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Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Lidocaine Lubricant Clear all
Completed Phase 3 Interventional Accepts healthy volunteers

Lidocaine for Pessary Check Pain Reduction

NCT05493735
View directory record Official record
Conditions
Pelvic Organ Prolapse, Stress Urinary Incontinence
Interventions
Lidocaine Hcl 2% Jelly, Placebo Jelly
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 13, 2023 · Synced Sep 25, 2026, 9:11 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Double Blinded Randomized Trial Between Lidocaine And Plain Gel For Urethral Straight Catheterization And The Q-Tip Test

NCT00883103
View directory record Official record
Conditions
Pain
Interventions
2% Lidocaine jelly, Plain aqueous gel
Drug
Lead sponsor
Baystate Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 12, 2011 · Synced Sep 25, 2026, 9:11 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Self-Administered Lidocaine Gel for Pain Management With IUD Insertion

NCT02738203
View directory record Official record
Conditions
IUD Insertion
Interventions
Vaginal 2% Lidocaine, Surgical Lubricant Jelly
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2019 · Synced Sep 25, 2026, 9:11 AM EDT
Completed Not applicable Interventional

Lidocaine Lubricant in Pediatric Urethral Catheterization

NCT00596375
View directory record Official record
Conditions
Fevers, Pain
Interventions
Lubricant Instillation, Lidocaine Lubricant
Procedure · Drug
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
2 Months to 2 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 16, 2008 · Synced Sep 25, 2026, 9:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cervical Lidocaine for Intrauterine Device Insertion Pain

NCT01411995
View directory record Official record
Conditions
Pain
Interventions
2% lidocaine gel, Water based lubricant
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 8, 2018 · Synced Sep 25, 2026, 9:11 AM EDT
Withdrawn Not applicable Interventional

Sphenopalatine Ganglion Block for Postdural Puncture Headache in the Emergency Department

NCT02517931
View directory record Official record
Conditions
Postdural Puncture Headache
Interventions
Sphenopalatine Ganglion Block, Placebo
Procedure
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Sep 25, 2026, 9:11 AM EDT
Recruiting Early Phase 1 Interventional

ENDOTRACHEAL Tube LIDOCAINE

NCT07709390
View directory record Official record
Conditions
Emergency Coughing
Interventions
5% Lidocaine Ointment, Water-Based Lubricant
Drug · Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 90 Years
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 25, 2026, 9:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Self-administered Intravaginal 2% Lidocaine Gel Prior to Intrauterine Device Insertion in Nulliparous Women

NCT01534520
View directory record Official record
Conditions
Pain
Interventions
Lidocaine, Placebo
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years to 55 Years · Female only
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 21, 2016 · Synced Sep 25, 2026, 9:11 AM EDT
Completed Not applicable Interventional Results available

Lubricant Versus Lidocaine Gel for Pain Control During Urodynamics

NCT01612156
View directory record Official record
Conditions
Pelvic Floor Disorders
Interventions
2% lidocaine gel, Water based lubricant
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 18, 2015 · Synced Sep 25, 2026, 9:11 AM EDT
Not listed Phase 2Phase 3 Interventional Accepts healthy volunteers

Treatment of Keratoconus Using Collagen Cross-Linking

NCT00841386
View directory record Official record
Conditions
Keratoconus
Interventions
Riboflavin-5-phosphate, Sham cross-linking
Drug
Lead sponsor
University at Buffalo
Other
Eligibility
16 Years to 35 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
2
States / cities
Amherst, New York • Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 10, 2009 · Synced Sep 25, 2026, 9:11 AM EDT
Completed Phase 4 Interventional Results available

Lessons on Urethral Lidocaine in Urodynamics

NCT04038099
View directory record Official record
Conditions
Urethra Issue, Pelvic Organ Prolapse, Urinary Incontinence, Vaginal Vault Prolapse, Cystocele, Uterine Prolapse, Vaginal Prolapse, Pelvic Floor Disorders
Interventions
Water-Based Vaginal Lubricant, lidocaine topical
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Sep 25, 2026, 9:11 AM EDT
Completed Phase 4 Interventional Results available

Intraductal Meibomian Gland Probing Trial

NCT02256969
View directory record Official record
Conditions
Meibomian Gland Dysfunction
Interventions
Blephamide, GenTeal PM Night-Time, Meibomian Gland Probing, Sham Meibomian Gland Probing
Drug · Procedure
Lead sponsor
Joseph B. Ciolino, MD
Other
Eligibility
18 Years to 89 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 18, 2017 · Synced Sep 25, 2026, 9:11 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Topical Lidocaine on the Cervix and Intra-Cervical Prior to Insertion of Intrauterine Devices

NCT01192490
View directory record Official record
Conditions
Contraception
Interventions
Lidocaine, Lubricant
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
Female only
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 15, 2011 · Synced Sep 25, 2026, 9:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Contribution of Urethral Sensory Feedback in Voiding Efficiency

NCT03637582
View directory record Official record
Conditions
Urethral Anesthesia
Interventions
lidocaine gel, Plain aqueous gel
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Sep 25, 2026, 9:11 AM EDT
Completed Phase 4 Interventional

Lidocaine for Pain After Urodynamic Testing

NCT03390790
View directory record Official record
Conditions
Voiding Disorders, Overactive Bladder, Urinary Incontinence
Interventions
Lidocaine gel 2%, Standard lubricant gel
Drug · Other
Lead sponsor
Atlantic Health System
Other
Eligibility
40 Years to 80 Years · Female only
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Sep 25, 2026, 9:11 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Does Lidocaine Gel Decrease Pain Perception in Women Undergoing Diagnostic Flexible Cystoscopy

NCT03347721
View directory record Official record
Conditions
Cystoscopy, Lidocaine, Pain Perception
Interventions
lidocaine gel, Lubricant Gel
Drug
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
129 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 20, 2018 · Synced Sep 25, 2026, 9:11 AM EDT