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ClinicalTrials.gov public records Last synced Oct 12, 2026, 11:33 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 452 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Laser Intervention Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

In Vivo Liquid Biopsy of Melanoma (Cytophone)

NCT06488365
View directory record Official record
Conditions
Melanoma, Circulating Tumor Cells, Metastatic Melanoma, Diagnosis
Interventions
Cytophone
Device
Lead sponsor
Cytoastra
Industry
Eligibility
18 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 12, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Prospective, Contralateral, Eye to Eye Comparison of SMILE Surgery to LASIK Surgery

NCT03067077
View directory record Official record
Conditions
Myopia
Interventions
SMILE, LASIK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 59 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Oct 12, 2026, 11:33 PM EDT
Completed Phase 1 Interventional

MRI-Guided Laser Surgery and Doxorubicin Hydrochloride in Treating Patients With Recurrent Glioblastoma Multiforme

NCT01851733
View directory record Official record
Conditions
Glioblastoma
Interventions
MRI-guided Laser Heat Ablation (MLA), Doxorubicin, Blood draw - dendritic cells, Dynamic Susceptibility Contrast Magnetic Resonance Imaging
Device · Drug · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 27, 2021 · Synced Oct 12, 2026, 11:33 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Emsella for Reducing tSUI After HOLEP

NCT07580404
View directory record Official record
Conditions
Benign Prostatic Hyperplasia, Enlarged Prostate With Lower Urinary Tract Symptoms, Enlarged Prostate (BPH)
Interventions
Emsella chair
Device
Lead sponsor
Northwestern University
Other
Eligibility
50 Years to 80 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 12, 2026, 11:33 PM EDT
Completed Not applicable Interventional

Healing of the Esophageal Mucosa After RFA of Barrett's Esophagus

NCT02688114
View directory record Official record
Conditions
Barrett Esophagus
Interventions
Baseline surveillance endoscopy, Radiofrequency ablation, Follow up endoscopy 1, Follow up endoscopy 2, Follow up endoscopy 3
Procedure
Lead sponsor
Dallas VA Medical Center
Federal
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 11, 2023 · Synced Oct 12, 2026, 11:33 PM EDT
Completed Early Phase 1 Interventional

Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas

NCT02970448
View directory record Official record
Conditions
High Grade Glioma
Interventions
LITT, Radiation therapy, Temozolomide
Procedure · Radiation · Drug
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 12, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Excimer Light Treatment for Idiopathic Guttate Hypomelanosis: A Pilot Study

NCT01956435
View directory record Official record
Conditions
Idiopathic Guttate Hypomelanosis
Interventions
Excimer Light Treatment
Device
Lead sponsor
Seton Healthcare Family
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2017 · Synced Oct 12, 2026, 11:33 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

AVAVA MIRIA General Use

NCT06868615
View directory record Official record
Conditions
Acne, Acne Scars - Mixed Atrophic and Hypertrophic, Scars, Wrinkle, Pigment; Lesion, Skin Texture Disorder
Interventions
AVAVA
Device
Lead sponsor
AVAVA, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 12, 2026, 11:33 PM EDT
Completed Not applicable Interventional

Confocal Endomicroscopy of Pancreatic InVivo

NCT01035008
View directory record Official record
Conditions
Pancreatic Cysts
Interventions
Endoscopic Ultrasound (EUS)
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 23, 2012 · Synced Oct 12, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing the Pain Experience Between Patients Who Have and Who Have Not Undergone Dermatologic Procedures

NCT01285947
View directory record Official record
Conditions
Pain
Interventions
Thermage, Needle Application, VBeam Laser, Ulthera
Device · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 6, 2021 · Synced Oct 12, 2026, 11:33 PM EDT
Terminated Not applicable Interventional Results available

Effect of the Erchonia® HLS™ for the Relief of Tinnitus Symptoms

NCT05091060
View directory record Official record
Conditions
Tinnitus
Interventions
Erchonia HLS
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Walnut Creek, California
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Oct 12, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MonaLisa Touch Randomized Double-Blind Placebo Controlled Study

