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Showing 1–24 of 965 matching trials from the live ClinicalTrials.gov search.
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Withdrawn Not applicable Interventional

Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes

NCT03543033
View directory record Official record
Conditions
Lumbar Radiculopathy
Interventions
Corticosteroid injection
Drug
Lead sponsor
Lahey Clinic
Other
Eligibility
30 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Sep 12, 2026, 7:37 AM EDT
Recruiting Phase 2 Interventional

Intralesional Gardasil-9 for the Treatment of Recalcitrant Warts

NCT07806617
View directory record Official record
Conditions
Warts, Verruca (Warts), Verruca Vulgaris
Interventions
9-valent human papillomavirus vaccine, Sterile Saline
Biological · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 7, 2026 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Kinetic Anesthesia Device Study

NCT03344510
View directory record Official record
Conditions
Local Anaesthetic Complication, Pain
Interventions
Kinetic Anesthesia Device, Control
Device · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 1, 2019 · Synced Sep 12, 2026, 7:37 AM EDT
Recruiting Not applicable Interventional

Office-Based Ureteroscopy Utilizing a Single Use Digital, Flexible Ureteroscope for Upper Tract Urothelial Carcinoma

NCT07630155
View directory record Official record
Conditions
Renal Pelvis and Ureter Urothelial Carcinoma
Interventions
Analgesic Agent, Electronic Health Record Review, Lidocaine Topical, Medical Device Usage and Evaluation, Survey Administration, Ureteroscopy
Drug · Other · Device + 1 more
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Phase 4 Interventional

Low-Dose Lidocaine Infusion for Acute Pain Management Pilot Study

NCT06725485
View directory record Official record
Conditions
Postoperative Pain Management
Interventions
Low-Dose Lidocaine
Drug
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 12, 2026, 7:37 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Quadriceps Motor Unit Adaptation to Simulated Knee Injury

NCT06999057
View directory record Official record
Conditions
Muscle Inhibition, Knee Injury Simulation
Interventions
Joint Effusion via 60 mL Sterile Saline, Intra-articular Lidocaine, Sham injection
Device · Drug · Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 30 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Cervical Transforaminal Epidural Steroid Injection

NCT04544683
View directory record Official record
Conditions
Cervical Radiculopathy, Cervical Spondylosis, Disk, Herniated
Interventions
Cervical Transforaminal Epidural Injection with dexamethasone sodium phosphate
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 9, 2024 · Synced Sep 12, 2026, 7:37 AM EDT
Not listed Phase 2Phase 3 Interventional Accepts healthy volunteers

Treatment of Keratoconus Using Collagen Cross-Linking

NCT00841386
View directory record Official record
Conditions
Keratoconus
Interventions
Riboflavin-5-phosphate, Sham cross-linking
Drug
Lead sponsor
University at Buffalo
Other
Eligibility
16 Years to 35 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
2
States / cities
Amherst, New York • Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 10, 2009 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Comparison of Compounded Topical Anesthetics

NCT06569537
View directory record Official record
Conditions
Procedural Pain
Interventions
Lidocaine topical, BLT
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 12, 2026, 7:37 AM EDT
Terminated Phase 4 Interventional Results available

PROUD Study - Preventing Opioid Use Disorders

NCT04766996
View directory record Official record
Conditions
Anesthesia, Opioid Use
Interventions
Guided mindfulness exercises, Self-administered aromatherapy, Baby aspirin, Tylenol/Acetaminophen, Pregabalin, Prednisone, Meloxicam, Prilosec, Tramadol, Voltaren, Zofran, Pepcid, Reglan, Versed, Lidocaine, Propofol, Ancef, Tranexamic Acid (TXA), Decadron, Bupivacaine hydrochloride, Toradol
Behavioral · Other · Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Not applicable Interventional Results available

Pilot Study: A Randomized Trial Of Anesthetic Agents For Intravitreal Injection

NCT00769392
View directory record Official record
Conditions
Macular Degeneration
Interventions
Proparacaine Ophthalmic, Tetracaine Ophthalmic, Lidocaine 4%, Lidocaine 2% Injectable Solution
Drug
Lead sponsor
Lahey Clinic
Other
Eligibility
40 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
3
States / cities
Arlington, Massachusetts • Burlington, Massachusetts • Peabody, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 8, 2020 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Not applicable Interventional

A Comparison of Scar Infiltration, Scar Deactivation, and Standard of Care for the Treatment of Chronic, Post-Surgical Pain After Cesarean Section

