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Showing 1–24 of 965 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Lidocaine Hydrochloride Clear all
Terminated Not applicable Interventional

Studying Warmed Lidocaine for Increased Analgesic Effect During Intravitreal Injections

NCT06962709
View directory record Official record
Conditions
Pain Intensity Assessment, Pain Management
Interventions
Warmed lidocaine
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Phase 4 Interventional Results available

Loss of Resistance, w/wo Stimulation, For Epidural Placement

NCT03087604
View directory record Official record
Conditions
Anesthesia
Interventions
Thoracic epidural block, Electrical Nerve stimulation, Solution For Thoracic epidural block
Procedure · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 16, 2020 · Synced Sep 25, 2026, 2:12 PM EDT
Completed No phase listed Observational Results available

In Vivo Arthroscopic Behavior of the Infrapatellar Plica of the Knee

NCT00643487
View directory record Official record
Conditions
Anterior Knee Pain Syndrome
Interventions
observation of the behavior of the infrapatellar plica
Procedure
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 23, 2018 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain

NCT05010148
View directory record Official record
Conditions
Postoperative Delirium, Postoperative Pain, Spinal Fusion
Interventions
Lidocaine IV, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years and older
Enrollment
219 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Sep 25, 2026, 2:12 PM EDT
Not listed Phase 2 Interventional

Efficacy of CTM for Tennis ELbow

NCT06171555
View directory record Official record
Conditions
Tennis Elbow, Lateral Epicondylitis \(Tennis Elbow\), Lateral Elbow Tendinopathy
Interventions
CTM, Celestone
Device · Drug
Lead sponsor
Indiana Hand to Shoulder Center
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 26, 2024 · Synced Sep 25, 2026, 2:12 PM EDT
Withdrawn Not applicable Interventional

For A More Comfortable Bronchoscopy: Is Spray Catheter The Answer?

NCT02372760
View directory record Official record
Conditions
Airway Complication of Anaesthesia
Interventions
BA by spray catheter (Olympus PW-205V), BA classic anesthesia, Anesthesia
Device · Other · Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

Decision Support for Intraoperative Low Blood Pressure

NCT02726620
View directory record Official record
Conditions
Hypotension
Interventions
Attending real-time decision support, In-room real-time decision support, Attending feedback emails, In-room provider feedback emails, Anesthesia Information Management System (AIMS), Perioperative Data Warehouse (PDW), General anesthesia, Pager system, Central neuraxial anesthesia, Non-cardiac surgery, Propofol, Sevoflurane, Desflurane, Isoflurane, Ephedrine, Phenylephrine, Norepinephrine, Epinephrine, Dobutamine, Dopamine, Isoproterenol, Milrinone, Atropine, Glycopyrrolate, Vasopressin, Terlipressin, Sodium Chloride 0.9%, Ringer's lactate, Hydroxyethyl starch solutions, Fresh Frozen Plasma, Packed Red Blood Cells, Albumin solutions, Plasma-Lyte, Lidocaine, Bupivacaine, Levobupivacaine, Ropivacaine, Mepivacaine, Tetracaine, Prilocaine, Procaine, Chloroprocaine, Benzocaine, Articaine
Procedure · Device · Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years to 100 Years
Enrollment
22,435 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 15, 2019 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Long Term Effectiveness of Trigger Finger Injections With Triamcinolone vs. Dexamethasone

NCT03641508
View directory record Official record
Conditions
Trigger Finger Disorder
Interventions
Triamcinolone, Dexamethasone
Drug
Lead sponsor
Ericka Lawler
Other
Eligibility
18 Years to 100 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Restylane Lyft With Lidocaine for Augmentation of the Chin Region to Improve the Chin Profile

NCT05777759
View directory record Official record
Conditions
Chin Augmentation, Chin Retrusion
Interventions
Restylane Lyft with Lidocaine, Juvederm Voluma XC
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
11
States / cities
Los Angeles, California • Manhattan Beach, California • Westport, Connecticut + 8 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Pain Control for Laser Epilation in Pilonidal Disease

NCT06640946
View directory record Official record
Conditions
Pilonidal Disease
Interventions
Topical lidocaine, Sham cream
Drug
Lead sponsor
David Mooney
Other
Eligibility
16 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 17, 2025 · Synced Sep 25, 2026, 2:12 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

RHA® 3 Versus Restylane-L® for Lip Augmentation

NCT04540913
View directory record Official record
Conditions
Lip Augmentation, Lip
Interventions
RHA 3, Restylane-L
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Feb 2, 2025 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

Perioperative Intravenous Lidocaine or Epidural Anesthesia on Outcomes in Complex Spine Surgery

