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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:56 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 1,020 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Laser therapy Clear all

Conditions: Varicose Veins
Interventions: Bright Tip Laser Fiber, Bare Tip Laser Fiber; Device
Lead sponsor: Vascular Solutions LLC; Industry
Eligibility: 18 Years and older
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 7
States / cities: Dothan, Alabama • Scottsdale, Arizona • Hollywood, Florida + 4 more

Conditions: Acne
Interventions: Topical Antioxidant Serum, AviClear Laser; Drug · Device
Lead sponsor: Austin Institute for Clinical Research; Network
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Pflugerville, Texas

Conditions: Wrinkles, Striae
Interventions: M22 ResurFX module; Device
Lead sponsor: Lumenis Be Ltd.; Industry
Eligibility: 25 Years to 55 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 2
States / cities: San Diego, California • New York, New York

Conditions: Choroidal Melanoma, Indeterminate Lesions, Uveal Melanoma, Ocular Melanoma
Interventions: Bel-sar, Suprachoroidal Microinjector, Infrared Laser, Sham Infrared Laser, Sham Microinjector; Drug · Device
Lead sponsor: Aura Biosciences; Industry
Eligibility: 18 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 25
States / cities: Los Angeles, California • Palo Alto, California • Sacramento, California + 20 more

Conditions: Dry Eye Syndrome
Interventions: IPL, Sham IPL, MGX; Device · Procedure
Lead sponsor: Lumenis Be Ltd.; Industry
Eligibility: 22 Years to 85 Years
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Nashville, Tennessee • Austin, Texas

Conditions: Skin Texture, Pigmented Lesions
Interventions: Nonablative Fractional Diode Laser; Device
Lead sponsor: Candela Corporation; Industry
Eligibility: 21 Years to 70 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Marlborough, Massachusetts

Conditions: Rhinosinusitis
Interventions: Laser + ICG, Laser only; Device
Lead sponsor: New York Head & Neck Institute; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 3
States / cities: New York, New York

Conditions: Port Wine Stains
Interventions: Rapamycin cream, Pulsed dyed laser; Drug · Procedure
Lead sponsor: AFT Pharmaceuticals, Ltd.; Industry
Eligibility: Up to 10 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Corpus Christi, Texas

Conditions: Rosacea, Papulopustular, Rosacea, Erythematotelangiectatic
Interventions: KTP Laser Therapy, Radiofrequency microneedling; Device
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Miami Beach, Florida

Conditions: Macular Degeneration
Interventions: Low-Intensity Laser Treatment; Procedure
Lead sponsor: National Eye Institute (NEI); NIH
Eligibility: 50 Years and older
Enrollment: 1,052 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2006
U.S. locations: 24
States / cities: Mesa, Arizona • Peoria, Arizona • San Francisco, California + 20 more

Conditions: Myopia, Astigmatism
Interventions: Visumax spherocylindrical treatment; Device
Lead sponsor: United States Naval Medical Center, San Diego; Federal
Eligibility: 22 Years and older
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: San Diego, California

Conditions: Vascular Lesion
Interventions: Tandem 532/1064 nm Laser; Device
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Irvine, California

Conditions: Glaucoma
Interventions: Baerveldt Glaucoma Implant 350-mm2 / BG101-350, Transscleral Diode Laser Cyclophotocoagulation, Ahmed Model FP7 Flexible Plate, Baerveldt Glaucoma Implant 250-mm2 / BG103-250; Device · Procedure
Lead sponsor: Robert Feldman; Other
Eligibility: 18 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 23
States / cities: La Jolla, California • Los Angeles, California • Miami, Florida + 18 more

Conditions: Sports-related Concussion
Interventions: Photobiomodulation therapy (PBMt), Standard of Care; Device · Other
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 13 Years to 18 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Corneal Epithelium Defect
Interventions: 0.3% hypromellose; Drug
Lead sponsor: Augusta University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Diabetic Foot Ulcer
Interventions: Not listed
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Macular Edema, Branch Retinal Vein Occlusion
Interventions: Ranibizumab, Peripheral Laser; Drug · Procedure
Lead sponsor: Retina Associates of Florida, P.A.; Other
Eligibility: 18 Years to 90 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Brain Metastases
Interventions: MRI; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Diabetic Retinopathy, Diabetic Macular Edema
Interventions: Ranibizumab (Lucentis), Argon Laser; Drug · Procedure
Lead sponsor: Rocky Mountain Retina Consultants; Other
Eligibility: 18 Years and older
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Chronic Pain
Interventions: Acupuncture, myofascial therapy, microcurrent therapy, LASER, extracorporeal shockwave therapy, Pulsed electromagnetic therapies, Miscellaneous integrative medicine; Other
Lead sponsor: David Moss; Federal
Eligibility: 18 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Nellis Air Force Base, Nevada

Conditions: Abdominoplasty
Interventions: Ablation and skin resurfacing, eMatrixCO2; Procedure · Device
Lead sponsor: Syneron Medical; Industry
Eligibility: 20 Years to 60 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2009
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Obsessive-Compulsive Disorder
Interventions: Laser Interstitial Thermal Therapy; Device
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 90 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2032
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Erythematotelangiectatic Rosacea, Papulopustular Rosacea
Interventions: 532nm KTP Laser vs 595nm Pulse Dye Laser; Device
Lead sponsor: Cutera Inc.; Industry
Eligibility: 20 Years to 80 Years · Female only
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Lung Cancer
Interventions: PHOTODYNAMIC THERAPY (PDT); Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 50 Years to 75 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1994 – 2006
U.S. locations: 1
States / cities: Rochester, Minnesota

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The BRILLIANT Study

Single-Blind Study Assessing the Use of a Topical Antioxidant With A Series of Laser Procedures to Reduce Sebum Production

Clinical Evaluation of M22 ResurFX 1565nm Module

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

Effectiveness of Intense Pulsed Light for Improving Dry Eye Syndrome

Nonablative Fractional Diode Laser for Treatment of Skin Resurfacing and Pigmented Lesions

Laser Assisted Treatment of Chronic Sinusitis With and Without Light Activated Agents

Rapamycin Dose-Ranging Efficacy Study in Port Wine Stains

Rosacea Radiofrequency Microneedling

Complications of Age-Related Macular Degeneration Prevention Trial

SMILE (Small Incision Lenticule Extraction) in the DoD (Department of Defense)

Treatment of Vascular Lesions With a Tandem 532/1064 nm Laser

The American Glaucoma Society (AGS) Second Aqueous Shunt Implant vs. Transscleral Cyclophotocoagulation Treatment Study (ASSISTS)

Assessing the Effects of Photobiomodulation on Clinical Recovery From Concussion in Adolescents

GenTeal in Perioperative Treatment of Laser Assisted in Situ Keratomileusis LASIK Patients

Treatment of Foot and Leg Ulcers Using a Laser

REtinal Vein OccLUsion Treatment With Scatter Laser Guided by UWFA in combiNAtion With Ranibizumab Study

MRI Following Stereotactic Radiosurgery (SRS) for Brain Metastases

Efficacy Study of Lucentis in the Treatment of Diabetic Macular Edema

Prospective Assessment of Integrative Therapies for Neuromusculoskeletal Pain (PAIN)

In-vivo Analysis of a Fractional CO2 Laser System (eMatrixCO2) Intended for Treatment of Soft Tissue

Ventral Capsulotomy for Intractable OCD

Excel V 532 nm KTP Laser for Treatment of Erythematotelangiectatic Rosacea & Papulopustular Rosacea

Photodynamic Therapy (PDT) in Lung Cancer