- Conditions
- Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee
- Interventions
- Cebranopadol (GRT6005) Low-Dose Range, Cebranopadol (GRT6005) High-Dose Range, Placebo, Oxycodone CR
- Drug
- Lead sponsor
- Tris Pharma, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 619 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 83
- States / cities
- Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 74 more
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 73–96
of 865
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Osteoarthritis, Knee
- Interventions
- LY2951742, Placebo- oral, Placebo - SC, Celecoxib
- Drug · Other
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 268 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 38
- States / cities
- Birmingham, Alabama • Anaheim, California • San Diego, California + 31 more
- Conditions
- Knee Arthroplasty
- Interventions
- Total Knee Arthroplasty, MAKO® Robot Assisted Medial Knee Arthroplasty, RESTORIS Multicompartmental Knee System, Depuy Knee Replacement System, Stryker® Knee Replacement System
- Procedure · Device
- Lead sponsor
- Northwest Surgical Specialists, Vancouver
- Other
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 62 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2023
- U.S. locations
- 1
- States / cities
- Vancouver, Washington
- Conditions
- Osteoarthritis, Knee
- Interventions
- sc-rAAV2.5IL-1Ra
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Hip and Knee Osteoarthritis
- Interventions
- Procedural, Bone Marrow concentrate injection
- Other
- Lead sponsor
- Regenerative Pain Center, Illinois
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Des Plaines, Illinois
- Conditions
- Osteoarthritis, Knee
- Interventions
- Dexamethasone
- Drug
- Lead sponsor
- Mark Figgie
- Other
- Eligibility
- 40 Years to 99 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Rheumatoid Arthritis, Osteoarthritis
- Interventions
- yoga
- Behavioral
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Knee Osteoarthritis
- Interventions
- Pain Coping Skills Training, Arthritis Education, Usual Care
- Behavioral · Other
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 402 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2018
- U.S. locations
- 5
- States / cities
- Springfield, Illinois • New York, New York • Durham, North Carolina + 2 more
- Conditions
- Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of the Knee, Avascular Necrosis, Patellofemoral Osteoarthritis
- Interventions
- Zimmer Biomet Persona Ti-Nidium Total Knee System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2034
- U.S. locations
- 7
- States / cities
- Parker, Colorado • Hyattsville, Maryland • Jackson, Mississippi + 4 more
- Conditions
- Osteoarthritis
- Interventions
- AGG-523 (Aggrecanase Inhibitor)
- Drug
- Lead sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
- Industry
- Eligibility
- 55 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 5
- States / cities
- Boston, Massachusetts • Newton, Massachusetts • Winchester, Massachusetts + 1 more
- Conditions
- Osteoarthritis
- Interventions
- High Intensity Short Duration Exercise, Low intensity Long Duration Exercise
- Procedure
- Lead sponsor
- Regis University
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015
- U.S. locations
- 1
- States / cities
- Denver, Colorado
- Conditions
- Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 40 Years to 90 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2025
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Knee Osteoarthritis
- Interventions
- Subject outcomes following viscosupplementation of the knee
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 21 Years to 85 Years
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Osteoarthritis, Knee
- Interventions
- RAPTOR protocol: hybrid in-person + telehealth physical therapy services
- Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Knee Osteoarthritis
- Interventions
- Placebo, SM04690
- Drug
- Lead sponsor
- Biosplice Therapeutics, Inc.
- Industry
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 101 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 13
- States / cities
- Phoenix, Arizona • Canoga Park, California • Carmichael, California + 9 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Stepped Exercise Program, Arthritis Education
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 345 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Knee Osteoarthristis
- Interventions
- Physical Rehab, Focused Shockwave Therapy
- Other · Device
- Lead sponsor
- Pulse Wave USA
- Industry
- Eligibility
- Not listed
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2028
- U.S. locations
- 1
- States / cities
- Westminster, Colorado
- Conditions
- Osteoarthritis, Pain
- Interventions
- Placebo, Fulranumab 1 mg, Fulranumab 3 mg
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 41 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 7
- States / cities
- El Cajon, California • Sherman Oaks, California • Miami, Florida + 4 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Educational handout, Verbal script, Hyaluronic Acid
- Other · Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis of the Knee
- Interventions
- FX006 32 mg, TCA IR 40
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 81 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 4
- States / cities
- Canoga Park, California • San Diego, California • Hialeah, Florida + 1 more
- Conditions
- Knee Osteoarthritis
- Interventions
- CyMedica e-vive NMES
- Device
- Lead sponsor
- CyMedica Orthopedics, Inc
- Industry
- Eligibility
- 21 Years to 85 Years
- Enrollment
- 159 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 2
- States / cities
- Tucson, Arizona
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip
- Interventions
- Celecoxib
- Drug
- Lead sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 875 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2008
- U.S. locations
- 67
- States / cities
- Huntsville, Alabama • Peoria, Arizona • Phoenix, Arizona + 58 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- hylan G-F 20, 1% sodium hyaluronate
- Device
- Lead sponsor
- American Orthopaedic Society for Sports Medicine
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 198 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 1
- States / cities
- Portsmouth, Virginia
- Conditions
- Osteoarthritis
- Interventions
- PN 400 (VIMOVO), celebrex, Placebo, Rescue Antacid
- Drug
- Lead sponsor
- POZEN
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 614 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina