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ClinicalTrials.gov public records Last synced Oct 10, 2026, 10:51 AM EDT

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Showing 25–48 of 87 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Laparoscopic Roux-en-Y gastric bypass Clear all
Completed Not applicable Interventional Results available

Laparoscopic Gastric Bypass vs LAP-BAND for Treatment of Morbid Obesity

NCT00247377
View directory record Official record
Conditions
Morbid Obesity
Interventions
Gastric bypass surgery, Lap-Band
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 60 Years
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Oct 10, 2026, 10:51 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Perioperative Ketamine for Pain With Gastric Bypass

NCT03448068
View directory record Official record
Conditions
Laparoscopic Gastric Bypass Surgery, Ketamine
Interventions
Ketamine, Standard therapy
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 69 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Oct 10, 2026, 10:51 AM EDT
Completed Not applicable Interventional Results available

The Effect of Pre-Operative Transversus Abdominis Plane (TAP) Block in the Post Operative Opioid Consumption in Morbid Obese Patients Undergoing Laparoscopic Gastric Bypass Surgery: A Prospective,Randomized, Blinded Study

NCT01075087
View directory record Official record
Conditions
Pain, Obesity, Surgery
Interventions
Placebo, (study group) will receive a bilateral TAP block using 20 cc of 0.5% ropivacaine on each side.
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 26, 2014 · Synced Oct 10, 2026, 10:51 AM EDT
Active, not recruiting No phase listed Observational

Biological Sample Repository for Gastrointestinal Disorders

NCT05874726
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder, Overweight and Obesity, Overweight, Overweight or Obesity, Diabetes Type 2, Diabetes Mellitus, Diabetes Mellitus, Type 2, Hypertension, Hyperlipidemias, Sleep Apnea, GERD, Gastroesophageal Reflux, Musculoskeletal Pain Disorder, Cancer
Interventions
Blood Collection, Urine Collection, Tissue Sample Collection
Diagnostic Test
Lead sponsor
Pichamol Jirapinyo, MD, MPH
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 10, 2026, 10:51 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Study of Proton Pump Inhibitors (PPI) to Prevent Strictures After Gastric Bypass Surgery

NCT00361985
View directory record Official record
Conditions
Anastomotic Stricture, Morbid Obesity
Interventions
Esomeprazole
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 1, 2016 · Synced Oct 10, 2026, 10:51 AM EDT
Active, not recruiting Not applicable Interventional

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes

NCT01047735
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
Procedure · Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
25 Years to 55 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 10, 2026, 10:51 AM EDT
Completed Not applicable Interventional

Impact of GBS on CVD in Type 2 Diabetes Mellitus

NCT00787670
View directory record Official record
Conditions
Obesity, Type 2 Diabetes Mellitus
Interventions
Diabetes Support and Education, gastric bypass surgery, Tissue Control Group
Other · Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years to 60 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2013 · Synced Oct 10, 2026, 10:51 AM EDT
Active, not recruiting No phase listed Observational

Comparison of Body Composition Changes With Weight Loss Interventions

NCT07115069
View directory record Official record
Conditions
Obesity
Interventions
GLP-1 receptor agonist, Gastric Bypass Surgery (laparoscopic), Gastric Bypass Surgery (robotic)
Drug · Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
60 participants
Timeline
2025 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 10, 2026, 10:51 AM EDT
Completed Phase 2Phase 3 Interventional

Improving Diabetes Through Lifestyle and Surgery

NCT01667783
View directory record Official record
Conditions
Obesity, Type 2 Diabetes
Interventions
Gastric Banding, Medical Weight Loss, Gastric Bypass
Procedure · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 64 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 12, 2024 · Synced Oct 10, 2026, 10:51 AM EDT
Completed No phase listed Observational

Adding Malabsorption for Failed Gastric Bypass

NCT01040481
View directory record Official record
Conditions
Clinically Severe Obesity, Obesity Recidivism, Inadequate Initial Weight Loss, Poor Weight Loss, Persistent Obesity, Refractory Obesity, Intractable Obesity
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Dec 29, 2009 · Synced Oct 10, 2026, 10:51 AM EDT
Completed No phase listed Observational

Alliance of Randomized Trials of Medicine vs Metabolic Surgery in Type 2 Diabetes

NCT02328599
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Bariatric surgery involving Roux-en-Y gastric bypass, Bariatric surgery involving Laparoscopic adjustable gastric banding, Bariatric surgery involving Laparoscopic sleeve gastrectomy
Procedure
Lead sponsor
Ali Aminian
Other
Eligibility
20 Years to 65 Years
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
4
States / cities
Boston, Massachusetts • Cleveland, Ohio • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 10, 2026, 10:51 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Fat Taste Sensory Study

