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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Light Exposure Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Impact of Light on Mood

NCT06027944
View directory record Official record
Conditions
Depression
Interventions
Light exposure
Other
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Sep 7, 2026, 11:50 AM EDT
Not yet recruiting Not applicable Interventional

Evaluation of a Novel Indoor Air Pollution Intervention Among Older Adults

NCT07539987
View directory record Official record
Conditions
Cardiovascular Diseases, Blood Pressure, Glycated Hemoglobin (HbA1c), Cholesterol, Cholesterol, HDL, Cholesterol, LDL, Indoor Air Quality, Particulate Matter, Health Behavior
Interventions
Air Improvement and Real-time Monitoring for Wellness through Interactive Strategies and Education (AIRWISE), Portable Air Cleaner (PAC) Control
Behavioral · Other
Lead sponsor
University of Montana
Other
Eligibility
55 Years to 79 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 7, 2026, 11:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

SUV PDL1/PD1 in Sun Damaged & Sun Protected Human Skin of Participants

NCT06177106
View directory record Official record
Conditions
Other Skin Changes Due to Chronic Exposure to Nonionizing Radiation
Interventions
Solar Simulated Light
Other
Lead sponsor
University of Arizona
Other
Eligibility
40 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 7, 2026, 11:50 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Inactivation of Whole Blood With Mirasol

NCT01907906
View directory record Official record
Conditions
Focus of Study: Radiolabel Recovery and Survival of RBCs
Interventions
Mirasol System for Whole Blood
Device
Lead sponsor
Terumo BCTbio
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
2
States / cities
Cincinnati, Ohio • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 17, 2015 · Synced Sep 7, 2026, 11:50 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment

NCT06104280
View directory record Official record
Conditions
Opioid Use Disorder, Sleep Disturbance
Interventions
Post-Illumination Pupillary Response (PIPR), Polysomnography, Multiple Sleep Latency Test, Ecological Momentary Assessments, Actigraphy, DLMO, Melatonin Suppression Test
Other · Behavioral · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 7, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sensor Off Study Using a Nellcor USB Pulse Oximetry Monitor Interface Cable

NCT02265783
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Nellcor USB Pulse Oximeter Monitor Interface Cable
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 30, 2017 · Synced Sep 7, 2026, 11:50 AM EDT
Completed Phase 2 Interventional Results available

Photodynamic Therapy With Porfimer Sodium in Treating Patients With Precancerous Lesions, Cancer, or Other Disease of the Aerodigestive Tract

NCT00453336
View directory record Official record
Conditions
Head and Neck Cancer, Precancerous/Nonmalignant Condition
Interventions
Porfimer Sodium, Photodynamic Therapy
Drug · Procedure
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 120 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 7, 2017 · Synced Sep 7, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating the Effect of SOLIUS UV Light Source in Improving Vitamin D Status

NCT04780776
View directory record Official record
Conditions
Vitamin D Deficiency, Vitamin D Insufficiency
Interventions
UVB treatment, Sham comparator
Device
Lead sponsor
Boston University
Other
Eligibility
22 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced Sep 7, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Brain on Whole Body Hyperthermia: A Neuroimaging Study

NCT02062840
View directory record Official record
Conditions
Major Depression
Interventions
High intensity whole-body infrared heating, Low intensity whole-body infrared heating, Functional Magnetic Resonance Imaging (fMRI) and electrocardiogram (EKG), Questionnaires
Device · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 30 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 9, 2015 · Synced Sep 7, 2026, 11:50 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Violet Device Dosed Ultra Violet-C Light (UV-C) Exposure on Healthy Hand Skin

NCT05313555
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Ultraviolet Light (UV-B), Ultraviolet lights (UV-C) - 1 cycle, Ultraviolet lights (UV-C) - 10 cycles, Ultraviolet lights (UV-C) - 15 cycles, Ultraviolet lights (UV-C) - 25 cycles
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 55 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 7, 2026, 11:50 AM EDT
Recruiting Not applicable Interventional

Feasibility of Light Therapy in the Pediatric Intensive Care Unit (ICU)

NCT07384585
View directory record Official record
Conditions
Circadian Dysregulation, Light Exposure, Pediatric Critical Illness
Interventions
Light Therapy
Other
Lead sponsor
Laura Beth Kalvas
Other
Eligibility
4 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 7, 2026, 11:50 AM EDT
Recruiting No phase listed Observational

Monitoring Pregnancy and Infant Outcomes Following Tralokinumab Exposure During Pregnancy in the US and Canada - PROTECT

