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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Levonorgestrel IUD Clear all
Completed No phase listed Observational Accepts healthy volunteers Results available

Study on Medical Records of Women Using an Intrauterine Device (IUD) to Analyze the Risks That the IUD Will be Expelled or Perforates the Womb in Relation to Breastfeeding, the Point in Time When the IUD Was Inserted After Childbirth and in Relation to Different Types of IUDs

NCT03754556
View directory record Official record
Conditions
Intrauterine Devices
Interventions
Intrauterine device
Device
Lead sponsor
Bayer
Industry
Eligibility
Up to 50 Years · Female only
Enrollment
326,658 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
4
States / cities
Oakland, California • Pasadena, California • Indianapolis, Indiana + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced Sep 26, 2026, 4:34 PM EDT
Active, not recruiting Phase 2 Interventional Results available

Levonorgestrel-Releasing Intrauterine System in Treating Patients With Complex Atypical Hyperplasia or Grade I Endometrial Cancer

NCT00788671
View directory record Official record
Conditions
Atypical Endometrial Hyperplasia, Stage I Uterine Corpus Cancer AJCC v7, Stage IA Uterine Corpus Cancer AJCC v7, Stage IB Uterine Corpus Cancer AJCC v7, Stage II Uterine Corpus Cancer AJCC v7
Interventions
Laboratory Biomarker Analysis, Levonorgestrel-Releasing Intrauterine System, Quality-of-Life Assessment
Other · Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2027
U.S. locations
7
States / cities
Houston, Texas • Nassau Bay, Texas • Sugar Land, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Sep 26, 2026, 4:34 PM EDT
Completed Phase 2 Interventional Results available

Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients

NCT02035787
View directory record Official record
Conditions
Complex Atypical Hyperplasia, Endometrial Cancer
Interventions
Metformin
Drug
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Sep 26, 2026, 4:34 PM EDT
Completed Not applicable Interventional Results available

Insertion of an Intrauterine Device (IUD) After Medical Abortion

NCT00621543
View directory record Official record
Conditions
Intrauterine Device Expulsion, Medical Abortion, Induced Abortion
Interventions
IUD insertion [Copper T-380A or Levonorgestrel (intrauterine system) IUS]
Device
Lead sponsor
Boston University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
Boston, Massachusetts • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 13, 2011 · Synced Sep 26, 2026, 4:34 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Long-Acting Progestin Contraception and the Vaginal Microbiome

NCT02740998
View directory record Official record
Conditions
Sexually Transmitted Infection
Interventions
Not listed
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 16, 2018 · Synced Sep 26, 2026, 4:34 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Levonorgestrel Contraceptive Intrauterine Systems (LCS) Pearl Index Study

NCT00528112
View directory record Official record
Conditions
Contraception
Interventions
LCS12, LCS16
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 35 Years · Female only
Enrollment
2,885 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
57
States / cities
Mobile, Alabama • Glendale, Arizona • Phoenix, Arizona + 47 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2017 · Synced Sep 26, 2026, 4:34 PM EDT
Completed No phase listed Observational Results available

Same Day Oral EC and Implant Initiation

NCT04678817
View directory record Official record
Conditions
Contraception
Interventions
Etonogestrel contraceptive implant with oral levonorgestrel, Levonorgestrel intrauterine device, Copper T380A intrauterine device
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Salt Lake City, Utah • West Valley City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 14, 2025 · Synced Sep 26, 2026, 4:34 PM EDT
Terminated Not applicable Interventional Results available

Immediate Postplacental IUD Insertion

NCT02169869
View directory record Official record
Conditions
Contraception
Interventions
Mirena, Paragard
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced Sep 26, 2026, 4:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Targeted Video Messaging About Emergency Contraception

NCT03774368
View directory record Official record
Conditions
Contraception
Interventions
Emergency contraception website, Emergency contraception video
Other
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years to 29 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Sep 26, 2026, 4:34 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

'Levonorgestrel IUD Insertion After D&E Procedure

NCT00475228
View directory record Official record
Conditions
Contraceptive Usage
Interventions
Levonorgestrel IUD
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2017 · Synced Sep 26, 2026, 4:34 PM EDT
Completed No phase listed Observational

Study of the Copper IUD or Oral Levonorgestrel and the Levonorgestrel IUD for Women Seeking Emergency Contraception

NCT01963962
View directory record Official record
Conditions
Emergency Contraception
Interventions
Copper IUD, Levonorgestrel IUD
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 7, 2016 · Synced Sep 26, 2026, 4:34 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Safety and Expulsion of Delayed Versus Immediate Postpartum Intrauterine Device Placement

NCT01598662
View directory record Official record
Conditions
Contraception
Interventions
Mirena (levonorgestrel-releasing intrauterine system)
Device
Lead sponsor
University of Louisville
Other
Eligibility
15 Years to 45 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Sep 26, 2026, 4:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mirena Intrauterine System Timing of Insertion: A Randomized Controlled Trial

NCT01272960
View directory record Official record
Conditions
Postpartum Period
Interventions
Post-Placenta Mirena Insertion, Interval Insertion
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 1, 2017 · Synced Sep 26, 2026, 4:34 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Does Skyla Insertion Timing Impact Bleeding?

