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Showing 1–24 of 82 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Knee MRI Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn Disease

NCT04508088
View directory record Official record
Conditions
Inflammatory Bowel Disease, Crohn Disease
Interventions
Coronal T1 weighted spin echo images, Spin-lattice relaxation (T1), Magnetic resonance spectroscopy, Blood Draw
Diagnostic Test
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
13 Years to 20 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Sep 6, 2026, 2:22 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Cooled RF Lesion MRI Characteristics

NCT03631030
View directory record Official record
Conditions
Arthritis;Lumbosacral, Osteo Arthritis Knee, Sacroiliitis, Hip Osteoarthritis, Arthritis, Degenerative
Interventions
Cooled radiofrequency ablation
Device
Lead sponsor
International Spine, Pain and Performance Center
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 6, 2019 · Synced Sep 6, 2026, 2:22 AM EDT
Terminated Phase 4 Interventional

Knee Articular Cartilage Debridement in Conjunction With Partial Meniscectomy

NCT00613535
View directory record Official record
Conditions
Torn Meniscus
Interventions
Mechanical Debridement, Paragon T2, Lavage debridement, RF- based Debridement
Device · Procedure
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
10
States / cities
Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 6 more
Source: ClinicalTrials.gov public record
Updated May 18, 2015 · Synced Sep 6, 2026, 2:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

NEPAL (Neuromodulatory Examination of Pain and Mobility Across the Lifespan)

NCT02488863
View directory record Official record
Conditions
Musculoskeletal Pain, Pain, Chronic
Interventions
MRI Neuroimaging, Quantitative Sensory Testing, Questionnaires, Physical and Cognitive Function Testing
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
4
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Sep 6, 2026, 2:22 AM EDT
Terminated No phase listed Observational

The Diagnostic Accuracy of the Clinical Examination

NCT03850470
View directory record Official record
Conditions
Musculoskeletal Pain, Musculoskeletal Injury
Interventions
clinical examination, MRI
Diagnostic Test · Other
Lead sponsor
High Point University
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 26, 2021 · Synced Sep 6, 2026, 2:22 AM EDT
Completed Not applicable Interventional

A Randomized Prospective Trial of Total Knee Arthroplasty Options Comparing Standard Knee Cutting Guides and MRI Generated Patient Specific Custom Cutting Guides

NCT01072019
View directory record Official record
Conditions
Osteoarthritis of the Knee
Interventions
Instrument
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 26, 2018 · Synced Sep 6, 2026, 2:22 AM EDT
Completed No phase listed Observational

Intra-articular Volumetric Assessment After Total Knee Arthroplasty

NCT02821325
View directory record Official record
Conditions
Hematoma
Interventions
MRI
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 89 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 25, 2018 · Synced Sep 6, 2026, 2:22 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

MOON Onsite MRI 10 Years After ACL Reconstruction

NCT04660955
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
No Intervention - Observational study with MRI
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
22 Years to 45 Years
Enrollment
219 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 6, 2026, 2:22 AM EDT
Completed Not applicable Interventional

Clinical Efficacy Study Comparing VisionScope Imaging (VSI) to Magnetic Resonance Imaging (MRI) in Injuries of the Knee

NCT01695720
View directory record Official record
Conditions
Meniscus Tears, Loose Bodies, Articular Osteoarthritis, Articular or Capsular Trauma
Interventions
VisionScope Imaging (VSI) Exam
Procedure
Lead sponsor
VisionScope Technologies
Industry
Eligibility
18 Years to 75 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
7
States / cities
Los Angeles, California • Redwood City, California • Santa Monica, California + 4 more
Source: ClinicalTrials.gov public record
Updated May 30, 2013 · Synced Sep 6, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pain in Fibrous Dysplasia

NCT04125862
View directory record Official record
Conditions
Fibrous Dysplasia/McCune-Albright Syndrome
Interventions
MRI-based Neuroimaging, Non-contrast MRI, 18F-FDG-PET/CT, 18F-NaF-PET/CT
Diagnostic Test
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 45 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 6, 2026, 2:22 AM EDT
Completed Phase 2Phase 3 Interventional

A Placebo-Controlled Study of Collagen Hydrolysate in Subjects With Knee Osteoarthritis (OA)

NCT00536302
View directory record Official record
Conditions
Knee Osteoarthritis (OA)
Interventions
Collagen Hydrolysate, Placebo
Dietary Supplement
Lead sponsor
GELITA
Industry
Eligibility
49 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 5, 2009 · Synced Sep 6, 2026, 2:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

