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Showing 25–42 of 18 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Legacy Intervention Clear all
Not yet recruiting Not applicable Interventional

LEGACY: Lung Cancer Screening in Individuals With a Lung Cancer Family History-Protocol A

NCT07685028
View directory record Official record
Conditions
Family History of Lung Cancer
Interventions
CT scan, Sybil
Diagnostic Test · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2035
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 17, 2026, 9:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project Legacy Impact Evaluation Study

NCT03366636
View directory record Official record
Conditions
Pregnancy Prevention, Sexual Behavior, Contraception Behavior, Sexually Transmitted Diseases
Interventions
Project Legacy
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
14 Years to 19 Years
Enrollment
571 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
12
States / cities
Boyle Heights, California • Long Beach, California • Los Angeles, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Sep 17, 2026, 9:49 PM EDT
Withdrawn No phase listed Observational

Impact of COVID-19 on the Incidence, Characteristics, Management and Outcome of Sepsis

NCT04698382
View directory record Official record
Conditions
Sepsis, Septic Shock
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced Sep 17, 2026, 9:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

DNA Variations in the Gene in Young Patients With Wilms' Tumor

NCT00088803
View directory record Official record
Conditions
Kidney Cancer
Interventions
molecular genetic technique, polymerase chain reaction, polymorphism analysis
Genetic
Lead sponsor
Children's Oncology Group
Network
Eligibility
Up to 18 Years
Enrollment
471 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2004
U.S. locations
205
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 150 more
Source: ClinicalTrials.gov public record
Updated May 18, 2016 · Synced Sep 17, 2026, 9:49 PM EDT
Completed Phase 3 Interventional Results available

Study of Efficacy, Safety and Tolerability of Levodopa-Carbidopa Intestinal Gel in Levodopa-Responsive Parkinson's Subjects

NCT00660387
View directory record Official record
Conditions
Advanced Parkinson's Disease
Interventions
Levodopa carbidopa intestinal gel (LCIG), Placebo Gel, Levodopa-carbidopa (LC) oral encapsulated immediate release (IR) tablets, Placebo (PBO) oral capsules, CADD-Legacy® 1400 ambulatory infusion pump, PEG tube, J-tube
Drug · Device
Lead sponsor
AbbVie (prior sponsor, Abbott)
Industry
Eligibility
30 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
11
States / cities
Birmingham, Alabama • Fountain Valley, California • Oceanside, California + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2015 · Synced Sep 17, 2026, 9:49 PM EDT
Completed Not applicable Interventional

Rheos System for the Treatment of HFpEF Heart Failure

NCT00957073
View directory record Official record
Conditions
Heart Failure
Interventions
Rheos® system
Device
Lead sponsor
CVRx, Inc.
Industry
Eligibility
21 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2021
U.S. locations
22
States / cities
Mobile, Alabama • Inglewood, California • Los Angeles, California + 18 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 17, 2026, 9:49 PM EDT
Recruiting No phase listed Observational

LEGACY: Lung Cancer Screening in Individuals With a Lung Cancer Family History-Protocol B

NCT07600801
View directory record Official record
Conditions
Family History of Lung Cancer
Interventions
CT scan, Sybil
Diagnostic Test · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
2,250 participants
Timeline
2026 – 2035
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 17, 2026, 9:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adherence to Colon Cancer Screening (ACCS)

NCT02112747
View directory record Official record
Conditions
Colon Cancer, Rectal Cancer
Interventions
Patient Navigator
Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
25 Years to 75 Years
Enrollment
1,900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Sep 17, 2026, 9:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PCRC-Supported Legacy Intervention in Pediatric Palliative Care

NCT04059393
View directory record Official record
Conditions
Care Giver, Recurrent Malignant Neoplasm, Refractory Malignant Neoplasm
Interventions
Internet-Based Intervention, Best Practice, Quality-of-Life Assessment, Questionnaire Administration
Other
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
7 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 17, 2026, 9:49 PM EDT
Enrolling by invitation Not applicable Interventional

