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ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:08 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 193–216 of 497 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Leg Training Clear all
Withdrawn Not applicable Interventional

Bilateral Versus Unilateral Strength Training After ACLR

NCT06032247
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries, Atrophy, Muscular, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
Interventions
Resistance exercise program- UL, Resistance exercise program- BL
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 27, 2023 · Synced Oct 20, 2026, 2:08 AM EDT
Recruiting Not applicable Interventional

Rapid Rehabilitation to Treat Lower Extremity Trauma

NCT05225792
View directory record Official record
Conditions
Lower Limb Trauma
Interventions
Promis Physical Function Questionnaire, L Test, Narrowing Beam Walking Test, PEQ-A
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 20, 2026, 2:08 AM EDT
Not listed Not applicable Interventional

Telehealth and Onsite Maintenance Exercise in Chronic Lung Disease

NCT06304207
View directory record Official record
Conditions
Copd, COPD Exacerbation, COPD Bronchitis, Emphysema or COPD, Chronic Lung Disease, Pulmonary Fibrosis, Interstitial Lung Disease, Bronchiectasis, Chronic Asthma, Chronic Asthmatic Bronchitis
Interventions
Onsite Maintenance Exercise Training, Telehealth Maintenance Exercise
Combination Product
Lead sponsor
MGH Institute of Health Professions
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Oct 20, 2026, 2:08 AM EDT
Completed No phase listed Observational

Sleep Disorders of Patients With Diseases of the Nervous System

NCT00001664
View directory record Official record
Conditions
Hypersomnia, Narcolepsy, Nervous System Disease, Sleep Disorder
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
5 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 20, 2026, 2:08 AM EDT
Completed Not applicable Interventional

Post-stroke Perturbation Training

NCT04855032
View directory record Official record
Conditions
Stroke
Interventions
Reactive Perturbations, Proactive Perturbations
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 20, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Type 2 Diabetes and Exercise Function in Single Leg Exercises

NCT01793909
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Single Leg Exercise Training
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 70 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Oct 20, 2026, 2:08 AM EDT
Terminated Phase 3 Interventional Results available

Pulmonary Rehabilitation Before Lung Cancer Resection

NCT02887521
View directory record Official record
Conditions
Non-small Cell Lung Cancer (NSCLC), Chronic Obstructive Pulmonary Disease (COPD)
Interventions
education, rehabilitation, pedometer, surgery
Other · Procedure · Device
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
6
States / cities
Jacksonville, Florida • Chicago, Illinois • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Oct 20, 2026, 2:08 AM EDT
Completed Not applicable Interventional

Impact of Exercise in Parkinson's Disease

NCT03495193
View directory record Official record
Conditions
Parkinson Disease
Interventions
Exercise training, Sleep hygiene
Other · Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
45 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 26, 2019 · Synced Oct 20, 2026, 2:08 AM EDT
Recruiting Not applicable Interventional

Zesty Exercise System for Therapeutic Engagement

NCT07382674
View directory record Official record
Conditions
Parkinson Disease
Interventions
ZEST-E Robot-Assisted Exercise Program
Device
Lead sponsor
Emory University
Other
Eligibility
40 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 20, 2026, 2:08 AM EDT
Completed Not applicable Interventional

Skeletal Muscle Hypertrophy and Cardio-Metabolic Benefits After Spinal Cord Injury

NCT02660073
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
NMES+FES, Control+FES
Device
Lead sponsor
United States Department of Defense
Federal
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
3
States / cities
The Bronx, New York • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Oct 20, 2026, 2:08 AM EDT
Completed Not applicable Interventional Results available

Spinal Cord Stimulation to Augment Activity Based Therapy

NCT03240601
View directory record Official record
Conditions
Transcutaneous Spinal Stimulation, Walking, Spasticity, Human, Spinal Cord Injuries
Interventions
Transcutaneous spinal stimulation
Device
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Oct 20, 2026, 2:08 AM EDT
Recruiting Not applicable Interventional

Assessment of Neural Signals for the Control of Assistive Devices

NCT06533969
View directory record Official record
Conditions
Spinal Cord Injury (SCI), Initial Encounter
Interventions
Epidural Spinal Cord Stimulation, Electrocorticographic, Electroencephalographic
Procedure · Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 20, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving the Anabolic Action of Plant-based Foods Using Complementary Proteins

