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Showing 1–24 of 66 matching trials from the live ClinicalTrials.gov search.
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Recruiting Phase 2 Interventional

A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant

NCT05675930
View directory record Official record
Conditions
Graft-Versus-Host Disease, GVHD, Undefined
Interventions
Photobiomodulation Therapy, Placebo sham device
Device · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
4 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
9
States / cities
Bethesda, Maryland • Basking Ridge, New Jersey • Middletown, New Jersey + 6 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 3, 2026, 2:37 PM EDT
Completed Not applicable Interventional Results available

Randomized Pilot Study of Treatment for BCC Using the Multiplex 595/1064 nm Laser

NCT02270645
View directory record Official record
Conditions
Nodular Basal Cell Carcinoma, Superficial Basal Cell Carcinoma
Interventions
595/1064 multiplex laser
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 1, 2018 · Synced Sep 3, 2026, 2:37 PM EDT
Completed Phase 3 Interventional Results available

Systemic Chemotherapy and Subtenon Carboplatin, and Local Ophthalmic Therapy in Children With Intraocular Retinoblastoma

NCT00072384
View directory record Official record
Conditions
Intraocular Retinoblastoma
Interventions
liposomal vincristine sulfate, cryosurgery, laser surgery, carboplatin, etoposide, filgrastim
Drug · Procedure · Biological
Lead sponsor
Children's Oncology Group
Network
Eligibility
Up to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2021
U.S. locations
11
States / cities
Arcadia, California • Downey, California • Los Angeles, California + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2021 · Synced Sep 3, 2026, 2:37 PM EDT
Terminated Not applicable Interventional Results available

Comparing Acular LS and Pred Forte in Reducing Post-selective Laser Trabeculoplasty Anterior Chamber Flare and Cells

NCT00478036
View directory record Official record
Conditions
Open Angle Glaucoma
Interventions
Acular LS, Pred Forte, Refresh Tears
Drug · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Sep 3, 2026, 2:37 PM EDT
Completed Phase 3 Interventional Results available

Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular Hypertension

NCT02507687
View directory record Official record
Conditions
Glaucoma, Open-Angle, Ocular Hypertension
Interventions
Bimatoprost SR, Sham Bimatoprost SR, Selective Laser Trabeculoplasty, Sham Selective Laser Trabeculoplasty
Drug · Procedure
Lead sponsor
AbbVie
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
51
States / cities
Dothan, Alabama • Glendale, Arizona • Phoenix, Arizona + 43 more
Source: ClinicalTrials.gov public record
Updated May 9, 2024 · Synced Sep 3, 2026, 2:37 PM EDT
Terminated Not applicable Interventional

Trial of Photodynamic Therapy Versus Argon Plasma Coagulation for Lung Cancer With Endobronchial Obstruction

NCT03564054
View directory record Official record
Conditions
Non Small Cell Lung Cancer
Interventions
Photodynamic Therapy, Argon Plasma Coagulation
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Sep 3, 2026, 2:37 PM EDT
Completed Phase 1 Interventional

Imiquimod and Laser Therapy With or Without a Green Dye in Treating Patients With Stage III or Stage IV Melanoma That Has Spread to Other Parts of the Skin

NCT00453050
View directory record Official record
Conditions
Melanoma (Skin), Metastatic Cancer
Interventions
imiquimod, indocyanine green solution, flow cytometry, immunologic technique, laboratory biomarker analysis
Drug · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 5, 2015 · Synced Sep 3, 2026, 2:37 PM EDT
Recruiting Phase 1Phase 2 Interventional

Treating Basal and Squamous Cell Carcinomas With Fractional Laser and Tirbanibulin Ointment

NCT07010692
View directory record Official record
Conditions
Keratinocyte Carcinoma, Basal Cell Carcinomas, Squamous Cell Carcinoma, Skin Cancer
Interventions
Tirbanibulin ointment 1%, non-ablative fractional laser
Drug · Device
Lead sponsor
Bruce Robinson, MD
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 3, 2026, 2:37 PM EDT
Completed Not applicable Interventional Results available

Long-pulsed 1064 nm Nd:YAG Laser Treatment of Basal Cell Carcinoma

NCT02662244
View directory record Official record
Conditions
Basal Cell Carcinoma
Interventions
Nd:YAG laser
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 5, 2019 · Synced Sep 3, 2026, 2:37 PM EDT
Completed Phase 1 Interventional

Stem Cell Heart Injections During Laser Revascularization Surgery for Treatment of Chronic Ischemic Heart Disease

NCT03043742
View directory record Official record
Conditions
Chronic Ischemic Heart Disease
Interventions
Bone Marrow Derived Autologous CD133+ Selected Cell Product
Drug
Lead sponsor
Michael Sekela
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 10, 2020 · Synced Sep 3, 2026, 2:37 PM EDT
Completed No phase listed Observational