NCT03936309
View directory record Official record
Conditions
Scar, Cesarean Section; Dehiscence
Interventions
Scar Deactivation Surface Release Technique protocol, Scar Infiltration with 0.25-1% Lidocaine, Physical therapy
Other
Lead sponsor
Jennifer Loomis
Federal
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Scott Air Force Base, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Combining Placing a Synera Patch With Propofol/Lidocaine Mixture to Decrease Pain With IV Propofol Injection

NCT02240628
View directory record Official record
Conditions
Pain on IV Injection of Propofol.
Interventions
Lidocaine/tetracaine transdermal patch, Saline, Lidocaine
Device · Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
6 Years to 17 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 21, 2016 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Not applicable Interventional Results available

iPad as a Distraction Tool During Facial Laceration Repair

NCT02217436
View directory record Official record
Conditions
Anxiety, Laceration Repair, Children
Interventions
iPad, Standard Care
Device · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
2 Years to 12 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Phase 4 Interventional Results available

Buffered Lidocaine in the Pediatric Dental Patient

NCT04055116
View directory record Official record
Conditions
Pediatric Dentistry
Interventions
Buffered Lidocaine
Drug
Lead sponsor
Geisinger Clinic
Other
Eligibility
4 Years to 17 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Not applicable Interventional Results available

Lidocaine For Neuroprotection During Cardiac Surgery

NCT00938964
View directory record Official record
Conditions
Cognitive Decline
Interventions
Lidocaine, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
50 Years and older
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
2
States / cities
Durham, North Carolina • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Sep 12, 2026, 7:37 AM EDT
Recruiting Phase 4 Interventional

Propofol-Only Versus Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging

NCT07369128
View directory record Official record
Conditions
MRI Sedation, Pediatric Sedation, Propofol Dosage, Emergence Delirium, Anesthesia, Recovery Time, Dexmedetomidine
Interventions
Dexmedetomidine (IV) 0.5 mcg/kg, Propofol (IV) 2-4 mg/kg, Dexmedetomidine (IV) 1 mcg/kg, Propofol (IV) 1-2 mg/kg, Propofol (IV) Infusion 250 mcg/kg/min, Propofol (IV) Infusion 150 mcg/kg/min
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Year to 12 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Not applicable Interventional Results available

TEOSYAL® RHA Ultra Deep and Perlane-L® for the Correction of Nasolabial Folds

NCT02253147
View directory record Official record
Conditions
Nasolabial Folds, Wrinkles
Interventions
TEOSYAL® RHA Ultra Deep
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
4
States / cities
Beverly Hills, California • Bradenton, Florida • Chapel Hill, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2018 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Not applicable Interventional Results available

Lidocaine and Prevention of Chronic Pain

NCT01619852
View directory record Official record
Conditions
Surgery
Interventions
.9 normal saline placebo, Group L (lidocaine)
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 26, 2019 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Phase 4 Interventional Results available

Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine

NCT04369950
View directory record Official record
Conditions
Physiological Effect of Drugs, Morphine, Analgesics, Analgesics, Opioid, Central Nervous System Depressants, Narcotics
Interventions
2% lidocaine with 1:200,000 epinephrine and epidural morphine, 3% 2-chloroprocaine and epidural morphine
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Phase 4 Interventional Results available

Comparison of Two Application Techniques for LET Gel

NCT04203225
View directory record Official record
Conditions
Lacerations, Pain, Procedural, LET
Interventions
LET Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel
Drug
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
7 Years to 17 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Orange, California • Torrance, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2021 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Injection Technique Assessment of Restylane Silk With Lidocaine for Lip Augmentation

NCT02703948
View directory record Official record
Conditions
Lip Augmentation and Correction of Perioral Rhytids
Interventions
Restylane Silk with Lidocaine
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
4
States / cities
Beverly Hills, California • San Diego, California • Miami, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Sep 12, 2026, 7:37 AM EDT
Recruiting Not applicable Interventional

J-Tip Use for Paracentesis in Adults With Ascites

NCT06996379
View directory record Official record
Conditions
Evaluate Patient Comfort Level During Paracentesis by Numbing Skin With a Needle-less Device, Instead of Using a Needle to Numb the Skin
Interventions
Experimental J-Tip Needle-Free Injection System, Control (Standard treatment)
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 12, 2026, 7:37 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Impact of Pain Scores on Intrauterine Lidocaine Versus Normal Saline Infusion at the Time of IUD Placement

NCT01311102
View directory record Official record
Conditions
Pain
Interventions
Lidocaine, Normal Saline
Drug
Lead sponsor
Women's Health Care Clinic, Torrance, California
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2014 · Synced Sep 12, 2026, 7:37 AM EDT