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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: L. reuteri Clear all
Completed Phase 1 Interventional Results available

Biological Signatures, Probiotic Among Those With mTBI and PTSD

NCT02723344
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Post Traumatic Stress Disorder
Interventions
of Lactobacillus reuteri (L. reuteri; DSM 17938), Sunflower and medium chain triglyceride oils
Dietary Supplement · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 50 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 17, 2020 · Synced Sep 10, 2026, 8:12 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety and Effect of L. Reuteri on Biomarkers of Inflammation in Healthy Infants With Colic

NCT01849991
View directory record Official record
Conditions
Gastrointestinal, Colic
Interventions
Lactobacillus reuteri, Placebo
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
3 Weeks to 3 Months
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Sep 10, 2026, 8:12 PM EDT
Not yet recruiting Not applicable Interventional

Probiotic Milk Drink for Gut and Brain Health in Older Adults and Caregivers

NCT07800195
View directory record Official record
Conditions
Alzheimer Disease Related Dementia
Interventions
Probiotic Fermented Milk (PFM) Drink, Placebo
Dietary Supplement
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 10, 2026, 8:12 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Control of Colic in Infants by Dietary Supplementation With the Probiotic Lactobacillus Reuteri

NCT01067027
View directory record Official record
Conditions
Colic
Interventions
Lactobacillus reuteri
Dietary Supplement
Lead sponsor
Children's Investigational Research Program, LLC
Other
Eligibility
14 Days to 60 Days
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Bentonville, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 28, 2011 · Synced Sep 10, 2026, 8:12 PM EDT
Completed Not applicable Interventional

The Effects of Probiotic Supplementation on State and Trait Stress, Anxiety, and Depression Symptoms in Stressed Adults

NCT07216729
View directory record Official record
Conditions
Anxiety Symptoms, Perceived Stress, Depressive Symptoms
Interventions
Lactobacillus reuteri DSM 17938, Placebo
Dietary Supplement · Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 45 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Sep 10, 2026, 8:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Oral Probiotic Supplementation on Group B Strep (GBS) Rectovaginal Colonization in Pregnancy

NCT01479478
View directory record Official record
Conditions
Infection, Pregnancy
Interventions
Placebo, Probiotic dietary supplement
Drug · Dietary Supplement
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
251 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
3
States / cities
Aptos, California • Santa Cruz, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2018 · Synced Sep 10, 2026, 8:12 PM EDT
Withdrawn Phase 2 Interventional

Probiotics in Girls With Spina Bifida

NCT00767988
View directory record Official record
Conditions
Urinary Tract Infection
Interventions
Urex-cap-5 (2x10^9 cfu each of Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1), Placebo
Dietary Supplement · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
3 Months to 17 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2015 · Synced Sep 10, 2026, 8:12 PM EDT
Completed Not applicable Interventional

A Study to Evaluate the Effects of a Prebiotic and Probiotic Supplement to Provide Relief From Symptoms Associated With Bacterial Vaginosis and Yeast Infections.

NCT06665126
View directory record Official record
Conditions
Bacterial Vaginosis, Yeast Infection
Interventions
Prebiotic + Probiotic Supplement, Active Placebo Supplement, Excipient Placebo Supplement
Dietary Supplement
Lead sponsor
Happy V
Industry
Eligibility
25 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 10, 2026, 8:12 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety of Lactobacillus Reuteri (L. Reuteri) in Healthy Adults

NCT00922727
View directory record Official record
Conditions
Colic, Gastrointestinal Tract Infections
Interventions
L. reuteri, Sunflower Oil
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Sep 10, 2026, 8:12 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Precision Microbiota Interventions for Senoreduction Trial

NCT07462767
View directory record Official record
Conditions
HIV Infections, Alcohol Drinking, Aging, Immunosenescence
Interventions
Limosilactobacillus reuteri, Blueberry extract
Dietary Supplement
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
40 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 10, 2026, 8:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Probiotics, Immunity, Stress, and QofL