Comparative Effectiveness of Psoriasis Treatments on Systemic Inflammation

NCT02330380
View directory record Official record
Conditions
Psoriasis, Inflammation
Interventions
Methotrexate, Ustekinumab, Etanercept, Adalimumab, Acitretin, UVB Excimer Laser, Narrowband UVB
Drug · Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 3, 2026, 2:37 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma

NCT04744935
View directory record Official record
Conditions
Basal Cell Carcinoma, Superficial Basal Cell Carcinoma, Nodular Basal Cell Carcinoma
Interventions
1064 nm long-pulse Nd:YAG laser
Device
Lead sponsor
Christopher Zachary
Other
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 3, 2026, 2:37 PM EDT
Terminated Not applicable Interventional

Augmenting Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder With Low-Level Light Therapy

NCT02898233
View directory record Official record
Conditions
Depression
Interventions
Deprexis, Active low-level light therapy, Sham low-level light therapy
Other · Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Sep 3, 2026, 2:37 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Laser Cell Therapy for Knee Cartilage Repair

NCT04001361
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Laser Cell Therapy
Procedure
Lead sponsor
Endocellutions
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Steubenville, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 27, 2019 · Synced Sep 3, 2026, 2:37 PM EDT
Terminated Not applicable Interventional Results available

Mechanistically-based Optimization of UV Radiation Therapy in Psoriasis

NCT00470392
View directory record Official record
Conditions
Psoriasis
Interventions
Imiquimod, Clobetasol
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 4, 2016 · Synced Sep 3, 2026, 2:37 PM EDT
Terminated Not applicable Interventional

OCT-guided LALAK in Children

NCT01579643
View directory record Official record
Conditions
Corneal Opacity
Interventions
OCT guided laser-assisted lamellar anterior keratoplasty (LALAK), Penetrating Keratoplasty (KP)
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
1 Month to 18 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2018 · Synced Sep 3, 2026, 2:37 PM EDT
Not listed Not applicable Interventional

Oxygenating the Brain With Laser Therapy

NCT05354895
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Transcranial infrared laser stimulation
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 78 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 1, 2022 · Synced Sep 3, 2026, 2:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Laser Treatment of Basal Cell Carcinoma

NCT04936932
View directory record Official record
Conditions
Basal Cell Carcinoma
Interventions
1064 nm long-pulse Nd:YAG laser
Device
Lead sponsor
Sciton
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Spring Hill, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Sep 3, 2026, 2:37 PM EDT
Terminated Not applicable Interventional Results available

Photodynamic Therapy Using Porfimer Sodium in Treating Patients With Recurrent Mouth or Throat Dysplasia or Recurrent In Situ Cancer or Stage I Cancer of the Mouth or Throat

NCT00530088
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
porfimer sodium, Photdynamic Therapy (PDT)
Drug
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2010
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jul 3, 2014 · Synced Sep 3, 2026, 2:37 PM EDT
Completed Phase 1 Interventional Results available

Feasibility Study of Using Navigational Bronchoscopy to Perform PDT-Photofrin® in Unresectable Peripheral Lung Cancer

NCT02916745
View directory record Official record
Conditions
Non-small Cell Lung Cancer (NSCLC), Lung Metastasis
Interventions
Porfimer sodium, Fiber optic
Drug · Device
Lead sponsor
Concordia Laboratories Inc.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
6
States / cities
Gainesville, Florida • Atlanta, Georgia • Elk Grove Village, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Sep 3, 2026, 2:37 PM EDT
Active, not recruiting Phase 2 Interventional

Photobiomodulation for the Prevention of Oral Mucositis

NCT07290413
View directory record Official record
Conditions
Oral Mucositis
Interventions
Photobiomodulation - INTRAORAL, Photobiomodulation - EXTRAORAL, Photobiomodulation - INTRAORAL and EXTRAORAL
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
4 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 3, 2026, 2:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining the Differential Effects of Photobiomodulation on Sleep and Performance

NCT05116605
View directory record Official record
Conditions
Sleep Quality
Interventions
Photobiomodulation (PBM)
Other
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Sep 3, 2026, 2:37 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

LED Device for Non-Invasive Lipolysis

NCT03171051
View directory record Official record
Conditions
Lipolysis
Interventions
950 nm LED Device, 1050nm Diode Laser Device
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 8, 2020 · Synced Sep 3, 2026, 2:37 PM EDT
Terminated Phase 4 Interventional Results available

RECELL to Promote Healing Following Carbon Dioxide (CO2) Laser Treatment in Cosmetic Patients

NCT05386368
View directory record Official record
Conditions
Carbon Dioxide Laser, Photoaging
Interventions
ReCell
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 99 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Sep 3, 2026, 2:37 PM EDT