NCT03331328
View directory record Official record
Conditions
Genitourinary Syndrome of Menopause
Interventions
MonaLisa Touch
Device
Lead sponsor
Michigan Institution of Women's Health PC
Other
Eligibility
Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dearborn, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 12, 2026, 11:33 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Application of Indocyanine Green Angiography for Closed Operative Calcaneus Fractures

NCT01693484
View directory record Official record
Conditions
Fractures, Comminuted, Surgical Wound Dehiscence, Necrosis
Interventions
ICG (Indocyanine Green)
Drug
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Oct 12, 2026, 11:33 PM EDT
Recruiting Phase 2 Interventional

Laser Interstitial Thermal Therapy (LITT) or Surgery and Adjuvant Reirradiation for Recurrent Brain Metastases (LaSAR BeaM)

NCT07053033
View directory record Official record
Conditions
Brain Metastases
Interventions
Surgery, LITT
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 12, 2026, 11:33 PM EDT
Not yet recruiting Not applicable Interventional

Prospective Multi-center Study Comparing Pulsed Tm:YAG Laser to Pulse Modulated Holmium Laser in the Treatment of Nephrolithiasis With FANS Access Sheaths

NCT07516106
View directory record Official record
Conditions
Kidney Stone
Interventions
Moses Holmium:YAG laser, Thulium:YAG laser
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Phoenix, Arizona • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 12, 2026, 11:33 PM EDT
Withdrawn No phase listed Observational

Intraoperative Optical Imaging of Brain Function

NCT00632437
View directory record Official record
Conditions
Brain Tumor
Interventions
Speckle-Contrast Imaging
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2012 · Synced Oct 12, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

IntraLase vs Hansatome Flaps in LASIK

NCT00691431
View directory record Official record
Conditions
Myopia
Interventions
LASIK
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2011 · Synced Oct 12, 2026, 11:33 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Hyperopia Correction Using the NTK Optimal Keratoplasty (Opti-K) System

NCT01028937
View directory record Official record
Conditions
Hyperopia
Interventions
Optimal Keratoplasty
Device
Lead sponsor
NTK Enterprises, Inc.
Industry
Eligibility
40 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Oct 12, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sequential vs. Standard Laser Treatment of Twin-twin Transfusion Syndrome

NCT02122328
View directory record Official record
Conditions
Twin Twin Transfusion Syndrome
Interventions
Sequential laser photocoagulation of communicating vessels., Selective laser photocoagulation of communicating vessels
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
16 Years to 55 Years · Female only
Enrollment
642 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 20, 2025 · Synced Oct 12, 2026, 11:33 PM EDT
Not listed Not applicable Interventional

Effectiveness of Laser Hair Removal in Pilonidal Disease

NCT03276065
View directory record Official record
Conditions
Pilonidal Disease
Interventions
Laser depilation, Standard of care hair depilation
Device · Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
11 Years to 21 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Oct 12, 2026, 11:33 PM EDT
Not listed Not applicable Interventional

Oxygenating the Brain With Laser Therapy

NCT05354895
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Transcranial infrared laser stimulation
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 78 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Oct 12, 2026, 11:33 PM EDT
Completed No phase listed Observational

Bowel Dysfunction and HoLEP Outcomes

NCT06688500
View directory record Official record
Conditions
Urologic Injuries
Interventions
Bowel function post Holmium Laser Enucleation of the Prostate
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 89 Years · Male only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 12, 2026, 11:33 PM EDT
Terminated Not applicable Interventional Results available

SLlt Stent II Lacrimal Stent for the Treatment of Nasolacrimal Duct Obstruction

NCT03705000
View directory record Official record
Conditions
Epiphora, Dacryocystorhinostomy
Interventions
Slit Stent II, BIKA for DCR
Device
Lead sponsor
Thomas Gardner
Other
Eligibility
22 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 12, 2026, 11:33 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Laser Enucleation of Prostate (LEP) Versus Transurethral Resection of Prostate (TURP)

NCT03062111
View directory record Official record
Conditions
Benign Prostatic Hyperplasia
Interventions
ProTouch Laser Enucleation of Prostate (LEP), Transurethral Resection of Prostate (TURP)
Procedure
Lead sponsor
Boston University
Other
Eligibility
50 Years and older · Male only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Oct 12, 2026, 11:33 PM EDT