NCT00840996
View directory record Official record
Conditions
Spine Surgery
Interventions
Lidocaine, placebo
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 22, 2016 · Synced Sep 25, 2026, 2:12 PM EDT
Terminated Early Phase 1 Interventional

PVB vs Ketamine/Lidocaine in Rib Fracture Patients

NCT04413799
View directory record Official record
Conditions
Rib Fractures, Rib Trauma, Rib Fracture Multiple, Pain, Acute
Interventions
lidocaine, ketamine intravenous infusion, paravertebral block with ropivicaine
Combination Product · Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2025 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Phase 4 Interventional Results available

Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial)

NCT01238536
View directory record Official record
Conditions
Spinal Stenosis, Low Back Pain
Interventions
Epidural steroid with local anesthetic injection, Epidural local anesthetic injection, Epidural steroid injection, Epidural local anesthetic injection
Procedure · Drug
Lead sponsor
University of Washington
Other
Eligibility
50 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
10
States / cities
Redwood City, California • Roseville, California • Denver, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Phase 2 Interventional Results available

Lidocaine as an Endotracheal Tube (ETT) Cuff Media

NCT03343080
View directory record Official record
Conditions
Cardiac Disease
Interventions
1.8% lidocaine plus 0.76% sodium bicarbonate, Air
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Sep 25, 2026, 2:12 PM EDT
Withdrawn Not applicable Interventional

Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes

NCT03543033
View directory record Official record
Conditions
Lumbar Radiculopathy
Interventions
Corticosteroid injection
Drug
Lead sponsor
Lahey Clinic
Other
Eligibility
30 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Sep 25, 2026, 2:12 PM EDT
Recruiting Not applicable Interventional

A Prospective Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain

NCT07214844
View directory record Official record
Conditions
Low Back Pain, Chronic
Interventions
Iovera Medial Branch Cryoneurolysis, Radiofrequency ablation (RFA)
Device · Procedure
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 25, 2026, 2:12 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

A Study Evaluating Blended Belotero for the Treatment of Etched-in Fine Facial Lines

NCT02626598
View directory record Official record
Conditions
Rhytidosis Facialis
Interventions
Blended Belotero
Device
Lead sponsor
Skin Care and Laser Physicians of Beverly Hills
Other
Eligibility
25 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 9, 2015 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Trigger Finger Corticosteroid Injection With and Without Local Anesthetic

NCT04023695
View directory record Official record
Conditions
Trigger Finger
Interventions
Corticosteroid with lidocaine with epinephrine, Corticosteroid with normal saline
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effectiveness Study of Different Local Anesthetic Mixtures

NCT01243112
View directory record Official record
Conditions
Pain
Interventions
1% Lidocaine with Epinephrine (1:100,000), 0.25% Bupivacaine with Epinephrine (1:200,000), 0.5% Lidocaine, 0.125 Bupivacaine, and epi (1:150,000), 1% Lidocaine, 0.5% Bupivacaine, and epinephrine (1:150,000)
Drug
Lead sponsor
Scott and White Hospital & Clinic
Other
Eligibility
18 Years to 60 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Dec 1, 2011 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Topical Radial Artery Vasodilation

NCT01155167
View directory record Official record
Conditions
Cardiac Catheterization, Spasm
Interventions
Nitroglycerin and lidocaine, Placebo
Drug · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Phase 3 Interventional Results available

An Open-label, 8-week Safety, Efficacy, and Assessment of Cooling Methods for Administration of CNTX-4975-05 for Knee OA

NCT03661996
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
CNTX-4975-05, Lidocaine without epinephrine, ElastoGel, Breg Ice Water Pump
Drug · Device
Lead sponsor
Centrexion Therapeutics
Industry
Eligibility
40 Years to 95 Years
Enrollment
854 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
28
States / cities
Birmingham, Alabama • Peoria, Arizona • Tucson, Arizona + 24 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2022 · Synced Sep 25, 2026, 2:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Radiofrequency Microneedling for Facial Rejuvenation

NCT06157853
View directory record Official record
Conditions
Photoaging, Wrinkle
Interventions
Radiofrequency Microneedling, Facial Cleanser, Facial Moisturizer, Sunscreen
Procedure · Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 65 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 9, 2024 · Synced Sep 25, 2026, 2:12 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

TPI Medication Comparison - Ketorolac, Lidocaine, or Dexamethasone

NCT03028012
View directory record Official record
Conditions
Myofascial Pain
Interventions
Ketorolac, Lidocaine, Dexamethasone
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Sep 25, 2026, 2:12 PM EDT