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ClinicalTrials.gov public records Last synced Oct 22, 2026, 7:21 AM EDT

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Showing 241–264 of 603 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Leg exercise Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Type 2 Diabetes and Exercise Function in Single Leg Exercises

NCT01793909
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Single Leg Exercise Training
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 70 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional

BFRT for Severe Lower Extremity Muscle Atrophy

NCT04357184
View directory record Official record
Conditions
Severe Muscle Atrophy, Muscle Weakness
Interventions
Blood flow restriction training
Other
Lead sponsor
Cincinnati Sportsmedicine Research and Education Foundation
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 16, 2022 · Synced Oct 22, 2026, 7:21 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Neural Mechanism of Aldosterone-induced Insulin Resistance

NCT02102243
View directory record Official record
Conditions
Hypertension
Interventions
DEFINITY® infusion, Human Recombinant Regular Insulin infusion, Dextrose infusion, Flow mediated vasodilation, Endothelial cell collection, Microvascular perfusion assessment using Definity, Microneurography
Drug · Procedure
Lead sponsor
Wanpen Vongpatanasin
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 15, 2023 · Synced Oct 22, 2026, 7:21 AM EDT
Recruiting Not applicable Interventional

Home-Based Leg Dexterity Trainer for Management of Knee Osteoarthritis

NCT07397806
View directory record Official record
Conditions
Osteo Arthritis of the Knee
Interventions
Lex Dexterity Trainer, Wobble Board
Device
Lead sponsor
Steadman Philippon Research Institute
Other
Eligibility
40 Years to 85 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Vail, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension

NCT01996449
View directory record Official record
Conditions
Hypertension
Interventions
Eplerenone, Amlodipine, Microneurography, Rhythmic handgrip exercise, Sustained hand grip, Forearm blood flow, Arm cycling exercise, Cold Pressor test
Drug · Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 18, 2022 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional

Aerobic and Strengthening Exercise for Acute Leukemia

NCT00766311
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia
Interventions
Gross Motor Function, Knee extension strength, Hand grip strength, Flexibility, Ankle range of motion, Aerobic capacity, Body composition and vital signs
Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
5 Years to 10 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
4
States / cities
Portland, Oregon • Philadelphia, Pennsylvania • Memphis, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 9, 2012 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Acute Effects of an Isometric Loading Intervention on Lower Extremity Landing Biomechanics in Individuals With Patellar Tendinopathy

NCT03262181
View directory record Official record
Conditions
Tendinopathy
Interventions
Isometric Exercise, Sham Transcutaneous Electrical Nerve Stimulation
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
15 Years to 28 Years · Male only
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 19, 2019 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Results available

Reducing Falls With RENEW in Older Adults Who Have Fallen

NCT01080196
View directory record Official record
Conditions
Muscle Atrophy, Physical Deconditioning
Interventions
RENEW
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
65 Years to 95 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Training Induced Muscle Exosome Release

NCT04500769
View directory record Official record
Conditions
Metabolism
Interventions
Acute Resistance Exercise
Behavioral
Lead sponsor
Yuan Wen
Other
Eligibility
18 Years to 30 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessment of Efficacy of Low Intensity Resistance Training in Women at Risk for Symptomatic Knee Osteoarthritis

NCT01440972
View directory record Official record
Conditions
Knee Osteoarthritis, Symptomatic Knee Osteoarthritis
Interventions
partial blood flow restriction (PBFR), low intensity resistance training
Other
Lead sponsor
University of Iowa
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 5, 2016 · Synced Oct 22, 2026, 7:21 AM EDT
Recruiting Not applicable Interventional

Nutrition and Exercise Interventions for Androgen Deprivation Therapy-Induced Obese Frailty in Elderly and Non-Elderly Survivors of Advanced Prostate Cancer

NCT03880422
View directory record Official record
Conditions
Cancer Survivor, Obesity, Overweight, Prostate Adenocarcinoma, Stage A Prostate Cancer, Stage B Prostate Cancer, Stage C Prostate Cancer, Stage D Prostate Cancer, Stage I Prostate Cancer, Stage II Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer, Stage IIC Prostate Cancer, Stage III Prostate Cancer, Stage IIIA Prostate Cancer, Stage IIIB Prostate Cancer, Stage IIIC Prostate Cancer, Stage IV Prostate Cancer, Stage IVA Prostate Cancer, Stage IVB Prostate Cancer
Interventions
Dietary Intervention, Educational Intervention, Exercise Intervention, Quality-of-Life Assessment, Survey Administration
Dietary Supplement · Other · Behavioral
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of Blood Flow Restriction During Aerobic Cycling

