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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:59 PM EDT

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Showing 1–24 of 273 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: KNOW Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Theta Burst Stimulation on the Brain, Behavior, and Clinical Symptoms in Adults With Bipolar Disorder

NCT04696471
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Continuous Theta Burst Stimulation (cTBS), Sham Continuous Theta Burst Stimulation (Sham cTBS)
Device
Lead sponsor
Mary Phillips, MD MD (Cantab)
Other
Eligibility
18 Years to 35 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 21, 2026, 6:59 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Let's Know!2: Language-focused Intervention for Children at Risk of Comprehension Difficulties

NCT05133479
View directory record Official record
Conditions
Language Disorders in Children
Interventions
Let's Know! small-group or TierL 2 Intervention
Behavioral
Lead sponsor
MGH Institute of Health Professions
Other
Eligibility
5 Years to 12 Years
Enrollment
241 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 21, 2026, 6:59 PM EDT
Terminated Phase 2 Interventional

Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI

NCT02148783
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
methylphenidate, Placebo
Drug
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 55 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 4, 2018 · Synced Oct 21, 2026, 6:59 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Inorganic Nitrate: Sex Differences in Muscle Contractile Function and Efficiency

NCT04588740
View directory record Official record
Conditions
Healthy
Interventions
concentrated beet root juice, Placebo beet root juice
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 34 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 21, 2026, 6:59 PM EDT
Completed Not applicable Interventional

Durham Housing Authority (DHA) Community Health Advisor (CHA) Smoking Cessation Project

NCT04114526
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine Replacement Therapy
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 12, 2020 · Synced Oct 21, 2026, 6:59 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1

NCT04481035
View directory record Official record
Conditions
Neurofibromatosis 1
Interventions
N-acetylcysteine (NAC), Placebo
Drug · Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
8 Years to 16 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 21, 2026, 6:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Different Methods of Patient Education on Preeclampsia

NCT02765906
View directory record Official record
Conditions
Preeclampsia, Anxiety, Hypertension, Pregnancy, Eclampsia, HELLP
Interventions
Graphic card, Video
Other
Lead sponsor
Geisinger Clinic
Other
Eligibility
Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Danville, Pennsylvania • Forty Fort, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Oct 21, 2026, 6:59 PM EDT
Completed Not applicable Interventional Results available

Serum Estradiol Levels In Postmenopausal Women With Breast Cancer Receiving Adjuvant Aromatase Inhibitors and Vaginal Estrogen

NCT00984399
View directory record Official record
Conditions
Atrophic Vaginitis, Breast Cancer
Interventions
Vagifem® (vaginal 17β-estradiol) questionnaire & menopause symptom checklist
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2024
U.S. locations
5
States / cities
Basking Ridge, New Jersey • Commack, New York • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Oct 21, 2026, 6:59 PM EDT
Completed Not applicable Interventional Results available

Does Memantine Improve Verbal Memory Task Performance in Subjects With Partial Epilepsy and Memory Dysfunction?

NCT01054599
View directory record Official record
Conditions
Epilepsy
Interventions
Memantine, Sugar Pill
Drug · Other
Lead sponsor
American Academy of Neurology
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
3
States / cities
Atlanta, Georgia • Boston, Massachusetts • Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 21, 2026, 6:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Graphic Messages to Prevent E-Cigarette Use Among Black and Latino Adolescents

NCT04899999
View directory record Official record
Conditions
Vaping
Interventions
Financial reward graphic message, Health reward graphic message, Self-efficacy graphic message, Social norms graphic message
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
12 Years to 17 Years
Enrollment
362 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 1, 2025 · Synced Oct 21, 2026, 6:59 PM EDT
Terminated Not applicable Interventional

Rigorous Evaluation of Yes and Know, a Fully Virtual Sexual Health and Well-Being Intervention for Youth

NCT06581536
View directory record Official record
Conditions
Pregnancy Related, Sexually Transmitted Diseases, Adolescent Behavior
Interventions
Yes and Know curriculum, Nutrition Education for Adolescents
Behavioral
Lead sponsor
ETR Associates
Other
Eligibility
14 Years to 19 Years
Enrollment
449 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Watsonville, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 21, 2026, 6:59 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Medicinal vs. Orthotic Comparison for Migraine Prevention: A Double-Blind Study

