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ClinicalTrials.gov public records Last synced Oct 17, 2026, 10:45 AM EDT

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Showing 1–24 of 110 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: LASIK Clear all
Withdrawn Not applicable Interventional

The Effect of Hinge Position and Hinge Width on Corneal Sensation and Dry Eye After IntraLase LASIK Procedure

NCT00803478
View directory record Official record
Conditions
Myopia
Interventions
LASIK
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 3, 2016 · Synced Oct 17, 2026, 10:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Patient Satisfaction in Post-LASIK Patients With Presbyopia-Correcting IOLs vs. Post-Lasik Patients With Monofocal IOLs

NCT04134507
View directory record Official record
Conditions
Patient Satisfaction
Interventions
Not listed
Lead sponsor
Bucci Laser Vision Institute
Other
Eligibility
Not listed
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 17, 2020 · Synced Oct 17, 2026, 10:45 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Evaluation of the Post-LASIK Flap Thickness of the FS200 Femtosecond Laser Flap

NCT01693939
View directory record Official record
Conditions
Myopia
Interventions
FS200 Femtosecond Laser
Device
Lead sponsor
Durrie Vision
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 25, 2013 · Synced Oct 17, 2026, 10:45 AM EDT
Active, not recruiting Not applicable Interventional

LASIK iDesign vs SMILE

NCT07126756
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
STAR S4 IR Excimer Laser System, VisuMax 400 Surgical Laser
Device
Lead sponsor
59th Medical Wing
Federal
Eligibility
21 Years to 50 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Lackland Air Force Base, Texas
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 17, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism

NCT07201298
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Ray-Tracing Guided LASIK, Keratorefractive Lenticule Extraction (KLEx), WaveFront Optimized LASIK, Topography Guided LASIK
Device
Lead sponsor
Hoopes Vision
Other
Eligibility
22 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Draper, Utah
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 17, 2026, 10:45 AM EDT
Withdrawn Not applicable Interventional

Higher Irradiance in Keratoconus Ectasia

NCT01789333
View directory record Official record
Conditions
Keratoconus, Ectasia
Interventions
UVA Light with irradiance exposure of 9 mW/cm2, Riboflavin 0.1% ophthalmic solution
Device · Drug
Lead sponsor
Stephen Trokel
Other
Eligibility
16 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Oct 17, 2026, 10:45 AM EDT
Completed Phase 4 Interventional

Efficacy of Cyclosporine for the Prevention and Treatment of Dry Eye Symptoms Following LASIK or Photorefractive Keratectomy

NCT00349440
View directory record Official record
Conditions
Dry Eye Syndromes
Interventions
Cyclosporine, Refresh Plus
Drug
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 26, 2008 · Synced Oct 17, 2026, 10:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High Resolution Wavefront-guided vs. Wavefront Optimized LASIK

NCT02565537
View directory record Official record
Conditions
Nearsightedness, Astigmatism
Interventions
LASIK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 17, 2026, 10:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Lacritin and Heparanase Levels in Human Tears After Laser Refractive Surgery

NCT01049724
View directory record Official record
Conditions
Myopia
Interventions
Tear collection
Other
Lead sponsor
Fort Belvoir Community Hospital
Federal
Eligibility
21 Years to 55 Years
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 7, 2018 · Synced Oct 17, 2026, 10:45 AM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Safety and Effectiveness of the Technols 217z Zyoptix System for Hyperopia

NCT00348205
View directory record Official record
Conditions
Hyperopia, Astigmatism
Interventions
Technolas 217z Zyoptix Laser
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 14, 2020 · Synced Oct 17, 2026, 10:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Quality of Vision and Quality of Life With LASIK

NCT02161263
View directory record Official record
Conditions
Myopia, Astigmatism, Quality of Lifte
Interventions
Patient Quality of Life andVision after LASIK Surgery
Other
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Oct 17, 2026, 10:45 AM EDT
Completed Not applicable Interventional

Comparison of LASIK and SBK

NCT00714363
View directory record Official record
Conditions
Myopia
Interventions
LASIK, SBK
Procedure
Lead sponsor
University of Utah
Other
Eligibility
21 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 19, 2010 · Synced Oct 17, 2026, 10:45 AM EDT
Completed Not applicable Interventional Results available

A Study With Technolas® TENEO 317 Model 2 Excimer Laser to Treat Participants With Myopia or Myopic Astigmatism

NCT04111757
View directory record Official record
Conditions
Myopia, Myopic Astigmatism
Interventions
Technolas® TENEO 317 Model 2
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
22 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
10
States / cities
Newport Beach, California • Blaine, Minnesota • Bloomington, Minnesota + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2024 · Synced Oct 17, 2026, 10:45 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Tissue Sealant Use in LASIK Enhancement Surgery