MR Imaging of Knee Osteoarthritis and Acute Knee Injuries

NCT00504114
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
ACL Reconstruction Surgery, Cartilage Resurfacing Surgery, Total Knee Replacement
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 11, 2013 · Synced Sep 6, 2026, 2:22 AM EDT
Terminated Phase 2 Interventional Results available

A Safety and Efficacy Study of Anti-inflammatory (Canakinumab) and Cartilage Stimulating (LNA043) Drugs Injected Into the Knee Joint of Participants With Knee Osteoarthritis (OA)

NCT04814368
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
canakinumab, LNA043, Placebo to canakinumab
Biological · Other
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
40 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
5
States / cities
La Mesa, California • Clearwater, Florida • Sunrise, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Sep 6, 2026, 2:22 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Chromosome 18 Clinical Research Center

NCT00227253
View directory record Official record
Conditions
Chromosome Aberrations, Growth Hormone Deficiency, Hypomyelination
Interventions
Determination of growth hormone status, Measurement of growth, thyroid and sex hormone levels, Behavior and neuropsychometric evaluations, Audiological and ear, nose and throat examination, Magnetic resonance imaging of the brain, Dysmorphology evaluation, Neurology examination, Dental evaluation, Speech pathology evaluation, Psychiatric evaluation, Orthopedic evaluation, Ophthalmologic evaluation, Gastrointestinal evaluation
Procedure
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
Not listed
Enrollment
4,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1993 – 2040
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Sep 6, 2026, 2:22 AM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers

64Cu-LLP2A for Imaging Multiple Myeloma

NCT03804424
View directory record Official record
Conditions
Multiple Myeloma
Interventions
64Cu-LLP2A, PET/MR, Blood samples for serum stability, Blood samples for metabolite analysis, Urine sample, Tumor biopsy, Electrocardiogram, PET/CT
Drug · Device · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 6, 2026, 2:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Feasibility Trial Using Imaging and Biochemical Technologies to Measure Knee Cartilage Composition in Acute ACL Injury

NCT02010125
View directory record Official record
Conditions
Acute Injury of Anterior Cruciate Ligament
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 70 Years
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2018 · Synced Sep 6, 2026, 2:22 AM EDT
Completed Not applicable Interventional

Loaded and Unloaded Magnetic Resonance (MR) Imaging of Meniscus-Cartilage-Trabecular Bone in Osteoarthritis

NCT01919736
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Gait Retraining
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
35 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 17, 2019 · Synced Sep 6, 2026, 2:22 AM EDT
Not listed No phase listed Observational

Andrews Return to Sport ACL Score

NCT05578248
View directory record Official record
Conditions
ACL Injury
Interventions
Magnetic Resonance Imaging (MRI), ACL reconstruction
Diagnostic Test · Procedure
Lead sponsor
Andrews Research & Education Foundation
Other
Eligibility
14 Years to 24 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Gulf Breeze, Florida
Source: ClinicalTrials.gov public record
Updated Oct 12, 2022 · Synced Sep 6, 2026, 2:22 AM EDT
Terminated Not applicable Interventional Results available

Mechanical vs. Radiofrequency-Based Debridement in the Treatment of Articular Cartilage Lesions

NCT01803880
View directory record Official record
Conditions
Chondral Lesion Plus Partial Medial Meniscectomy
Interventions
Mechanical Debridement, RF-Based Debridement
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
7
States / cities
Tucson, Arizona • Gulf Breeze, Florida • Greenwood, Indiana + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2019 · Synced Sep 6, 2026, 2:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty

NCT04166539
View directory record Official record
Conditions
Metallosis, Pain, Total Hip Replacement, Total Knee Replacement
Interventions
Questionnaires, Interviews, Blood draw, Magnetic Resonance Imaging, Echocardiogram
Behavioral · Other · Radiation + 1 more
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Sep 6, 2026, 2:22 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis

NCT06216704
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Magnetic resonance relaxometry, Magnetic resonance spectroscopy, Blood Draw, DXA, pQCT
Diagnostic Test
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
13 Years to 20 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Sep 6, 2026, 2:22 AM EDT
Completed No phase listed Observational

Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain

NCT01862731
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 55 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 6, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Obesity and Cartilage Compression in Knees

NCT04730557
View directory record Official record
Conditions
Obesity, Osteoarthritis, Knee Osteoarthritis
Interventions
Weight Loss
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 45 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Sep 6, 2026, 2:22 AM EDT
Recruiting No phase listed Observational

Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee

NCT05700682
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Osteo Arthritis Shoulders, Synovitis of Knee, Synovitis/Tenosynovitis - Hip, Synovitis, Pain, Chronic
Interventions
Shoulder/Hip/Knee Embolization with Embozene Microspheres
Device
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
25 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 6, 2026, 2:22 AM EDT