Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 30, 2026, 8:35 AM EDT

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Showing 1–24 of 38 matching trials from the live ClinicalTrials.gov search.
Conditions
Traumatic Brain Injury, Closed Head Injury, Cognitive Dysfunction
Interventions
Real LED Intervention, Sham LED Intervention
Device
Lead sponsor
Boston VA Research Institute, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Abscess
Interventions
Methylene Blue, Lipid Emulsion, Insertion of optical fiber, Laser Illumination (pre-defined dose), Optical Spectroscopy Measurement, Laser Illumination (patient-specific dose), Standard of care abscess drainage
Drug · Device · Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
2
States / cities
Rochester, New York
Conditions
Sports-related Concussion
Interventions
Photobiomodulation therapy (PBMt), Standard of Care
Device · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
13 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Houston, Texas
Conditions
Oropharyngeal Mucositis, Myeloablative Hematopoietic Cell Transplantation, Low Level Light Therapy
Interventions
Low Level Light Therapy
Device
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
4 Years to 25 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts
Conditions
Peripheral Lung Tumor
Interventions
Padeliporfin Vascular Targeted Photodynamic (VTP) therapy
Combination Product
Lead sponsor
Impact Biotech Ltd
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Ischemic Stroke
Interventions
Transcranial Laser Therapy
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
3
States / cities
Englewood, Colorado • Columbia, South Carolina • Spokane, Washington
Completed Not applicable Interventional Results available

Transcranial Laser Therapy for Major Depressive Disorder

NCT01538199
Conditions
Major Depressive Disorder
Interventions
Near-infrared radiation via Transcranial LED Therapy, Sham device
Device
Lead sponsor
Paolo Cassano
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Boston, Massachusetts • Chelsea, Massachusetts
Conditions
Knee Osteoarthritis
Interventions
Physical Therapy, Platelet-Rich Plasma Injection, Photobiomodulation Therapy
Other · Biological · Device
Lead sponsor
Musculoskeletal Injury Rehabilitation Research for Operational Readiness
Federal
Eligibility
18 Years to 64 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tacoma, Washington
Conditions
Obesity, Body Weight, Fat Burn, Cellulite, Abdominal Fat, Adipose Tissue Atrophy
Interventions
Care as Usual Group, Sham Group
Device
Lead sponsor
IR Technology, LLC
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Hixson, Tennessee
Conditions
Traumatic Brain Injury, Post-Concussion Syndrome, Concussion, Brain
Interventions
Float-REST, Photobiomodulation
Other
Lead sponsor
West Virginia University
Other
Eligibility
14 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Morgantown, West Virginia
Conditions
Rectal Cancer, Colorectal Cancer
Interventions
Photoacoustic imaging, photoacoustic microscopy, Endorectal photoacoustic imaging probe, Reader Performance
Device · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
19 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Prostate Cancer
Interventions
Photodynamic Therapy (PDT), Verteporfin Injection
Device · Drug
Lead sponsor
SpectraCure AB
Industry
Eligibility
18 Years and older · Male only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
New York, New York
Conditions
Epilepsy
Interventions
Photobiomodulation
Other
Lead sponsor
Cynthia Kerson
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
North Miami, Florida • Cincinnati, Ohio • Warren, Ohio + 1 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

ELIXIR MDTM Satisfaction Clinical Trial

NCT07676643
Conditions
Postoperative Complications, Plastic Surgery
Interventions
Photobiomodulation
Device
Lead sponsor
Elixir MD Inc
Industry
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Gulf War Veterans Illness, Neurobehavioral Manifestations, Memory Disorders
Interventions
Real LED Treatment, Sham LED Treatment
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
38 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
San Francisco, California • Boston, Massachusetts
Conditions
Prostate Cancer
Interventions
WST 11 -mediated -VTP
Drug
Lead sponsor
Steba Biotech S.A.
Other
Eligibility
18 Years and older · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
5
States / cities
Los Angeles, California • Atlanta, Georgia • St Louis, Missouri + 1 more
Conditions
Pancreatic Cancer Patients Diagnosed With Locally Advanced or Metastatic Pancreatic Cancer Not Amenable to Curative Surgical Resection, Pancreatic Cancer Borderline, Pancreatic Cancer Resectable
Interventions
ASP-1929 photoimmunotherapy
Combination Product
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2033
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Circumference Reduction
Interventions
Lay End Users, Treatment Subject Group
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Colorado Springs, Colorado
Conditions
Cervical Cancer, Cervical Intraepithelial Neoplasia Grade 2, Cervical Intraepithelial Neoplasia Grade 3
Interventions
motexafin lutetium, photodynamic therapy, loop electrosurgical excision procedure, laboratory biomarker analysis
Drug · Procedure · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 65 Years · Female only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Revitalize Cognition: Near Infrared Stimulation in Older Adults

NCT02582593
Conditions
Aging
Interventions
MedX 1116 Rehab Console, Sham MedX 1116 Rehab Console
Device
Lead sponsor
University of Florida
Other
Eligibility
62 Years to 99 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
2
States / cities
Gainesville, Florida
Conditions
Diabetic Retinopathy (DR), Age-related Macular Degeneration (AMD), Mid-peripheral Drusen Formation, Diabetic Macular Edema (DME)
Interventions
Photobiomodulation, Ketogenic diet
Behavioral
Lead sponsor
Bristlecone Health, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Eagan, Minnesota
Conditions
Venous Stasis Ulcer
Interventions
Erchonia ML Scanner (MLS), Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
40 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Revitalize Study in Older Adults at Risk for Alzheimer's Disease

NCT04018092
Conditions
Cognitive Aging, Alzheimer Disease, Protection Against
Interventions
Active NIR-PBM, Sham NIR-PBM
Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 89 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Tucson, Arizona • Gainesville, Florida
Conditions
Abscess
Interventions
Methylene Blue, 20% I.V. Fat Emulsion, Insertion of optical fiber, Laser illumination, 5 minutes, Laser illumination, 10 minutes, Laser illumination, 15 minutes, Laser illumination, 20 minutes, Laser illumination, 25 minutes, Laser illumination, 30 minutes, Optical spectroscopy measurement
Drug · Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
1
States / cities
Rochester, New York