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ClinicalTrials.gov public records Last synced Nov 1, 2026, 10:29 AM EST

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Showing 433–456 of 597 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Local block Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Regional Anesthesia in Hip Arthroscopy

NCT02674113
View directory record Official record
Conditions
Femoroacetabular Impingement
Interventions
regional anesthesia bupivacaine, regional anesthesia placebo
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 45 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 10, 2017 · Synced Nov 1, 2026, 10:29 AM EST
Recruiting Early Phase 1 Interventional

Evaluating The Efficacy Of Combined Cognitive Processing Therapy and Stellate Ganglion Blocks for PTSD

NCT06570213
View directory record Official record
Conditions
PTSD
Interventions
Cognitive Processing Therapy, Stellate Ganglion Block
Behavioral · Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Nov 1, 2026, 10:29 AM EST
Completed Phase 2Phase 3 Interventional Results available

Comparative Evaluation of Lumbar Plexus and Suprainguinal Fascia Iliaca Compartment Blocks

NCT03746951
View directory record Official record
Conditions
Orthopedic Disorder
Interventions
Ropivacaine Hcl 0.5% Inj Vil 20Ml
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
2 Years to 18 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Nov 1, 2026, 10:29 AM EST
Active, not recruiting Phase 1 Interventional

Pressure Enabled Intrapancreatic Delivery of SD-101 With Checkpoint Blockade for Locally Advanced Pancreatic Adenocarcinoma

NCT05607953
View directory record Official record
Conditions
Locally Advanced Pancreatic Adenocarcinoma
Interventions
SD-101, anti-PD-1
Drug · Biological
Lead sponsor
TriSalus Life Sciences, Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 4, 2025 · Synced Nov 1, 2026, 10:29 AM EST
Not listed Not applicable Interventional Accepts healthy volunteers

PECS Block in Partial Mastectomy for Postoperative Pain Control

NCT04086394
View directory record Official record
Conditions
Breast Cancer, Postoperative Pain, Opioid Use, Local Anesthesia
Interventions
Pectoral Nerve Block, Surgery without Nerve Block
Procedure
Lead sponsor
Main Line Health
Other
Eligibility
18 Years and older · Female only
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 20, 2020 · Synced Nov 1, 2026, 10:29 AM EST
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Peripheral Nerve Blocks in Pediatric Orthopedic Patients

NCT02236130
View directory record Official record
Conditions
Pediatric Extremity Fracture, Pediatric Extremity Soft Tissue Injury
Interventions
Regional block, General Anesthesia, Local Anesthetic Ropivacaine, Opioids Morphine, Oral pain medication Acetaminophen with Hydrocodone
Procedure · Drug
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
6 Years to 17 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 13, 2017 · Synced Nov 1, 2026, 10:29 AM EST
Withdrawn Not applicable Interventional

Use of Recombinant Hyaluronidase Human is Effective for the Use of Local Blocks for Eyelid's Surgery

NCT02059694
View directory record Official record
Conditions
Upper Eyelid Surgery
Interventions
Hyaluronidase, 2 mL of lidocaine 2% with epinephrine 1:100,000 without rHuPH20
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 19, 2014 · Synced Nov 1, 2026, 10:29 AM EST
Terminated Phase 3 Interventional Results available

International Study to Determine if AdreView Heart Function Scan Can be Used to Identify Patients With Mild or Moderate Heart Failure (HF) That Benefit From Implanted Medical Device

NCT02656329
View directory record Official record
Conditions
Heart Failure
Interventions
Iobenguane I -123 Injection, Implantable Cardioverter Defibrillator, Thyroid blocking
Drug · Device
Lead sponsor
GE Healthcare
Industry
Eligibility
18 Years and older
Enrollment
395 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
29
States / cities
Birmingham, Alabama • Bakersfield, California • La Mesa, California + 24 more
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Nov 1, 2026, 10:29 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Outcomes of Buffered vs. Non-Buffered Lidocaine

NCT02620683
View directory record Official record
Conditions
Blood Levels of Buffered vs Non-buffered Lidocaine, Anesthetics, Local
Interventions
Lidocaine
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 30 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 23, 2018 · Synced Nov 1, 2026, 10:29 AM EST
Terminated Phase 4 Interventional Results available

Lusedra (Fospropofol Disodium) for Minimal to Moderate Sedation for Regional Anesthesia Block Prior to Orthopedic Surgery

NCT01195103
View directory record Official record
Conditions
Procedural Sedation, Regional Anesthesia Block, Orthopedic Surgery
Interventions
Fospropofol disodium, Placebo + Midazolam, Fentanyl
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 29, 2012 · Synced Nov 1, 2026, 10:29 AM EST
Completed Phase 4 Interventional Results available

