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ClinicalTrials.gov public records Last synced Oct 25, 2026, 2:20 PM EDT

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Showing 1–24 of 156 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: LED phototherapy Clear all
Completed Phase 1 Interventional

Photobiomodulation to Alter Cerebral Blood Flow and to Affect the Emotional Status of Patients With Major Depression

NCT00961454
View directory record Official record
Conditions
Major Depression, Anxiety Disorder, Post-Traumatic Stress Disorder, Substance Abuse Disorder
Interventions
Photobiomodulation with a super-luminous light emitting diode
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2009 · Synced Oct 25, 2026, 2:20 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Red Light LED Therapy on Body Contouring

NCT03470272
View directory record Official record
Conditions
Obesity
Interventions
FB Professional LED Red light therapy, Effects of Red Light LED Therapy on Body Contouring
Device
Lead sponsor
Manamed Inc.
Industry
Eligibility
18 Years to 77 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
New Port Richey, Florida
Source: ClinicalTrials.gov public record
Updated Aug 17, 2018 · Synced Oct 25, 2026, 2:20 PM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate the Safety, Tolerability and Efficacy of BF-200 ALA (Ameluz®) in the Field-directed Treatment of Actinic Keratosis (AK) on the Extremities and Neck/Trunk With Photodynamic Therapy (PDT) Using a RhodoLED Lamp

NCT05662202
View directory record Official record
Conditions
Actinic Keratoses
Interventions
BF-200 ALA and red light LED lamp, Vehicle and red light LED lamp
Combination Product
Lead sponsor
Biofrontera Inc.
Industry
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
14
States / cities
Phoenix, Arizona • Greenwood Village, Colorado • Delray Beach, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 25, 2026, 2:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Combined Blue and Red Home-Based Light Therapy on Sleep in Adults With Self-Reported Sleep Difficulties

NCT07465250
View directory record Official record
Conditions
Sleep
Interventions
LED portable light therapy bulb
Other
Lead sponsor
Colorado State University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 25, 2026, 2:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Red Light LED Therapy on Body Contouring

NCT03242564
View directory record Official record
Conditions
Obesity
Interventions
Vevazz LED
Device
Lead sponsor
Vevazz, LLC
Industry
Eligibility
18 Years to 77 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2017 · Synced Oct 25, 2026, 2:20 PM EDT
Not listed Early Phase 1 Interventional

Photobiomodulation to Improve Cognition in TBI, With fMRI

NCT04230577
View directory record Official record
Conditions
Traumatic Brain Injury, Closed Head Injury, Cognitive Dysfunction
Interventions
Real LED Intervention, Sham LED Intervention
Device
Lead sponsor
Boston VA Research Institute, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 25, 2022 · Synced Oct 25, 2026, 2:20 PM EDT
Completed Not applicable Interventional

LED Photomodulation for Prevention of Post-Radiation Treatment Dermatitis

NCT00573365
View directory record Official record
Conditions
Radiation Dermatitis
Interventions
Gentlewaves Select™ handheld high energy LED array, Radiation
Device · Radiation
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 2, 2017 · Synced Oct 25, 2026, 2:20 PM EDT
Not yet recruiting Not applicable Interventional

Testing a Peer-Support Group for Veterans Who Hear Voices

NCT07555275
View directory record Official record
Conditions
Psychotic Disorders, Hallucinations, Auditory, Social Isolation
Interventions
Veteran Voices and Visions (VVV), Wellness Recovery Action Planning (WRAP)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
2
States / cities
West Los Angeles, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 25, 2026, 2:20 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin

NCT02630303
View directory record Official record
Conditions
Fibrosis, Scarring, Scar, Wounds, Injuries, Keloid, Cicatrix, Hypertrophic
Interventions
LED-RL Phototherapy, Mock Therapy
Device
Lead sponsor
Jared Jagdeo, MD, MS
Federal
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Mar 31, 2017 · Synced Oct 25, 2026, 2:20 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)

NCT07496918
View directory record Official record
Conditions
Cognitively Healthy People, Alzheimer Disease
Interventions
GENUS, Tactile GENUS
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 25, 2026, 2:20 PM EDT
Completed Not applicable Interventional

Evaluation of the Efficacy of a Cosmetic Light Mask

NCT07054710
View directory record Official record
Conditions
Fine Lines, Contour, Sagging Skin, Dark Spots, Wrinkles, Firmness, Skin Tone, Radiance/Luminosity
Interventions
LED Light Treatment, Vibration Only
Device
Lead sponsor
Therabody, Inc.
Industry
Eligibility
35 Years to 65 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 25, 2026, 2:20 PM EDT
Withdrawn Not applicable Interventional

LED Light Therapy to Improve Cognitive & Psychosocial Function in TBI-PTSD Veterans

NCT02356861
View directory record Official record
Conditions
Traumatic Brain Injury (TBI), Post-traumatic Stress Disorder (PTSD)
Interventions
Photomedex Sham Helmet with Red/Near-Infrared Light-Emitting Diodes (LEDs) that are not turned on
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Oct 25, 2026, 2:20 PM EDT
Completed Not applicable Interventional Results available

