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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:50 PM EDT

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Showing 625–648 of 1,504 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Local ablative therapy Clear all
Completed Not applicable Interventional Results available

The EMPrint™ Ablate and RESect Study in Patients With Metastatic Lung Tumors (EMPRESS)

NCT02323854
View directory record Official record
Conditions
Lung Cancer
Interventions
Ablation, Surgical Resection
Device · Procedure
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
3
States / cities
Rochester, Minnesota • New York, New York • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Oct 21, 2026, 2:50 PM EDT
Terminated Phase 3 Interventional Results available

AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study

NCT00589303
View directory record Official record
Conditions
Atrial Fibrillation, Heart Failure
Interventions
FDA approved rate and rhythm control drugs, AV Node ablation and device implant
Drug · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
65 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
5
States / cities
Scottsdale, Arizona • Evansville, Indiana • Rochester, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2013 · Synced Oct 21, 2026, 2:50 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the Amigo Robotic System for Ablation of the Cavo-Tricuspid Isthmus

NCT02467179
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Amigo™ Robotic Catheter Manipulation, Manual Catheter Manipulation
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2019 · Synced Oct 21, 2026, 2:50 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

ABLATE WEIGHT (Ablation Plus ESG for Weight Loss)

NCT05578703
View directory record Official record
Conditions
Obesity
Interventions
Fundic Ablation Sequentially in Combination with Endoscopic Sleeve Gastroplasty, Fundic Mucosal Ablation with ERBE HybridAPC, Apollo ESG
Procedure · Device
Lead sponsor
True You Weight Loss
Other
Eligibility
21 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Cary, North Carolina
Source: ClinicalTrials.gov public record
Updated May 14, 2024 · Synced Oct 21, 2026, 2:50 PM EDT
Terminated Phase 4 Interventional Results available

Effect of Dronedarone on Atrial Fibrosis Progression and Atrial Fibrillation Recurrence

NCT04704050
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Fibrillation Recurrent
Interventions
dronedarone 400 mg Oral Tablet, Placebo
Drug
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
Colorado Springs, Colorado • Atlanta, Georgia • New Orleans, Louisiana + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 21, 2026, 2:50 PM EDT
Not listed No phase listed Observational

Impact of the Pulmonary Vein Isolation on Exercise Capacity in Patients With Chronic Atrial Fibrillation

NCT01892774
View directory record Official record
Conditions
Chronic Atrial Fibrillation
Interventions
Radiofrequency catheter ablation
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 10, 2019 · Synced Oct 21, 2026, 2:50 PM EDT
Completed No phase listed Observational

Using Magnetic Resonance Imaging to Evaluate Heart Vessel Function After Angioplasty or Stent Placement Procedures

NCT00692991
View directory record Official record
Conditions
Myocardial Infarction, Angina, Unstable, Cardiomyopathy, Hypertrophic
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Oct 21, 2026, 2:50 PM EDT
Completed No phase listed Observational

Concomitant LAAC/AF Ablation (Watchman FLX Pro)

NCT07041125
View directory record Official record
Conditions
PFA Ablation and LAAC Procedures
Interventions
Watchman FLX™ Pro device.
Device
Lead sponsor
Heart Rhythm Clinical and Research Solutions, LLC
Other
Eligibility
18 Years and older
Enrollment
122 participants
Timeline
2025 – 2026
U.S. locations
15
States / cities
Birmingham, Alabama • San Francisco, California • Littleton, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 21, 2026, 2:50 PM EDT
Completed Phase 1 Interventional

A Study of Pembrolizumab and Cryoablation in People With Mesothelioma

NCT05071014
View directory record Official record
Conditions
Lung Cancer, Unresectable Mesothelioma
Interventions
Pembrolizumab, Image-guided cryoablation
Drug · Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 20, 2023 · Synced Oct 21, 2026, 2:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Uterine Leiomyoma Treatment With Radiofrequency Ablation

NCT01840124
View directory record Official record
Conditions
Uterine Fibroids
Interventions
Radiofrequency ablation of fibroids
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older · Female only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
5
States / cities
Davis, California • Irvine, California • La Jolla, California + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Oct 21, 2026, 2:50 PM EDT
Terminated Not applicable Interventional

The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System

NCT06206746
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Infertility, Female
Interventions
May Health System
Device
Lead sponsor
May Health
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
19
States / cities
Encino, California • San Francisco, California • Tampa, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 21, 2026, 2:50 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry

NCT02346435
View directory record Official record
Conditions
Kidney Neoplasm
Interventions
Not listed
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years to 100 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 21, 2026, 2:50 PM EDT
Withdrawn Not applicable Interventional

