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ClinicalTrials.gov public records Last synced Oct 15, 2026, 1:28 AM EDT

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Showing 361–384 of 1,059 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Laser treatment Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

VELOS for the Treatment of Vascular Lesions and Skin Rejuvenation

NCT02468453
View directory record Official record
Conditions
Vascular Lesions, Photoaging
Interventions
velos
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
4
States / cities
San Diego, California • Wayland, Massachusetts • Edina, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 6, 2018 · Synced Oct 15, 2026, 1:28 AM EDT
Completed Phase 4 Interventional Results available

Clinical and Microbiologic Outcomes of aPDT in the Non-surgical Treatment of Implant Inflammation

NCT04187053
View directory record Official record
Conditions
DENT IMPLANTS, LASER
Interventions
Conventional mechanical therapy, Saline, Methylene Blue, Light emitting laser, Non-light emitting laser
Procedure · Drug · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Oct 15, 2026, 1:28 AM EDT
Not listed Phase 4 Interventional

TRAP Intervention STudy: Early Versus Late Intervention for Twin Reversed Arterial Perfusion Sequence

NCT02621645
View directory record Official record
Conditions
Twin Reversal Arterial Perfusion Syndrome
Interventions
Early selective reduction of TRAP mass, Late selective reduction of TRAP mass, Ultrasound-guided intrafetal ablation using a 18 to 20 Gauge needle, Ultrasound-guided intrafetal ablation using a 17 to 20 Gauge needle, Laser coagulation of the cord or anastomising vessels through a 17 Gauge to 7 French trocar, with a 1-1,3 mm fetoscope and a 400 µm laser fiber
Procedure · Device
Lead sponsor
Universitaire Ziekenhuizen KU Leuven
Other
Eligibility
18 Years and older · Female only
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2024 · Synced Oct 15, 2026, 1:28 AM EDT
Completed Not applicable Interventional Results available

Assessment Of Infrared Photobiotherapy for Improved Wound Healing

NCT00426166
View directory record Official record
Conditions
Wound Healing
Interventions
Low Level Laser Therapy
Device
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
18 Years to 85 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Oct 15, 2026, 1:28 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

A Comparison of Photorefractive Keratectomy (PRK), PRK With Mitomycin-C and Laser Subepithelial Keratomileusis (LASEK) in the Treatment of Moderate and High Myopia

NCT00415077
View directory record Official record
Conditions
MODERATE AND HIGH MYOPIA
Interventions
PRK, MMC PRK, LASEK
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
960 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2004
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 16, 2010 · Synced Oct 15, 2026, 1:28 AM EDT
Not listed Not applicable Interventional

Near-Infrared Laser Stimulation for Various Neurological Conditions

NCT04489082
View directory record Official record
Conditions
Refractory Depression, Anxiety Disorders, Neurodegenerative Diseases, Traumatic Brain Injury, Chronic Traumatic Encephalopathy
Interventions
Near Infrared Laser Stimulation
Device
Lead sponsor
Neurological Associates of West Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Oct 15, 2026, 1:28 AM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Effect of Low Level Laser Light on Low Back Pain

NCT02538523
View directory record Official record
Conditions
Low Back Pain
Interventions
Erchonia FX-635, Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Chandler, Arizona • San Mateo, California • Bloomfield, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Oct 15, 2026, 1:28 AM EDT
Completed Not applicable Interventional

Laser Treatment of Basal Cell Carcinoma Under Imaging Guidance

NCT05138328
View directory record Official record
Conditions
Carcinoma, Basal Cell
Interventions
Treatment of basal cell carcinoma with Nd:YAG laser under imaging guidance of optical coherence tomography (OCT)
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 105 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 15, 2025 · Synced Oct 15, 2026, 1:28 AM EDT
Completed Phase 4 Interventional Results available

Long-Term Efficacy & Safety of Aflibercept IVT for the Treatment of DME in Subjects Who Completed the VISTA-DME Trial

NCT02299336
View directory record Official record
Conditions
Diabetic Macular Edema
Interventions
Aflibercept, Focal Laser
Drug · Procedure
Lead sponsor
Greater Houston Retina Research
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Houston, Texas • Katy, Texas • The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2019 · Synced Oct 15, 2026, 1:28 AM EDT
Completed Phase 4 Interventional Results available

Widefield Angiography Guided Targeted-retinal Photocoagulation Combined With Anti VEgf Intravitreal Injections for the Treatment of Ischemic Central Retinal Vein Occlusion, Hemi Retinal Vein Occlusion, and Branch Retinal Vein Occlusion

NCT01710839
View directory record Official record
Conditions
Central Retinal, Hemi Retinal & Brach Retinal Vein Occlusions
Interventions
0.5mg Ranibizumab, Targeted Pan Retinal Photocoagulation
Drug · Procedure
Lead sponsor
Charles C Wykoff, PhD, MD
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
3
States / cities
Houston, Texas • Katy, Texas • The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Sep 8, 2017 · Synced Oct 15, 2026, 1:28 AM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers

