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ClinicalTrials.gov public records Last synced Oct 25, 2026, 6:14 AM EDT

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Showing 97–120 of 146 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Left ventricular function Clear all
Completed Phase 4 Interventional Results available

Effect of Exenatide on Liver and Heart Fat and Inflammation

NCT01951651
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Exenatide, Glipizide
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
30 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2016 · Synced Oct 25, 2026, 6:14 AM EDT
Withdrawn Not applicable Interventional

Study of Percutaneous Renal Artery Intervention for Patient With Heart Failure

NCT01403714
View directory record Official record
Conditions
Heart Failure
Interventions
Renal Artery Stenting
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 2, 2012 · Synced Oct 25, 2026, 6:14 AM EDT
Recruiting Not applicable Interventional

Feasibility of the SCD in Cardiorenal Syndrome Patients Awaiting LVAD

NCT03836482
View directory record Official record
Conditions
Acute on Chronic Systolic Congestive Heart Failure, Cardiorenal Syndrome
Interventions
Selective Cytopheretic Device
Device
Lead sponsor
SeaStar Medical
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 25, 2026, 6:14 AM EDT
Completed Not applicable Interventional Results available

Effects of Nebivolol on Exercise Tolerance and Left Ventricular Systolic and Diastolic Function

NCT01056718
View directory record Official record
Conditions
Hypertension
Interventions
Nebivolol
Drug
Lead sponsor
Mercy Research
Other
Eligibility
18 Years to 90 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 25, 2026, 6:14 AM EDT
Withdrawn Not applicable Interventional

Impact of Cardiac Resynchronization Therapy on Right Ventricular Function in Left Ventricular Assist Device Patients

NCT02169076
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 5, 2017 · Synced Oct 25, 2026, 6:14 AM EDT
Recruiting Phase 2 Interventional

Physiology of Unloading VA ECMO Trial

NCT06336655
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
IABP
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 25, 2026, 6:14 AM EDT
Terminated Phase 2 Interventional Results available

The Use of Ranolazine for Atrial Fibrillation and Diastolic Heart Failure

NCT01887353
View directory record Official record
Conditions
Atrial Fibrillation, Heart Failure
Interventions
Ranolazine, Placebo
Drug
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Jul 20, 2015 · Synced Oct 25, 2026, 6:14 AM EDT
Terminated Not applicable Interventional

Aldosterone Blockade to Prevent Myocardial Remodeling In Patients With Controlled Essential Hypertension

NCT00980031
View directory record Official record
Conditions
Myocardial Remodeling
Interventions
Eplerenone, Lactose Tablet
Drug
Lead sponsor
Creighton University
Other
Eligibility
19 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Mar 28, 2014 · Synced Oct 25, 2026, 6:14 AM EDT
Recruiting No phase listed Observational

Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease

NCT01099982
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
13 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2030
U.S. locations
3
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 25, 2026, 6:14 AM EDT
Completed Phase 1 Interventional Results available

The Impact of Zinc Supplementation on Left Ventricular Function in Nonischemic Cardiomyopathy

NCT00696410
View directory record Official record
Conditions
Heart Failure, Cardiomyopathies
Interventions
Zinc Acetate
Drug
Lead sponsor
University of Michigan
Other
Eligibility
21 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Oct 25, 2026, 6:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Vitamin D Supplementation on Cardiac Structure and Function

NCT01630213
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Vitamin D3 + fish oil/fish oil placebo, Vitamin D3 placebo + fish oil/fish oil placebo
Dietary Supplement
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years and older
Enrollment
1,025 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 6, 2022 · Synced Oct 25, 2026, 6:14 AM EDT
Completed No phase listed Observational

Biomarkers and Cardiac MRI as Early Indicators of Cardiac Exposure Following Breast Radiotherapy

NCT02496260
View directory record Official record
Conditions
Breast Cancer
Interventions
Research Cardiac MRI, Biomarkers
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Oct 25, 2026, 6:14 AM EDT
Completed Phase 4 Interventional Results available

Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.

NCT02970669
View directory record Official record
Conditions
Heart Failure, Reduced Ejection Fraction
Interventions
sacubitril/valsartan (LCZ696), enalapril, matching placebo sacubitril/valsartan (LCZ696), matching placebo enalapril
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 80 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
23
States / cities
Fort Payne, Alabama • Beverly Hills, California • Stockton, California + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Oct 25, 2026, 6:14 AM EDT
Withdrawn No phase listed Observational

Diastolic Dysfunction PPCM in Patients With Documented Left Ventricular Systolic Function Recovery

NCT04143997
View directory record Official record
Conditions
Peripartum Cardiomyopathy, Diastolic Dysfunction
Interventions
A clinical Transthoracic echocardiogram
Diagnostic Test
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 23, 2024 · Synced Oct 25, 2026, 6:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating a New Echocardiography Imaging Procedure for Evaluating Heart Function

NCT00661323
View directory record Official record
Conditions
Ischemia, Myocardial Infarction, Ischemic Heart Disease
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Oct 25, 2026, 6:14 AM EDT
Recruiting No phase listed Observational

ASSURE WCD Clinical Evaluation - Post Approval Study (ACE-PAS)

NCT05135403
View directory record Official record
Conditions
Sudden Cardiac Arrest
Interventions
Defibrillation
Device
Lead sponsor
Kestra Medical Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5,179 participants
Timeline
2021 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Oct 25, 2026, 6:14 AM EDT
Terminated No phase listed Observational

Study of Echocardiogram Accuracy in Patients With Mitral Valve Calcification

NCT01442467
View directory record Official record
Conditions
Mitral Annulus Calcification
Interventions
Not listed
Lead sponsor
Creighton University
Other
Eligibility
19 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 1, 2013 · Synced Oct 25, 2026, 6:14 AM EDT
Terminated Not applicable Interventional

Use of 3-D Blood Pool Scintigraphy to Guide Left Ventricular Pacing Lead Placement in Patients Requiring Cardiac Resynchronization Therapy

NCT02669290
View directory record Official record
Conditions
Heart Failure, Left Ventricular Dysfunction, Cardiac Resynchronization Therapy
Interventions
Guided, Non-guided
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Oct 25, 2026, 6:14 AM EDT
Enrolling by invitation No phase listed Observational

Precision Medicine in the CICU: Identifying Proteomic Biomarkers

NCT06642662
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Somascan 5.0
Diagnostic Test
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Days to 5 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 25, 2026, 6:14 AM EDT
Completed No phase listed Observational

Assessment of Exam Findings in Coronavirus Disease 2019 (COVID-19) With Point-of-Care Ultrasonography (POCUS)

NCT04339998
View directory record Official record
Conditions
Coronavirus Infection, COVID, Covid-19, SARS-CoV-2
Interventions
Point-of-Care Ultrasonography (POCUS)
Diagnostic Test
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
2
States / cities
Minneapolis, Minnesota • Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 4, 2023 · Synced Oct 25, 2026, 6:14 AM EDT
Completed Phase 4 Interventional Results available

Effects of Viagra on Heart Function in Patients With Heart Failure

NCT00781508
View directory record Official record
Conditions
Heart Failure, Left Ventricular Dysfunction
Interventions
sildenafil, Placebo
Drug · Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
25 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 2, 2014 · Synced Oct 25, 2026, 6:14 AM EDT
Recruiting Phase 3 Interventional

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

NCT06935370
View directory record Official record
Conditions
Heart Failure
Interventions
vicadrostat, empagliflozin, Placebo
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
4,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
89
States / cities
Beverly Hills, California • Covina, California • Encinitas, California + 75 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 25, 2026, 6:14 AM EDT
Terminated Phase 2 Interventional Results available

Multiple Treatment Session Study to Assess GSK2398852 Administered Following and Along With GSK2315698

NCT03044353
View directory record Official record
Conditions
Amyloidosis
Interventions
GSK2315698 (CPHPC), GSK2398852 (anti-SAP mAb)
Drug · Biological
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 16, 2019 · Synced Oct 25, 2026, 6:14 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Interleukin-1 Receptor Antagonist for the Treatment of Heart Failure in Patients With Left Ventricular Assist Devices

NCT02547766
View directory record Official record
Conditions
Heart Failure
Interventions
Anakinra
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 17, 2020 · Synced Oct 25, 2026, 6:14 AM EDT