NCT02952365
View directory record Official record
Conditions
Epithelial Ingrowth
Interventions
Tissue sealant
Drug
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 99 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Oct 17, 2026, 10:45 AM EDT
Terminated Phase 2 Interventional

CXL-04 A Study of Collagen Crosslinking With Ultraviolet-A in Asymmetric Corneas

NCT01956474
View directory record Official record
Conditions
Keratoconus
Interventions
Theralight crosslinking and Riboflavin
Other
Lead sponsor
Cxlusa
Industry
Eligibility
8 Years and older
Enrollment
1,324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
6
States / cities
Miami, Florida • Atlanta, Georgia • Rockville, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 12, 2018 · Synced Oct 17, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

Contoura With Phorcides Compared to Wavefront Optimized LASIK

NCT05486546
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Contoura with Phorcides, WaveLight Wavefront Optimized
Procedure · Device
Lead sponsor
Daniel Terveen
Other
Eligibility
21 Years to 38 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Bozeman, Montana • Omaha, Nebraska • Fargo, North Dakota + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 17, 2026, 10:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Test the Potential of Brillouin Microscopy for Biomechanical Properties Measurements in Human Cornea

NCT03220529
View directory record Official record
Conditions
Pellucid Marginal Corneal Degeneration, Keratoconus, Keratectasia
Interventions
Brillouin Ocular Scanner
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
15 Years to 75 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced Oct 17, 2026, 10:45 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Efficacy of Kera Sol Tears on Signs and Symptoms of Surgical Temporary Ocular Discomfort Syndrome (STODS) in Subjects Following LASIK

NCT07155070
View directory record Official record
Conditions
Dry Eye
Interventions
Kera Sol Eye Drops
Drug
Lead sponsor
Vance Thompson Vision
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 17, 2026, 10:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Wavefront-Guided LASIK Correction of Hyperopic Refractive Errors

NCT01675479
View directory record Official record
Conditions
Hyperopia
Interventions
LASIK correction of hyperopic refractive errors
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
9
States / cities
Los Angeles, California • Miami, Florida • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Oct 17, 2026, 10:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Prospective Comparison of Alcon LADARVision Wavefront-guided LASIK Enhancement and Conventional LASIK Enhancement for the Correction of Residual Refractive Errors Following LASIK Procedures

NCT00413881
View directory record Official record
Conditions
Refractive Errors
Interventions
WAVEFRONT- GUIDED LASIK ENHANCEMENT, CONVENTIONAL LASIK ENHANCEMENT
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 14, 2010 · Synced Oct 17, 2026, 10:45 AM EDT
Terminated Phase 2 Interventional Results available

Collagen Cross-Linking With Ultraviolet-A in Asymmetric Corneas

NCT03029104
View directory record Official record
Conditions
Keratoconus, Corneal Diseases, Eye Diseases, Photosensitizing Agents
Interventions
CXLO Corneal Strengthening Solution and UVA Illumination Device
Combination Product
Lead sponsor
Cxlusa
Industry
Eligibility
8 Years and older
Enrollment
2,228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
9
States / cities
Scottsdale, Arizona • San Francisco, California • Littleton, Colorado + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2022 · Synced Oct 17, 2026, 10:45 AM EDT
Completed No phase listed Observational

Patient Reported Outcomes With WaveLight Plus LASIK

NCT07087665
View directory record Official record
Conditions
Myopia
Interventions
Wavelight Plus
Device
Lead sponsor
OVO LASIK + Lens
Other
Eligibility
18 Years to 37 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Saint Louis Park, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 17, 2026, 10:45 AM EDT
Active, not recruiting Not applicable Interventional

LASIK Using Contoura With Phorcides vs. iDesign

NCT07128316
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Contoura Topolyzer with Phorcides, iDesign
Device
Lead sponsor
59th Medical Wing
Federal
Eligibility
21 Years to 50 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Oct 17, 2026, 10:45 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Safety and Efficacy Study of Topography-Guided LASIK to Treat Myopia and Hyperopia

NCT01028378
View directory record Official record
Conditions
Myopia, Hyperopia
Interventions
T-CAT topography-guided LASIK treatment with the Allegretto Wave Eye-Q 400 Hz Excimer Laser
Device
Lead sponsor
Clinical Research Consultants, Inc.
Industry
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
10
States / cities
La Quinta, California • San Diego, California • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 11, 2016 · Synced Oct 17, 2026, 10:45 AM EDT