Independent directory Public ClinicalTrials.gov records United States
Clear filters
ClinicalTrials.gov public records Last synced Sep 2, 2026, 1:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 109 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 4 Interventional Accepts healthy volunteers

Visual Outcomes and Contrast Sensitivity After Myopic LASIK

NCT01746589
Conditions
Myopia
Interventions
bilateral myopic LASIK
Device
Lead sponsor
Daniel S. Durrie, MD
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Overland Park, Kansas
Conditions
Myopia, Hypermetropia, Refractive Errors, Astigmatism
Interventions
Proparacaine Ophthalmic
Drug
Lead sponsor
Beeran Meghpara, MD
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Epi-lasik in U.S. Army Personnel

NCT00413517
Conditions
Myopia
Interventions
Epi-Lasik
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Not listed Phase 2 Interventional Accepts healthy volunteers

Bandage Contact Lenses for Corneal Abrasions

NCT03206723
Conditions
Corneal Abrasion, Eye Trauma
Interventions
Bandage contact lens, Eyedrop, Hydrocodone
Device · Drug
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Torrance, California
Conditions
Pellucid Marginal Corneal Degeneration, Keratoconus, Keratectasia
Interventions
Brillouin Ocular Scanner
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
15 Years to 75 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Myopia
Interventions
LASIK
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Myopia
Interventions
Laser-assisted in Situ Keratomileusis, Implantable Collamer Lens placement
Device
Lead sponsor
Vance Thompson Vision
Other
Eligibility
21 Years to 45 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
5
States / cities
Omaha, Nebraska • Cleveland, Ohio • Mt. Pleasant, South Carolina + 2 more
Conditions
Keratoconus
Interventions
Theralight crosslinking and Riboflavin
Other
Lead sponsor
Cxlusa
Industry
Eligibility
8 Years and older
Enrollment
1,324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
6
States / cities
Miami, Florida • Atlanta, Georgia • Rockville, Maryland + 3 more
Conditions
Myopia
Interventions
LASIK, PRK, Small target contrast sensitivity and disability glare
Procedure · Behavioral
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Not applicable Interventional Accepts healthy volunteers

Goblet Cell Response and Dry Eye Symptoms After PRK and LASIK

NCT00411827
Conditions
Keratoconjunctivitis Sicca
Interventions
PRK with conjunctival impression cytology before and after surgery, LASIK with conjunctival impression cytology before and after surgery
Procedure
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
21 Years to 40 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Not applicable Interventional Accepts healthy volunteers

Wavefront-guided vs. Topography-guided LASIK

NCT05588882
Conditions
Myopia
Interventions
Wavefront-guided LASIK, Wavefront-guided
Procedure
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 59 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Hyperopia
Interventions
TENEO 317 Model 2 excimer laser
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
22 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
9
States / cities
Newport Beach, California • Fort Myers, Florida • Bloomington, Minnesota + 6 more
Conditions
Myopia, Astigmatism
Interventions
WaveLight EX500 Excimer Laser System, VisuMax Surgical Laser
Device
Lead sponsor
59th Medical Wing
Federal
Eligibility
21 Years to 50 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Myopia
Interventions
WaveLight EX500 excimer laser system with InnovEyes sightmap, LASIK, InnovEyes sightmap
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
9
States / cities
San Diego, California • Indianapolis, Indiana • Chevy Chase, Maryland + 6 more
Conditions
Presbyopia, Pseudophakia
Interventions
Raindrop Near Vision Inlay
Device
Lead sponsor
ReVision Optics, Inc.
Industry
Eligibility
50 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
13
States / cities
Laguna Hills, California • Orange, California • Bradenton, Florida + 10 more
Completed Phase 2 Interventional Results available

Study of Cyclosporine in Post-LASIK Patients

NCT00991458
Conditions
Laser In Situ Keratomileusis
Interventions
Cyclosporine 0.010% eye drops, Cyclosporine 0.005% eye drops, Placebo (Vehicle for Cyclosporine)
Drug
Lead sponsor
Allergan
Industry
Eligibility
21 Years to 50 Years
Enrollment
621 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Overland Park, Kansas
Conditions
Patient Satisfaction
Interventions
Not listed
Lead sponsor
Bucci Laser Vision Institute
Other
Eligibility
Not listed
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Conditions
Refractive Errors
Interventions
WAVEFRONT- GUIDED LASIK ENHANCEMENT, CONVENTIONAL LASIK ENHANCEMENT
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Astigmatism, Myopia
Interventions
Wavelight Plus
Device
Lead sponsor
Vance Thompson Vision
Other
Eligibility
18 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Completed No phase listed Observational Accepts healthy volunteers

Quality of Vision and Quality of Life With LASIK

NCT02161263
Conditions
Myopia, Astigmatism, Quality of Lifte
Interventions
Patient Quality of Life andVision after LASIK Surgery
Other
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Dry Eye Syndromes
Interventions
Cyclosporine, Refresh Plus
Drug
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Greensboro, North Carolina
Conditions
Hyperopia
Interventions
MEL 80 Hyperopic LASIK Treatment
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
21 Years and older
Enrollment
189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
6
States / cities
San Diego, California • Greenwood Village, Colorado • Kansas City, Missouri + 3 more
Conditions
Hyperopia, Myopia, Astigmatism
Interventions
LASIK and PRK
Procedure
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years to 60 Years
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2022
U.S. locations
1
States / cities
Stanford, California
Conditions
Keratoconus, Corneal Diseases, Eye Diseases, Photosensitizing Agents
Interventions
CXLO Corneal Strengthening Solution and UVA Illumination Device
Combination Product
Lead sponsor
Cxlusa
Industry
Eligibility
8 Years and older
Enrollment
2,228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
9
States / cities
Scottsdale, Arizona • San Francisco, California • Littleton, Colorado + 6 more