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ClinicalTrials.gov public records Last synced Sep 28, 2026, 11:42 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Lifestyle/Risk Factor Modification Clear all
Recruiting Not applicable Interventional

Corazones Unidos Study

NCT07298213
View directory record Official record
Conditions
CVD - Cardiovascular Disease, MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Interventions
Your Heart, Your Health
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 28, 2026, 11:42 AM EDT
Recruiting Not applicable Interventional

Preventative Screening and Health Coaching in a Food Insecure Population

NCT06907524
View directory record Official record
Conditions
Cardiovascular Disease Prevention, Cardiometabolic Diseases, Cardiovascular Risk Factor, Cardiovascular Risk Score, Hypertension, Hyperlipidemia, Diabetes, Lifestyle Modification, Health Coaching
Interventions
Longitudinal, Individualized Health Coaching
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
40 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Life's Essential 8 in Midlife Black Women

NCT06707636
View directory record Official record
Conditions
Stress, Self-Efficacy, Heart Disease Risk Factors, Depression Symptoms, Awareness, Perceived Stress, Lifestyle Intervention, Behavior Change
Interventions
Experimental: Black Women's Stress and Wellness (B-SWELL) arm, Active Comparator: Wellness (WE) arm
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
45 Years to 64 Years · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 28, 2026, 11:42 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Covid-19 Long Haul Preventative and Health Promotion Care Clinical Trial Acceleration Program.

NCT06441955
View directory record Official record
Conditions
COVID-19, Long Haul
Interventions
Ritonavir-Boosted Nirmatrelvir (Paxlovid), Physiological Evaluation, Moderna COVID-19 Vaccine, Biopsychological, Behavioral (e.g., Psychotherapy, Lifestyle Counseling), Genetic (including gene transfer, stem cell and recombinant DNA), Multidisciplinary approach
Drug · Diagnostic Test · Biological + 3 more
Lead sponsor
Well- Konnect Healthcare Services and Research Firm
Network
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional Results available

Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)

NCT03423238
View directory record Official record
Conditions
Obesity, Weight Loss, CHD - Coronary Heart Disease
Interventions
Exercise, Health Education, Exercise Compliance, Calorie-Restricted Diet, Behavioral Modification, Weight-Loss Compliance, Dietary Counseling
Other · Behavioral · Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing CVD Risk in African Americans Faith Communities

NCT02235896
View directory record Official record
Conditions
Cardiovascular Disease Risk Factors
Interventions
Education/Behavior Modification
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 30, 2015 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional Results available

Sleep Apnea Intervention for Cardiovascular Disease Reduction

NCT01261390
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Conservative Medical Therapy (CMT), Sham PAP (Sham), Active PAP with RT Support (Active-Beh), Active PAP with Behavioral Modification (Active+Beh)
Behavioral · Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
45 Years to 75 Years
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Sep 28, 2026, 11:42 AM EDT
Active, not recruiting Phase 4 Interventional

Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF)

NCT03603912
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Metformin, Lifestyle/Risk Factor Modification
Drug · Behavioral
Lead sponsor
Mina Chung, MD
Other
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional Results available

Reducing Cardiovascular Risk in Adults With Serious Mental Illness

NCT02451670
View directory record Official record
Conditions
Chronic Disease, Mental Disorder, Health Behavior, Bipolar Disorder, Schizophrenia
Interventions
Prioritized Clinical Decision Support
Behavioral
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
10,347 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
3
States / cities
Duluth, Minnesota • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional

Improving Heart Health in Appalachia

NCT01884246
View directory record Official record
Conditions
Obesity, Hypertension, Hyperlipidemia, Depression
Interventions
Self-care CVD risk reduction, Referral to primary care provider for CVD risk management
Behavioral · Other
Lead sponsor
Debra Moser
Other
Eligibility
21 Years and older
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 9, 2017 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional

Lifestyle Intervention for Treatment of Diabetes

NCT01806727
View directory record Official record
Conditions
Type 2 Diabetes, Overweight, Obesity
Interventions
Community Lifestyle Weight Loss (LWL), Diabetes Self Management (DSM)
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
21 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional

Assessing the Effectiveness of a Weight Watchers-based Lifestyle Intervention for the Primary Prevention of Type 2 Diabetes

NCT02000024
View directory record Official record
Conditions
Prediabetes, Gestational Diabetes Mellitus, Obesity
Interventions
Weight Watchers, National Diabetes Education Program
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 7, 2016 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Heart of the Family: A Cardiovascular Disease and Type 2 Diabetes Risk Reduction Intervention in High-Risk Rural Families

