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ClinicalTrials.gov public records Last synced Oct 9, 2026, 5:02 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 261 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Letter Intervention Clear all
Recruiting Not applicable Interventional

AI Detection of Incidental Coronary Artery Calcium to Enhance Cardiovascular Disease Prevention

NCT06235112
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Electronic health record-based notification of Nanox.AI Coronary Artery Calcification Assessment
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
40 Years to 75 Years
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Improving Wisely - Polypharmacy

NCT03857100
View directory record Official record
Conditions
Adverse Drug Event
Interventions
Audit and feedback - letter and report
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
Not listed
Enrollment
11,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 23, 2021 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comprehensive Police Fatigue Management Program

NCT00246051
View directory record Official record
Conditions
Sleep Disorders, Sleep Apnea, Obstructive, Restless Legs Syndrome, Sleep Disorders, Circadian Rhythm, Sleep Initiation and Maintenance Disorders
Interventions
Sleep Hygiene Education, Expert-Led Sleep Disorders Screening and Treatment, Online Sleep Disorders Screening
Behavioral · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
683 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 15, 2013 · Synced Oct 9, 2026, 5:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

HealthyTogether: RCT of a Dyadic Weight Management Intervention

NCT06619041
View directory record Official record
Conditions
Obesity, Overweight
Interventions
HealthyTogether
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Interventions to Increase Screening by Breast Cancer Survivors and Their High Risk Female Relatives

NCT01612338
View directory record Official record
Conditions
Breast Cancer, Breast Cancer in Young Women, Breast Cancer in Women With a Strong Family History
Interventions
Targeted, Enhanced Tailored
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 64 Years · Female only
Enrollment
1,290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
2
States / cities
Ann Arbor, Michigan • Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 22, 2019 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Not applicable Interventional Results available

COPD Assessment and Management Bundle Versus Usual Care

NCT01833026
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Spirometry test, Levalbuterol
Device · Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
40 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 24, 2019 · Synced Oct 9, 2026, 5:02 AM EDT
Recruiting No phase listed Observational

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

NCT05589714
View directory record Official record
Conditions
Inherited Retinal Degeneration, Retinitis Pigmentosa
Interventions
Not listed
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
4 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
19
States / cities
Little Rock, Arkansas • Los Angeles, California • San Francisco, California + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Not applicable Interventional Results available

Anticoagulation With Enhanced Gastrointestinal Safety (AEGIS) Trial

NCT05085405
View directory record Official record
Conditions
Upper Gastrointestinal Bleeding
Interventions
Clinician notification, Clinician Notification with Nurse Facilitation, Clinician Notification / Patient Activation, Clinician Notification with Nurse Facilitation / Patient Activation
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 29, 2023 · Synced Oct 9, 2026, 5:02 AM EDT
Recruiting Not applicable Interventional

Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing

NCT06629272
View directory record Official record
Conditions
Hypothyroidism
Interventions
D-THIO (Deprescribing Thyroid Hormone In Older Adults), Enhanced usual care
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
65 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
San Francisco, California • Ann Arbor, Michigan • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 9, 2026, 5:02 AM EDT
Recruiting Not applicable Interventional

Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT)

NCT07290361
View directory record Official record
Conditions
Low Back Pain, Neck Pain
Interventions
Engagement of clinic leadership (System Intervention - Usual Care), Engagement of clinic leadership (System Intervention - STEPPT), Patient Registry (System Intervention - STEPPT), Delivery of Patient Education Materials (System Intervention - Usual Care), Delivery of Patient Education Materials (System Intervention - STEPPT), Referral Specialist Training (System Intervention - Usual Care), Patient Health Navigator Training (System Intervention - STEPPT), Care Navigation (System Intervention - STEPPT), Care navigation audit and feedback (System Intervention - STEPPT), Primary Care Provider training (Provider Intervention - STEPPT), Nurse/Medical Assistant Training (Provider Intervention - STEPPT), Provider feedback on PT referral and adherence (Provider Intervention - STEPPT), Patient education on spine pain condition (Patient Intervention - Usual Care), Patient education on spine pain condition (Patient Intervention - STEPPT), Patient Education on Physical Referral by Providers (Patient Intervention - Usual Care), Patient Education on Physical Referral by Providers (Patient Intervention - STEPPT), Electronic Patient Education on Physical Therapy Referral (Patient Intervention - STEPPT), Patient education on physical therapy referral by Referral Specialist (Patient Intervention - Usual Care), Patient education on physical therapy referral by Patient Health Navigator (Patient Intervention - STEPPT), Care Navigation (System Intervention - Usual Care), Monitoring of PT referral and adherence rates (System Intervention - STEPPT), Monitoring of PT referral and adherence rates (System intervention - Usual Care)
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older
Enrollment
17,587 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Reducing Environmental Tobacco Smoke in Neonatal Intensive Care Unit (NICU) Infants' Homes

