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Showing 1–24 of 64 matching trials from the live ClinicalTrials.gov search.
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Near-infrared Light-emitting Diode (NIR-LED) Therapy for Leber's Hereditary Optic Neuropathy (LHON)

NCT01389817
Conditions
Leber's Hereditary Optic Neuropathy (LHON)
Interventions
Near-infrared light-emitting diode (NIR-LED) therapy (Med Light 630 PRO (Medical Devices Inc.))
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
3
States / cities
Milwaukee, Wisconsin
Completed Phase 1 Interventional Accepts healthy volunteers

High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin

NCT02630303
Conditions
Fibrosis, Scarring, Scar, Wounds, Injuries, Keloid, Cicatrix, Hypertrophic
Interventions
LED-RL Phototherapy, Mock Therapy
Device
Lead sponsor
Jared Jagdeo, MD, MS
Federal
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Mather, California
Conditions
Sleep Disturbance, Insomnia, Acute Coronary Syndrome
Interventions
BLT Intervention, BLB Intervention, Sleep Hygiene Education
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Peripheral Blood Flow Responses to Electromagnetic Energy

NCT02370199
Conditions
Exposure to Man-made Visible Light
Interventions
670 nm light, octafluropropane
Device · Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 59 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of the Use of Low Level Laser Therapy to Reduce Acne

NCT01276535
Conditions
Acne
Interventions
Erchonia MLS + Erchonia THL
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Austin, Texas
Conditions
Diabetic Retinopathy
Interventions
670nm PBM, intravitreous VEGF-inhibitors
Device · Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Meibomian Gland Dysfunction, Dry Eye
Interventions
Red Low-Level Light Therapy
Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Light Emitting Diode Irradiation on the Conduction Parameters of the Superficial Radial Nerve

NCT01513148
Conditions
Peripheral Neuropathy
Interventions
Superluminous light diode
Device
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years to 50 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Winchester, Virginia
Enrolling by invitation Not applicable Interventional

Efficacy of an LED Mask

NCT07890233
Conditions
Fine Lines and Wrinkles, Skin Health, Skin Tone
Interventions
Light emitting diode treatment
Device
Lead sponsor
Therabody, Inc.
Industry
Eligibility
25 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Purchase, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Study of the Use of Orthopulse Photobiomodulation

NCT05650359
Conditions
Orthodontics
Interventions
OrthoPulse, No intervention
Device · Other
Lead sponsor
Biolux Technology GmbH
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Chandler, Arizona
Conditions
Wound Heal
Interventions
Celluma POD
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Irvine, California
Conditions
Quality of Life, Fatigue
Interventions
UVL1000 Treatment Station, Normal Saline Solution, Peripheral Catheterization
Device · Drug
Lead sponsor
UVLrx Therapeutics
Industry
Eligibility
18 Years to 70 Years
Enrollment
3,063 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Safety and Efficacy of REBORN System for Lipolysis Treatment

NCT05507528
Conditions
LIPOLYSIS
Interventions
reborn treatment
Device
Lead sponsor
Lightfective Ltd
Industry
Eligibility
22 Years and older
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tennessee City, Tennessee
Conditions
Seasonal Affective Disorder
Interventions
light exposure from LED source at narrow 468 nm or broader 400-700 nm wavelength
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Gulf War Veterans Illness, Neurobehavioral Manifestations, Memory Disorders
Interventions
Real LED Treatment, Sham LED Treatment
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
38 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
San Francisco, California • Boston, Massachusetts
Conditions
Keratolysis
Interventions
Riboflavin, Dextran, UVA Light Source
Drug · Device
Lead sponsor
Joseph B. Ciolino, MD
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
13
States / cities
Los Angeles, California • Sacramento, California • San Diego, California + 10 more
Conditions
Keratoconus, Ectasia
Interventions
UVA Light with irradiance exposure of 9 mW/cm2, Riboflavin 0.1% ophthalmic solution
Device · Drug
Lead sponsor
Stephen Trokel
Other
Eligibility
16 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2022
U.S. locations
1
States / cities
New York, New York
Conditions
Seasonal Affective Disorder
Interventions
Negative Ion Generator, Light-emitting Photodiode light treatment device
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
3
States / cities
New Haven, Connecticut • Rockville, Maryland • Belmont, Massachusetts
Conditions
Postoperative Facial Ecchymosis, Postoperative Facial Edema
Interventions
ELIXIR MD Photobiomodulation (PBM) System
Device
Lead sponsor
Elixir MD Inc
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Results available

LED Therapy for the Treatment of Concussive Brain Injury

NCT02383472
Conditions
Brain Concussion
Interventions
MedX Health Console model 1100, MedX Health Console model 1100-placebo
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
11 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Waltham, Massachusetts
Conditions
Keratitis, Corneal Ulcer
Interventions
PXL Platinum 330 system + Riboflavin 0.25% TE Solution, Sham CXL + Artificial Tears
Combination Product · Other
Lead sponsor
Peschke GmbH
Industry
Eligibility
18 Years and older
Enrollment
488 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Littleton, Colorado • Fort Myers, Florida • Tampa, Florida + 9 more
Conditions
Depression, Major Depressive Disorder
Interventions
Transcranial Light Therapy, Sham Transcranial Light Therapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Orangeburg, New York
Suspended Early Phase 1 Interventional Accepts healthy volunteers

Feasibility of Polychromatic Light Emitting Diode System to Reduce Pain

NCT03246282
Conditions
Pain
Interventions
UVL1000 Treatment Station, Normal Saline 0.9% Infusion Solution Bag, Peripheral Catheterization
Device · Drug
Lead sponsor
John W. Reeves, MD
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Shreveport, Louisiana
Conditions
Major Depression, Anxiety Disorder, Post-Traumatic Stress Disorder, Substance Abuse Disorder
Interventions
Photobiomodulation with a super-luminous light emitting diode
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts