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ClinicalTrials.gov public records Last synced Oct 19, 2026, 5:09 AM EDT

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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Legacy Intervention Clear all
Recruiting Not applicable Interventional

Feeding the Flame, One Day at a Time: Design and Acceptability of a Serious Game to Support Medication Adherence and Education for Pediatric Solid Organ Transplant Patients

NCT07609303
View directory record Official record
Conditions
Solid Organ Transplant
Interventions
Mystic Wizard
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
7 Years to 17 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Phase 3 Interventional Results available

Levodopa-Carbidopa Intestinal Gel Open-Label Study in Advanced Parkinson's Disease

NCT00335153
View directory record Official record
Conditions
Advanced Parkinson's Disease
Interventions
Levodopa-carbidopa intestinal gel, CADD-Legacy® 1400 ambulatory infusion pump, PEG tube, J-tube
Drug · Device
Lead sponsor
AbbVie (prior sponsor, Abbott)
Industry
Eligibility
30 Years and older
Enrollment
354 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
31
States / cities
Birmingham, Alabama • Fountain Valley, California • Los Angeles, California + 25 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2015 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project Legacy Impact Evaluation Study

NCT03366636
View directory record Official record
Conditions
Pregnancy Prevention, Sexual Behavior, Contraception Behavior, Sexually Transmitted Diseases
Interventions
Project Legacy
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
14 Years to 19 Years
Enrollment
571 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
12
States / cities
Boyle Heights, California • Long Beach, California • Los Angeles, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 3, 2024 · Synced Oct 19, 2026, 5:09 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Development of Psychotherapeutic Interventions for Parents Who Lost a Child

NCT02153619
View directory record Official record
Conditions
Parents Who Have Lost a Child
Interventions
Meaning-Centered Grief Therapy (MCGT), Supportive Psychotherapy (SP), questionnaires assessments
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Not listed
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Not applicable Interventional

Digital-storytelling Intervention for Rural-dwelling Children

NCT04665479
View directory record Official record
Conditions
Pediatrics
Interventions
Web-based legacy-making intervention through digital storytelling
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
8 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 27, 2023 · Synced Oct 19, 2026, 5:09 AM EDT
Recruiting No phase listed Observational

LEGACY: Lung Cancer Screening in Individuals With a Lung Cancer Family History-Protocol B

NCT07600801
View directory record Official record
Conditions
Family History of Lung Cancer
Interventions
CT scan, Sybil
Diagnostic Test · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
2,250 participants
Timeline
2026 – 2035
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Not applicable Interventional

Music Therapy Intervention to Reduce Caregiver Distress at the End of Life

NCT03322228
View directory record Official record
Conditions
Quality of Life, Stress, Anxiety, Depression
Interventions
Music Therapy
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Not applicable Interventional Results available

Clinical Efficacy in Relief of Dyspnea by HVNI: Evaluation of New Cannulae Designs

NCT04512781
View directory record Official record
Conditions
Dyspnea, Hypercapnia, Respiratory Insufficiency
Interventions
Control Cannula - Prosoft Cannula - Unicorn Cannula, Control Cannula - Unicorn Cannula - Prosoft Cannula
Device
Lead sponsor
Vapotherm, Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 23, 2024 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Men of African American Legacy Empowering Self

NCT01492530
View directory record Official record
Conditions
HIV
Interventions
Men of African American Legacy Empowering Self, Standard HIV Education & Risk Reduction
Behavioral
Lead sponsor
Charles Drew University of Medicine and Science
Other
Eligibility
18 Years and older · Male only
Enrollment
437 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2014 · Synced Oct 19, 2026, 5:09 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

The CALERIE™ Legacy Study

NCT05651620
View directory record Official record
Conditions
Calorie Restriction
Interventions
Not listed
Lead sponsor
Tufts University
Other
Eligibility
33 Years to 70 Years
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
3
States / cities
Baton Rouge, Louisiana • Boston, Massachusetts • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Not applicable Interventional Results available

Caregiver Outlook: An Intervention to Improve Caregiving in Serious Illness

NCT01672294
View directory record Official record
Conditions
Heart Failure, Pulmonary Disease, Cancer
Interventions
Preparation and life completion, Attention Control
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
286 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Oct 19, 2026, 5:09 AM EDT
Not yet recruiting Not applicable Interventional

