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ClinicalTrials.gov public records Last synced Oct 3, 2026, 10:56 AM EDT

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Showing 25–48 of 57 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Lens A ( comfilcon A) Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Central Corneal Swelling With Silicone Hydrogel Materials

NCT02328937
View directory record Official record
Conditions
Corneal Swelling
Interventions
etafilcon A, lotrafilcon B, comfilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Wear Experience With a Water Surface Daily Disposable Contact Lens

NCT05102383
View directory record Official record
Conditions
Contact Lens
Interventions
Comfilcon A Toric contact lenses, Verofilcon A for Astigmatism Daily Disposable contact lenses
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Clinical Performance of a Monthly Replacement Silicone Hydrogel Lens

NCT03586167
View directory record Official record
Conditions
Refractive Errors
Interventions
LID014341 contact lenses, Comfilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
4
States / cities
Maitland, Florida • Johns Creek, Georgia • Bloomington, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of a Silicone Hydrogel Daily Wear Monthly Replacement Contact Lens

NCT04422990
View directory record Official record
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
14
States / cities
Los Angeles, California • Novato, California • Oakland, California + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2022 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Long-Term Evaluation of Approved and Investigational Contact Lenses

NCT02625233
View directory record Official record
Conditions
Visual Disorders
Interventions
senofilcon C, comfilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
6
States / cities
Jacksonville, Florida • Longwood, Florida • Bloomington, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Oct 3, 2026, 10:56 AM EDT
Recruiting No phase listed Observational

North American Comfilcon A Clinical Study

NCT06902584
View directory record Official record
Conditions
Astigmatism, Presbyopia, Ametropia
Interventions
comfilcon A Sphere lens, comfilcon A Toric lens, comfilcon A Multifocal lens, comfilcon A Multifocal Toric lens, comfilcon A Energys lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
8 Years to 75 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
4
States / cities
Berkeley, California • Granville, Ohio • College, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses

NCT02719366
View directory record Official record
Conditions
Presbyopia
Interventions
comfilcon A Extended Range test lens, comfilcon A control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
50 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Evaluating Contact Lens Optics

NCT05028790
View directory record Official record
Conditions
Myopia
Interventions
Single vision contact lens, Multifocal contact lens
Device
Lead sponsor
David A Berntsen, OD PhD
Other
Eligibility
18 Years to 39 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Oct 3, 2026, 10:56 AM EDT
Not yet recruiting Not applicable Interventional

Optimization for Toric Contact Lenses

NCT07557030
View directory record Official record
Conditions
Astigmatism, Ametropia
Interventions
Lens 1 ( stenfilcon A ), Lens 2 ( comfilcon A )
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Mucin Balls and Corneal Inflammation Events

NCT01437319
View directory record Official record
Conditions
Corneal Inflammation, Corneal Infiltrative Events
Interventions
lotrafilcon A, comfilcon A, balafilcon A, etafilcon A
Device · Other
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
289 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
3
States / cities
Beachwood, Ohio • Cleveland, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Multi-Center 2-Week Clinical Evaluation of Three Silicone Hydrogel Contact Lenses

NCT01244516
View directory record Official record
Conditions
Myopia
Interventions
galyfilcon A, BC 8.30, lotrafilcon B, BC 8.60, comfilcon A, BC 8.60
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
540 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
35
States / cities
Brea, California • Campbell, California • Cupertino, California + 31 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of a Daily Wear Monthly Replacement Silicone Hydrogel Lens

NCT04178720
View directory record Official record
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
8
States / cities
Longwood, Florida • Maitland, Florida • Orlando, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2021 · Synced Oct 3, 2026, 10:56 AM EDT
Completed No phase listed Observational

Air Optix Extended Wear Contact Lenses

NCT05886881
View directory record Official record
Conditions
Refractive Errors
Interventions
Lotrafilcon B spherical soft contact lenses, Lotrafilcon B spherical soft contact lenses with comfort additive, Lotrafilcon B toric soft contact lenses with comfort additive, Comfilcon A spherical soft contact lenses, Comfilcon A toric soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
505 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
Orlando, Florida • Medina, Minnesota • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Approved and Investigational Contact Lenses

NCT02669095
View directory record Official record
Conditions
Visual Disorder
Interventions
Investigational Contact Lenses (Test), Marketed Contact Lenses (Control)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
4
States / cities
Sarasota, Florida • Winter Park, Florida • Pickens, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2017 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Evaluation of Two Silicone Hydrogel Toric Lens Designs in Habitual Soft Contact Lens Wearers

NCT05933772
View directory record Official record
Conditions
Astigmatism
Interventions
Lens A (comfilcon A toric lens), Lens B (lehfilcon A toric lens)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years to 39 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
3
States / cities
Pittsburg, Kansas • Vestal, New York • Granville, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Dispensing Study for a New Study Lens

NCT02642991
View directory record Official record
Conditions
Myopia
Interventions
Phenacite, comfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Berkeley, California • Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 1, 2020 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Clinical Assessment of a Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lens

NCT04476784
View directory record Official record
Conditions
Myopia
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
5
States / cities
Maitland, Florida • Bloomington, Illinois • Pittsburg, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2021 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Multicenter Dispensing Study of Biofinity Toric Made-To-Order Lenses in Extended Power Ranges

NCT02193178
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
comfilcon A Toric
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Bloomington, Indiana • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Clinical Assessment of Two Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lenses

NCT04980456
View directory record Official record
Conditions
Myopia
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
257 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
14
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2023 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses

NCT02719353
View directory record Official record
Conditions
Presbyopia
Interventions
comfilcon A Extended Range test lens, comfilcon A control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
50 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Oct 3, 2026, 10:56 AM EDT
Completed No phase listed Observational

Air Optix Plus HydraGlyde Multifocal Daily/Extended Wear Contact Lenses

NCT05886894
View directory record Official record
Conditions
Refractive Errors
Interventions
Lotrafilcon B multifocal soft contact lenses, Comfilcon A multifocal soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
8
States / cities
San Diego, California • Jacksonville, Florida • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional

Comprehensive Assessment of Multiple Products (CAMP)

NCT07276347
View directory record Official record
Conditions
Hyperopia, Myopia
Interventions
somofilcon A lens, stenfilcon A lens, fanfilcon A lens, comfilcon A lens, verofilcon A lens, serafilcon A lens, lehfilcon A lens, delefilcon A lens, senofilcon A daily disposable lens, senofilcon A with blue light technology lens, senofilcon A bi-weekly lens, samfilcon A lens, kalilfilcon A lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years to 45 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

One Month Dispensing Study Comparing the Clinical Performance of the Comfilcon A Sphere Lenses Compared to Comfilcon A Asphere Lenses.

NCT02759471
View directory record Official record
Conditions
Myopia
Interventions
comfilcon A sphere lens (control), comfilcon A asphere lens (test)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 34 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
4
States / cities
Whittier, California • Medina, Minnesota • Vestal, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Oct 3, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Clinical Validation Study of Comfilcon A Multifocal Toric Contact Lenses

NCT03417557
View directory record Official record
Conditions
Presbyopia
Interventions
Comfilcon A lens (test), Omafilcon B lens (control)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
40 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Oct 3, 2026, 10:56 AM EDT