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Showing 1–24 of 500 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Lifestyle modification program Clear all
Active, not recruiting Not applicable Interventional

Food as Medicine for HIV and Diabetes

NCT05026723
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, HIV Infections, PreDiabetes
Interventions
MTM + ILI, Standard MTM
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Think Health! A Personal Weight Management Program

NCT00959608
View directory record Official record
Conditions
Obesity
Interventions
Think Health! program, Basic Plus program
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 70 Years
Enrollment
261 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
5
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 16, 2016 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional

Peau o le Vasa: Analysis of the Efficacy and Feasibility of the PILI Lifestyle Program (PLP) + Social Determinants of Health (SDOH) Intervention and Adaptation of SDOH Measures Pilot Study

NCT06471595
View directory record Official record
Conditions
Weight Loss Trial, Cardiometabolic Syndrome, Hypertension, Dyslipidemia, Pre-diabetes, Type 2 Diabetes Mellitus
Interventions
Partnership for Improving Lifestyle Intervention (PILI) Lifestyle Program + Social Determinants of Health (SDOH) Component
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Fayetteville, Arkansas • Springdale, Arkansas • Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Foundations of Fitness Program Pilot

NCT03622086
View directory record Official record
Conditions
Pediatric Obesity, Health Behavior, Body Mass Index, Self Esteem
Interventions
Foundations of Fitness Program
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
7 Years to 13 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional

Lifestyle, Exercise and Nutrition Study 2 (LEAN 2)

NCT02110641
View directory record Official record
Conditions
Breast Cancer, Weight Loss
Interventions
Weight Loss Counseling
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 20, 2023 · Synced Sep 1, 2026, 4:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Adapting and Assessing the Feasibility of a Telehealth Diabetes Prevention Program for Hispanic Adolescents

NCT06943001
View directory record Official record
Conditions
Obesity and Type 2 Diabetes
Interventions
Fit24+
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
14 Years to 16 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional

A Culturally Tailored Lifestyle Intervention to Prevent Diabetes in South Asians

NCT01084928
View directory record Official record
Conditions
Diabetes, Obesity
Interventions
Lifestyle Intervention Classes
Behavioral
Lead sponsor
Emory University
Other
Eligibility
25 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 24, 2013 · Synced Sep 1, 2026, 4:51 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Study of a Diabetes Prevention Patient Activation Clinical Decision Support Tool

NCT06358261
View directory record Official record
Conditions
PreDiabetes, Lifestyle, Healthy, Activation, Patient
Interventions
Diabetes Prevention Patient Activation Clinical Decision Support Tool
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Lutherville, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 1, 2026, 4:51 PM EDT
Terminated Not applicable Interventional

Early Intervention for Morbidly Obese Patients After Roux-en-Y Gastric Bypass (RYGB) Surgery

NCT01329692
View directory record Official record
Conditions
Weight Loss, Obesity
Interventions
Lifestyle counseling
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 7, 2012 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lifestyle Intervention Program in Overweight Medical Students

NCT03636581
View directory record Official record
Conditions
Overweight
Interventions
Lifestyle counseling
Behavioral
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 35 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jan 17, 2022 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional

Feasibility of Telephone Counseling to Increase Physical Fitness in SCI

NCT02225028
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Physical Activity Counseling
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Financial Incentives to Promote Stimulant Abstinence in a Community-Based Syringe Exchange Program

NCT05787847
View directory record Official record
Conditions
Stimulant Use
Interventions
Incentives for Abstinence, Health Education
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 1, 2026, 4:51 PM EDT
Recruiting Not applicable Interventional

Multi-center Trial to Improve Nocturia and Sleep in Older Adults

NCT06110091
View directory record Official record
Conditions
Nocturia, Insomnia
Interventions
Integrated Behavioral Therapy Program, Health Education Program
Behavioral
Lead sponsor
Atlanta VA Medical Center
Federal
Eligibility
60 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
Los Angeles, California • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 1, 2026, 4:51 PM EDT
Not listed Not applicable Interventional