NCT05063305
View directory record Official record
Conditions
Stress, Quality of Life
Interventions
Probiotic, Placebo
Dietary Supplement
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Sep 10, 2026, 8:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Probiotic Supplementation on Immune Function in Healthy Infants

NCT01542320
View directory record Official record
Conditions
Inflammation
Interventions
Lactobacillus reuteri DSM 17938, Placebo
Dietary Supplement · Other
Lead sponsor
Emory University
Other
Eligibility
6 Weeks to 32 Weeks
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 5, 2015 · Synced Sep 10, 2026, 8:12 PM EDT
Completed Not applicable Interventional

Lactobacillus Reuteri in the Prevention of Antibiotic Associated-diarrhea and Clostridium Difficile

NCT02127814
View directory record Official record
Conditions
Antibiotic-associated Diarrhea, Clostridium Difficile
Interventions
Lactobacillus reuteri
Dietary Supplement
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Sep 10, 2026, 8:12 PM EDT
Completed Not applicable Interventional

Study of Probiotic Use After Childbirth in Relation to Emotional Well-Being

NCT04472065
View directory record Official record
Conditions
Mental Health Wellness
Interventions
Lactobacillus reuteri, Placebo
Dietary Supplement · Other
Lead sponsor
Elizabeth Austen Lawson
Other
Eligibility
18 Years and older · Female only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 24, 2023 · Synced Sep 10, 2026, 8:12 PM EDT
Not listed Not applicable Interventional

Assess the Effects of a Limosilactobacillus Supplement on Recurrence of UTI in Healthy Women During a 6-month Period

NCT05793814
View directory record Official record
Conditions
Uncomplicated Symptomatic Urinary Tract Infections
Interventions
Limosilactobacillus reuteri 3613, Placebo
Dietary Supplement
Lead sponsor
Church & Dwight Company, Inc.
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Sep 10, 2026, 8:12 PM EDT
Completed Phase 1 Interventional Results available

28-Day Daily-dose Crossover Study of the Safety and Tolerability of SB-121 (Lactobacillus Reuteri With Sephadex® and Maltose) in Subjects, Ages 15 to 45 Years, Diagnosed With Autistic Disorder

NCT04944901
View directory record Official record
Conditions
Autistic Disorder
Interventions
SB-121, Placebo
Drug
Lead sponsor
Scioto Biosciences, Inc.
Industry
Eligibility
15 Years to 45 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 24, 2024 · Synced Sep 10, 2026, 8:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Limosilactobacillus Reuteri DSM 17648 in Healthy Adults Reporting Upper Gastrointestinal Discomfort

NCT07163637
View directory record Official record
Conditions
Healthy Participants, Upper Gastrointestinal Discomfort
Interventions
Limosilactobacillus reuteri DSM 17648, Placebo
Dietary Supplement
Lead sponsor
Novozymes A/S
Industry
Eligibility
30 Years to 70 Years
Enrollment
324 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 10, 2026, 8:12 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Baby 2 Baby Beneficial Bacteria

NCT05703659
View directory record Official record
Conditions
Transmission
Interventions
B. longum subsp. infantis, L. reuteri probiotic
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 62 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Sep 10, 2026, 8:12 PM EDT
Withdrawn Phase 2 Interventional

Probiotics for Girls With Recurring Urinary Tract Infections

NCT00789464
View directory record Official record
Conditions
Recurrent Urinary Tract Infection
Interventions
Lactobacillus reuteri DSM 17938, trimethoprim/sulfamethoxazole
Dietary Supplement · Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
3 Months to 17 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 17, 2020 · Synced Sep 10, 2026, 8:12 PM EDT
Not listed Phase 1 Interventional

Bacteriuria Eradication Through Probiotics

NCT00717600
View directory record Official record
Conditions
Bacteriuria
Interventions
Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1
Dietary Supplement
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 18 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 16, 2008 · Synced Sep 10, 2026, 8:12 PM EDT