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ClinicalTrials.gov public records Last synced Oct 24, 2026, 4:21 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1081–1104 of 1,504 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Local ablative therapy Clear all
Enrolling by invitation No phase listed Observational

Patient-reported Outcomes Following Percutaneous Ablation of Desmoid Tumors

NCT07755176
View directory record Official record
Conditions
Desmoid Tumor, Aggressive Fibromatoses
Interventions
Desmoid tumor ablation
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 24, 2026, 4:21 AM EDT
Completed Not applicable Interventional Results available

Non-Endoscopic Surveillance for Barrett's Esophagus Following Ablative Therapy

NCT02106910
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
Cytosponge
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 20, 2020 · Synced Oct 24, 2026, 4:21 AM EDT
Not yet recruiting Not applicable Interventional

Estimating The Rate Of Complete Ablation (A0) With The Use Of Biomechanical Deformable Image Registration

NCT07877220
View directory record Official record
Conditions
Liver Tumors
Interventions
RayAblation
Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 24, 2026, 4:21 AM EDT
Completed Not applicable Interventional Results available

Safety & Effectiveness of Duodenal Mucosal Resurfacing (DMR) Using the Revita™ System in Treatment of Type 2 Diabetes

NCT03653091
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Duodenal Mucosal Resurfacing (DMR), Duodenal Mucosal Resurfacing Sham (Sham)
Device
Lead sponsor
Fractyl Health Inc.
Industry
Eligibility
28 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
6
States / cities
Orlando, Florida • Boston, Massachusetts • Lebanon, New Hampshire + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Oct 24, 2026, 4:21 AM EDT
Completed Not applicable Interventional Results available

Evaluation of the Amigo Robotic System for Ablation of the Cavo-Tricuspid Isthmus

NCT02467179
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Amigo™ Robotic Catheter Manipulation, Manual Catheter Manipulation
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2019 · Synced Oct 24, 2026, 4:21 AM EDT
Recruiting Phase 2 Interventional

Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus

NCT06732388
View directory record Official record
Conditions
Barrett Esophagus, Clinical Stage I Esophageal Adenocarcinoma AJCC v8, Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8, Esophageal Adenocarcinoma
Interventions
Biopsy Procedure, Biospecimen Collection, Endoscopic Procedure, Itraconazole, Placebo Administration, Questionnaire Administration, Radiofrequency Ablation
Procedure · Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
6
States / cities
Kansas City, Kansas • Ann Arbor, Michigan • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 24, 2026, 4:21 AM EDT
Recruiting Not applicable Interventional

LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)

NCT04699773
View directory record Official record
Conditions
Glioma, Glioblastoma, Brain Tumor
Interventions
LITT, Hypofractionated Radiation Therapy
Procedure · Radiation
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
5
States / cities
Baltimore, Maryland • Bel Air, Maryland • Columbia, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 24, 2026, 4:21 AM EDT
Enrolling by invitation Not applicable Interventional

Comparing Surgical Management Methods of Atrial Fibrillation

NCT07100483
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Atrial Fibrillation Ablation
Procedure
Lead sponsor
Corewell Health West
Other
Eligibility
18 Years to 85 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 24, 2026, 4:21 AM EDT
Completed Not applicable Interventional

Axumin PETMRI Imaging Following Focal Cryo-ablation (FCA)

NCT04009083
View directory record Official record
Conditions
Prostate Cancer
Interventions
Standard of Care MRI, Fluciclovine PET scan added to MRI
Device · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years · Male only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 30, 2021 · Synced Oct 24, 2026, 4:21 AM EDT
Completed No phase listed Observational

Role of Cardiac Biomarkers in Prediction of Outcome in Atrial Fibrillation Patients Undergoing Catheter Ablation

NCT02208102
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Radio-frequency catheter ablation
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
50 Years to 75 Years
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 19, 2017 · Synced Oct 24, 2026, 4:21 AM EDT
Completed Phase 2 Interventional

Radiofrequency Ablation of Pulmonary Tumors Response Evaluation

NCT00690703
View directory record Official record
Conditions
Non Small Cell Lung Cancer, Pulmonary Metastases
Interventions
RF ablation (Rita Medical Systems Model 1500x)
Device
Lead sponsor
Angiodynamics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2008 · Synced Oct 24, 2026, 4:21 AM EDT
Active, not recruiting Not applicable Interventional

Safety of the Sonablate HIFU System for the Ablation of Incompetent Veins of the Periphery

NCT06642051
View directory record Official record
Conditions
Chronic Venous Insufficiency, CVI, Venous Malformations, Venous Leg Ulcers, Klippel-Trenaunay Syndrome, CLOVES Syndrome, Blue Rubber Bleb Nevus Syndrome
Interventions
High Intensity focused ultrasound
Device
Lead sponsor
Sonablate
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Darien, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Oct 24, 2026, 4:21 AM EDT
Completed Not applicable Interventional Results available

CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF)

NCT01984346
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
AtriCure EPi-Sense-AF Guided Coagulation System with VisiTrax, Endocardial RF Catheter ablation using Open Irrigated-tip RF Abaltion Catheter with unidirectional or bidirectional steering
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
25
States / cities
Birmingham, Alabama • Huntsville, Alabama • Denver, Colorado + 22 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Oct 24, 2026, 4:21 AM EDT
Terminated Not applicable Interventional Results available

Use of the Hansen Medical System in Patients With Paroxysmal Atrial Fibrillation

NCT01122173
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
Ablation
Device
Lead sponsor
Hansen Medical
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
9
States / cities
Mesa, Arizona • Rochester, Minnesota • Englewood, New Jersey + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Oct 24, 2026, 4:21 AM EDT
Terminated No phase listed Observational

DIAMOND AF Post-Approval Study

NCT05230524
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
DiamondTemp™ Ablation System
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Winter Park, Florida
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 24, 2026, 4:21 AM EDT
Withdrawn Not applicable Interventional

Effects of PAP on Afib Recurrence Risk After Catheter Ablation in OSA Patients

NCT03242720
View directory record Official record
Conditions
Obstructive Sleep Apnea, Atrial Fibrillation
Interventions
Cardiac Ablation for Atrial Fibrillation
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Oct 24, 2026, 4:21 AM EDT
Completed No phase listed Observational

WATS3D for the Detection of Esophageal Dysplasia

NCT03008980
View directory record Official record
Conditions
Barrett Esophagus, Esophageal Dysplasia, Esophagus Adenocarcinoma
Interventions
Diagnostic Test
Other
Lead sponsor
CDx Diagnostics
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 4, 2021 · Synced Oct 24, 2026, 4:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Combination Versus Laser Treatment Only

NCT03661697
View directory record Official record
Conditions
Photoaging
Interventions
Laser Therapy, Basic Skin Care Regimen, Lytera
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 24, 2026, 4:21 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Docetaxel, Androgen Ablation, and External-Beam Radiation Therapy in Patients With High-Risk Localized Prostate Cancer

NCT00225420
View directory record Official record
Conditions
Prostate Cancer
Interventions
docetaxel, leuprolide acetate, radiation therapy
Drug · Radiation
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 120 Years · Male only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 1, 2017 · Synced Oct 24, 2026, 4:21 AM EDT
Not listed No phase listed Observational

Therapeutic Endoscopic Ultrasound for Gastrointestinal Disorders: A Multicenter Registry Study

NCT05051358
View directory record Official record
Conditions
Therapeutic Endoscopic Ultrasound, Advanced Endoscopy, Therapeutic Endoscopy, Interventional Endoscopy, Interventional Endoscopic Ultrasound, Gastro-Intestinal Disorder, Gastrointestinal Disease, Gastrointestinal Cancer, Gastrointestinal Dysfunction, Gastrointestinal Fistula, Gastrointestinal Infection, Gastrointestinal Injury, Pancreatic Disease, Bile Duct Diseases
Interventions
Therapeutic Endoscopic Ultrasound
Procedure
Lead sponsor
Advanced Endoscopy Research, Robert Wood Johnson Medical School Rutgers University
Other
Eligibility
Not listed
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 26, 2023 · Synced Oct 24, 2026, 4:21 AM EDT
Completed Phase 2 Interventional

Radiofrequency Interstitial Tissue Ablation in Treating Patients With Localized Renal Cell Carcinoma (Kidney Cancer)

NCT00019955
View directory record Official record
Conditions
Kidney Cancer
Interventions
laparoscopic surgery, radiofrequency ablation, thermal ablation therapy
Procedure
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 29, 2015 · Synced Oct 24, 2026, 4:21 AM EDT
Completed Not applicable Interventional Results available

Cryo Balloon for Residual Barrett's Esophagus

NCT02230410
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
CryoBalloon Focal Ablation
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 10, 2022 · Synced Oct 24, 2026, 4:21 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Post-Ablation Pericarditis Reduction Study

NCT04906720
View directory record Official record
Conditions
Atrial Fibrillation, Catheter Ablation, Pericarditis
Interventions
Colchicine
Drug
Lead sponsor
St. Vincent Cardiovascular Research Institute
Other
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Oct 24, 2026, 4:21 AM EDT
Recruiting No phase listed Observational

The Dynamics of Human Atrial Fibrillation

NCT05366361
View directory record Official record
Conditions
Atrial Fibrillation, Arrhythmias, Cardiac
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 24, 2026, 4:21 AM EDT