Digital and Behavioral Tele-Health Tapering Program for Lowering Dependence on Opioids in Patients Undergoing Surgery

NCT04963972
View directory record Official record
Conditions
Malignant Abdominal Neoplasm, Malignant Head and Neck Neoplasm, Malignant Solid Neoplasm, Malignant Thoracic Neoplasm
Interventions
Behavioral Intervention, Best Practice, Questionnaire Administration
Behavioral · Other
Lead sponsor
Lucid Lane, Inc
Industry
Eligibility
18 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional

MyLife: A Digital Health Coaching Program

NCT03529903
View directory record Official record
Conditions
Lifestyle-related Condition, Obesity, Sedentary Lifestyle, PreDiabetes, Hypertension
Interventions
Health Coaching
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 64 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2022 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lifestyle Improvement for Teens With Bariatric Surgery

NCT05393570
View directory record Official record
Conditions
Obesity, Adolescent, Bariatric Surgery Candidate
Interventions
Healthy Lifestyle Behavioral Intervention (MBS -supported intervention)
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
12 Years to 18 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 2, 2025 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional

Pancreatic Nutritional Program for Weight Loss in Overweight/Obese Patients With Stage I-III Breast Cancer

NCT02432950
View directory record Official record
Conditions
Obesity, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage IIA Breast Cancer, Stage IIB Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer
Interventions
Dietary Intervention, Educational Intervention, Laboratory Biomarker Analysis, Quality-of-Life Assessment
Dietary Supplement · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2023 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive and Emotional Skills to Aid Smoking Prevention

NCT03058991
View directory record Official record
Conditions
Tobacco Smoking
Interventions
Distress Tolerance Intervention, Working Memory Intervention, Control Informational Intervention
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
12 Years to 16 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Sep 1, 2026, 4:51 PM EDT
Recruiting Not applicable Interventional

Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center

NCT06897982
View directory record Official record
Conditions
Prediabetic State, PreDiabetes, Health Knowledge, Attitudes, Practice, Nutrition, Healthy, Acceptability of Health Care, Obesity Prevention
Interventions
One-arm feasibility pilot of a nutrition intervention to recruit, engage, and retain DPP participants in the safety-net setting in Los Angeles
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Sep 1, 2026, 4:51 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Shared Decision Making Intervention for Diabetes Prevention in Women With a History of Gestational Diabetes Mellitus

NCT04897945
View directory record Official record
Conditions
Gestational Diabetes Mellitus, Pre-diabetes, Diabetes Mellitus, Type 2
Interventions
Shared decision-making for diabetes prevention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 54 Years · Female only
Enrollment
310 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Los Angeles, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Sep 1, 2026, 4:51 PM EDT
Terminated No phase listed Observational

RESCUE: Discontinuation of GLP-1

NCT07190794
View directory record Official record
Conditions
Obesity
Interventions
OverStitch™ or OverStitch NXT™, Lifestyle Modification
Device · Behavioral
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional

Preventing Diabetes in Latino Youth

NCT02615353
View directory record Official record
Conditions
Obesity, Diabetes
Interventions
Intensive Lifestyle Intervention, Usual Care Control
Behavioral · Other
Lead sponsor
Arizona State University
Other
Eligibility
12 Years to 16 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 13, 2022 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Web-based Physical Activity Intervention to Promote Physical Activity

NCT05803304
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
PATH Intervention, Attention Control Intervention, Physical activity tracker, Dietary education
Behavioral · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 1, 2026, 4:51 PM EDT
Completed Not applicable Interventional Results available

Pragmatic Obstructive Sleep Apnea Weight Loss Trial Assessing Effectiveness and Reach

NCT05104450
View directory record Official record
Conditions
Obesity, Sleep Apnea, Obstructive
Interventions
lifestyle intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
696 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 1, 2026, 4:51 PM EDT