- Conditions
- Nicotine Addiction, Cigarette Smoking
- Interventions
- Smoking research cigarettes with e-cigarette, Nicotine discrimination thresholds
- Drug
- Lead sponsor
- Rose Research Center, LLC
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 2
- States / cities
- Charlotte, North Carolina • Raleigh, North Carolina
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 30
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Smoking, Cigarette
- Interventions
- JUUL, Treatment As Usual
- Device · Other
- Lead sponsor
- Ohio State University Comprehensive Cancer Center
- Other
- Eligibility
- 21 Years to 99 Years
- Enrollment
- 350 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Nicotine Dependence, Electronic Cigarette Use, Cigarette Smoking
- Interventions
- Nicotine, Juul e-cigarette, Reduction
- Drug · Device · Behavioral
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 77 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Burlington, Vermont
- Conditions
- Nicotine Dependence
- Interventions
- Nicotine, JUUL e-cigarette
- Drug · Device
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 19 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Burlington, Vermont
- Conditions
- Electronic Cigarette Use, Tobacco Smoking
- Interventions
- JUUL ENDS, Combustible cigarette, comparator e-cigarette, Nicorette gum
- Other
- Lead sponsor
- Juul Labs, Inc.
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 137 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019
- U.S. locations
- 2
- States / cities
- Kansas City, Kansas • Lexington, Kentucky
- Conditions
- Tobacco Use
- Interventions
- Not listed
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Nicotine Administration & Dosage, E-cigarettes, Vaping, E-Liquid, Tobacco Smoking
- Interventions
- JUUL, Tobacco
- Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 2
- States / cities
- San Francisco, California
- Conditions
- Electronic Cigarettes
- Interventions
- JUUL electronic cigarette, IQOS electronic cigarette, Own Brand cigarette
- Other
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 21 Years to 55 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Cardiovascular Risk Factor, Nicotine Dependence
- Interventions
- Low Nicotine E-Liquid, Medium or High Nicotine E-Liquid
- Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 21 Years to 70 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 2
- States / cities
- San Francisco, California
- Conditions
- Healthy Volunteers
- Interventions
- Continue-smoking, myblu Tobacco 2.5%, myblu Tobacco 4.0%, myblu Honeymoon 2.5%, myblu Honeymoon 4.0%, JUUL 5%
- Other
- Lead sponsor
- Fontem Ventures BV
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 240 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Lincoln, Nebraska
- Conditions
- Smoking, Tobacco Use
- Interventions
- Pod System E-cig, Customizable Tank E-cig, Control
- Other
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Electronic Cigarette Use
- Interventions
- Electronic Cigarette containing nicotine, Electronic Cigarette without nicotine
- Device
- Lead sponsor
- Michigan Technological University
- Other
- Eligibility
- 21 Years to 40 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Houghton, Michigan
- Conditions
- Smoking Cessation, Harm Reduction, E-Cig Use, Cigarette Smoking, Tobacco Dependence, Tobacco Use Cessation
- Interventions
- JUUL
- Other
- Lead sponsor
- Rose Research Center, LLC
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 2
- States / cities
- Charlotte, North Carolina • Raleigh, North Carolina
- Conditions
- Cannabis, Nicotine
- Interventions
- Cannabis, Nicotine
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 26 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Head and Neck Squamous Cell Carcinoma, Lung Non-Small Cell Carcinoma, Stage I Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8, Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8, Stage IA2 Lung Cancer AJCC v8, Stage IA3 Lung Cancer AJCC v8, Stage IB Lung Cancer AJCC v8, Stage II Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
- Interventions
- Best Practice, Nicotine Replacement, Quality-of-Life Assessment, Questionnaire Administration
- Other · Drug
- Lead sponsor
- Ohio State University Comprehensive Cancer Center
- Other
- Eligibility
- 21 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Nicotine Dependence, Nicotine Dependence, Cigarettes, Tobacco Use, Tobacco Smoking
- Interventions
- Virginia Tobacco flavored JUUL 5% ENDS, Cool Mint flavored JUUL 5% ENDS, Mango flavored JUUL 5% ENDS, Creme Brulee flavored JUUL 5% ENDS, VUSE Solo e-cigarette, Nicorette White Ice Mint 4mg nicotine polacrilex gum, Usual Brand combustible cigarette
- Other
- Lead sponsor
- Juul Labs, Inc.
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 67 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Overland Park, Kansas
- Conditions
- Chronic Obstructive Pulmonary Disease, Chronic Bronchitis, Emphysema, Asthma-COPD Overlap Syndrome
- Interventions
- E-Cigarette, Financial Incentives
- Other · Behavioral
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Burlington, Vermont
- Conditions
- Electronic Cigarette Use
- Interventions
- 5% nicotine (Partial Nicotine Reduction), 3% or 2.4% nicotine (Partial Nicotine Reduction), 5% nicotine (Total Nicotine Reduction), 0% nicotine (Total Nicotine Reduction)
- Other
- Lead sponsor
- Florida International University
- Other
- Eligibility
- 21 Years to 35 Years
- Enrollment
- 116 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Tobacco Use
- Interventions
- Not listed
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 18 Years to 50 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Smoking Cessation
- Interventions
- Bupropion, Zonisamide, Placebo bupropion, Placebo zonisamide, E-cigarette
- Drug · Other
- Lead sponsor
- Rose Research Center, LLC
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 2
- States / cities
- Charlotte, North Carolina • Raleigh, North Carolina
- Conditions
- Electronic Cigarette Use, Cigarette Use, Electronic, Tobacco Use, Tobacco Smoking
- Interventions
- Switch from UB of Combustible Cigarette to JUUL 5% Virginia Tobacco ENDS, Switch from UB of Combustible Cigarette to JUUL 3% Virginia Tobacco ENDS, Switch from UB of Combustible Cigarette to JUUL 5% Mint ENDS, Switch from UB of Combustible Cigarette to JUUL 3% Mint ENDS, Switch from UB of Combustible Cigarette to JUUL 5% Menthol ENDS, Switch from UB of Combustible Cigarette to JUUL 3% Menthol ENDS, Switch from UB of Combustible Cigarette to JUUL 5% Mango ENDS, Switch from UB of Combustible Cigarette to JUUL 3% Mango ENDS, Switch to Dual-use of JUUL 5% and UB of Combustible Cigarette, Tobacco/Nicotine Abstention, Usual Brand of cigarettes
- Other
- Lead sponsor
- Juul Labs, Inc.
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 279 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 5
- States / cities
- Little Rock, Arkansas • Rogers, Arkansas • St Louis, Missouri + 2 more
- Conditions
- Schizophrenia and Related Disorders
- Interventions
- e-cigarette, brand name JUUL
- Device
- Lead sponsor
- Weill Medical College of Cornell University
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Vaping, E-cigarette Use, Electronic Cigarette Use
- Interventions
- Vape Messaging Intervention
- Behavioral
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 18 Years to 24 Years
- Enrollment
- 569 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Burlington, Vermont
- Conditions
- Tobacco Use, Nicotine Dependence, Other Tobacco Product, Tobacco Smoking
- Interventions
- JUUL 5%, Virginia Tobacco, ENDS product
- Other
- Lead sponsor
- Juul Labs, Inc.
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018
- U.S. locations
- 2
- States / cities
- Charlotte, North Carolina • Raleigh, North Carolina