Subzero and Scorpion Trial

NCT05032079
View directory record Official record
Conditions
Ductal Carcinoma in Situ
Interventions
cryoablation
Procedure
Lead sponsor
Larkin Community Hospital
Other
Eligibility
18 Years to 95 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Oct 21, 2026, 2:50 PM EDT
Recruiting Phase 2 Interventional

Venous Ethanol for Ventricular Tachycardia

NCT05511246
View directory record Official record
Conditions
Ventricular Tachycardia, Ischemic Cardiomyopathy
Interventions
Venous ethanol, Catheter ablation
Drug · Procedure
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 85 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 21, 2026, 2:50 PM EDT
Completed Not applicable Interventional Results available

iCLAS™ for Persistent Atrial Fibrillation

NCT04061603
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Adagio AF Cryoablation System (iCLAS™)
Device
Lead sponsor
Adagio Medical
Industry
Eligibility
18 Years to 80 Years
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
16
States / cities
Birmingham, Alabama • Phoenix, Arizona • Jonesboro, Arkansas + 13 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 21, 2026, 2:50 PM EDT
Completed Not applicable Interventional Results available

Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue II

NCT03123250
View directory record Official record
Conditions
Benign Prostatic Hyperplasia (BPH)
Interventions
Aquablation
Device
Lead sponsor
PROCEPT BioRobotics
Industry
Eligibility
45 Years to 80 Years · Male only
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
13
States / cities
Phoenix, Arizona • Long Beach, California • Los Angeles, California + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Oct 21, 2026, 2:50 PM EDT
Completed Phase 3 Interventional Results available

The Efficacy and Safety of Degarelix One Month Dosing Regimens in Prostate Cancer

NCT00295750
View directory record Official record
Conditions
Prostate Cancer
Interventions
Degarelix, Leuprolide 7.5 mg
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years and older · Male only
Enrollment
620 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
23
States / cities
Homewood, Alabama • Anchorage, Alaska • Anaheim, California + 18 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2012 · Synced Oct 21, 2026, 2:50 PM EDT
Terminated Phase 4 Interventional Results available

Addition of Excimer Laser to Treatment With Acitretin Tablets for Psoriasis of the Palms and Soles

NCT02181790
View directory record Official record
Conditions
Psoriasis, Skin or Nails
Interventions
Excimer laser, Acitretin
Device · Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 21, 2026, 2:50 PM EDT
Terminated Phase 4 Interventional Results available

Early Ablation Therapy for the Treatment of Ischemic Ventricular Tachycardia in Patients With Implantable Cardioverter Defibrillators

NCT01557842
View directory record Official record
Conditions
Ventricular Tachycardia, Ischemic
Interventions
Drug Treatment, Catheter Ablation
Drug · Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
23
States / cities
Los Angeles, California • San Francisco, California • Aurora, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Oct 21, 2026, 2:50 PM EDT
Completed No phase listed Observational Results available

The Dynamics of Human Atrial Fibrillation

NCT01008722
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Tachyarrhythmia
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 80 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
La Jolla, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 8, 2017 · Synced Oct 21, 2026, 2:50 PM EDT
Completed Not applicable Interventional

Electrohydraulic Versus Laser Lithotripsy for Treatment of Difficult to Remove Biliary Stones

NCT01571271
View directory record Official record
Conditions
Gall Stones
Interventions
Laser Lithotripsy, Electrohydraulic Lithotripsy
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Oct 21, 2026, 2:50 PM EDT
Recruiting No phase listed Observational

Safety and Efficacy of Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA) in the Treatment of Pancreatic Lesions

NCT07737171
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
60 participants
Timeline
2026 – 2033
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 21, 2026, 2:50 PM EDT
Not yet recruiting Not applicable Interventional

High Intensity Focused Ultrasound (HIFU) Ablation for Treatment of Prostate Tissue in Bladder Outlet Obstruction

NCT07194187
View directory record Official record
Conditions
Bladder Outlet Obstruction, BPH
Interventions
High Intensity Focused Ultrasound
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
45 Years to 80 Years · Male only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 21, 2026, 2:50 PM EDT
Terminated Not applicable Interventional Results available

POWER Study (Prospective Transbronchial Microwave + Robotic-Assisted Bronchoscopy)

NCT05299606
View directory record Official record
Conditions
Lung Neoplasms
Interventions
Transbronchial Microwave Ablation
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
22 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
7
States / cities
Stanford, California • Farmington, Connecticut • Minneapolis, Minnesota + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 21, 2026, 2:50 PM EDT