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ClinicalTrials.gov public records Last synced Oct 22, 2026, 6:29 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 361–384 of 603 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Leg exercise Clear all
Completed Not applicable Interventional

Physical Therapy to Treat Chronic Pain in Survivors of Trauma

NCT03933189
View directory record Official record
Conditions
Chronic Pain, Disability Physical
Interventions
Physical Therapy
Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
South Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Oct 22, 2026, 6:29 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Venous Compression in Fontan

NCT07220226
View directory record Official record
Conditions
Single-ventricle, Fontan Circulation
Interventions
Lower extremity compression garments, Without compression garments
Device · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 22, 2026, 6:29 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Pre- and Post-neuromusculoskeletal Injury Risk Evaluation for Return-to-Duty Enhancement

NCT05111925
View directory record Official record
Conditions
Musculoskeletal Injuries
Interventions
PREPARE Initial Clinical Assessment - Pilot (two iterations), PREPARE Initial Clinical Assessment - Pre-Injury (one iteration), PREPARE Initial Clinical Assessment - Post-Injury (up to three iterations), PREPARE Optimized Clinical Assessment
Other
Lead sponsor
Womack Army Medical Center
Federal
Eligibility
18 Years to 44 Years
Enrollment
2,690 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Liberty, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Characterizing Clinical and Biomechanical Contributions to Function Following ACL Reconstruction

NCT03132987
View directory record Official record
Conditions
ACL Tears
Interventions
Progressive strengthening program
Other
Lead sponsor
Creighton University
Other
Eligibility
14 Years to 35 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 17, 2017 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Phase 2 Interventional Results available

Study of LLG783 in Patients With Peripheral Artery Disease (PAD) and Intermittent Claudication

NCT03194776
View directory record Official record
Conditions
Peripheral Artery Disease (PAD); Intermittent Claudication
Interventions
LLG783, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
40 Years to 85 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Jacksonville, Florida • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Low Intensity Resistance Training With Partial Blood Flow Restriction for Quadriceps Strengthening

NCT01311206
View directory record Official record
Conditions
Knee Osteoarthritis, Symptomatic Knee Osteoarthritis
Interventions
partial blood flow restriction, Low intensity exercise without partial blood flow restriction
Other
Lead sponsor
University of Iowa
Other
Eligibility
45 Years to 60 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 28, 2011 · Synced Oct 22, 2026, 6:29 PM EDT
Recruiting Not applicable Interventional

Reducing Fatigue in People With Multiple Sclerosis by Treatment With TENS

NCT05500963
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Transcutaneous electrical nerve stimulation
Device
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Oct 22, 2026, 6:29 PM EDT
Enrolling by invitation Early Phase 1 Interventional

Exercise Rehabilitation in Patients With Severe Cardiopulmonary Dysfunction on Extracorporeal Life Support

NCT06792617
View directory record Official record
Conditions
ExtraCorporeal Membrane Oxygenation (ECMO), Cardiopulmonary Function, Rehabilitation
Interventions
Mobility (Central or Femoral Cannulation), Resistance Training
Other
Lead sponsor
Institute for Extracorporeal Life Support
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 24, 2025 · Synced Oct 22, 2026, 6:29 PM EDT
Withdrawn Phase 2 Interventional

A Study to Evaluate the Efficacy of Somatropin in the Treatment of Patellar Tendinopathy

NCT02597660
View directory record Official record
Conditions
Tendinopathy
Interventions
Somatropin, Bacteriostatic saline, Progressive exercise program, Patellar tendon biopsy
Drug · Other · Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Not applicable Interventional Results available

Effect of Mirror Therapy on Lower Extremity Motor Control and Gait in Patients With Stroke

NCT01574079
View directory record Official record
Conditions
Stroke
Interventions
Traditional Physical Therapy, Physical Therapy plus Mirror Therapy
Other
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Sep 11, 2014 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise and Endocannabinoids for Brain and Mental Health

NCT06808490
View directory record Official record
Conditions
Children, Adolescents
Interventions
Moderate Intensity Exercise, Light Intensity Stretching, Seated Meditation
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
9 Years to 17 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Community-based Intervention Effects on Older Adults' Physical Activity

NCT03326141
View directory record Official record
Conditions
Exercise, Physical Activity, Accidental Fall, Motivation, Older Adults
Interventions
Otago Exercise Program, Physical activity monitors (e.g., Fitbit), Interpersonal Behavior Change Strategies, Intrapersonal Behavior Change Strategies, Information about Health and Wellness
Behavioral · Device · Other
Lead sponsor
University of Minnesota
Other
Eligibility
70 Years and older
Enrollment
309 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Not applicable Interventional