NCT04891575
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Cardiovascular Diseases
Interventions
Active Control Intervention educational sessions, Family Dyad Intervention
Behavioral
Lead sponsor
Gia Mudd
Other
Eligibility
18 Years and older
Enrollment
504 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Sep 28, 2026, 11:42 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Peru Longitudinal Study

NCT03742219
View directory record Official record
Conditions
Cardiovascular Diseases, Diabetes Mellitus, Hypertension, Dyslipidemias, Overweight and Obesity
Interventions
Lifestyle Modification
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
12 Years and older
Enrollment
861 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 14, 2021 · Synced Sep 28, 2026, 11:42 AM EDT
Not listed Not applicable Interventional

A Prospective Evaluation of Health Services Outcomes and Emerging Cardiovascular Disease Biomarkers

NCT00820313
View directory record Official record
Conditions
Coronary Heart Disease, Biomarkers of Cardiovascular Disease
Interventions
Dr. Dean Ornish Program for Reversing Heart Disease
Behavioral
Lead sponsor
Preventive Medicine Research Institute
Other
Eligibility
21 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Sausalito, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2009 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional

The Lifestyle Education About Prediabetes (Leap) Study

NCT05235425
View directory record Official record
Conditions
PreDiabetes
Interventions
Standard NDPP, Very low-carbohydrate diet
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 75 Years
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional Results available

Coordinating Pragmatic Primary Care Population Management for Obesity

NCT03998046
View directory record Official record
Conditions
Obesity, Cardiovascular Risk Factor
Interventions
Outreach Support for Weight Loss Goal Setting and Self-Weighing, Outreach Decision Support to Encourage Linkages to Intensive Community Lifestyle Interventions, Adaptive Tailoring of Information Delivery and Intensity of Primary Care Outreach Support
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 21, 2022 · Synced Sep 28, 2026, 11:42 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Arlington Longitudinal Optimal Healthy Aging Study (ALOHA)

NCT07180147
View directory record Official record
Conditions
Alzheimer Disease (AD), Cardio Vascular Disease, Mild Cognitive Impairment (MCI), Frailty Syndrome, Disability Physical, Hypertension, Metabolic Syndrome (MetS), Healthy Aging, Obesity &Amp; Overweight
Interventions
Not listed
Lead sponsor
Marymount University
Other
Eligibility
50 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional

Healthy Lifestyles After Cancer for Adolescents and Young Adults: A Program to Reduce Cardiovascular Risk Factors

NCT05869604
View directory record Official record
Conditions
Cancer, Cardiovascular Diseases, Weight Management, Pain, Fatigue, Distress, Emotional, Physical Inactivity
Interventions
HEALTHY AYA, Education Control
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 39 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional

Chest Pain Observation Unit Risk Reduction Trial

NCT00536224
View directory record Official record
Conditions
Chest Pain
Interventions
Full counseling, Minimal counseling
Behavioral
Lead sponsor
David A Katz
Other
Eligibility
30 Years to 100 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Sep 28, 2026, 11:42 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Assessing Obesity Related Risk Factors in Adult Population: A Genetic and Behavioral Study

NCT07341841
View directory record Official record
Conditions
Obesity Prevention
Interventions
Diet and exercise, Lifestyle Intervention, Exercise
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 28, 2026, 11:42 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Reducing Diabetes Risk Factors in American Indian Children: Tribal Turning Point

NCT03573856
View directory record Official record
Conditions
Overweight/Obesity
Interventions
Active Living, Health and Safety
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
7 Years to 10 Years
Enrollment
188 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 20, 2022 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Phase 2 Interventional

Heart Disease on the Mend

NCT00127751
View directory record Official record
Conditions
Coronary Heart Disease, Stroke, Hyperlipidemia, Hypertension
Interventions
Enhance health lifestyle changes and medication compliance
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
35 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2003
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 24, 2005 · Synced Sep 28, 2026, 11:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study Investigating the Effectiveness of a LifeSeasons NeuroQ Supplement With Lifestyle Changes to Improve Cognitive Function in Healthy Adults Who Have One or More Risk Factors for Cognitive Decline

NCT04149639
View directory record Official record
Conditions
Healthy
Interventions
NeuroQ
Dietary Supplement
Lead sponsor
LifeSeasons Inc.
Industry
Eligibility
45 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Studio City, California • Flower Mound, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Sep 28, 2026, 11:42 AM EDT