NCT03540693
View directory record Official record
Conditions
Bariatric Surgery Candidate, Bariatric Surgical Procedure
Interventions
RYGB, SG, LAGB
Procedure
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 64 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Oct 10, 2026, 10:51 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effect of Liposomal Bupivacaine on Post Operative Pain and Narcotic Use After Bariatric Surgery

NCT03196505
View directory record Official record
Conditions
Bariatric Surgery Candidate, Pain, Postoperative
Interventions
Exparel 266 MG Per 20 ML Injection, Bupivacaine
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
231 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Nov 25, 2020 · Synced Oct 10, 2026, 10:51 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Alcohol and Bariatric Surgery

NCT02766322
View directory record Official record
Conditions
Obesity
Interventions
Oral Alcohol challenge test Alcohol visit first, Oral Alcohol challenge test Placebo visit first, Intravenous Alcohol Challenge Test (Clamp), Intravenous Alcohol Self-administration Test
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years to 64 Years · Female only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 10, 2026, 10:51 AM EDT
Completed No phase listed Observational

Laparoscopic Revision of Jejunoileal Bypass to Gastric Bypass

NCT01040533
View directory record Official record
Conditions
Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass, Nutritional Complications After Jejunoileal Bypass, Obesity Recidivism, Inadequate Initial Weight Loss, Intestinal Malabsorptive Syndrome, Protein Malnutrition
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Dec 29, 2009 · Synced Oct 10, 2026, 10:51 AM EDT
Completed No phase listed Observational

Glucose Homeostasis Pre and Post Bariatric Surgery

NCT00981500
View directory record Official record
Conditions
Morbid Obesity
Interventions
gastric bypass, gastric banding, sleeve gastrectomy
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
20 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 10, 2018 · Synced Oct 10, 2026, 10:51 AM EDT
Completed No phase listed Observational

Laparoscopy-assisted ERCP in Patients With Altered Gastric Anatome

NCT01620632
View directory record Official record
Conditions
Biliary Disease, Pancreas Disease
Interventions
Laparoscopy assisted ERCP
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 9, 2018 · Synced Oct 10, 2026, 10:51 AM EDT
Completed No phase listed Observational Results available

Taste Perception Pre and Post Bariatric Surgery

NCT01536197
View directory record Official record
Conditions
Morbid Obesity
Interventions
Gastric bypass, Gastric banding, Sleeve gastrectomy
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
20 Years to 70 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 18, 2017 · Synced Oct 10, 2026, 10:51 AM EDT
Terminated Not applicable Interventional

Laparoscopic Revision of an Enlarged Gastric Outlet After Gastric Bypass

NCT01116284
View directory record Official record
Conditions
Morbid Obesity
Interventions
Revision of gastric bypass
Procedure
Lead sponsor
Baystate Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 12, 2016 · Synced Oct 10, 2026, 10:51 AM EDT
Completed Not applicable Interventional

Effect of Bariatric Surgery on Mechanisms of Type 2 Diabetes

NCT01278823
View directory record Official record
Conditions
Obesity, Type 2 Diabetes
Interventions
laparoscopic roux en y gastric bypass operation, medical management
Procedure · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 60 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 11, 2019 · Synced Oct 10, 2026, 10:51 AM EDT
Completed No phase listed Observational

Comparison Between Gastric Band, Laparoscopic Sleeve Gastrectomy, Gastric Bypass Surgeries

NCT02004561
View directory record Official record
Conditions
Obese Adolescents
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
14 Years to 19 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 10, 2026, 10:51 AM EDT
Completed Not applicable Interventional

Calorie Reduction Or Surgery: Seeking Remission for Obesity And Diabetes

NCT01295229
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
laparoscopic Roux-en-Y gastric bypass (RYGB) procedure, Lifestyle Intervention
Procedure · Behavioral
Lead sponsor
University of Washington
Other
Eligibility
25 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 31, 2016 · Synced Oct 10, 2026, 10:51 AM EDT
Completed No phase listed Observational

Retrospective Comparison of Lap and Robotic-Assisted RYGB and SG

NCT04329780
View directory record Official record
Conditions
Bariatric Surgery Candidate
Interventions
Not listed
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years and older
Enrollment
1,872 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 13, 2025 · Synced Oct 10, 2026, 10:51 AM EDT
Not listed Not applicable Interventional

Efficacy of IV Acetaminophen in Acute Post-Operative Pain Control in Laparoscopic Roux-en-Y Gastric Bypass Surgery (LRYGBP) Patients

NCT01460667
View directory record Official record
Conditions
Morbid Obesity
Interventions
IV acetaminophen, IV normal saline
Drug
Lead sponsor
McLaren Regional Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 27, 2011 · Synced Oct 10, 2026, 10:51 AM EDT