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ClinicalTrials.gov public records Last synced Oct 15, 2026, 2:49 AM EDT

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Showing 409–432 of 1,059 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Laser treatment Clear all
Completed Phase 2 Interventional Results available

Decitabine in Treating Patients With Previously Untreated Acute Myeloid Leukemia

NCT00492401
View directory record Official record
Conditions
Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Secondary Acute Myeloid Leukemia, Untreated Adult Acute Myeloid Leukemia
Interventions
decitabine, laboratory biomarker analysis, pharmacological study, high performance liquid chromatography, microarray analysis, RNA analysis, mass spectrometry, DNA methylation analysis, matrix-assisted laser desorption/ionization time of flight mass spectrometry
Drug · Other · Genetic
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 27, 2016 · Synced Oct 15, 2026, 2:49 AM EDT
Completed No phase listed Observational

CardioGenesis Transmyocardial Revascularization 1-Year Follow-Up Study

NCT02694861
View directory record Official record
Conditions
Class IV Angina
Interventions
Not listed
Lead sponsor
CryoLife, Inc.
Industry
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
Jacksonville, Florida • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced Oct 15, 2026, 2:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation

NCT06366503
View directory record Official record
Conditions
Photoaging, Wrinkle, Skin Laxity
Interventions
Fractional Ablative CO2 Laser, Facial Cleanser, Facial Moisturizer, Sunscreen, Basic Ointment
Procedure · Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 65 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Blue Ash, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 15, 2026, 2:49 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Combined 755nm Alexandrite Laser With Bipolar RF for Hair Reduction

NCT02465788
View directory record Official record
Conditions
Excess Hair Growth
Interventions
GentleTouch
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 24, 2016 · Synced Oct 15, 2026, 2:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study to Compare Two Treatments for Axillary Hidradenitis Suppurativa: Carbon Dioxide Laser Versus Surgical Deroofing

NCT02163746
View directory record Official record
Conditions
Hidradenitis Suppurativa
Interventions
CO2 (carbon dioxide) laser, Surgical Deroofing
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
13 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Oct 15, 2026, 2:49 AM EDT
Terminated Not applicable Interventional Results available

Low-level Laser Therapy in Patients With Chronic Fibromyalgia

NCT02948634
View directory record Official record
Conditions
Chronic Pain
Interventions
Sham Phoenix Laser Treatment, Active Phoenix Laser Treatment
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Oct 15, 2026, 2:49 AM EDT
Recruiting Not applicable Interventional

Pilot Trial Assessing the Effectiveness of Laser Hair Depilation on Pilonidal Disease Recurrence in Patients With Darker Skin Color

NCT06406621
View directory record Official record
Conditions
Pilonidal Disease
Interventions
Laser hair depilation, Standard of Care (SOC)
Procedure · Other
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
10 Years to 21 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 15, 2026, 2:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Cutera Enlighten™ Laser With Micro-Lens Array (MLA) Handpiece Attachment

NCT03430921
View directory record Official record
Conditions
Scarring, Acne
Interventions
Enlighten™ Laser and a MLA Attachment
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Brisbane, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2023 · Synced Oct 15, 2026, 2:49 AM EDT
Completed Phase 3 Interventional

Steroid Injections vs. Standard Treatment for Macular Edema Due to Retinal Blood Vessel Blockage

NCT00106132
View directory record Official record
Conditions
Retinal Vein Occlusion, Macular Edema, Cystoid, Macular Edema
Interventions
Triamcinolone Acetonide
Drug
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
Not listed
Enrollment
1,260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 15, 2026, 2:49 AM EDT
Completed Not applicable Interventional

Clinical Study Evaluating the Safety and Effectiveness of the NIRA Laser M2.1 for the Treatment of Full-Face Wrinkles

NCT07572331
View directory record Official record
Conditions
Skin Ageing, Facial Wrinkles, Acne, Skin Elasticity, Infraorbital Dark Circle Severity, Skin Firmness, UV Spots, Skin Texture, Skin Pores, Brown Spots, Porphyrins, Red Spots
Interventions
NIRA Laser M2.1, Topical
Device · Other
Lead sponsor
NIRA Innovations Inc.
Industry
Eligibility
35 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Beverly, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 15, 2026, 2:49 AM EDT
Completed Not applicable Interventional

MonaLisa Touch Laser for the Treatment of Vulvar Lichen Sclerosus

NCT03665584
View directory record Official record
Conditions
Lichen Sclerosus
Interventions
FxCO2 Laser, Sham Laser
Device
Lead sponsor
Center for Vulvovaginal Disorders
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Oct 15, 2026, 2:49 AM EDT
Terminated Not applicable Interventional Results available