NCT06781723
View directory record Official record
Conditions
Health, Recreational Activities, Muscle Protein Synthetic Response to Protein, Muscle Protein Synthesis
Interventions
Resistance Exercise, Isolated Mixture, Rice and Beans
Behavioral · Dietary Supplement · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 35 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 20, 2026, 2:08 AM EDT
Not listed Not applicable Interventional

Remote Balance Training for Individuals With Dementia

NCT05558215
View directory record Official record
Conditions
Dementia
Interventions
Otago Exercise Program
Other
Lead sponsor
Marymount University
Other
Eligibility
60 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 14, 2023 · Synced Oct 20, 2026, 2:08 AM EDT
Completed Not applicable Interventional

Metabolic Health in Individuals With Spinal Cord Injury (SCI)

NCT03204240
View directory record Official record
Conditions
Spinal Cord Injuries, Skeletal Muscle Atrophy, Metabolic Disease
Interventions
Neuromuscular electrical stimulation
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Oct 20, 2026, 2:08 AM EDT
Recruiting Not applicable Interventional

Multisite Transspinal Stimulation for Augmenting Recovery in Spinal Cord Injury

NCT07204184
View directory record Official record
Conditions
Spinal Cord Injuries (Complete and Incomplete)
Interventions
Multisite transspinal stimulation at rest, Multisite transspinal stimulation during robotic gait training
Device
Lead sponsor
Maria Knikou, PT, MBA, PhD
Other
Eligibility
18 Years to 70 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 20, 2026, 2:08 AM EDT
Completed Not applicable Interventional

Intensive Home-based Bimanual and Lower-limb Training in Young Children With Hemiplegia

NCT02299284
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Intensive Home-based Bimanual and Lower-limb Training in Young Children With Hemiplegia
Other
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
2 Years to 12 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Oct 20, 2026, 2:08 AM EDT
Completed No phase listed Observational

Clinical Correlates of Pressure Pain Thresholds in Back and Leg Pain

NCT06653920
View directory record Official record
Conditions
Segmental Dysfunction of the Lumbar Spine, Back Pain, Leg Pain
Interventions
Chiropractic, Exercise, Cryotherapy, Spinalator
Other · Device
Lead sponsor
Leach Chiropractic Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Starkville, Mississippi
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Oct 20, 2026, 2:08 AM EDT
Not yet recruiting Early Phase 1 Interventional

Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors

NCT05326633
View directory record Official record
Conditions
Critical Illness, Sarcopenia, ICU Acquired Weakness
Interventions
MRP and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)
Combination Product
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
60 Years to 99 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 20, 2026, 2:08 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Adjuvant Nitrate to Boost Exercise-induced Health Benefits in Older Adults

NCT07572266
View directory record Official record
Conditions
Aging, Aging Well, Healthy Aging
Interventions
Nitrate enriched beetroot juice, Nitrate depleted beetroot juice, 12 week of combined exercise training
Dietary Supplement · Other
Lead sponsor
Florida Institute for Human and Machine Cognition
Other
Eligibility
60 Years and older
Enrollment
226 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Pensacola, Florida
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 20, 2026, 2:08 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

FIT Exercise in 30d of ULLS-induced Muscle Disuse

NCT06631053
View directory record Official record
Conditions
Muscle Atrophy, Muscle Weakness
Interventions
velocity-based FIT (VBFIT), No Exercise
Other
Lead sponsor
Lance Bollinger
Other
Eligibility
35 Years to 45 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 24, 2025 · Synced Oct 20, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Motor Function After Spinal Cord Injury

NCT01915095
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
rTMS, Sham rTMS, Training, Motor Task
Device · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 85 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
3
States / cities
Miami, Florida • Hines, Illinois • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2021 · Synced Oct 20, 2026, 2:08 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effects of Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients

NCT05876923
View directory record Official record
Conditions
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Indolent Non-hodgkin Lymphoma
Interventions
Biospecimen Collection, Cardiopulmonary Exercise Testing, Dual X-ray Absorptiometry, Electronic Health Record Review, Exercise Intervention, Physical Examination, Questionnaire Administration, Spirometry, Physical Performance Testing, Best Practice
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
2
States / cities
Scottsdale, Arizona • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 20, 2026, 2:08 AM EDT
Completed Not applicable Interventional Results available

Acute Exercise Effects in Obese Pregnancy

NCT03750695
View directory record Official record
Conditions
Pregnancy Complications, Obesity, Pre-Eclampsia, Gestational Diabetes
Interventions
Resistance exercise, Aerobic Exercise, Rest
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 16, 2021 · Synced Oct 20, 2026, 2:08 AM EDT