To Determine the Efficacy of a Laser Device for the Treatment of Hidradenitis Suppurativa

NCT00367328
View directory record Official record
Conditions
Hidradenitis Suppurativa
Interventions
1320nm Nd: YAG nonablative laser
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 15, 2026, 1:28 AM EDT
Recruiting Not applicable Interventional

GyroStim for Post Concussion Syndrome

NCT07527663
View directory record Official record
Conditions
Post Concussion Syndrome
Interventions
Sensorimotor Multi-axis Automated Rotational Therapy (SMART) utilizing GyroStim device, Physical therapy and speech therapy/cognitive rehabilitation therapy
Device · Other
Lead sponsor
Neuroscience Group
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Appleton, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 15, 2026, 1:28 AM EDT
Completed No phase listed Observational Results available

Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease

NCT04229563
View directory record Official record
Conditions
Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
Interventions
AURYON Atherectomy System
Device
Lead sponsor
Angiodynamics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
10
States / cities
Scottsdale, Arizona • Tucson, Arizona • Davenport, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 15, 2026, 1:28 AM EDT
Completed Phase 4 Interventional Results available

Treatment of Keloids With Fractional Erbium Laser-Assisted 5-Fluorouracil Versus Laser-Assisted Corticosteroid

NCT04786210
View directory record Official record
Conditions
Keloid Scar
Interventions
Fractional erbium:YAG-assisted drug delivery of 5-fluorouracil, Fractional erbium:YAG-assisted drug delivery of triamcinolone acetonide
Combination Product
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 89 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 26, 2024 · Synced Oct 15, 2026, 1:28 AM EDT
Active, not recruiting Phase 2 Interventional

177LuPSMA in Renal Cell Carcinoma

NCT06964958
View directory record Official record
Conditions
Renal Cell Carcinoma, Advanced Clear Cell Renal Cell Carcinoma, Kidney Cancer
Interventions
177Lu-PSMA-617
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 15, 2026, 1:28 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Metabolism Enhancement by Laser Therapy

NCT06899958
View directory record Official record
Conditions
Metabolism Disorder
Interventions
Fractional Laser
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 15, 2026, 1:28 AM EDT
Completed Not applicable Interventional Results available

Photobiomodulation Therapy Using the Realief Therapy System for the Treatment of Chemotherapy-associated Peripheral Neuropathy

NCT02000908
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
photobiomodulation, Sham treatment, Physiotherapy
Device · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Oct 15, 2026, 1:28 AM EDT
Completed Not applicable Interventional Results available

Pediatric Laser Acupuncture and Renal Biopsy

NCT01879826
View directory record Official record
Conditions
Pain, Anxiety
Interventions
Aculaser applied to kidney points, Aculaser applied to sham points
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
7 Years to 25 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Oct 15, 2026, 1:28 AM EDT
Completed Not applicable Interventional Results available

Transcranial Laser Therapy, Continuous and Pulsed Light, for Major Depressive Disorder (ELATED-3)

NCT02959307
View directory record Official record
Conditions
Depression, Major Depressive Disorder
Interventions
Transcranial Light Therapy, Sham Transcranial Light Therapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Oct 15, 2026, 1:28 AM EDT
Completed Phase 1 Interventional

Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas

NCT06132165
View directory record Official record
Conditions
Neurofibromatosis 1
Interventions
Deoxycholic Acid, Polidocanol, 1064nm Nd:YAG laser, 755nm Alexandrite Laser
Drug · Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 15, 2026, 1:28 AM EDT
Completed Not applicable Interventional

Laryngopharyngeal Reflux Before and After Cricopharyngeal Myotomy

NCT01880892
View directory record Official record
Conditions
Laryngopharyngeal Reflux, Zenker's Diverticulum
Interventions
Cricopharyngeal myotomy, PH probe Testing
Procedure · Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Oct 15, 2026, 1:28 AM EDT
Not listed Not applicable Interventional

Study of the Use of Laser Light to Treat Osteoarthritis of the Hand.

NCT00254111
View directory record Official record
Conditions
Osteoarthritis
Interventions
Ultra Probe Laser System
Device
Lead sponsor
TriTech Manufacturing
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
3
States / cities
Phoenix, Arizona • Long Beach, California • Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 15, 2005 · Synced Oct 15, 2026, 1:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MonaLisa Touch Randomized Double-Blind Placebo Controlled Study

NCT03331328
View directory record Official record
Conditions
Genitourinary Syndrome of Menopause
Interventions
MonaLisa Touch
Device
Lead sponsor
Michigan Institution of Women's Health PC
Other
Eligibility
Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dearborn, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 15, 2026, 1:28 AM EDT
Terminated Not applicable Interventional Results available

Efficacy of the Erchonia Corporation THL™ for Providing Relief of Tinnitus Symptoms

NCT05374421
View directory record Official record
Conditions
Tinnitus
Interventions
Erchonia® THL™, Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Concord, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 15, 2026, 1:28 AM EDT