Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 8:54 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Knee Aspiration Clear all

Conditions: Bilateral Primary Osteoarthritis of Knee
Interventions: Autologous Bone Marrow Aspirate Concentrate, Sterile saline; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 99 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Arthroplasty, Replacement, Knee, Pain, Postoperative
Interventions: Adductor Canal Block, Adductor Canal Block; Procedure · Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Cartilage Injury
Interventions: Autologous bone marrow aspirate will be harvested and concentrated to a bone marrow aspirate concentrate (BMAC) containing bone marrow derived mesenchymal stem cells and delivered to site of operation, Control group incision; Procedure
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 50 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Knee Osteoarthritis
Interventions: Arthrex Angel System used to prepare injection of Bone Marrow Concentrate (BMC), Saline injection; Device · Other
Lead sponsor: University of Delaware; Other
Eligibility: 40 Years to 79 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Arthroplasty, Replacement, Knee, Nerve Block
Interventions: Adductor Canal Block, Bupivacaine, Femoral Nerve Block, Bupivacaine; Procedure
Lead sponsor: George Macrinici; Other
Eligibility: 40 Years to 80 Years
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Joliet, Illinois

Conditions: Osteoarthritis, Knee
Interventions: BMA Injection, BMA; Procedure · Biological
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 79 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture
Interventions: Experimental Group, Control Group; Drug · Other
Lead sponsor: Andrews Research & Education Foundation; Other
Eligibility: 14 Years to 40 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Gulf Breeze, Florida

Conditions: Osteochondral Defect, Articular Cartilage Defect
Interventions: Biologically Augmented Osteochondral Allograft Transplantation; Procedure
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Osteoarthritis, Knee, Microfragmented Adipose Tissue, Platelet-Rich Plasma
Interventions: Platelet Rich Plasma; Device
Lead sponsor: Ohio State University; Other
Eligibility: 25 Years to 75 Years
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Knee Osteoarthritis
Interventions: Physical Therapy, Platelet-Rich Plasma Injection, Photobiomodulation Therapy; Other · Biological · Device
Lead sponsor: Musculoskeletal Injury Rehabilitation Research for Operational Readiness; Federal
Eligibility: 18 Years to 64 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Knee Osteoarthritis
Interventions: Laser Cell Therapy; Procedure
Lead sponsor: Endocellutions; Industry
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Steubenville, Ohio

Conditions: Tibial Fractures
Interventions: Aspiration, Bupivacaine; Procedure · Drug
Lead sponsor: Loyola University; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Osteo Arthritis Knee
Interventions: Bone Marrow Aspirate Concentrate, Angel Concentrated Platelet Rich Plasma (cPRP) System; Biological · Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 45 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Osteoarthritis, Knee
Interventions: BMA cell therapy injection; Procedure
Lead sponsor: Advanced Orthopaedic Specialists; Other
Eligibility: 18 Years to 79 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Fayetteville, Arkansas

Conditions: Osteoarthritis, Knee
Interventions: Autologous adipose tissue injection, Hyaluronic Acid; Biological · Drug
Lead sponsor: University of Southern California; Other
Eligibility: 45 Years to 75 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Acute Postoperative Pain, Surgery
Interventions: continuous peripheral nerve block with OnQ pump, single injection nerve block; Device · Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Arthritis
Interventions: Blood samples, Synovial fluid aspiration, Synovial tissue sample; Other
Lead sponsor: MedImmune LLC; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 3
States / cities: Frederick, Maryland • Wyomissing, Pennsylvania • Jackson, Tennessee

Conditions: Anterior Cruciate Ligament (ACL) Tear
Interventions: Knee Aspiration; Procedure
Lead sponsor: Ohio State University; Other
Eligibility: 15 Years to 40 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: Columbus, Ohio • Dublin, Ohio

Conditions: Osteoarthritis
Interventions: Bone Marrow Derived MSCs, Adipose-derived MSCs, Umbilical Cord Tissue (UCT) MSCs, Corticosteroid injection; Biological · Drug
Lead sponsor: Emory University; Other
Eligibility: 40 Years to 70 Years
Enrollment: 475 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 5
States / cities: Gulf Breeze, Florida • Atlanta, Georgia • Durham, North Carolina + 2 more

Search by objective public record fields.

Use of Autologous Bone Marrow Aspirate Concentrate in Painful Knee Osteoarthritis

Adductor Canal Block for Total Knee Arthroplasty

Autologous Bone Marrow Concentrate in Knee Osteochondral Allograft Transplantation

Knee Injections for the Clinical Management of Knee OsteoArthritis

Study to Evaluate ACB Versus FNB Early Postoperative Period Functional Outcomes After TKA

Intra-articular Autologous Bone Marrow Aspirate Injection for Knee Osteoarthritis

Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears

Biologic Augmentation of Osteochondral Allograft Transplantation in the Knee

Microfragmented Adipose Tissue Versus Platelet-rich Plasma for Knee Osteoarthritis: a Randomized Comparative Trial

Investigating Orthobiologics After PRP and Photobiomodulation for Knee Osteoarthritis

Laser Cell Therapy for Knee Cartilage Repair

Intra-articular Local Anesthetic Injection and Hematoma Aspiration

Bone Marrow Aspirate Concentrate (BMAC)Treatment for Knee Osteoarthritis

Open Ended Trocar vs. Fenestrated Blunt Trocar in Bone Marrow Aspirate for Osteoarthritis

Intra-articular Adipose Tissue Injections for Osteoarthritis

Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty

A Study to Evaluate BioMarkers in Blood Samples in Subjects With Rheumatoid Arthritis

Arthrocentesis vs Observation Study for Acute ACL Tears

Multicenter Trial of Stem Cell Therapy for Osteoarthritis (MILES)