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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Laser Lithotripsy Clear all
Completed Not applicable Interventional Results available

Utilizing Holmium Laser for FURS Renal Stone Lithotripsy Comparing Stone Breaking vs. Stone Dusting Settings

NCT02683993
View directory record Official record
Conditions
Stone Clearance
Interventions
Lumenis Pulse 120H holmium laser system and 200 DFL ball tip fiber
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 9, 2026, 1:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acoustic Enhancer Research on Laser Lithotripsy (AEROLITH)

NCT04563039
View directory record Official record
Conditions
Urinary Stones
Interventions
Ureteroscopy Laser Lithotripsy (URS-LL) with Acoustic Enhancer, Standard Ureteroscopic Laser Lithotripsy
Device
Lead sponsor
Avvio Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
23
States / cities
Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 20 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Sep 9, 2026, 1:58 AM EDT
Completed Not applicable Interventional Results available

A Comparison of Ureteroscopic Treatment of Nephrolithiasis With and Without Moses Technology

NCT04505956
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Holmium laser lithotripsy with Moses Technology, Holmium laser lithotripsy without Moses Technology
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
6
States / cities
Phoenix, Arizona • San Diego, California • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Sep 9, 2026, 1:58 AM EDT
Active, not recruiting Not applicable Interventional

Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE)

NCT06181240
View directory record Official record
Conditions
Coronary Artery Disease, Coronary Artery Calcification
Interventions
Intravascular lithotripsy
Device
Lead sponsor
Bolt Medical
Industry
Eligibility
18 Years and older
Enrollment
426 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
31
States / cities
La Jolla, California • Los Angeles, California • Riverside, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 9, 2026, 1:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Performance of the SOLTIVE Laser System for Laser Lithotripsy in Kidney or Ureteral Stones

NCT04556201
View directory record Official record
Conditions
Kidney Stone, Ureteral Stone
Interventions
SOLTIVE™ Premium SuperPulsed Laser Fiber System
Device
Lead sponsor
Olympus Corporation of the Americas
Industry
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
5
States / cities
Phoenix, Arizona • Loma Linda, California • Kansas City, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Sep 9, 2026, 1:58 AM EDT
Active, not recruiting No phase listed Observational

Stone and Laser Therapies Post-Market Study (SALT)

NCT06982235
View directory record Official record
Conditions
Benign Prostate Hypertrophy(BPH), Renal Calculi, Ureteral Stones, Kidney Stones, Calculi, Urinary, Urinary Tract Procedure
Interventions
Ureteroscope system, Laser system
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
5
States / cities
Phoenix, Arizona • Miami, Florida • Tampa, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 9, 2026, 1:58 AM EDT
Terminated Not applicable Interventional

Use of Antiretropulsion Device in Laser Lithotripsy

NCT00859170
View directory record Official record
Conditions
Kidney Stones
Interventions
Accordion device
Device
Lead sponsor
Percutaneous Systems, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
3
States / cities
Downey, California • New York, New York • Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2010 · Synced Sep 9, 2026, 1:58 AM EDT
Completed Not applicable Interventional Results available

Comparison of Laser Lithotripsy With and Without Steerable Ureteroscopic Renal Evacuation (SURE)

NCT04519294
View directory record Official record
Conditions
Kidney Stone, Renal Stone, Urolithiasis
Interventions
SURE, Standard Ureteroscopy (Basketing)
Device
Lead sponsor
Calyxo, Inc.
Industry
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
11
States / cities
Phoenix, Arizona • Tucson, Arizona • Baltimore, Maryland + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 9, 2026, 1:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

SP TLF Versus Ho:YAG Laser

NCT05048706
View directory record Official record
Conditions
Urinary Calculi
Interventions
Laser lithotripsy (SP TLF), Laser lithotripsy (Ho:YAG)
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced Sep 9, 2026, 1:58 AM EDT
Completed Phase 4 Interventional Results available

Moses vs. Thulium Laser Study

NCT04963062
View directory record Official record
Conditions
Urinary Tract Stone
Interventions
Holmium laser with Moses lasers, Holmium laser with thulium lasers
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 89 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 9, 2026, 1:58 AM EDT
Completed Not applicable Interventional

Electrohydraulic Versus Laser Lithotripsy for Treatment of Difficult to Remove Biliary Stones

NCT01571271
View directory record Official record
Conditions
Gall Stones
Interventions
Laser Lithotripsy, Electrohydraulic Lithotripsy
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Sep 9, 2026, 1:58 AM EDT
Completed Not applicable Interventional

