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ClinicalTrials.gov public records Last synced Oct 23, 2026, 8:59 AM EDT

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Showing 505–528 of 603 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Leg exercise Clear all
Completed Not applicable Interventional Results available

Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes

NCT03190889
View directory record Official record
Conditions
Rehabilitation, ACL Reconstruction
Interventions
HOME, TNMT
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
13 Years to 30 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
4
States / cities
Flowery Branch, Georgia • Minneapolis, Minnesota • Rochester, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 23, 2026, 8:59 AM EDT
Withdrawn Not applicable Interventional

Dry Needling and Exercise Versus Traditional Physical Therapy for Biceps Tendinitis

NCT04073212
View directory record Official record
Conditions
Bicep Tendinitis, Biceps; Tenosynovitis, Bicipital Tendinitis, Left Shoulder, Bicipital Tendinitis, Right Shoulder, Bicipital Tendinitis, Unspecified Shoulder, Biceps Tendon Disorder
Interventions
Dry Needling, Heavy Slow Load Exercise, Rotator cuff and scapular stabilization exercise program, Soft tissue mobilization
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Aurora, Colorado • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Training With Blood Flow Restriction

NCT05863039
View directory record Official record
Conditions
Healthy
Interventions
Blood flow restriction, Regular training type 1, Regular training type 2
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 50 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Norman, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Phase 2 Interventional Results available

Twice Weekly Steroids and Exercise as Therapy for DMD

NCT04322357
View directory record Official record
Conditions
Duchenne Muscular Dystrophy (DMD)
Interventions
Prednisone, Exercise Training on standard steroid regimen, Exercise training on twice-weekly steroids
Drug · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
5 Years to 9 Years · Male only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional Results available

Impact of Direct Current Electrical Stimulation on Spasticity Levels and Functional Muscle Use in MS

NCT04942938
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Neubie
Device
Lead sponsor
CommonSpirit Health
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Littleton, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 4, 2025 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain

NCT05022121
View directory record Official record
Conditions
Low Back Pain, Sciatica, Back Related Leg Pain, Pain, Chronic, Intervertebral Disc Displacement
Interventions
Supported Biopsychosocial Self-Management (SBSM), Medical Care
Behavioral · Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Minneapolis, Minnesota • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional

Feasibility Study for Enhancing Gait Following Stroke With Implanted Microstimulators

NCT01640041
View directory record Official record
Conditions
Hemiparesis
Interventions
Radio-frequency Microstiumulator
Device
Lead sponsor
The Alfred E. Mann Foundation for Scientific Research
Other
Eligibility
21 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 25, 2017 · Synced Oct 23, 2026, 8:59 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

: Vascular Function in Health and Disease

NCT02966665
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Pulmonary Artery Hypertension, Heart Failure, Hypertension
Interventions
Maximum Exercise Tests, BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate, BQ-123, Fexofenadine, Ranitidine, Angiotensin-II, Valsartan, Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine, BQ-123, MitoQ, BH4
Other · Drug
Lead sponsor
D. Walter Wray
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2030
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 23, 2026, 8:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Does Walking Performance Improve When Veterans With Leg Amputations Are Given Visual Feedback?

NCT03974945
View directory record Official record
Conditions
Amputation
Interventions
Passive-elastic prosthetic foot, Powered ankle-foot prosthesis
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 67 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional

Targeting Balance Confidence to Increase Community Integration in Users of Prostheses

NCT03411148
View directory record Official record
Conditions
Amputation, Physical Activity
Interventions
Weekly exercise sessions with physical therapist and psychologist, Home-based exercises
Behavioral
Lead sponsor
Rosalind Franklin University of Medicine and Science
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
North Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 1, 2022 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inspiring Seniors Toward Exercise Promotion

NCT06364189
View directory record Official record
Conditions
Cognitively Normal Older Adults
Interventions
Music, Exercise
Behavioral
Lead sponsor
University of North Carolina, Greensboro
Other
Eligibility
65 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Atlanta, Georgia • Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Oct 23, 2026, 8:59 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness of the On the Move Group Exercise Program to Improve Mobility in Community-dwelling Older Adults