Relationships Between Exercise and Emotion Regulation on Physical Activity in Frail Older Adults

NCT03514160
View directory record Official record
Conditions
Mobility Limitation, Sedentary Lifestyle, Older Adults
Interventions
Group exercise
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
60 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Oct 22, 2026, 6:29 PM EDT
Terminated Not applicable Interventional Results available

Effect of Electromyographic Biofeedback on Quadriceps Neuromuscular Function in Patients With Quadriceps Inhibition

NCT02095223
View directory record Official record
Conditions
Knee Injuries
Interventions
Electromyographic Biofeedback, Traditional Exercise
Device · Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 40 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 22, 2026, 6:29 PM EDT
Recruiting Not applicable Interventional

REVASC-PAD: REstricted VASCular Exercise for Peripheral Arterial Disease - A Feasibility Study at University of Tennessee Medical Center

NCT07223437
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Blood Flow Restriction Cuff System, Low-load Resistance Training, High-load Resistance Training
Behavioral
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Not applicable Interventional

Aerobic and Strengthening Exercise for Acute Leukemia

NCT00766311
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia
Interventions
Gross Motor Function, Knee extension strength, Hand grip strength, Flexibility, Ankle range of motion, Aerobic capacity, Body composition and vital signs
Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
5 Years to 10 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
4
States / cities
Portland, Oregon • Philadelphia, Pennsylvania • Memphis, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 9, 2012 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Acute Effects of an Isometric Loading Intervention on Lower Extremity Landing Biomechanics in Individuals With Patellar Tendinopathy

NCT03262181
View directory record Official record
Conditions
Tendinopathy
Interventions
Isometric Exercise, Sham Transcutaneous Electrical Nerve Stimulation
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
15 Years to 28 Years · Male only
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 19, 2019 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Not applicable Interventional

Inspiration Point-A Digital Pulmonary Rehabilitation Tool Management Interventions

NCT03801330
View directory record Official record
Conditions
COPD
Interventions
Usual Care Pulmonary Rehabilitation Program, Pulmonary Rehabilitation Software-Based Home Program
Other
Lead sponsor
Blue Marble Rehab Inc
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
4
States / cities
Charlotte, North Carolina • Durham, North Carolina • Dawes, West Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2023 · Synced Oct 22, 2026, 6:29 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Multidimensional Predictive Modeling to Understand Mechanisms of Exercise Response Heterogeneity in Older Adults (M3AX)

NCT06507189
View directory record Official record
Conditions
Aging, Aging Well
Interventions
Combined endurance and resistance training
Other
Lead sponsor
Florida Institute for Human and Machine Cognition
Other
Eligibility
60 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Pensacola, Florida • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Not applicable Interventional Results available

Nutrition and Aerobic Exercise in Chronic Stroke

NCT02043574
View directory record Official record
Conditions
Stroke
Interventions
Treadmill Exercise, Stretching (control)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
Baltimore, Maryland • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 31, 2020 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

The Role of Arnica on Muscle Pain Following Eccentric Exercise

NCT00504010
View directory record Official record
Conditions
Muscles, Exercise, Arnica
Interventions
Arnica Montana, placebo cream
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2009 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Muscle Injury Prevention & Rehabilitation in Military Personnel

NCT02077413
View directory record Official record
Conditions
Muscle Injury
Interventions
Healthy Muscle Group, Stretch-Contract Pre-rehabilitation Group, Stretch-Contract Control Group, Muscle Atrophy
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 40 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 17, 2016 · Synced Oct 22, 2026, 6:29 PM EDT
Not listed Not applicable Interventional

Negative Work Exercise for the Treatment of Knee Arthritis

NCT02098096
View directory record Official record
Conditions
Osteoarthritis, Arthritis
Interventions
Negative Work, Stretching
Other
Lead sponsor
Washington D.C. Veterans Affairs Medical Center
Federal
Eligibility
50 Years to 70 Years · Male only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 20, 2018 · Synced Oct 22, 2026, 6:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Training Improves Balance Control

NCT01547988
View directory record Official record
Conditions
Accidental Falls
Interventions
Balance Training Intervention
Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
65 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2003
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 22, 2026, 6:29 PM EDT