

Intralesional Cyclosporine for Alopecia Areata

Stress Hydrocortisone In Pediatric Septic Shock

A Study to Assess the Effect of Intravenous Dose of (aMBMC) to Subjects With Non-ischemic Heart Failure

Study of a Clostridium Difficile Toxoid Vaccine (ACAM-CDIFF™) in Subjects With Clostridium Difficile Infection

Minimizing Nausea and Vomiting During Spinals for CS

Nebulized Hypertonic Saline for Bronchiolitis

Angiotensin 1-7 in Obesity Hypertension

Local Infiltration Analgesia for Hip Arthroscopy

Nailfold Capillary Blood Flow With Latanoprost Bunod

Efficacy Study of Botox for Depression

Effect of Single Dose Ketamine and Magnesium on Postoperative Pain in Patients Undergoing Bariatric Surgery

Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection

RCT (Randomized Controlled Trial) of IV Acetaminophen for Post Cesarean Pain Relief

Rib Fracture Analgesia Using Cryoanalgesia

Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: A Pilot and Feasibility Study

A Study to Evaluate the Safety and Tolerability of Valproic Acid in Healthy Volunteers (Part 1)

Decreasing Propofol Injection Pain by Pre-Treatment With Lidocaine in Pediatric Procedural Sedation

Ultrasound Guided Stellate Ganglion Block in Postural Tachycardia Syndrome

Efficacy and Safety Study of Caldolor (IV Ibuprofen) in Hospitalized Adult Orthopedic Patients