Promoting Nutrition Security and Chronic Disease Management Through a Produce Prescription Program

NCT07117201
View directory record Official record
Conditions
Dietary Intervention, Produce Prescription, Chronic Disease Management, Social Needs Screening
Interventions
Culturally Tailored Cooking Classes, Prescription Produce Plan
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Sep 17, 2026, 9:49 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Men of African American Legacy Empowering Self

NCT01492530
View directory record Official record
Conditions
HIV
Interventions
Men of African American Legacy Empowering Self, Standard HIV Education & Risk Reduction
Behavioral
Lead sponsor
Charles Drew University of Medicine and Science
Other
Eligibility
18 Years and older · Male only
Enrollment
437 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2014 · Synced Sep 17, 2026, 9:49 PM EDT
Completed Phase 3 Interventional Results available

Safety/Efficacy Study of Levodopa-Carbidopa Intestinal Gel in Parkinson's Subjects

NCT00360568
View directory record Official record
Conditions
Dyskinesias, Parkinson's Disease, Severe Motor Fluctuations
Interventions
Levodopa-carbidopa intestinal gel, CADD-Legacy® 1400 ambulatory infusion pump, PEG tube, J-tube
Drug · Device
Lead sponsor
AbbVie (prior sponsor, Abbott)
Industry
Eligibility
30 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
16
States / cities
Birmingham, Alabama • Fountain Valley, California • Los Angeles, California + 13 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2015 · Synced Sep 17, 2026, 9:49 PM EDT
Completed Phase 3 Interventional

Randomized Controlled Trial of Group Psychotherapy Interventions for Cancer Patients

NCT00494910
View directory record Official record
Conditions
Palliative Care
Interventions
Meaning Centered Group Psychotherapy, Supportive Group Psychotherapy
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years and older
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 10, 2024 · Synced Sep 17, 2026, 9:49 PM EDT
Completed Phase 3 Interventional Results available

Levodopa-Carbidopa Intestinal Gel Open-Label Study in Advanced Parkinson's Disease

NCT00335153
View directory record Official record
Conditions
Advanced Parkinson's Disease
Interventions
Levodopa-carbidopa intestinal gel, CADD-Legacy® 1400 ambulatory infusion pump, PEG tube, J-tube
Drug · Device
Lead sponsor
AbbVie (prior sponsor, Abbott)
Industry
Eligibility
30 Years and older
Enrollment
354 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
31
States / cities
Birmingham, Alabama • Fountain Valley, California • Los Angeles, California + 25 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2015 · Synced Sep 17, 2026, 9:49 PM EDT
Completed Not applicable Interventional

Legacy Intervention Family Enactment (LIFE)

NCT02007564
View directory record Official record
Conditions
Pain, Retention Disorders, Cognitive, Other Chronic Illness, Palliative Care
Interventions
LIFE Intervention
Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
55 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 14, 2014 · Synced Sep 17, 2026, 9:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Females of African American Legacy Empowering Self (FemAALES)

NCT02189876
View directory record Official record
Conditions
HIV
Interventions
Standard of Care, FemAALES
Behavioral
Lead sponsor
Charles Drew University of Medicine and Science
Other
Eligibility
18 Years to 54 Years · Female only
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 2, 2018 · Synced Sep 17, 2026, 9:49 PM EDT
Recruiting Phase 3 Interventional

Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With Non-Curative Malignancies

NCT07290491
View directory record Official record
Conditions
Cancer
Interventions
Chaplain-Provided Spiritual Care, Psychotherapy and Meditation Intervention
Behavioral
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
854 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 17, 2026, 9:49 PM EDT
Completed Not applicable Interventional Results available

Caregiver Outlook: An Intervention to Improve Caregiving in Serious Illness

NCT01672294
View directory record Official record
Conditions
Heart Failure, Pulmonary Disease, Cancer
Interventions
Preparation and life completion, Attention Control
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
286 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 16, 2017 · Synced Sep 17, 2026, 9:49 PM EDT