NCT05938478
View directory record Official record
Conditions
Atopic Dermatitis, Eczema
Interventions
Tralokinumab
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
Female only
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2035
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Sep 7, 2026, 11:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Gamma Frequency Stimulation in Individuals With Down Syndrome

NCT05196984
View directory record Official record
Conditions
Down Syndrome
Interventions
GENUS device (Active Settings), GENUS device (Sham Settings)
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
25 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 7, 2026, 11:50 AM EDT
Completed Phase 2 Interventional

Hyperbaric Oxygen Effects on Persistent Post-concussive Symptoms

NCT05173818
View directory record Official record
Conditions
Persistent Post-concussive Syndrome, Concussion Post Syndrome
Interventions
Hyperbaric oxygen at 1.5 ATA, Sham treatment
Drug
Lead sponsor
Essentia Health
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 7, 2026, 11:50 AM EDT
Completed Not applicable Interventional

Determining Which Regions of the Brain Are Active During Flight Simulation at Separate Timepoints During Training

NCT06606925
View directory record Official record
Conditions
Cognitive Performance
Interventions
fMRI with virtual reality flight simulator
Diagnostic Test
Lead sponsor
The Geneva Foundation
Other
Eligibility
18 Years to 54 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 7, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Visible Light on the Skin After Administration of Oral Polypodium Leucotomos

NCT02904798
View directory record Official record
Conditions
Photodermatoses
Interventions
Polypodium Leucotomos
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 100 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Sep 7, 2026, 11:50 AM EDT
Not yet recruiting Phase 2 Interventional Accepts healthy volunteers

PDT vs Peels for Treatment of Actinic Keratoses

NCT04429308
View directory record Official record
Conditions
Actinic Keratoses
Interventions
Photodynamic Therapy, Chemical Peels
Procedure · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 7, 2026, 11:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pathophysiology of Circadian Rhythm Delayed Sleep Wake Phase Disorder

NCT06471374
View directory record Official record
Conditions
Delayed Sleep Phase Syndrome, Delayed Sleep Phase
Interventions
Circadian rhythm assessment, Light sensitivity assessment
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
16 Years to 40 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Boulder, Colorado • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 7, 2026, 11:50 AM EDT
Active, not recruiting Not applicable Interventional

The Effect of Light Therapy on Post-Surgical Pain

NCT03674697
View directory record Official record
Conditions
Acute Pain, Arthropathy of Knee
Interventions
Green LED light therapy, White LED light therapy
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Sep 7, 2026, 11:50 AM EDT
Not listed Phase 2Phase 3 Interventional

Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Previously Untreated Corneal Ulcers

NCT05255107
View directory record Official record
Conditions
Keratitis, Corneal Ulcer
Interventions
Standard of Care Therapy + CXL + Riboflavin 0.23% L Solution, Standard of Care Therapy + Sham CXL + Artificial Tears
Combination Product · Other
Lead sponsor
Peschke GmbH
Industry
Eligibility
18 Years and older
Enrollment
468 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Littleton, Colorado • Fort Myers, Florida • Tampa, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2022 · Synced Sep 7, 2026, 11:50 AM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

The Impact of Light Exposure on Cognitive Function in Classrooms

NCT06325150
View directory record Official record
Conditions
Healthy
Interventions
Light emitting glasses
Device
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 7, 2026, 11:50 AM EDT
Completed Not applicable Interventional

Use of Consumer Sleep Technology to Treat Shift Work Disorder

NCT05186233
View directory record Official record
Conditions
Shift-work Disorder
Interventions
Phototherapy
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 7, 2025 · Synced Sep 7, 2026, 11:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SpotCheck: Comparison of Enhanced Telemedicine Versus In-person Evaluation for the Diagnosis of Skin Cancer

NCT04411810
View directory record Official record
Conditions
Skin Cancer
Interventions
Nevisense 3.0, Dermlite Cam, Skin biopsy, Barco Demetra
Device · Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Enrollment
149 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2024 · Synced Sep 7, 2026, 11:50 AM EDT
Completed Not applicable Interventional Results available

30-Minute Light Exposure for the Treatment of Seasonal Affective Disorder

NCT01462305
View directory record Official record
Conditions
Seasonal Affective Disorder
Interventions
goLITE, Control
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 64 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
4
States / cities
Belmont, Massachusetts • Boston, Massachusetts • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2019 · Synced Sep 7, 2026, 11:50 AM EDT