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ClinicalTrials.gov public records Last synced Sep 6, 2026, 2:05 PM EDT

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Showing 1–24 of 69 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Liner-liner Clear all
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effects of Temperature Control Liner Materials on Long-Term Outcomes of Prothesis Use

NCT03428815
View directory record Official record
Conditions
Artificial Limbs, Skin Diseases
Interventions
Prosthesis suspension liner
Device
Lead sponsor
Goeran Fiedler
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced Sep 6, 2026, 2:05 PM EDT
Completed Not applicable Interventional Results available

Lower Extremity Splinting to Manage Pain and Sleep Disturbances Associated With HIV/AIDS Related Peripheral Neuropathy

NCT01419314
View directory record Official record
Conditions
HIV, AIDS, Peripheral Neuropathy, Pain, Sleep
Interventions
Splinting application to the lower extremities, Splint liner application
Device
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 2, 2013 · Synced Sep 6, 2026, 2:05 PM EDT
Not listed Not applicable Interventional

Long-Term Multi-center Evaluation of E-Poly and Regenerex

NCT00545285
View directory record Official record
Conditions
Osteoarthritis of Hip, Traumatic Arthritis of Hip
Interventions
Total Hip Arthroplasty
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
20 Years to 75 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Sep 6, 2026, 2:05 PM EDT
Terminated Not applicable Interventional

Clinical Study Evaluating Solventum™ Vitrebond™ Pulp Protect Liner/Base for Direct Capping of Pulpal Exposure

NCT07231237
View directory record Official record
Conditions
Dental Caries, Pulp Exposure, Dental, Tooth Decay, Dental Decay
Interventions
Vitrebond™ Pulp Protect Liner/Base
Device
Lead sponsor
Solventum US LLC
Industry
Eligibility
7 Years to 89 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 6, 2026, 2:05 PM EDT
Completed No phase listed Observational

A Clinical Investigation of the C2a-Taper™ Acetabular System

NCT00578851
View directory record Official record
Conditions
Osteoarthritis, Avascular Necrosis, Congenital Hip Dysplasia, Traumatic Arthritis
Interventions
C2a - Taper™ Acetabular System
Device
Lead sponsor
Biomet Orthopedics, LLC
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
2
States / cities
Cedar Rapids, Iowa • Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Sep 6, 2026, 2:05 PM EDT
Withdrawn Not applicable Interventional

Effectiveness of Cotton vs. Waterproof Cast Padding

NCT03859232
View directory record Official record
Conditions
Developmental Dysplasia of the Hip
Interventions
Delta Dry® Waterproof Pantaloon, Cotton Padding
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
0 Years to 5 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Sep 6, 2026, 2:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.

NCT06030297
View directory record Official record
Conditions
Peripheral Neuropathy
Interventions
Diode Laser fiber type Selective Stimulator, ZTlido 1.8 % Topical System, PeriCam PSI NR, Medoc Quantitative Sensory Testing, Inactive Topical System
Procedure · Drug · Diagnostic Test + 1 more
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Palo Alto, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 6, 2026, 2:05 PM EDT
Completed Not applicable Interventional

Study to Determine if Different Prosthetic Sockets Effect How Much Oxygen is in the Tissue of Lower Limb Amputees While They Are Walking

NCT00985842
View directory record Official record
Conditions
Amputation, Diabetes Complications, Leg Injuries, Traumatic Amputation
Interventions
Pe-Lite and sleeve suspension socket, Total Surface bearing a socket with a sleeve suspension but without suction, Total surface bearing suction socket with a pin lock suspension, Total surface bearing suction socket with a sleeve suspension, Vacuum-assisted socket system (Harmony System, Otto Bock)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Sep 6, 2026, 2:05 PM EDT
Completed Phase 3 Interventional

Study of PK and Safety of the LicartTM Topical System in Pediatric and Adult Participants with Minor Soft Tissue Injury

NCT05171673
View directory record Official record
Conditions
Soft Tissue Injuries
Interventions
Licart™ (diclofenac epolamine) topical system
Drug
Lead sponsor
IBSA Institut Biochimique SA
Industry
Eligibility
6 Years to 45 Years
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
11
States / cities
Little Rock, Arkansas • La Palma, California • DeLand, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 6, 2026, 2:05 PM EDT
Recruiting Not applicable Interventional

Polymer Induced Liquid Precursor (PILP) in Adults in With Dentin Caries

NCT06727110
View directory record Official record
Conditions
Dental Caries
Interventions
PILP Cement, PILP Conditioner
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 6, 2026, 2:05 PM EDT
Not listed Not applicable Interventional

Evaluation of the Wear of Vitamin E Treated Polyethylene Components in Primary THA Using RSA

NCT00551967
View directory record Official record
Conditions
Osteoarthritis of Hip, Traumatic Arthritis of Hip
Interventions
Hip replacement
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
20 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Sep 6, 2026, 2:05 PM EDT
Not listed No phase listed Observational

