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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:07 AM EDT

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Showing 433–456 of 1,502 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Local ablative therapy Clear all
Recruiting No phase listed Observational

Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers

NCT07140757
View directory record Official record
Conditions
Low Risk, Papillary Thyroid Cancer, Radiofrequency Ablation
Interventions
Questionnaire
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 20, 2026, 5:07 AM EDT
Terminated Phase 3 Interventional Results available

Catheter Ablation Versus Amiodarone for Shock Prophylaxis in Defibrillator Patients With Ventricular Tachycardia

NCT01097330
View directory record Official record
Conditions
Defibrillators, Implantable, Tachycardia, Ventricular
Interventions
Ablation, Amiodarone
Procedure · Drug
Lead sponsor
Population Health Research Institute
Other
Eligibility
19 Years to 84 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
5
States / cities
Chicago, Illinois • Rochester, Minnesota • Philadelphia, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2020 · Synced Oct 20, 2026, 5:07 AM EDT
Completed Not applicable Interventional Results available

Safety Study of MRI-guided Transurethral Ultrasound Ablation of Prostate Tissue to Treat Localized Prostate Cancer

NCT01686958
View directory record Official record
Conditions
Prostate Cancer
Interventions
MR-Guided Transurethral US Ablation of Prostate Tissue
Device
Lead sponsor
Profound Medical Inc.
Other
Eligibility
65 Years to 75 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Oct 20, 2026, 5:07 AM EDT
Completed Phase 3 Interventional Results available

Tailored Treatment of Permanent Atrial Fibrillation

NCT00514735
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Medtronic Cardiac Ablation System, Class I or III Antiarrhythmic Medications
Procedure · Drug
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years to 70 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
23
States / cities
Scottsdale, Arizona • Los Angeles, California • Jacksonville, Florida + 18 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced Oct 20, 2026, 5:07 AM EDT
Completed Phase 4 Interventional Results available

Apixaban Evaluation of Interrupted Or Uninterrupted Anticoagulation for Ablation of Atrial Fibrillation

NCT02608099
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Interrupted apixaban, Uninterrupted apixaban
Drug
Lead sponsor
Baim Institute for Clinical Research
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
19
States / cities
Huntsville, Alabama • Mission Viejo, California • New Haven, Connecticut + 16 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Oct 20, 2026, 5:07 AM EDT
Recruiting Phase 1 Interventional

Intra-tumoral Mitazalimab (CD40 Antibody) With Irreversible Electroporation (IRE) in Locally Advanced Pancreas Cancer

NCT06205849
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
IRE + intratumoral mitazalimab (CD40 antibody) injection, NanoKnife
Drug · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 20, 2026, 5:07 AM EDT
Completed Phase 2 Interventional Results available

Cryotherapy and GM-CSF in Treating Patients With Lung Metastases or Primary Lung Cancer

NCT00514215
View directory record Official record
Conditions
Kidney Cancer, Lung Cancer, Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
sargramostim, flow cytometry, immunoenzyme technique, biopsy, cryosurgery
Biological · Other · Procedure
Lead sponsor
Barbara Ann Karmanos Cancer Institute
Other
Eligibility
18 Years to 120 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Oct 20, 2026, 5:07 AM EDT
Completed Not applicable Interventional

VOLT-AF IDE Clinical Study

NCT06223789
View directory record Official record
Conditions
Atrial Arrhythmia, Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Interventions
Pulsed Field Ablation
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
392 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
26
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 22 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 20, 2026, 5:07 AM EDT
Recruiting No phase listed Observational

Development of Liquid Biopsy Technologies for Noninvasive Cancer Diagnostics in Patients With Suspicious Thyroid Nodules or Thyroid Cancer

NCT04742608
View directory record Official record
Conditions
Thyroid Gland Carcinoma, Thyroid Gland Nodule
Interventions
Biospecimen Collection, Electronic Health Record Review
Procedure · Other
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 20, 2026, 5:07 AM EDT
Completed No phase listed Observational

Safety Monitoring of Patients Having Pulmonary Vein Ablation

NCT00590668
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Transesophageal Echocardiography
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 3, 2017 · Synced Oct 20, 2026, 5:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Surpoint Algorithm for Improved Guidance of Ablation for Ventricular Tachycardia

NCT05618717
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Radiofrequency Ablation
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
19 Years to 80 Years
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Oct 20, 2026, 5:07 AM EDT
Completed Not applicable Interventional

Ultrasound-Based Renal Sympathetic Denervation as Adjunctive Upstream Therapy During Atrial Fibrillation Ablation