LEGACY: Lung Cancer Screening in Individuals With a Lung Cancer Family History-Protocol A

NCT07685028
View directory record Official record
Conditions
Family History of Lung Cancer
Interventions
CT scan, Sybil
Diagnostic Test · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2035
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Not applicable Interventional Results available

Outlook Quality of Life Intervention Study

NCT01044290
View directory record Official record
Conditions
Cancer, Congestive Heart Failure (CHF), Chronic Obstructive Pulmonary Disease (COPD), End Stage Renal Disease (ESRD)
Interventions
Life Completion, Attention Control
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 95 Years
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 20, 2015 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adherence to Colon Cancer Screening (ACCS)

NCT02112747
View directory record Official record
Conditions
Colon Cancer, Rectal Cancer
Interventions
Patient Navigator
Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
25 Years to 75 Years
Enrollment
1,900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 19, 2026, 5:09 AM EDT
Active, not recruiting Not applicable Interventional

CHOICES3: Sickle Cell Disease Parenting CHOICES

NCT05292781
View directory record Official record
Conditions
Sickle Cell Disease, Sickle Cell Trait
Interventions
CHOICES, eBook
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 45 Years
Enrollment
506 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

EaseAlert: Tactile Firefighter Alerting System

NCT05641194
View directory record Official record
Conditions
Heart Rate, Sleep Habit, Sleep
Interventions
Legacy Alerting System, Intervention 2: EaseAlert Standalone
Device
Lead sponsor
Embry-Riddle Aeronautical University
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Blue Springs, Missouri • Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Phase 3 Interventional

Randomized Controlled Trial of Group Psychotherapy Interventions for Cancer Patients

NCT00494910
View directory record Official record
Conditions
Palliative Care
Interventions
Meaning Centered Group Psychotherapy, Supportive Group Psychotherapy
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years and older
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Not applicable Interventional

Outlook: An Intervention to Improve Quality of Life in Serious Illness

NCT00939146
View directory record Official record
Conditions
Neoplasms, Pulmonary Disease, Chronic Obstructive, Heart Failure, Renal Disease
Interventions
Outlook Attention Control, Outlook Intervention
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 7, 2014 · Synced Oct 19, 2026, 5:09 AM EDT
Withdrawn No phase listed Observational

Impact of COVID-19 on the Incidence, Characteristics, Management and Outcome of Sepsis

NCT04698382
View directory record Official record
Conditions
Sepsis, Septic Shock
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 22, 2024 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Females of African American Legacy Empowering Self (FemAALES)

NCT02189876
View directory record Official record
Conditions
HIV
Interventions
Standard of Care, FemAALES
Behavioral
Lead sponsor
Charles Drew University of Medicine and Science
Other
Eligibility
18 Years to 54 Years · Female only
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2018 · Synced Oct 19, 2026, 5:09 AM EDT
Enrolling by invitation Not applicable Interventional

Promoting Nutrition Security and Chronic Disease Management Through a Produce Prescription Program

NCT07117201
View directory record Official record
Conditions
Dietary Intervention, Produce Prescription, Chronic Disease Management, Social Needs Screening
Interventions
Culturally Tailored Cooking Classes, Prescription Produce Plan
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 19, 2026, 5:09 AM EDT
Active, not recruiting Not applicable Interventional

Group Interventions for Breast Cancer Survivors

NCT01775085
View directory record Official record
Conditions
Breast Cancer Survivor
Interventions
manualized group intervention, standardized, manualized group intervention
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2027
U.S. locations
2
States / cities
Commack, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 19, 2026, 5:09 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Lombardi Comprehensive Cancer Center/Legacy Pilot Study to Reduce Adverse Smoking Outcomes in the Context of Lung Cancer Screening

NCT02267096
View directory record Official record
Conditions
Smoking, Lung Cancer
Interventions
Telephone Counseling, Minimal Treatment
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
55 Years to 80 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Burlington, Massachusetts • Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 19, 2016 · Synced Oct 19, 2026, 5:09 AM EDT
Not yet recruiting Not applicable Interventional

Brighter Bites/Legacy Produce Rx Program

NCT06407284
View directory record Official record
Conditions
Child Obesity
Interventions
Produce Prescription Group, Control Group
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
12 Years to 17 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 10, 2025 · Synced Oct 19, 2026, 5:09 AM EDT