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ClinicalTrials.gov public records Last synced Sep 4, 2026, 8:47 PM EDT

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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Dry Eye Syndromes
Interventions
Optive
Drug
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fullerton, California
Conditions
Myopia
Interventions
LASIK, PRK, Small target contrast sensitivity and disability glare
Procedure · Behavioral
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Cataract
Interventions
Vivity IOL
Device
Lead sponsor
Laser & Corneal Surgery Associates
Other
Eligibility
40 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
New York, New York • White Plains, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

CONTOURA vs WFO Ablation PRK & LASIK

NCT05037370
Conditions
Refractive Surgery
Interventions
Wave-Front Optimized (WFO) ablation vs Topography-guided (TG) ablation
Device
Lead sponsor
59th Medical Wing
Federal
Eligibility
21 Years to 50 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Keratoconus, Ectasia, Crosslinking, Fuchs' Endothelial Dystrophy
Interventions
Brillouin imaging
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
20 Years to 75 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Goblet Cell Response and Dry Eye Symptoms After PRK and LASIK

NCT00411827
Conditions
Keratoconjunctivitis Sicca
Interventions
PRK with conjunctival impression cytology before and after surgery, LASIK with conjunctival impression cytology before and after surgery
Procedure
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
21 Years to 40 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Dry Eye Syndromes
Interventions
Cyclosporine, Refresh Plus
Drug
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Greensboro, North Carolina
Conditions
Myopia, Astigmatism
Interventions
WaveLigh Plus LASIK
Device
Lead sponsor
Mann Eye Institute
Other
Eligibility
18 Years to 39 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Conditions
Chronic Ocular Pain
Interventions
SAF312 Placebo, SAF312
Other · Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
24
States / cities
Mission Hills, California • Newport Beach, California • Palo Alto, California + 19 more
Recruiting No phase listed Observational Accepts healthy volunteers

An Evaluation of LASIK, SMILE and PRK Surgery in Physicians

NCT02576483
Conditions
Nearsightedness, Farsightedness, Astigmatism
Interventions
Questionnaire (QoV questionnaire)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 62 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Completed No phase listed Observational Accepts healthy volunteers

Lacritin and Heparanase Levels in Human Tears After Laser Refractive Surgery

NCT01049724
Conditions
Myopia
Interventions
Tear collection
Other
Lead sponsor
Fort Belvoir Community Hospital
Federal
Eligibility
21 Years to 55 Years
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Fort Belvoir, Virginia
Not listed Phase 2 Interventional Accepts healthy volunteers

Bandage Contact Lenses for Corneal Abrasions

NCT03206723
Conditions
Corneal Abrasion, Eye Trauma
Interventions
Bandage contact lens, Eyedrop, Hydrocodone
Device · Drug
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Torrance, California
Conditions
Myopia, Myopic Astigmatism
Interventions
WFG PRK, WFG LASIK, WFO PRK, WFO LASIK
Procedure
Lead sponsor
Fort Belvoir Community Hospital
Federal
Eligibility
21 Years to 55 Years
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Not listed No phase listed Observational Accepts healthy volunteers

Panoptix Trifocal Lens in Post Refractive Myopic Laser Vision Correction Surgery

NCT04698278
Conditions
Cataract, Refractive Errors
Interventions
PanOptix Trifocal Intraocular Lens
Device
Lead sponsor
Parkhurst NuVision Clinical Research LLC
Other
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Myopia, Astigmatism
Interventions
Wavelight Plus LASIK
Device
Lead sponsor
Laser Defined Vision
Other
Eligibility
18 Years and older
Enrollment
50 participants
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greensboro, North Carolina
Enrolling by invitation No phase listed Observational

Corneal Biomechanical Analysis Using Brillouin Microscopy

NCT04598932
Conditions
Keratoconus, Keratoconus, Unstable, Keratoconus, Stable
Interventions
Brillouin microscopy
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 60 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Surgery, Myopia
Interventions
Wavefront optimized LASIK, Wavefront optimized Photorefractive Keratectomy, Topography-guided LASIK, Topography-guided Photorefractive Keratectomy
Device
Lead sponsor
University of Utah
Other
Eligibility
21 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Murray, Utah
Conditions
Myopia, Hypermetropia, Refractive Errors, Astigmatism
Interventions
Proparacaine Ophthalmic
Drug
Lead sponsor
Beeran Meghpara, MD
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Fruste Keratoconus, Risk of Ectasia
Interventions
Corneal Cross-Linking, Riboflavin
Device · Drug
Lead sponsor
Cxlusa
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
8
States / cities
Scottsdale, Arizona • San Diego, California • Miami, Florida + 5 more
Conditions
Hyperopia, Myopia, Astigmatism
Interventions
LASIK and PRK
Procedure
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years to 60 Years
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2022
U.S. locations
1
States / cities
Stanford, California
Conditions
Corneal Diseases
Interventions
Not listed
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
18 Years and older
Enrollment
769 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
4
States / cities
La Jolla, California • San Diego, California • Greenwood Village, Colorado + 1 more
Conditions
Binocular Vision Disorder, Refractive Errors, Cataract
Interventions
cataract surgery, Corneal refractive surgery
Procedure
Lead sponsor
Salus University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Elkins Park, Pennsylvania