NCT04182620
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
renal denervation, Catheter ablation
Device
Lead sponsor
Vivek Reddy
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
13
States / cities
Phoenix, Arizona • Jonesboro, Arkansas • Loma Linda, California + 9 more
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 20, 2026, 5:07 AM EDT
Withdrawn Not applicable Interventional

The Utility of NIOM During LITT for Refractory MTLE

NCT02913742
View directory record Official record
Conditions
Epilepsy, Temporal Lobe
Interventions
monitoring by depth electrode
Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 28, 2017 · Synced Oct 20, 2026, 5:07 AM EDT
Completed Phase 3 Interventional Results available

Hormone Suppression and Radiation Therapy for 6 Months With/Without Docetaxel for High Risk Prostate Cancer

NCT00116142
View directory record Official record
Conditions
Prostate Cancer
Interventions
Docetaxel, Androgen Hormonal Suppression and Radiation, Androgen Suppression Therapy and Radiation Therapy
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
30 Years and older · Male only
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Oct 20, 2026, 5:07 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Study Of Augmented Reality Real-Time Guidance With In-situ Feedback

NCT07822425
View directory record Official record
Conditions
Biopsy, Ablation
Interventions
LUMENA Guidance System
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 20, 2026, 5:07 AM EDT
Completed Not applicable Interventional

Pulmonary Vein (PV) Isolation Versus Box Isolation for the Treatment of Atrial Fibrillation

NCT01091597
View directory record Official record
Conditions
Atrial Fibrillation, Radiofrequency Ablation
Interventions
usual PV ablation, Box isolation of pulmonary veins
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 24, 2010 · Synced Oct 20, 2026, 5:07 AM EDT
Completed Not applicable Interventional Results available

Cryo Balloon for Residual Barrett's Esophagus

NCT02230410
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
CryoBalloon Focal Ablation
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 10, 2022 · Synced Oct 20, 2026, 5:07 AM EDT
Completed Phase 2 Interventional Results available

Hormonal Ablation, Imatinib Mesylate and Docetaxel for Patients With Prostate Cancer

NCT00500110
View directory record Official record
Conditions
Prostate Cancer
Interventions
Docetaxel, Imatinib Mesylate, Leuprolide, Goserelin Acetate
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Male only
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 20, 2026, 5:07 AM EDT
Terminated No phase listed Observational

Physician Assessment of the Clinical Utility of a Patient-Specific 3D Electro-Anatomical Heart Model in VT Ablation

NCT04841382
View directory record Official record
Conditions
Ischemic Monomorphic Ventricular Tachycardia
Interventions
Supporting information.
Other
Lead sponsor
CardioSolv Ablation Technologies
Industry
Eligibility
18 Years to 85 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 19, 2022 · Synced Oct 20, 2026, 5:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Microfidelity (MIFI) Ablation Technology Versus Standard Ablation Catheter for Atrioventricular Nodal Ablation

NCT03114124
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
MIFI Catheter, Standard Ablation Catheter
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Oct 20, 2026, 5:07 AM EDT
Completed Not applicable Interventional Results available

Safety Study of ExAblate for the Treatment of Uterine Fibroids

NCT01142791
View directory record Official record
Conditions
Uterine Fibroids
Interventions
ExAblate
Device
Lead sponsor
InSightec
Industry
Eligibility
18 Years and older · Female only
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
8
States / cities
Los Angeles, California • San Diego, California • San Francisco, California + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Oct 20, 2026, 5:07 AM EDT
Recruiting Phase 4 Interventional

Cryo Rib Fracture Study

NCT06347874
View directory record Official record
Conditions
Rib Fractures
Interventions
Cryoablation, ESP Catheter
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 20, 2026, 5:07 AM EDT
Withdrawn Not applicable Interventional

Evaluation of the XACT Robotic System for Image-guided Percutaneous Lung Procedures

NCT04612985
View directory record Official record
Conditions
CT-guided Minimally Invasive Procedures e.g. Biopsies
Interventions
XACT Robotic System
Device
Lead sponsor
Xact Robotics Ltd.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Oct 20, 2026, 5:07 AM EDT
Terminated Not applicable Interventional Results available

Stepwise Approach To sUbstrate Modification for Ventricular Tachycardia

NCT01546207
View directory record Official record
Conditions
Ventricular Tachycardia, Catheter Ablation, Tachycardia, Ventricular
Interventions
catheter-based ablation
Procedure
Lead sponsor
Vivek Reddy
Other
Eligibility
18 Years to 90 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
6
States / cities
Birmingham, Alabama • Maywood, Illinois • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Oct 20, 2026, 5:07 AM EDT