Quality of Life in Kidney Stone Patients Undergoing Surgery

NCT02625051
View directory record Official record
Conditions
Kidney Calculi, Quality of Life
Interventions
Ureteroscopy, Percutaneous nephrolithotomy
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Sep 9, 2026, 1:58 AM EDT
Completed Not applicable Interventional Results available

Trial Assessing Renal Damage During Ureteroscopy

NCT05350423
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Thulium Fibre Laser, Holmium:Yttrium-Aluminum-Garnet
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Sep 9, 2026, 1:58 AM EDT
Completed No phase listed Observational Results available

Flexiva Pulse Registry

NCT05027971
View directory record Official record
Conditions
Urinary Calculi, Benign Prostatic Hyperplasia
Interventions
Flexiva Pulse High Power Single-Use Laser Fibers
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
4
States / cities
Phoenix, Arizona • Miami, Florida • Orlando, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 9, 2026, 1:58 AM EDT
Withdrawn Not applicable Interventional

Long Pulse Versus Short Pulse Laser Dusting for Renal Stones

NCT03608098
View directory record Official record
Conditions
Kidney Stone, Ureter Stone, Renal Stone
Interventions
Short Pulse Duration, Long Pulse Duration
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 2, 2019 · Synced Sep 9, 2026, 1:58 AM EDT
Not yet recruiting Not applicable Interventional

Prospective Multi-center Study Comparing Pulsed Tm:YAG Laser to Pulse Modulated Holmium Laser in the Treatment of Nephrolithiasis With FANS Access Sheaths

NCT07516106
View directory record Official record
Conditions
Kidney Stone
Interventions
Moses Holmium:YAG laser, Thulium:YAG laser
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Phoenix, Arizona • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 9, 2026, 1:58 AM EDT
Not listed Not applicable Interventional

ESWL vs. Pancreatoscopy-guided Lithotripsy for Painful Chronic Calcific Pancreatitis

NCT04115826
View directory record Official record
Conditions
Pancreatitis, Chronic
Interventions
Per-oral Pancreatoscopy-guided Lithotripsy, Extracorporeal Shock-Wave Lithotripsy
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Sep 9, 2026, 1:58 AM EDT
Terminated Not applicable Interventional Results available

MOSES Lithotripsy Technology Applied to Stone Fragmentation During Ureteroscopy

NCT03995758
View directory record Official record
Conditions
Kidney Calculi
Interventions
MOSES
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Sep 9, 2026, 1:58 AM EDT
Completed Not applicable Interventional

Randomized Trial for Extraction of Difficult Bile Duct Stones

NCT00852072
View directory record Official record
Conditions
Common Bile Duct Stones
Interventions
Single-operator cholangioscopy-guided laser lithotripsy, Balloon Sphincteroplasty
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
18 Years to 100 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Oct 9, 2019 · Synced Sep 9, 2026, 1:58 AM EDT
Completed Not applicable Interventional Results available

Thulium vs. Hol:YAG Laser

NCT05808257
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Thulium Fibre Laser, Holmium:Yttrium-Aluminum-Garnet
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Sep 9, 2026, 1:58 AM EDT
Completed Not applicable Interventional

Laser Versus Mechanical Lithotripsy of Bile Duct Stones

NCT01759979
View directory record Official record
Conditions
Choledocholithiasis
Interventions
Laser and mechanical lithotripsy, Mechanical Lithotripsy
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Sep 9, 2026, 1:58 AM EDT
Recruiting Not applicable Interventional

Differences in Postoperative Symptoms With Four Ureteral Stents

NCT06083051
View directory record Official record
Conditions
Urinary Stone
Interventions
6Fr Percuflex ureteral stents, 6Fr Tria ureteral stents, 4.8Fr Tria ureteral stents, 4.8Fr Percuflex ureteral stents
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 89 Years
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 9, 2026, 1:58 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Papillary Balloon Dilation Versus Intraductal Lithotripsy

NCT03536247
View directory record Official record
Conditions
Choledocholithiasis
Interventions
Initial therapy with papillary balloon dilation, Initial therapy with intraductal lithotripsy
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 115 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 14, 2022 · Synced Sep 9, 2026, 1:58 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Ureteroscopic Laser Modality on Total Lasing Time and Total Energy in Patients With Large, Dense Renal Calculi

NCT05869890
View directory record Official record
Conditions
Renal Calculi
Interventions
MOSES laser system
Device
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2025 · Synced Sep 9, 2026, 1:58 AM EDT