NCT05126355
View directory record Official record
Conditions
Mobility Limitation
Interventions
On the Move group exercise
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
529 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 23, 2026, 8:59 AM EDT
Recruiting Not applicable Interventional

MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology

NCT06409949
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Walking assessment, QOL Survey, Ankle pressure at rest and after stress, Muscle Oxygen, Serum MitoQ Level, Needle Biopsy
Diagnostic Test · Other · Procedure
Lead sponsor
University of Nebraska
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 23, 2026, 8:59 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Exercise Mode on Cardiac Fat and Function

NCT03297333
View directory record Official record
Conditions
Obesity
Interventions
Resistance training, Aerobic interval training
Other
Lead sponsor
Southern Illinois University Edwardsville
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Edwardsville, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 4, 2021 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional Results available

BCI-FES Therapy for Stroke Rehabilitation

NCT04279067
View directory record Official record
Conditions
Ischemic Stroke, Hemorrhagic Stroke
Interventions
BCI-FES dorsiflexion therapy, Physiotherapy one hour, Physiotherapy two hours
Device · Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 80 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional

Low-Load Blood Flow Restriction on Patients With Multiple Sclerosis

NCT05177952
View directory record Official record
Conditions
Training Study, Multiple Sclerosis, Blood Flow Restriction
Interventions
Blood Flow Restriction, Standard of Care
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Oct 23, 2026, 8:59 AM EDT
Withdrawn Not applicable Interventional

The Effect of Low-Intensity Blood Flow Restriction Therapy on the Management of Acute Ankle Sprains

NCT05596162
View directory record Official record
Conditions
Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree, Musculoskeletal Injury
Interventions
Blood Flow Restriction Therapy, Standard Physical Therapy
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Oct 23, 2026, 8:59 AM EDT
Not listed Not applicable Interventional

Wearable Sensor-based Balance Training for Patients With Knee Osteoarthritis

NCT02620462
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Wearable sensor-based exercise training
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 90 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 17, 2016 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional Results available

Acute Exercise Effects in Obese Pregnancy

NCT03750695
View directory record Official record
Conditions
Pregnancy Complications, Obesity, Pre-Eclampsia, Gestational Diabetes
Interventions
Resistance exercise, Aerobic Exercise, Rest
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 16, 2021 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional

Community Walking Exercise for Patients With Peripheral Artery Disease

NCT02075502
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Exercise therapy, lower extremity ET, peripheral open intervention
Behavioral · Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
40 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Apr 22, 2020 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Phase 3 Interventional Results available

Heartland Osteoporosis Prevention Study

NCT02186600
View directory record Official record
Conditions
Osteopenia
Interventions
Calcium Carbonate, Vitamin D3, Risedronate, Bone-loading exercises
Drug · Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older · Female only
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced Oct 23, 2026, 8:59 AM EDT
Recruiting Not applicable Interventional

The Effect of Cupping on Spasticity and Function of the Lower Extremity During Rehabilitation After Stroke

NCT06653855
View directory record Official record
Conditions
Stroke Gait Rehabilitation
Interventions
Dry Static Cupping, Placebo cupping, Standard physical therapy treatment
Other
Lead sponsor
Scott Getsoian
Industry
Eligibility
30 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Joliet, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 13, 2024 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional

Prevention of Osteoporosis in Breast Cancer Survivors

NCT00567606
View directory record Official record
Conditions
Postmenopausal Osteoporosis
Interventions
Strength/Weight Training & Drug/Supplement, Drug/Supplement only
Other · Combination Product
Lead sponsor
University of Nebraska
Other
Eligibility
35 Years to 75 Years · Female only
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
4
States / cities
Kearney, Nebraska • Lincoln, Nebraska • Omaha, Nebraska + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Oct 23, 2026, 8:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise Rehabilitation in Veterans With PAD

NCT02607046
View directory record Official record
Conditions
Peripheral Arterial Disease, Intermittent Claudication
Interventions
Exercise training, NMES
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 80 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Oct 23, 2026, 8:59 AM EDT