The BRILLIANT Study

NCT00618514
View directory record Official record
Conditions
Varicose Veins
Interventions
Bright Tip Laser Fiber, Bare Tip Laser Fiber
Device
Lead sponsor
Vascular Solutions LLC
Industry
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
7
States / cities
Dothan, Alabama • Scottsdale, Arizona • Hollywood, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2015 · Synced Oct 15, 2026, 2:49 AM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of a New Treatment in Combination With Laser for Diabetic Macular Edema

NCT00464685
View directory record Official record
Conditions
Diabetic Macular Edema
Interventions
Dexamethasone, Sham injection, Laser Photocoagulation
Drug · Procedure
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Artesia, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2019 · Synced Oct 15, 2026, 2:49 AM EDT
Completed Not applicable Interventional Results available

Efficacy of 1540 Nanometer Erbium Glass Laser to Improve Benign Dermatofibromas

NCT03392935
View directory record Official record
Conditions
Dermatofibroma of Skin
Interventions
1540 nanometer Erbium glass laser
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Oct 15, 2026, 2:49 AM EDT
Completed No phase listed Observational Results available

Laser Therapy for Treatment of Urogenital Symptoms in Women

NCT03681678
View directory record Official record
Conditions
Genitourinary System; Disorder, Female, Burning Vagina, Dyspareunia, Irritation; Vagina, Menopause Related Conditions, Urinary Incontinence, Urinary Bladder, Overactive, Urinary Tract Infections, Stress Urinary Incontinence
Interventions
fCO2 Laser Therapy Group
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 15, 2026, 2:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of a Novel Microlens Array Device for Skin Rejuvenation

NCT02888626
View directory record Official record
Conditions
Wrinkles, Scars
Interventions
Microlens Array
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
20 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Brisbane, California
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Oct 15, 2026, 2:49 AM EDT
Completed Not applicable Interventional

Clinical and Histological Evaluation of the 755nm Alexandrite Laser With Handpiece for the Treatment of Scars

NCT01813786
View directory record Official record
Conditions
Scars
Interventions
755nm Alexandrite Laser with handpiece 2, 755nm Alexandrite Laser with handpiece 1, 755nm Alexandrite Laser with handpiece 3
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 28, 2020 · Synced Oct 15, 2026, 2:49 AM EDT
Recruiting Not applicable Interventional

Light Therapy Device for Neonatal Intraventricular Hemorrhage Grade 3 and 4

NCT06797219
View directory record Official record
Conditions
Intraventricular Hemorrhage of Prematurity, Hydrocephalus
Interventions
Low Level Laser Therapy for Intraventricular Hemorrhage of Prematurity
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
0 Days to 1 Month
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Oct 15, 2026, 2:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Evaluation of LightSheer Duet 805nm HS Handpiece

NCT01801202
View directory record Official record
Conditions
Hair Removal
Interventions
LightSheer Duet HS handpiece
Device
Lead sponsor
Lumenis Be Ltd.
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2015 · Synced Oct 15, 2026, 2:49 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Study of the Efficacy of 532nm Laser and 1064 nm Laser in the Treatment of Cutaneous Lupus Erythematous Versus Topical Corticosteroids Alone

NCT03639857
View directory record Official record
Conditions
Cutaneous Lupus
Interventions
532nm laser, 1064nm laser, Topical corticosteroid
Device · Drug
Lead sponsor
David Weinstein
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 21, 2021 · Synced Oct 15, 2026, 2:49 AM EDT
Terminated Not applicable Interventional Results available

Photobiomodulation for the Management of Temporomandibular Disorder Pain

NCT04415281
View directory record Official record
Conditions
Pain Related to TMD
Interventions
THOR® laser system, sham THOR® laser system
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Oct 15, 2026, 2:49 AM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Investigation of Laser Assisted Drug Delivery of NanoDOX®

NCT05411484
View directory record Official record
Conditions
Wounds and Injury
Interventions
NanoDOX® Hydrogel, CO2 Ablative Fractional Laser
Drug · Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 15, 2026, 2:49 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Clinical Study to Evaluate the Performance of the PicoWayTM 1064 nm/ 785 nm/ 532nm Picosecond Laser for Tattoo Removal

NCT02700932
View directory record Official record
Conditions
Tattoo; Pigmentation
Interventions
PicoWay
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 15, 2026, 2:49 AM EDT
Active, not recruiting Not applicable Interventional

LITT Followed by Hypofractionated RT for Recurrent Gliomas

NCT04181684
View directory record Official record
Conditions
Glioblastoma, Brain Tumor, Glioma, Neoplasms
Interventions
Procedure: LITT, Hypo-Fractionated Radiation Therapy
Device · Radiation
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
22 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
4
States / cities
Baltimore, Maryland • Bel Air, Maryland • Columbia, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 15, 2026, 2:49 AM EDT