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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: LED phototherapy Clear all
Withdrawn Not applicable Interventional

LLLT Treatment of Lung Inflammation in COVID-19

NCT04524715
View directory record Official record
Conditions
Covid19
Interventions
Non-invasive red LLLT treatment to chest of patient., Sham Device Treatment
Device
Lead sponsor
Ward Photonics LLC
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Millsboro, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 17, 2022 · Synced Sep 17, 2026, 12:54 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Assessing Environmental Factors in Healthcare Facilities in Order to Improve the Experience of Patients, Staff, and the Quality of Imaging Procedures

NCT03456895
View directory record Official record
Conditions
Healthcare Facility Environment - Imaging
Interventions
Light perception, Sound perception, Smell perception, Vibration perception, Voice activation
Other
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Sep 17, 2026, 12:54 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Phase 1 Study of HF-LED-RL in Fitzpatrick Skin Types I to III

NCT03433222
View directory record Official record
Conditions
Skin Diseases, Keloid, Scar, Fibrosis, Hypertrophic Skin
Interventions
HF-LED-RL Phototherapy, Mock Therapy
Device
Lead sponsor
VA Northern California Health Care System
Federal
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Sep 17, 2026, 12:54 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin

NCT02630303
View directory record Official record
Conditions
Fibrosis, Scarring, Scar, Wounds, Injuries, Keloid, Cicatrix, Hypertrophic
Interventions
LED-RL Phototherapy, Mock Therapy
Device
Lead sponsor
Jared Jagdeo, MD, MS
Federal
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Sep 17, 2026, 12:54 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Vision Restoration With a Collagen Crosslinked Boston Keratoprosthesis Unit

NCT02863809
View directory record Official record
Conditions
Keratolysis
Interventions
Riboflavin, Dextran, UVA Light Source
Drug · Device
Lead sponsor
Joseph B. Ciolino, MD
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
13
States / cities
Los Angeles, California • Sacramento, California • San Diego, California + 10 more
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Sep 17, 2026, 12:54 AM EDT
Completed Not applicable Interventional

Green Light Therapy As a Non-Pharmacologic Intervention to Decrease Anxiety in Pregnant Women With Opioid Use Disorder

NCT04776616
View directory record Official record
Conditions
Anxiety
Interventions
Exposure to white LED light, Exposure to green LED light
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 25, 2024 · Synced Sep 17, 2026, 12:54 AM EDT
Completed Phase 2Phase 3 Interventional Results available

A Trial of Negative Ion Generation Versus Light-Emitting Diode Phototherapy for Seasonal Affective Disorder (SAD)

NCT00809523
View directory record Official record
Conditions
Seasonal Affective Disorder
Interventions
Negative Ion Generator, Light-emitting Photodiode light treatment device
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
3
States / cities
New Haven, Connecticut • Rockville, Maryland • Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 5, 2013 · Synced Sep 17, 2026, 12:54 AM EDT
Not listed Not applicable Interventional

Pilot Study on the Effects of Low-Level Laser Therapy Treatment for Acute and Persistent Discomfort

NCT04774783
View directory record Official record
Conditions
Chronic Pain, Acute Pain
Interventions
Low-Level Laser Therapy
Device
Lead sponsor
Arkansas Colleges of Health Education
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Fort Smith, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 28, 2021 · Synced Sep 17, 2026, 12:54 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Violet Light for the Suppression of Myopia

NCT06110520
View directory record Official record
Conditions
Myopia, Phototherapy
Interventions
Violet Light Lamp, White Light Lamp
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 12 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 17, 2026, 12:54 AM EDT
Completed Not applicable Interventional Results available

Yoga and Female Concussion

NCT07170488
View directory record Official record
Conditions
Concussion Mild
Interventions
Yoga, Yoga for wait list control
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Sep 17, 2026, 12:54 AM EDT
Completed Not applicable Interventional Results available

LED Therapy for the Treatment of Concussive Brain Injury

NCT02383472
View directory record Official record
Conditions
Brain Concussion
Interventions
MedX Health Console model 1100, MedX Health Console model 1100-placebo
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
11 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 25, 2018 · Synced Sep 17, 2026, 12:54 AM EDT
Recruiting Not applicable Interventional

Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers

NCT05519878
View directory record Official record
Conditions
Bladder Carcinoma, Genitourinary System Neoplasm, Kidney Carcinoma, Prostate Carcinoma
Interventions
Best Practice, Bright White Light Therapy, Occupational Therapy, Questionnaire Administration
Other · Device · Behavioral
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 17, 2026, 12:54 AM EDT
Active, not recruiting Not applicable Interventional