Body Mind Training Project

NCT01564394
View directory record Official record
Conditions
Cancer Related Fatigue
Interventions
Qigong, Non-aerobic stretching
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
55 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 8, 2015 · Synced Oct 25, 2026, 2:20 PM EDT
Completed Not applicable Interventional Results available

LED Therapy for the Treatment of Concussive Brain Injury

NCT02383472
View directory record Official record
Conditions
Brain Concussion
Interventions
MedX Health Console model 1100, MedX Health Console model 1100-placebo
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
11 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 26, 2018 · Synced Oct 25, 2026, 2:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examination of Circumferential Reduction

NCT04451824
View directory record Official record
Conditions
Overweight or Obesity
Interventions
CL-100
Device
Lead sponsor
Contour Research
Industry
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
3
States / cities
Vista, California • Savannah, Georgia • Kirkland, Washington
Source: ClinicalTrials.gov public record
Updated Jun 30, 2020 · Synced Oct 25, 2026, 2:20 PM EDT
Recruiting Not applicable Interventional

Circadian Light Exposure Adjustment for Restfulness

NCT07391852
View directory record Official record
Conditions
Sleep Onset Latency
Interventions
Amber Tinted Glasses, Clear Glasses, Smart Lightbulbs
Device
Lead sponsor
University of Arizona
Other
Eligibility
60 Months to 83 Months
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 25, 2026, 2:20 PM EDT
Withdrawn Not applicable Interventional

LLLT Treatment of Lung Inflammation in COVID-19

NCT04524715
View directory record Official record
Conditions
Covid19
Interventions
Non-invasive red LLLT treatment to chest of patient., Sham Device Treatment
Device
Lead sponsor
Ward Photonics LLC
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Millsboro, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 18, 2022 · Synced Oct 25, 2026, 2:20 PM EDT
Terminated Not applicable Interventional Results available

Bright Light Therapy for Depression Symptoms in Adults With Cystic Fibrosis (CF) and COPD

NCT04921332
View directory record Official record
Conditions
Cystic Fibrosis, Depressive Symptoms, Chronic Obstructive Pulmonary Disease
Interventions
Bright Light Therapy (BLT) Lamp
Device
Lead sponsor
Erica Osborn
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Oct 25, 2026, 2:20 PM EDT
Not listed Phase 2Phase 3 Interventional

Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Previously Untreated Corneal Ulcers

NCT05255107
View directory record Official record
Conditions
Keratitis, Corneal Ulcer
Interventions
Standard of Care Therapy + CXL + Riboflavin 0.23% L Solution, Standard of Care Therapy + Sham CXL + Artificial Tears
Combination Product · Other
Lead sponsor
Peschke GmbH
Industry
Eligibility
18 Years and older
Enrollment
468 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Littleton, Colorado • Fort Myers, Florida • Tampa, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2022 · Synced Oct 25, 2026, 2:20 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Light Emitting Diode-Red Light (LED-RL) Phototherapy for Skin Scarring Prevention

NCT03795116
View directory record Official record
Conditions
Fibrosis, Skin Scarring, Skin Wound, Hypertrophic Scar, Scar, Keloid
Interventions
LED-RL phototherapy, Mock irradiation
Device
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2022 · Synced Oct 25, 2026, 2:20 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Vision Restoration With a Collagen Crosslinked Boston Keratoprosthesis Unit

NCT02863809
View directory record Official record
Conditions
Keratolysis
Interventions
Riboflavin, Dextran, UVA Light Source
Drug · Device
Lead sponsor
Joseph B. Ciolino, MD
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
13
States / cities
Los Angeles, California • Sacramento, California • San Diego, California + 10 more
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 25, 2026, 2:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study Evaluating the Efficacy and Safety of Omnilux Clear on Mitigating Mild to Moderate Acne

NCT06936332
View directory record Official record
Conditions
Acne
Interventions
Omnilux Clear Light Emitting Diode Treatment
Device
Lead sponsor
Ablon Skin Institute Research Center
Other
Eligibility
14 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Manhattan Beach, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2025 · Synced Oct 25, 2026, 2:20 PM EDT
Not yet recruiting Phase 3 Interventional

RB-PDT for Fusarium Keratitis: The LUMIERE Study

NCT07743489
View directory record Official record
Conditions
Fusarium Keratitis
Interventions
Rose Bengal Photodynamic Therapy, Sham RB-PDT
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
434 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
2
States / cities
Palo Alto, California • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 25, 2026, 2:20 PM EDT
Completed Not applicable Interventional Results available

Environmental Treatment for Seasonal Affective Disorder (SAD)

NCT00139997
View directory record Official record
Conditions
Seasonal Affective Disorder
Interventions
Litebook treatment devices, Inactivated negative ion generator
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 6, 2013 · Synced Oct 25, 2026, 2:20 PM EDT