NCT04547179
View directory record Official record
Conditions
Migraine
Interventions
Fremanezumab-Vfrm, BLAfit®, Saline
Drug · Device · Other
Lead sponsor
Manhattan Beach Orthodontics
Other
Eligibility
18 Years to 55 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Manhattan Beach, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2021 · Synced Oct 21, 2026, 6:59 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Capturing Autobiographical Memory Formation in Real World Spaces Using Multimodal Recordings

NCT06883981
View directory record Official record
Conditions
Epilepsy, Autobiographical Memory
Interventions
Free and Cued Recall Memory. Temporal Sequence and Spatial Memory
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 21, 2026, 6:59 PM EDT
Enrolling by invitation Not applicable Interventional

Temporally Interfering Electric Field Stimulation in the Treatment of Epilepsy

NCT06716866
View directory record Official record
Conditions
Epilepsy
Interventions
temporally-interfering electric field stimulation
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
2
States / cities
Sacramento, California • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 21, 2026, 6:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Randomized Controlled Trial to Improve Teen Driving

NCT01624597
View directory record Official record
Conditions
Motor Vehicle Driving
Interventions
In-vehicle video feedback, Parent communication
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
14 Years to 17 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
2
States / cities
Des Moines, Iowa • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 21, 2026, 6:59 PM EDT
Completed Phase 4 Interventional Results available

Effects of SGLT-2 Inhibition on Myocardial Fibrosis and Inflammation as Assessed by Cardiac MRI in Patients With DM2

NCT03782259
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Myocardial Fibrosis, Myocardial Inflammation
Interventions
dapagliflozin, Placebo
Drug · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 29, 2023 · Synced Oct 21, 2026, 6:59 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Use of the Electronic Medical Record to Screen Code Status Preference Using Death Language

NCT07405710
View directory record Official record
Conditions
Code Status Discussions With Medical In-patients
Interventions
Death language
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
65 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 21, 2026, 6:59 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Gene Transfer Clinical Trial for Duchenne Muscular Dystrophy Using rAAVrh74.MCK.GALGT2

NCT02704325
View directory record Official record
Conditions
Duchenne Muscular Dystrophy
Interventions
rAAVrh74.MCK.GALGT2, PLACEBO (Saline)
Biological · Other
Lead sponsor
Kevin Flanigan
Other
Eligibility
9 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 6, 2018 · Synced Oct 21, 2026, 6:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

One-step HCV RNA Testing Among SSP Participants (HOT Study)

NCT06634342
View directory record Official record
Conditions
Testing Effect of Intervention
Interventions
HCV RNA Rapid testing
Diagnostic Test
Lead sponsor
University of Washington
Other
Eligibility
22 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 21, 2026, 6:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Personal Responsibility Education Program Innovative Strategies: Digital Initiative for Youth

NCT03765255
View directory record Official record
Conditions
Reproductive Health, Contraception, Sexually Transmitted Diseases
Interventions
In the Know: sexual health education
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 19 Years
Enrollment
1,260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Oct 21, 2026, 6:59 PM EDT
Not listed Not applicable Interventional

Testing Mediators and Moderators of a Fotonovela for Depression to Promote Help-seeking Behavior

NCT04319458
View directory record Official record
Conditions
Mental Health Literacy
Interventions
Fotonovela, Control
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 21, 2026, 6:59 PM EDT
Completed Not applicable Interventional

Vascular Malformations and Abnormalities of Growth

NCT01105676
View directory record Official record
Conditions
Abnormality
Interventions
skin biopsy
Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
12 Months and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 7, 2014 · Synced Oct 21, 2026, 6:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Developing a Communication Intervention for People With Memory Challenges and Their Care Partners

NCT05143255
View directory record Official record
Conditions
Alzheimer Disease, Dementia
Interventions
KNOW
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 21, 2026, 6:59 PM EDT
Terminated Not applicable Interventional Results available

Efficacy of Continuous Glucose Monitoring in Neonates With Hypoglycemia

NCT02300285
View directory record Official record
Conditions
Hypoglycemia, Newborn Morbidity
Interventions
Continuous Glucose Monitoring
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 60 Days
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Oct 21, 2026, 6:59 PM EDT