NCT04808869
View directory record Official record
Conditions
Exercise Intervention
Interventions
Exercise
Other
Lead sponsor
University of the Incarnate Word
Other
Eligibility
18 Years to 35 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2023 · Synced Oct 22, 2026, 7:21 AM EDT
Recruiting Not applicable Interventional

Interventions to Enhance Quadriceps Output After ACLR

NCT07674784
View directory record Official record
Conditions
ACL
Interventions
NMES, Vibration
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Topical Cannabidiol Cream and Post-exercise Recovery

NCT05044936
View directory record Official record
Conditions
Muscle Damage
Interventions
Cannabidiol Oil, Resistance Exercise
Drug · Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 17, 2023 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional

Strength Training and Medication Effects in Parkinson Disease Effects on Hypokinesia in Parkinson Disease

NCT00665184
View directory record Official record
Conditions
Parkinson Disease
Interventions
Resistance Exercise via Negative Eccentric Work, Standard care exercise training
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
40 Years to 90 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 21, 2011 · Synced Oct 22, 2026, 7:21 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

: Vascular Function in Health and Disease

NCT02966665
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Pulmonary Artery Hypertension, Heart Failure, Hypertension
Interventions
Maximum Exercise Tests, BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate, BQ-123, Fexofenadine, Ranitidine, Angiotensin-II, Valsartan, Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine, BQ-123, MitoQ, BH4
Other · Drug
Lead sponsor
D. Walter Wray
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2030
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 22, 2026, 7:21 AM EDT
Withdrawn Not applicable Interventional

Resistance Training Intervention to Promote Lean Mass in Youth With IBD

NCT04017637
View directory record Official record
Conditions
Inflammatory Bowel Disease
Interventions
Resistance Training
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
14 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 2, 2020 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional

Yoga Versus Exercises for Managing OA

NCT02525341
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Hatha yoga, Aerobic and strengthening exercises, General education
Other
Lead sponsor
University of Minnesota
Other
Eligibility
60 Years to 100 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 7, 2019 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Results available

Spinal Cord Injury Exercise and Nutrition Conceptual Engagement

NCT03495986
View directory record Official record
Conditions
Spinal Cord Injuries, Metabolic Syndrome, Dietary Modification, Paraplegia, Tetraplegia
Interventions
Functional Electrical Stimulation Leg Cycle Ergometry, Diet
Device · Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 22, 2026, 7:21 AM EDT
Terminated Not applicable Interventional Results available

Flexitouch Treatment for Venous Ulcers

NCT00847002
View directory record Official record
Conditions
Venous Ulcer
Interventions
Standard Wound Care, Flexitouch System with Standard Wound Care
Device
Lead sponsor
Tactile Systems Technology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Minneapolis, Minnesota • College Station, Texas
Source: ClinicalTrials.gov public record
Updated Feb 12, 2020 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional

Functional and Structural Imaging and Motor Control in Spinocerebellar Ataxia

NCT02488031
View directory record Official record
Conditions
Spinocerebellar Ataxia
Interventions
Error-reduction, International Cooperative Ataxia Rating Scale, Scale for the Assessment and Rating of Ataxia, Beck Depression Inventory, 2nd Ed, Stroop, Purdue Pegboard, Brief Test of Attention, 6-minute Walk, Hand Grip Dynamometer, Montreal Cognitive Assessment, Physical Performance Function, Biomechanical Assessments of Dysmetria, Neurophysiological assessment of brain activity, Biomechanical gait analysis
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 85 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 13, 2019 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Results available

Uphill Walking as Exercise for COPD Patients

NCT04026529
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
walking on incline or walking at increasing speed
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 30, 2024 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional

Effect of a Boxing Program on People With Parkinson Disease

NCT04781842
View directory record Official record
Conditions
Parkinson Disease
Interventions
Boxing exercise program
Other
Lead sponsor
Husson University
Other
Eligibility
Not listed
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bangor, Maine
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Oct 22, 2026, 7:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High-speed Power Training in Older Adults With Knee Osteoarthritis (OA)

NCT01328340
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
High-speed power training, Slow-speed strength training
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
55 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 4, 2016 · Synced Oct 22, 2026, 7:21 AM EDT