NCT03074903
View directory record Official record
Conditions
Vaginal Bleeding
Interventions
Intrauterine system
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
3
States / cities
Morristown, New Jersey • Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 12, 2018 · Synced Sep 26, 2026, 4:34 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Postplacental Insertion of Levonorgestrel-releasing Intrauterine System (LNG-IUS) After Cesarean vs. Interval Insertion

NCT00635362
View directory record Official record
Conditions
Healthy
Interventions
Levonorgestrel-releasing intrauterine system (LNG-IUS)
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 26, 2026, 4:34 PM EDT
Completed No phase listed Observational

Duration of Use of Highly Effective Reversible Contraception

NCT02414919
View directory record Official record
Conditions
Pregnancy
Interventions
Mirena (Levonorgestrel IUS, BAY86-5028), ParaGard, Implanon/Nexplanon
Drug
Lead sponsor
Bayer
Industry
Eligibility
15 Years to 44 Years · Female only
Enrollment
13,880 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 15, 2017 · Synced Sep 26, 2026, 4:34 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Evaluation of the Efficacy and Safety of LevoCept

NCT02882191
View directory record Official record
Conditions
Contraception
Interventions
LevoCept
Drug
Lead sponsor
Sebela Women's Health Inc.
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
279 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
16
States / cities
Berkeley, California • Los Angeles, California • Sacramento, California + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 26, 2026, 4:34 PM EDT
Completed Not applicable Interventional Results available

Mirena® IUD's Effect on Fallopian Tube Fimbriae and Ovarian Cortical Inclusion Cyst Cell Proliferation

NCT02477202
View directory record Official record
Conditions
Epithelial Ovarian Cancer
Interventions
Mirena® intra-uterine device (IUD)
Device
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
35 Years to 50 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
6
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Commack, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2023 · Synced Sep 26, 2026, 4:34 PM EDT
Completed No phase listed Observational

Immediate Postpartum Nexplanon Placement in Opioid Dependent Women

NCT02657148
View directory record Official record
Conditions
Opiate Addiction, Pregnancy, Contraceptive Behavior, Sexual Behavior
Interventions
Nexplanon (etonogestrel contraceptive implant), Standard postpartum contraceptive care
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced Sep 26, 2026, 4:34 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Optimization of the ex Vivo Challenge: Reproductive Infections and Contraception

NCT02375425
View directory record Official record
Conditions
HIV
Interventions
no intervention
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
294 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 23, 2018 · Synced Sep 26, 2026, 4:34 PM EDT
Not yet recruiting Phase 3 Interventional Accepts healthy volunteers

Evaluation of the Efficacy, Safety, and Tolerability of LevoCept

NCT04457076
View directory record Official record
Conditions
Contraception, Women at Risk for Pregnancy
Interventions
LevoCept
Drug
Lead sponsor
Sebela Women's Health Inc.
Industry
Eligibility
Up to 45 Years · Female only
Enrollment
1,525 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
27
States / cities
Berkeley, California • Los Angeles, California • Sacramento, California + 20 more
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Sep 26, 2026, 4:34 PM EDT
Completed Phase 4 Interventional Results available

RAPID EC - Rct Assessing Pregnancy With Intrauterine Devices for EC

NCT02175030
View directory record Official record
Conditions
Contraception
Interventions
Copper IUD, Levonorgestrel IUD
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
711 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
6
States / cities
Logan, Utah • Ogden, Utah • Orem, Utah + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Sep 26, 2026, 4:34 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Immediate Postpartum Insertion of Contraceptive Intrauterine Devices

NCT03657602
View directory record Official record
Conditions
Contraception
Interventions
Kyleena Intrauterine System, Mirena Intrauterine System
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Sep 26, 2026, 4:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nitrous Oxide for Pain Management of Intrauterine Device (IUD) Insertion

NCT02391714
View directory record Official record
Conditions
Contraception
Interventions
IUD insertion, Povidone-Iodine, Chlorhexidine, Oxygen, Nitrous oxide
Procedure · Drug · Other
Lead sponsor
University of New Mexico
Other
Eligibility
12 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Sep 26, 2026, 4:34 PM EDT