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ClinicalTrials.gov public records Last synced Sep 28, 2026, 10:27 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Knee Brace Clear all
Recruiting Not applicable Interventional

Nomad P-KAFO Study

NCT05644522
View directory record Official record
Conditions
Cerebrovascular Accident, Post-polio Syndrome, Spinal Cord Injuries, Multiple Sclerosis, Muscular Dystrophy, Paralysis
Interventions
Indego Nomad® Powered Knee-Ankle-Foot Orthosis (P-KAFO) (Parker Hannifin Corp., Cleveland, OH)
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 89 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 28, 2026, 10:27 AM EDT
Terminated Not applicable Interventional

Knee Split Comparison After ACL Reconstruction

NCT04360928
View directory record Official record
Conditions
ACL Tear, Arthrofibrosis, ACL Injury
Interventions
Graymont X ERIS Knee Splint, Standard Hinge Knee Brace
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Sep 28, 2026, 10:27 AM EDT
Completed Not applicable Interventional

Effects of Spinal Stabilization Exercises on Dynamic Balance and Functional Performance in Adults With Low Back Pain

NCT03597191
View directory record Official record
Conditions
Low Back Pain, Chronic Low Back Pain, Subacute Low Back Pain
Interventions
Exercises
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 1, 2019 · Synced Sep 28, 2026, 10:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

NCT06127264
View directory record Official record
Conditions
Healthy, Ankle Foot Orthosis (AFO), Peripheral Neuropathy
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Sep 28, 2026, 10:27 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Prospective Trial of the TriFit™ Web Knee Brace

NCT03633071
View directory record Official record
Conditions
Satisfaction
Interventions
Web-knee brace
Other
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
21 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Sep 28, 2026, 10:27 AM EDT
Not yet recruiting Not applicable Interventional

The Effect of a Novel Joint Distraction Knee Orthosis for Treating Medial Knee Osteoarthritis

NCT07439315
View directory record Official record
Conditions
Medial Compartment Knee Osteoarthritis
Interventions
Medial joint distraction brace
Device
Lead sponsor
Icarus Medical Innovations
Industry
Eligibility
30 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 28, 2026, 10:27 AM EDT
Completed Not applicable Interventional Results available

Intra Articular Injections With Platelet Rich Plasma in Patients With Juvenile Osteochondritis Dissecans of the Knee

NCT02397278
View directory record Official record
Conditions
Osteochondritis Dissecans
Interventions
Platelet rich plasma (PRP)
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 17 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Sep 28, 2026, 10:27 AM EDT
Completed Phase 4 Interventional Results available

Mobility Training Using a Bionic Knee Orthosis in Patients Chronic Post-Stroke: A Case Series

NCT01499862
View directory record Official record
Conditions
Stroke
Interventions
Tibion Bionic Leg
Device
Lead sponsor
Tibion Bionics, Inc.
Industry
Eligibility
40 Years to 60 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2013 · Synced Sep 28, 2026, 10:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Protonics Knee Brace Versus Hamstring Resisted Exercise (HRE) on Individuals With Patellofemoral Pain Syndrome

NCT03042559
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Protonics Knee brace, Sports Cords
Device
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 45 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated May 14, 2020 · Synced Sep 28, 2026, 10:27 AM EDT
Withdrawn Not applicable Interventional

Internal Bracing Following ACL Reconstruction

NCT06289153
View directory record Official record
Conditions
ACL Injury
Interventions
Arthrex Internal Brace, ACL Reconstruction
Device · Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Sep 28, 2026, 10:27 AM EDT
Completed Not applicable Interventional Results available

Ankle Foot Orthosis Comparative Effect

NCT03901053
View directory record Official record
Conditions
Foot Injuries and Disorders
Interventions
Reaktiv AFO, PhatBrace AFO
Device
Lead sponsor
Jason Wilken
Other
Eligibility
18 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
Iowa City, Iowa • Bethesda, Maryland • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 28, 2026, 10:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effects of Footplate Stiffness on Foot Loading Within Carbon Fiber Custom Dynamic Orthoses

NCT07312032
View directory record Official record
Conditions
Trauma Injury
Interventions
Carbon Fiber Custom Dynamic Orthosis, Carbon Fiber Footplate
Device
Lead sponsor
Jason Wilken
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Sep 28, 2026, 10:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Unloader Bracing in Clinical Outcome and Cartilage Physiology Following Microfracture of Chondral Defects

