Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 14, 2026, 9:33 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 108 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Lamotrigine (drug) Clear all

Conditions: Healthy Volunteers
Interventions: Xanomeline/Trospium Chloride, Lithium, Valproic Acid, Lamotrigine; Drug
Lead sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 133 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Los Alamitos, California

Conditions: Bipolar Disorder
Interventions: iloperidone; Drug
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Epilepsy, Partial
Interventions: lamotrigine, 300 mg/day, lamotrigine, 250 mg/day; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 13 Years and older
Enrollment: 226 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 67
States / cities: Alabaster, Alabama • Litchfield Park, Arizona • Mesa, Arizona + 56 more

Conditions: Bipolar Disorder
Interventions: Divalproex, Lamotrigine, Lithium; Drug
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 16 Years to 65 Years
Enrollment: 98 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2007
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Mental Disorders
Interventions: Lamotrigine, GI267119; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 19 Years to 55 Years
Enrollment: 96 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Bipolar Disorder
Interventions: lamotrigine; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years and older
Enrollment: 1,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 308
States / cities: Albertville, Alabama • Anniston, Alabama • Birmingham, Alabama + 254 more

Conditions: Bipolar Disorder, Depression, Bipolar
Interventions: Ziprasidone, Placebo; Drug
Lead sponsor: Pfizer's Upjohn has merged with Mylan to form Viatris Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 298 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 60
States / cities: Chandler, Arizona • Litchfield Park, Arizona • Little Rock, Arkansas + 50 more

Conditions: Mental Disorders
Interventions: Ketamine, Lamotrigine, Placebo; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 3 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Neuralgia, Postherpetic
Interventions: Lamictal in the treatment of Post-Herpetic Neuralgia; Drug
Lead sponsor: George Washington University; Other
Eligibility: 18 Years to 85 Years
Timeline: Started 2005
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Adolescent Depression
Interventions: Lamotrigine (drug), Fluoxetine (drug), sertraline (drug); Drug
Lead sponsor: MaineHealth; Other
Eligibility: 13 Years to 18 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Portland, Maine

Conditions: Bipolar Disorder
Interventions: Lamotrigine; Drug
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 10 Years to 20 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Epilepsy
Interventions: Wii Balance Board; Diagnostic Test
Lead sponsor: Erik J. Kobylarz; Other
Eligibility: 16 Years to 55 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Epilepsy
Interventions: lamotrigine; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 1 Month to 24 Months
Enrollment: 197 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2006
U.S. locations: 41
States / cities: Mobile, Alabama • Tucson, Arizona • Jonesboro, Arkansas + 36 more

Conditions: Absence Epilepsy, Ketogenic Dieting, Epilepsy, Absence
Interventions: Modified Atkins Diet, Absence epilepsy medications; Other · Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 3 Years to 12 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Healthy
Interventions: Lamotrigine; Drug
Lead sponsor: Dr. Reddy's Laboratories Limited, India; Industry
Eligibility: 18 Years to 41 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Bipolar Disorder, Cocaine Dependence
Interventions: Lamotrigine, Placebo; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 70 Years
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Brain and Central Nervous System Tumors
Interventions: radiation therapy, Celecoxib; Radiation · Drug
Lead sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 7
States / cities: Tampa, Florida • Atlanta, Georgia • Baltimore, Maryland + 4 more

Conditions: Alcohol Dependence, Post Traumatic Stress Disorder
Interventions: Topiramate, lamotrigine, Placebo; Drug · Other
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Bipolar Disorder
Interventions: Lamotrigine, Fluoxetine; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 65 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Bipolar Disorder, Bipolar Depression
Interventions: citalopram + mood stabilizer, placebo + mood stabilizer; Drug
Lead sponsor: Tufts Medical Center; Other
Eligibility: 18 Years to 64 Years
Enrollment: 119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2014
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Bipolar Disorder
Interventions: lamotrigine; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Seizure, Absence
Interventions: Lamotrigine; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: Up to 12 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 23
States / cities: San Jose, California • Loxahatchee Groves, Florida • Melbourne, Florida + 19 more

Conditions: Cocaine-Related Disorders
Interventions: Lamotrigine; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 59 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1997 – 1999
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Healthy
Interventions: Lamotrigine; Drug
Lead sponsor: Dr. Reddy's Laboratories Limited, India; Industry
Eligibility: 18 Years to 41 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

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A Study to Evaluate the Effects of Lithium, Valproic Acid, and Lamotrigine on the Pharmacokinetics of KarXT and Effects of KarXT on the Pharmacokinetics of Lithium, Valproic Acid, and Lamotrigine in Healthy Participants

Iloperidone in Mixed States of Bipolar Disorder

Conversion To Monotherapy With Lamictal Extended Release Tablets For Treatment Of Partial Epilepsy

Combination Therapy in Dual Diagnosis Bipolar Rapid Cycling

Study to Compare Two Formulations of Lamotrigine in Healthy Subjects

Bipolar Study in Adults at Least 18 Years of Age

Adjunctive Ziprasidone in the Treatment of Bipolar I Depression

The Sustained Effects of Ketamine

Lamictal in the Treatment of Post-Herpetic Neuralgia

Lamotrigine in Treatment Resistant Depression in Adolescents

Lamotrigine Monotherapy in Pediatric Bipolar Disorder

Balance and Anti-Epileptic Drugs

Pediatric Epilepsy Study in Subjects 1-24 Months

Ketogenic Diet for New-Onset Absence Epilepsy

Bioequivalence Study of Lamotrigine 25 mg Chewable Tablets of Dr.Reddy's Under Fed Condition

Lamotrigine add-on Therapy for Bipolar Disorder and Cocaine Dependency

Celecoxib in Patients With Newly Diagnosed GBM Who Are Receiving Anticonvulsant Drugs and Undergoing RT

The Use of Anticonvulsants for Treatment of Patients With Alcohol Dependence and Post Traumatic Stress Disorder

16-week Comparative Effectiveness Trial of Lamotrigine vs. Fluoxetine for Bipolar Depression

Treatment for Bipolar Depression: Acute & Prophylactic Efficacy With Citalopram

Pregnant Women Taking Lamictal for Bipolar Disorder

LAMICTAL (Lamotrigine) For The Treatment Of Absence Seizures

Resperine, Gabapentin, or Lamotrigine for the Treatment of Cocaine Dependence: 2 - 7

Bioequivalence Study of Lamotrigine 25 mg Chewable Tablets of Dr.Reddy's Under Fasting Condition