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ClinicalTrials.gov public records Last synced Oct 1, 2026, 12:28 PM EDT

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Showing 25–48 of 90 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Laparoscopic Hysterectomy Clear all
Not yet recruiting Phase 1Phase 2 Interventional

Long-acting Local Vaginal Cuff Anesthesia Following Hysterectomy

NCT07842159
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Combined Bupivacaine and Exparel, Normal Saline (NS)
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 1, 2026, 12:28 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Oxytocin Receptor Expression in Pregnancy

NCT03907735
View directory record Official record
Conditions
Post-Abortion, Hemorrhage, Obstetric
Interventions
Myometrial tissue sample collection
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 31, 2025 · Synced Oct 1, 2026, 12:28 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Randomized Trial of Wound Infiltration With Extended-release Bupivacaine Before Laparoscopic or Robotic Hysterectomy

NCT02352922
View directory record Official record
Conditions
Pain, Postoperative, Surgical Procedure, Unspecified
Interventions
Liposomal Bupivacaine, Bupivacaine HCl
Drug
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Oct 1, 2020 · Synced Oct 1, 2026, 12:28 PM EDT
Completed Not applicable Interventional Results available

Urinary Retention After Total Laparoscopic Hysterectomy With Immediate Foley Catheter Removal Versus Backfill Void Trial

NCT03141372
View directory record Official record
Conditions
Urinary Retention, Voiding Disorders
Interventions
Void Trial using Foley catheter
Device
Lead sponsor
Sara Farag
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Oct 11, 2018 · Synced Oct 1, 2026, 12:28 PM EDT
Terminated Not applicable Interventional Results available

Pilot Trial of the Robotic Uterine Manipulator

NCT03517228
View directory record Official record
Conditions
Gynecologic Surgery
Interventions
BAUM device
Device
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2024 · Synced Oct 1, 2026, 12:28 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

RCT Superior Hypogastric Block During LH

NCT03283436
View directory record Official record
Conditions
Hysterectomy
Interventions
Bupivacaine Hydrochloride 0.25% Injection Solution
Drug
Lead sponsor
Jon I. Einarsson
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 27, 2020 · Synced Oct 1, 2026, 12:28 PM EDT
Completed No phase listed Observational

Robotic-assisted Laparoscopic Sacrocolpopexy

NCT00581334
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Robotic-assisted laparoscopic sacrocolpopexy, Open sacrocolpopexy
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 23, 2023 · Synced Oct 1, 2026, 12:28 PM EDT
Completed Not applicable Interventional Results available

REstrictive Versus LIbEral Fluid Therapy in Major Abdominal Surgery

NCT02073162
View directory record Official record
Conditions
Major Abdominal Surgery
Interventions
Major Abdominal Surgery
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Oct 1, 2026, 12:28 PM EDT
Completed Phase 1 Interventional Results available

Injection of Local Anesthetic to Trocar Insertion Sites After Laparoscopy

NCT01688596
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Bupivacaine
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Oct 1, 2026, 12:28 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Application of the ICE-T Postoperative Multimodal Pain Regimen to Laparoscopic Hysterectomy

NCT04137770
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Ice pack and ketorolac
Other
Lead sponsor
Mercy Research
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 25, 2024 · Synced Oct 1, 2026, 12:28 PM EDT
Completed Phase 3 Interventional Results available

ESP Block VS TAP in Laparoscopic Hysterectomy

NCT04003987
View directory record Official record
Conditions
Hysterectomy
Interventions
Liposomal bupivacaine, bupivacaine, 0.125%
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 5, 2022 · Synced Oct 1, 2026, 12:28 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Reduced Opioid Prescription After Laparoscopic Hysterectomy

NCT05548582
View directory record Official record
Conditions
Pain, Postoperative, Opioid Misuse, Opioid Use, Pain
Interventions
OxyCODONE 5 mg Oral Tablet, Acetaminophen 500 mg Tab, Ibuprofen 600 mg
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 1, 2026, 12:28 PM EDT
Terminated Not applicable Interventional

Comparison of Laparoscopic to Vaginal Surgical Repair for Uterine Prolapse

NCT01594372
View directory record Official record
Conditions
Uterine Prolapse
Interventions
Laparoscopic supracervical hysterectomy with sacropexy, Vaginal hysterectomy with uterosacral colposuspension
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 4, 2022 · Synced Oct 1, 2026, 12:28 PM EDT
Completed Not applicable Interventional