NCT02016300
View directory record Official record
Conditions
Cartilage Loss, Microfracture
Interventions
Unloader Bracing, Non-Bracing
Device
Lead sponsor
Stanford University
Other
Eligibility
15 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2019 · Synced Sep 28, 2026, 10:27 AM EDT
Recruiting No phase listed Observational

C-Brace Prospective Registry

NCT04640584
View directory record Official record
Conditions
Pareses, Lower Extremity
Interventions
C-Brace
Device
Lead sponsor
Otto Bock Healthcare Products GmbH
Industry
Eligibility
Not listed
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
70
States / cities
Harrison, Arkansas • Rogers, Arkansas • San Diego, California + 63 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 28, 2026, 10:27 AM EDT
Active, not recruiting Not applicable Interventional

C-Brace II Spinal Cord Injury

NCT03930056
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
C-Brace II, Traditional Care KAFO intervention
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 28, 2026, 10:27 AM EDT
Completed Not applicable Interventional Results available

Trial of Realignment Therapy for Treatment of Medial Knee Osteoarthritis

NCT00124462
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Realigning knee brace and custom orthodic, Non realigning knee brace and flat orthodic
Device
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Sep 28, 2026, 10:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Analysis of Human Movement With Assistive Devices

NCT05729061
View directory record Official record
Conditions
Limb Loss, Limb Weakness, Limb Paralysis, Movement Disorders
Interventions
Assist-Knee, Prosthetic Knee, Prosthetic Ankle, Prosthetic Foot, Ankle-Foot Orthosis
Device
Lead sponsor
Orthocare Innovations, LLC
Industry
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Edmonds, Washington
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Sep 28, 2026, 10:27 AM EDT
Recruiting Not applicable Interventional

Total Contact Soft Cast in Diabetic Foot Ulcers

NCT04210089
View directory record Official record
Conditions
Diabetic Foot Ulcer, Diabetes Mellitus, Foot Ulcer, Foot Ulcer, Diabetic, Ulcer, Ulcer Foot, Ulcer, Leg, Ankle Ulcer
Interventions
Total Contact Soft Cast, Cam Boot
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 28, 2026, 10:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Wedged Orthoses and Knee Osteoarthritis

NCT00420147
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
wedged inshoe orthosis, neutral inshoe orthosis
Device
Lead sponsor
University of Delaware
Other
Eligibility
40 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 15, 2017 · Synced Sep 28, 2026, 10:27 AM EDT
Completed Not applicable Interventional Results available

Knee Bracing for People With Patellofemoral Osteoarthritis

NCT00381563
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Patellofemoral realigning knee brace, Non-aligning knee brace
Device
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Sep 28, 2026, 10:27 AM EDT
Recruiting Not applicable Interventional

A Comparison Of Primary TKA Rehabilitation Using A Smart Orthotic Versus Outpatient Physical Therapy

NCT04924205
View directory record Official record
Conditions
Arthropathy of Knee
Interventions
FM2 Knee Brace
Device
Lead sponsor
Nicolas Noiseux, MD, MS, FRCSC
Other
Eligibility
18 Years to 100 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 28, 2026, 10:27 AM EDT
Withdrawn Not applicable Interventional

Dynamic ACL Brace: In Vivo Kinematics

NCT03670550
View directory record Official record
Conditions
ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL, ACL - Anterior Cruciate Ligament Deficiency
Interventions
Ossur Rebound ACL Brace
Device
Lead sponsor
Steadman Philippon Research Institute
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Vail, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 28, 2026, 10:27 AM EDT
Completed Not applicable Interventional

Effect of Knee Bracing on Improving Pain & Disability

NCT04044612
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Medial Unloader Brace
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
40 Years to 75 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 7, 2021 · Synced Sep 28, 2026, 10:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Heel Wedges and Carbon Fiber Custom Dynamic Orthoses to Control Knee Biomechanics

NCT05209360
View directory record Official record
Conditions
Adult ALL, Healthy
Interventions
Medial or Lateral Wedge, Carbon Fiber Custom Dynamic Orthosis
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced Sep 28, 2026, 10:27 AM EDT