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ClinicalTrials.gov public records Last synced Sep 1, 2026, 11:58 PM EDT

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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Jawline Definition
Interventions
VOLUX XC, No-treatment control
Device · Other
Lead sponsor
Allergan
Industry
Eligibility
22 Years and older
Enrollment
206 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
19
States / cities
Birmingham, Alabama • Los Angeles, California • Santa Rosa, California + 14 more
Conditions
Temple Hollowing
Interventions
JUVÉDERM® VOLUMA® XC, No-treatment control
Device · Other
Lead sponsor
Allergan
Industry
Eligibility
22 Years and older
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
14
States / cities
Los Angeles, California • Newport Beach, California • Boca Raton, Florida + 11 more
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Saypha® VOLUME Lidocaine for Midface Augmentation

NCT05386030
Conditions
Moderate to Severe Midface Volume Deficit
Interventions
saypha® VOLUME Lidocaine, Juvéderm® Voluma™ XC
Combination Product
Lead sponsor
Croma-Pharma GmbH
Industry
Eligibility
22 Years to 75 Years
Enrollment
562 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
16
States / cities
Scottsdale, Arizona • Encino, California • Fremont, California + 13 more
Conditions
Chin Retrusion
Interventions
JUVÉDERM VOLUMA® XC
Device
Lead sponsor
Allergan
Industry
Eligibility
22 Years and older
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
14
States / cities
San Diego, California • Coral Gables, Florida • Miami Beach, Florida + 11 more
Completed Not applicable Interventional Results available

JUVÉDERM® VOLITE™ XC for Cheek Skin Smoothness

NCT03728309
Conditions
Skin Smoothness of the Cheeks
Interventions
JUVÉDERM VOLITE™ XC
Device
Lead sponsor
Allergan
Industry
Eligibility
22 Years and older
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
13
States / cities
Fresno, California • Los Angeles, California • Santa Monica, California + 10 more
Conditions
Skin Wrinkling
Interventions
Emervel Deep Lidocaine, Juvederm Ultra Plus
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
18 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
11
States / cities
Los Angeles, California • San Francisco, California • New Haven, Connecticut + 8 more
Conditions
Wrinkle
Interventions
Skinvive
Device
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
25 Years to 50 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Diego, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Jowl Improvement With Injectable Fillers

NCT04389866
Conditions
Jowls
Interventions
JUVÉDERM VOLUMA™ XC
Device
Lead sponsor
Advanced Dermatology
Other
Eligibility
35 Years to 75 Years · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Lincolnshire, Illinois
Conditions
Nasolabial Folds, Wrinkles
Interventions
TEOSYAL® RHA Global Action, TEOSYAL® RHA Deep Lines
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
5
States / cities
Birmingham, Alabama • Beverly Hills, California • Santa Monica, California + 2 more
Conditions
Intrinsic Aging of Skin
Interventions
Juvéderm Ultra, Cosmoderm 1
Device
Lead sponsor
Steven Fagien
Other
Eligibility
25 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Boca Raton, Florida
Conditions
Mid Face Volume Deficit
Interventions
JUVÉDERM VOLUX XC, JUVÉDERM VOLUMA XC, JUVÉDERM VOLBELLA XC, JUVÉDERM VOLLURE XC, SKINVIVE by JUVÉDERM, JUVÉDERM ULTRA XC, JUVÉDERM ULTRA PLUS XC
Device
Lead sponsor
AbbVie
Industry
Eligibility
22 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
10
States / cities
Los Angeles, California • San Diego, California • Vista, California + 7 more
Conditions
Temple Hollowing
Interventions
Juvéderm® VOLUMA XC
Device
Lead sponsor
Allergan
Industry
Eligibility
22 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Los Angeles, California
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Combination Facial Aesthetic Treatment in Millennials

NCT04755595
Conditions
Dermatological Non-Disease
Interventions
Botox Cosmetic Injectable Product, Juvéderm Voluma XC, Juvéderm Volbella XC
Drug · Device
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
24 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Brooklyn, New York
Conditions
Facial Contouring
Interventions
OnabotulinumtoxinA, JUVÉDERM, CoolSculpting Elite System, SkinMedica Products, KYBELLA
Drug · Device · Other
Lead sponsor
AbbVie
Industry
Eligibility
22 Years to 65 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
10
States / cities
Redondo Beach, California • Vista, California • Washington D.C., District of Columbia + 7 more
Conditions
Skin Wrinkling
Interventions
Emervel Classic Lidocaine, Juvederm® Ultra
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
18 Years and older
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
12
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 8 more
Conditions
Moderate to Severe Nasolabial Folds
Interventions
JUVEDERM VOLIFT® XC, Control
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
7
States / cities
Birmingham, Alabama • Los Angeles, California • San Francisco, California + 3 more
Conditions
Subjects Desiring Lip Augmentation
Interventions
JUVEDERM VOLBELLA® XC, Restylane-L®
Device
Lead sponsor
Allergan
Industry
Eligibility
22 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New Orleans, Louisiana
Completed Phase 4 Interventional Accepts healthy volunteers

A Prospective Evaluation of the Filler for Jaw Contouring

NCT06694857
Conditions
Dermal Fillers
Interventions
HA filler
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
22 Years to 55 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Infraorbital Hollowing
Interventions
JUVÉDERM VOLBELLA® XC injectable gel
Device
Lead sponsor
Allergan
Industry
Eligibility
22 Years and older
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
15
States / cities
Beverly Hills, California • Newport Beach, California • San Diego, California + 11 more
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Study of BOTOX and JUVEDERM for Treatment of Moderate to Severe Facial Wrinkles and Folds

NCT01269801
Conditions
Wrinkles
Interventions
onabotulinumtoxinA, JUVÉDERM
Drug
Lead sponsor
AboutSkin Dermatology and DermSurgery, PC
Industry
Eligibility
25 Years to 65 Years
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Englewood, Colorado
Conditions
Aging
Interventions
JUVÉDERM VOLUMA™ XC
Device
Lead sponsor
Baumann Cosmetic and Research Institute
Other
Eligibility
35 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Miami, Florida
Conditions
Neck Lines
Interventions
VOLITE XC
Device
Lead sponsor
AbbVie
Industry
Eligibility
22 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
15
States / cities
Newport Beach, California • Sacramento, California • San Diego, California + 11 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Juvéderm® VOLUMA XC Injectable Gel for Cheek Augmentation

NCT00978042
Conditions
Mid-facial Volume Deficit Related to Aging
Interventions
Juvéderm® VOLUMA XC
Device
Lead sponsor
Allergan
Industry
Eligibility
35 Years to 65 Years
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of JUVÉDERM™ Injectable Gel With Lidocaine

NCT00653861
Conditions
Nasolabial Folds
Interventions
JUVÉDERM™ Injectable Gel with Lidocaine, JUVÉDERM™ Injectable Gel
Device
Lead sponsor
Allergan Medical
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Mount Kisco, New York