Origin Stem and Logical Cup Post Market Clinical Follow-up

NCT04123600
View directory record Official record
Conditions
Hip Disease
Interventions
Origin Stem and Logical Cup
Device
Lead sponsor
Signature Orthopaedics
Industry
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 21, 2021 · Synced Sep 6, 2026, 2:05 PM EDT
Enrolling by invitation Not applicable Interventional

G7 Freedom Constrained Vivacit-E Liners

NCT05587244
View directory record Official record
Conditions
Osteoarthritis, Hip, Rheumatoid Arthritis, Non-Union Fracture, Trochanteric Fractures, Femoral Neck Fractures, Avascular Necrosis, Dislocation, Hip
Interventions
Total Hip Arthroplasty with G7 Freedom Constrained Vivacit-E Liners
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 80 Years
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2038
U.S. locations
10
States / cities
Birmingham, Alabama • Los Angeles, California • Gainesville, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 6, 2026, 2:05 PM EDT
Enrolling by invitation No phase listed Observational

A Multicenter, Post-Market Clinical Follow-up Study of Subjects With the REDAPT™ System Monolithic Sleeveless/Sleeved Stem and/or Fully Porous Acetabular Shell With XLPE Liner and/or Modular Shell Components Previously Implanted

NCT03610789
View directory record Official record
Conditions
Hip Replacement
Interventions
REDAPT
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2034
U.S. locations
4
States / cities
Rancho Mirage, California • San Diego, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 5, 2025 · Synced Sep 6, 2026, 2:05 PM EDT
Not listed Phase 1 Interventional

YL-13027 in Patients With Advanced Solid Tumors

NCT05228600
View directory record Official record
Conditions
Solid Tumor
Interventions
YL-13027
Drug
Lead sponsor
Shanghai YingLi Pharmaceutical Co. Ltd.
Industry
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Sep 6, 2026, 2:05 PM EDT
Not listed No phase listed Observational

Analysis of Crosslinked and Conventional Polyethylene Explants

NCT01484002
View directory record Official record
Conditions
Osteoarthritis
Interventions
Total hip arthroplasty
Device
Lead sponsor
Anderson Orthopaedic Research Institute
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts • Alexandria, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Sep 6, 2026, 2:05 PM EDT
Terminated No phase listed Observational Results available

Using Intraoperative Sensing Technology to Evaluate Revision Total Knee Arthroplasty

NCT03023410
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
VERASENSE
Procedure
Lead sponsor
Orthosensor, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Sep 6, 2026, 2:05 PM EDT
Completed Not applicable Interventional Results available

Adherence and Perspiration While Wearing Lower Limb Prostheses

NCT03900845
View directory record Official record
Conditions
Lower Extremity Amputation
Interventions
Dynamic Air Exchange - Rising Edge Design (DAE-RED), Perforated elastomeric liner, As-prescribed prosthesis
Device
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 6, 2026, 2:05 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Test Uniformity of Transdermal Drug Delivery to Breast Using Diclofenac Epolamine

NCT01380353
View directory record Official record
Conditions
Breast Cancer
Interventions
Diclofenac epolamine patch
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Sep 6, 2026, 2:05 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Transtibial Pin Lock Suspension at Varying Distraction Values Using a Modified Air Bladder Casting System

NCT04248907
View directory record Official record
Conditions
Amputation
Interventions
0 pound tension, 2 pound tension, 4 pound tension
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Sep 6, 2026, 2:05 PM EDT
Withdrawn Not applicable Interventional

Phototherapy For Treatment Of Raynaud's Phenomenon

NCT04898036
View directory record Official record
Conditions
Raynaud Disease, Raynaud Phenomenon, Raynaud Syndrome
Interventions
Blue Light Therapy, Sham Light Therapy
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 5, 2023 · Synced Sep 6, 2026, 2:05 PM EDT
Recruiting No phase listed Observational

Spartan Stem, World Cup and World Liner Post Market Clinical Follow-up Study

NCT06172569
View directory record Official record
Conditions
Hip Replacement
Interventions
Spartan Stem, World Acetabular Cup and World Liner
Device
Lead sponsor
Signature Orthopaedics
Industry
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 14, 2023 · Synced Sep 6, 2026, 2:05 PM EDT
Completed No phase listed Observational Results available

A Five-Year Metal-on-Metal Retrospective Clinical Study

NCT01481896
View directory record Official record
Conditions
Osteoarthritis
Interventions
Metal-on-metal primary total hip arthroplasty (DePuy )
Device
Lead sponsor
Anderson Orthopaedic Research Institute
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Alexandria, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 8, 2013 · Synced Sep 6, 2026, 2:05 PM EDT
Recruiting Not applicable Interventional

RESET System Pivotal Trial (Rev F)

NCT04101669
View directory record Official record
Conditions
Diabetes type2, Obesity
Interventions
RESET Liner, Sham
Device · Other
Lead sponsor
Morphic Medical Inc.
Industry
Eligibility
22 Years to 65 Years
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Miami, Florida • Boston, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Sep 6, 2026, 2:05 PM EDT