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Showing 1–24 of 111 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Leg Extension Exercise Clear all
Terminated Not applicable Interventional

3-month Aerobic and Resistance Exercise Intervention for Individuals Diagnosed With Melanoma

NCT03825913
View directory record Official record
Conditions
Melanoma
Interventions
Exercise Intervention, Wellness Intervention
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 27, 2020 · Synced Sep 2, 2026, 9:19 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women

NCT03888040
View directory record Official record
Conditions
Aging
Interventions
Exercise
Other
Lead sponsor
Marquette University
Other
Eligibility
18 Years to 100 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Sep 2, 2026, 9:19 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Training Induced Muscle-Adipose EV Communication

NCT07106450
View directory record Official record
Conditions
Prediabetes
Interventions
Acute Resistance Exercise
Behavioral
Lead sponsor
Yuan Wen
Other
Eligibility
30 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 2, 2026, 9:19 PM EDT
Terminated Phase 3 Interventional Results available

Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS

NCT01482286
View directory record Official record
Conditions
Polycystic Ovary Syndrome
Interventions
Metformin, Dietary Restriction, Exercise Training
Drug · Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 14, 2022 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Food First Approach to Stimulate Muscle Protein Synthesis in Healthy Adults

NCT03870165
View directory record Official record
Conditions
Hypertrophy
Interventions
Resistance exercise, Salmon, Isolated amino acids and fatty acids
Behavioral · Other · Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 27, 2020 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Type 2 Diabetes and Exercise Function in Single Leg Exercises

NCT01793909
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Single Leg Exercise Training
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 70 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional

Strengthening Exercise and Quadriceps Force During Walking

NCT01538407
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Strength Training
Other
Lead sponsor
Frederiksberg University Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 21, 2014 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional Results available

Exercise Training for the Treatment of Generalized Anxiety Disorder

NCT00953654
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Strength Training, Endurance Training
Other
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 39 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 8, 2016 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional Results available

Time Course Adaptations Using Deuterated Creatine (D3Cr) Method

NCT03573583
View directory record Official record
Conditions
Sarcopenia
Interventions
Resistance Training, Successful Aging
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
70 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutritional Strategies to Augment the Postprandial Muscle Protein Synthetic Response to the Ingestion of a Low Dose of Protein in Middle-aged Women

NCT02918981
View directory record Official record
Conditions
Aging
Interventions
Resistance Exercise, 14 g Whey protein, 6.6 g Whey protein + 1.25 g leucine, 4 g Whey protein + 1.25 g leucine + 2.6 g Whey peptides, 6.6 g Whey protein + 1.25 g leucine + 0.8 g Citrulline, Water control
Behavioral · Dietary Supplement · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 79 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Body's Response to Aerobic Versus Resistance Exercise

NCT00761163
View directory record Official record
Conditions
Exercise
Interventions
Resistance Exercise, Aerobic Exercise, Control (Non-exercise)
Other
Lead sponsor
Purdue University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 16, 2013 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional Results available

The Effect of Exercise on Individuals With Parkinson's Disease

NCT00591344
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Progressive resistance training, Modified Fitness Counts
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years to 67 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 4, 2015 · Synced Sep 2, 2026, 9:19 PM EDT
Not listed Not applicable Interventional

Negative Work Exercise for the Treatment of Knee Arthritis

NCT02098096
View directory record Official record
Conditions
Osteoarthritis, Arthritis
Interventions
Negative Work, Stretching
Other
Lead sponsor
Washington D.C. Veterans Affairs Medical Center
Federal
Eligibility
50 Years to 70 Years · Male only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Sep 2, 2026, 9:19 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Study of Pulmonary Hypertension Peripheral Limitations

NCT05968859
View directory record Official record
Conditions
Pulmonary Arterial Hypertension, Healthy
Interventions
Aerobic Training, Leg Training
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional

A Clinical Trial of Cognitive Multisensory Rehabilitation for Sensory and Motor Recovery in Adults With Spinal Cord Injury

NCT05167032
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Cognitive Multisensory Rehabilitation (CMR), Adaptive fitness
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Molecular Mechanisms of Exercise Benefits to Insulin Resistant People

NCT04158375
View directory record Official record
Conditions
Insulin Resistance, Obesity
Interventions
Resistance Exercise
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years to 75 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

How do the Neck Muscles Influence Head Acceleration During Sport-associated Impact Events in High School Athletes?

NCT03883165
View directory record Official record
Conditions
Sport-related Concussion, Brain Concussion, Healthy
Interventions
high-intensity neck strengthening, Control group
Other
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 19 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 23, 2025 · Synced Sep 2, 2026, 9:19 PM EDT
Recruiting Phase 2Phase 3 Interventional

Epidural Stimulation and Resistance Training After SCI

NCT04782947
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Exoskeletal assisted walking, Epidural Stimulation, Resistance Training, delayed-ES, no-Resistance training
Device · Procedure
Lead sponsor
United States Department of Defense
Federal
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 1, 2026 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome

NCT00445224
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Hip Progressive Resistive Exercise, Quad Progressive Resistive Exercises
Other
Lead sponsor
Timothy Uhl
Other
Eligibility
15 Years to 35 Years · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional

Resistance Exercise Training in Chronic Kidney Disease

NCT03120416
View directory record Official record
Conditions
Chronic Kidney Disease
Interventions
Resistance exercise training
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
21 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Exercise and Muscle Protein Synthesis in Obese Adults

NCT03411681
View directory record Official record
Conditions
Obesity
Interventions
Resistance Exercise
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 45 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Sep 2, 2026, 9:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Diet Synergy in Muscle Protein Synthesis

NCT07367854
View directory record Official record
Conditions
Muscle Protein Synthetic Response to Protein, Muscle Protein Synthesis, Muscle Health, Protein Metabolism, Recreational Activities, Isotope Labeling
Interventions
Resistance Exercise, Potato and Beef, Bread and Beef, Beef
Behavioral · Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
19 Years to 40 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Phase 1Phase 2 Interventional

Physical, Functional and Neural Effects of Two Lower Extremity Exercise Protocols in Children With Cerebral Palsy

NCT01086670
View directory record Official record
Conditions
Cerebral Palsy, Children, Adolescents
Interventions
Physical Exercise
Other
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
5 Years to 17 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 28, 2022 · Synced Sep 2, 2026, 9:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise-induced Changes in Exosomes

NCT05616234
View directory record Official record
Conditions
Exosomes, Connective Tissue, Exercise
Interventions
Resistance Exercise
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 35 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jun 14, 2023 · Synced Sep 2, 2026, 9:19 PM EDT