NCT00670280
View directory record Official record
Conditions
Infant Environmental Tobacco Smoke Exposure
Interventions
Motivational Interviewing intervention, Usual Care, Usual Care - Reduced Measurement
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
12 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 6, 2016 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With ADRD

NCT04780178
View directory record Official record
Conditions
Anxiety, Caregiver Burden
Interventions
Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults with Alzheimer's Disease and Related Dementias
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
21 Years to 95 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 1, 2022 · Synced Oct 9, 2026, 5:02 AM EDT
Active, not recruiting Not applicable Interventional

Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) Intervention

NCT05677048
View directory record Official record
Conditions
Gynecologic Cancer, Ovary Cancer, Pancreatic Cancer, Breast Cancer, Lynch Syndrome, Hereditary Breast and Ovarian Cancer Syndrome, Colon Cancer, Endometrial Cancer, Uterus Cancer
Interventions
Free genetic testing and counseling group, IGNITE-TX Group, IGNITE-TX and free genetic testing and counseling group
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Effect of Mailed Invites of Choice of Colonoscopy or FIT vs. Mailed FIT Alone on Colorectal Cancer Screening

NCT03414125
View directory record Official record
Conditions
Colorectal Cancer
Interventions
FIT Screening Strategy, Choice Screening Strategy
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years to 63 Years
Enrollment
26,859 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating a Preference-based Intervention for Increasing Colorectal Cancer Screening

NCT00810771
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Standard Information, Preference-tailored Information
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
50 Years to 78 Years
Enrollment
466 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
2
States / cities
Ann Arbor, Michigan • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Not applicable Interventional Results available

Awareness Enhancing Interventions

NCT04683510
View directory record Official record
Conditions
Research Awareness
Interventions
Navigation - Study Specific - Researcher Voice, Navigation - Study Specific - Cancer Survivor Voice, Navigation - Research General - Researcher Voice, Navigation - Research General - Cancer Survivor Voice, Brochure - Study Specific - Researcher Voice, Brochure - Study Specific - Cancer Survivor Voice, Brochure - Research General - Researcher Voice, Brochure - Research General - Cancer Survivor Voice
Other
Lead sponsor
University of Tennessee
Other
Eligibility
50 Years and older
Enrollment
4,451 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Birmingham, Alabama • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 9, 2026, 5:02 AM EDT
Recruiting Not applicable Interventional

The FYI on MRI: A Multilevel Decision Support Intervention for Screening Breast MRI

NCT06892275
View directory record Official record
Conditions
Breast Neoplasm Female, Early Detection of Cancer, Hereditary Breast and Ovarian Cancer Syndrome, Magnetic Resonance Imaging
Interventions
Enhanced Usual Care, Decision Support
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 74 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With Dementia

NCT04338750
View directory record Official record
Conditions
Anxiety, Anxiety Generalized, Anxiety Disorders and Symptoms, Caregiver Burnout
Interventions
Telephone Acceptance and Commitment Therapy Intervention for Caregivers, minimally-Enhanced Usual Care
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Phase 1 Interventional

Smartphone Technology and CBT-GSH in Binge Eaters

NCT02399982
View directory record Official record
Conditions
Binge Eating Disorder, Bulimia Nervosa
Interventions
CBT-GSH, Noom Monitor
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 3, 2016 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Early Phase 1 Interventional Results available

Feasibility of Delivering a Quitline Based Smoking Cessation Intervention in Cancer Patients

NCT01434342
View directory record Official record
Conditions
Lung Cancer, Tobacco Use Disorder, Breast Cancer, Colorectal Cancer, Prostate Cancer
Interventions
Nicotine Replacement Patch
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Oct 9, 2026, 5:02 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

FaCT Trial (Facilitated Cascade Testing Trial)

NCT04613440
View directory record Official record
Conditions
BRCA1 Mutation, BRCA2 Mutation
Interventions
Family Letter (Standard of Care), Educational Video, Mailed Saliva Kit for Genetic Testing, Telephone Counseling
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
524 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
3
States / cities
New York, New York • Durham, North Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhanced E-cigarette Coaching Intervention for Dual Users of Cigarettes and E-cigarettes

NCT03575468
View directory record Official record
Conditions
Smoking Cessation
Interventions
Enhanced E-cigarette Coaching, Quitline treatment as usual
Behavioral
Lead sponsor
Consumer Wellness Solutions
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Oct 9, 2026, 5:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Virtual Patient Advocate for Preconception Care for African American Women

NCT01812824
View directory record Official record
Conditions
Preconception Care
Interventions
Intervention (Virtual Patient Advocate)
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2017 · Synced Oct 9, 2026, 5:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome

NCT07106359
View directory record Official record
Conditions
Cascade Testing, Lynch Syndrome, Decision Making, Colorectal Cancer, Uterine Cancer, Cancer Prevention
Interventions
Information Letter and Booklet, Information Letter
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 9, 2026, 5:02 AM EDT