A Simple Intervention to Increase Persistence on PrEP in MSM to Improve Decision Making

NCT06476847
View directory record Official record
Conditions
HIV Infections
Interventions
PrEP persistence
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years and older · Male only
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 17, 2026, 12:54 AM EDT
Completed Not applicable Interventional

A Pilot Test of Mood and Circadian Rhythm Mechanisms Driving Binge Eating

NCT03680989
View directory record Official record
Conditions
Eating Disorder, Binge Eating, Circadian Dysregulation
Interventions
Bright Light Exposure, Natural Light Exposure
Device
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years and older · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Sep 17, 2026, 12:54 AM EDT
Not yet recruiting Not applicable Interventional

Circadian Light Exposure Adjustment for Restfulness

NCT07391852
View directory record Official record
Conditions
Sleep Onset Latency
Interventions
Amber Tinted Glasses, Clear Glasses, Smart Lightbulbs
Device
Lead sponsor
University of Arizona
Other
Eligibility
60 Months to 83 Months
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 17, 2026, 12:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Combined Blue and Red Home-Based Light Therapy on Sleep in Adults With Self-Reported Sleep Difficulties

NCT07465250
View directory record Official record
Conditions
Sleep
Interventions
LED portable light therapy bulb
Other
Lead sponsor
Colorado State University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 17, 2026, 12:54 AM EDT
Completed Not applicable Interventional

Alternative Treatments for Premenstrual Dysphoric Disorder

NCT01799733
View directory record Official record
Conditions
Premenstrual Dysphoric Disorder
Interventions
LWT+AM BWL, EWT+PM BWL
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Sep 17, 2026, 12:54 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Uterine Contractions Under Blue Light

NCT03691740
View directory record Official record
Conditions
Preterm Contractions
Interventions
Ocular light
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 1, 2018 · Synced Sep 17, 2026, 12:54 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Technology and Assessing the Biological Effects of Commercially Available PhotoBioModulation Devices

NCT06403644
View directory record Official record
Conditions
Physiological Wellness
Interventions
NovoTHOR XL Photobiomodulation Full Body Light Bed, ARRC LED Photobiomodulation Full Body Light Bed
Device
Lead sponsor
United States Air Force Research Laboratory
Federal
Eligibility
18 Years to 45 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Beavercreek, Ohio
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 17, 2026, 12:54 AM EDT
Active, not recruiting Phase 2 Interventional

Photobiomodulation for the Prevention of Oral Mucositis

NCT07290413
View directory record Official record
Conditions
Oral Mucositis
Interventions
Photobiomodulation - INTRAORAL, Photobiomodulation - EXTRAORAL, Photobiomodulation - INTRAORAL and EXTRAORAL
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
4 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 17, 2026, 12:54 AM EDT
Recruiting Not applicable Interventional

A Virtual Reality Mindfulness Application for Aggression in Schizophrenia

NCT07434479
View directory record Official record
Conditions
Schizophrenia Disorder, Schizoaffecitve Disorder, Aggression
Interventions
Mindfulness-Based Virtual Reality Intervention
Other
Lead sponsor
Manhattan Psychiatric Center
Other
Eligibility
18 Years to 64 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
New York, New York • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 17, 2026, 12:54 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Efficacy and Safety of Meibomian Gland Dysfunction and Dry Eye With an LED Blue Treatment Device

NCT03788486
View directory record Official record
Conditions
Meibomian Gland Dysfunction
Interventions
2-3 Joule LED blue light device
Device
Lead sponsor
Toyos Clinic
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Germantown, Tennessee • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 17, 2026, 12:54 AM EDT
Completed Not applicable Interventional Results available

30-Minute Light Exposure for the Treatment of Seasonal Affective Disorder

NCT01462305
View directory record Official record
Conditions
Seasonal Affective Disorder
Interventions
goLITE, Control
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 64 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
4
States / cities
Belmont, Massachusetts • Boston, Massachusetts • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2019 · Synced Sep 17, 2026, 12:54 AM EDT
Withdrawn Not applicable Interventional

The Effect of Light Therapy on Post-Surgical Pain

NCT05853731
View directory record Official record
Conditions
Intensive Care Unit, Cardiac Surgery
Interventions
Green light emitting diode, White light emitting diode
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Sep 17, 2026, 12:54 AM EDT