Postoperative Bladder Testing After Total Laparoscopic Hysterectomy

NCT03126162
View directory record Official record
Conditions
Laparoscopic Hysterectomy, Enhanced Recovery After Surgery
Interventions
InstilIing normal saline into bladder, Removal of foley catheter
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Oct 1, 2026, 12:28 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy

NCT04429022
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Gabapentin, Acetaminophen, Celecoxib, Ketorolac, Paracervical block with ropivacaine, Local anesthetic injection with ropivacaine at abdominal laparoscopic port sites, Hydromorphone, Oxycodone
Drug · Procedure
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
25 Years to 90 Years · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Williamsville, New York
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 1, 2026, 12:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ultravision Visual Clearing System in Laparoscopic Hysterectomy and Myomectomy

NCT03634306
View directory record Official record
Conditions
Pain, Hysterectomy, Myomectomy
Interventions
Ultravision System, Laparoscopic Hysterectomy
Device · Procedure
Lead sponsor
Mercy Research
Other
Eligibility
21 Years and older · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 1, 2026, 12:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Outcomes on Abdominal Versus Vaginal Morcellation At Time of Hysterectomy

NCT04434066
View directory record Official record
Conditions
Abnormal Uterine Bleeding, Uterine Bleeding, Fibroid Uterus, Surgery
Interventions
Total Laparoscopic Hysterectomy
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 8, 2024 · Synced Oct 1, 2026, 12:28 PM EDT
Recruiting No phase listed Observational

Outpatient Visits Versus Telehealth for Postoperative Care After Minimally Invasive Gynecologic Surgery

NCT07420114
View directory record Official record
Conditions
to Determine Whether Patient Satisfaction With Postoperative Telehealth Follow-up is Non-inferior to In-person Clinic Visits
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Chicago, Illinois • Hinsdale, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 1, 2026, 12:28 PM EDT
Recruiting Phase 4 Interventional

Preoperative Acetazolamide

NCT07101250
View directory record Official record
Conditions
Post Operative Pain, Laparoscopic Hysterectomy, Referred Pain
Interventions
Acetazolamide 500 MG Extended Release Oral Capsule, Placebo
Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 1, 2026, 12:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prophylactic Modified McCall Culdoplasty During Total Laparoscopic Hysterectomy

NCT01840176
View directory record Official record
Conditions
Vaginal Vault Prolapse, Sexual Function
Interventions
McCall culdoplasty
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 1, 2026, 12:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology

NCT02853591
View directory record Official record
Conditions
Pain, Pneumoperitoneum, Inflammation, Quality of Life
Interventions
Pneumoinsufflator mode and setting
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Mar 8, 2023 · Synced Oct 1, 2026, 12:28 PM EDT
Recruiting No phase listed Observational

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

NCT05051722
View directory record Official record
Conditions
Endometrial Cancer, Cervical Cancer, Atypical Endometrial Hyperplasia, Cervical Dysplasia, Adnexal Mass, Ovarian Cancer
Interventions
Vaginal Fluid Collection, Blood Collection
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
3,110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
25
States / cities
Phoenix, Arizona • Jacksonville, Florida • Miami, Florida + 21 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 1, 2026, 12:28 PM EDT
Completed Phase 3 Interventional

Pilot: Intraoperative TAP Block and Post-operative Pain Control for Minimally Invasive Hysterectomy for Endometrial Cancer

NCT05763667
View directory record Official record
Conditions
Post Operative Pain, Gynecologic Cancer
Interventions
Liposomal bupivacaine, Bupivacain
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 1, 2026, 12:28 PM EDT
Recruiting Phase 3 Interventional

Sentinel Node Biopsy in Endometrial Cancer

NCT04073706
View directory record Official record
Conditions
Endometrial Cancer Stage I, Sentinel Lymph Node, Surgery
Interventions
TH BSO with SNB Note: If participants (≤45yo), Grade 1 endometrial adenocarcinoma with myometrial invasion <50%, wish to retain their ovaries a BSO may be omitted, TH BSO without retroperitoneal node dissection Note: If participants (≤45yo), Grade 1 endometrial adenocarcinoma with myometrial invasion <50%, wish to retain their ovaries a BSO may be omitted
Procedure
Lead sponsor
Queensland Centre for Gynaecological Cancer
Government
Eligibility
18 Years and older · Female only
Enrollment
760 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2031
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 1, 2026, 12:28 PM EDT