Liposomal Bupivacaine for Post Operative Pain After Knee Replacement Surgery

NCT02274870
View directory record Official record
Conditions
Post-operative Pain
Interventions
Liposome Bupivacaine, Bupivacaine HCl
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 74 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Valley Stream, New York
Source: ClinicalTrials.gov public record
Updated Jun 14, 2018 · Synced Nov 1, 2026, 10:29 AM EST
Completed Phase 4 Interventional Accepts healthy volunteers

Erector Spinae Plane (ESP) Block for Renal Colic

NCT05323175
View directory record Official record
Conditions
Renal Colic
Interventions
Ropivacaine injection, Standard of care medications
Drug · Other
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Nov 1, 2026, 10:29 AM EST
Recruiting Phase 4 Interventional

Pain Control With Ketorolac and Nerve Block After Wrist and Hand Surgery

NCT07773155
View directory record Official record
Conditions
Surgery, Upper Extremity
Interventions
Toradol, Oxycodone
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Nov 1, 2026, 10:29 AM EST
Terminated No phase listed Observational

Blood Ropivacaine Concentrations Following Chest Wall Nerve Block Continuous Infusion

NCT02860091
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Ropivacaine infusion
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 4 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Nov 1, 2026, 10:29 AM EST
Completed Phase 2 Interventional Results available

Transversus Abdominis Plane Blocks for Patients Undergoing Robotic Gynecologic Oncology Surgery

NCT01444924
View directory record Official record
Conditions
Gynecologic Cancer, Post-operative Pain
Interventions
Bupivicaine, Placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 27, 2019 · Synced Nov 1, 2026, 10:29 AM EST
Completed Phase 1 Interventional Results available

Pectointercostal Fascial Plane Block (PIFB) Alone Versus PIFB With Rectus Sheath Block (RSB) in Cardiac Surgery

NCT04908449
View directory record Official record
Conditions
Coronary Artery Disease, Postoperative Pain, Respiratory Failure
Interventions
Rectus sheath block with bupivacaine
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Nov 1, 2026, 10:29 AM EST
Completed Phase 4 Interventional Results available

Lumbar Plexus vs Quadratus Lumborum Block in Post-operative Pain Following Total Hip Replacement

NCT03801265
View directory record Official record
Conditions
Hip Osteoarthritis
Interventions
Lumbar plexus block, Quadratus lumborum type 3 block, Ropivacaine injection
Procedure · Drug
Lead sponsor
Sharad Khetarpal
Other
Eligibility
18 Years to 90 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2021 · Synced Nov 1, 2026, 10:29 AM EST
Completed Phase 4 Interventional Accepts healthy volunteers

A Comparison of UGBRS Block and Local Infiltration

NCT02352519
View directory record Official record
Conditions
Appendicitis
Interventions
UGBRSB, Local Infiltration
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
6 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 21, 2015 · Synced Nov 1, 2026, 10:29 AM EST
Completed Phase 4 Interventional Results available

The Combination of Adductor Canal Block and Periarticular Injection. A Novel Technique for Patients Undergoing Total Knee Replacement (ACB PAI)

NCT02292082
View directory record Official record
Conditions
Osteoarthritis
Interventions
Bupivacaine, Morphine, Methylprednisolone, Cefazolin, Normal saline, Midazolam, Propofol, Dexamethasone, 8 MHz. Chiba needle, 22 G / 4 inches
Drug · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 11, 2019 · Synced Nov 1, 2026, 10:29 AM EST
Active, not recruiting Not applicable Interventional

Stellate Ganglion Block for PTSD

NCT05169190
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Stellate Ganglion Block, Sham Stellate Ganglion Block
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
6
States / cities
Long Beach, California • Tampa, Florida • Minneapolis, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Nov 1, 2026, 10:29 AM EST
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Quadratus Lumborum vs Erector Spinae Supplementary Blocks With Lumbar Plexus Blocks for Hip PAO

NCT04481451
View directory record Official record
Conditions
Pain, Postoperative, Regional Anesthesia, Hip Dysplasia
Interventions
Erector spinae block with ropivacaine 0.2%, Quadratus lumborum block with ropivacaine 0.2%, Ropivacaine
Procedure · Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
15 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Nov 1, 2026, 10:29 AM EST
Completed Not applicable Interventional Results available

QL vs PENG for Analgesia After Hip Arthroplasty

NCT05710107
View directory record Official record
Conditions
Block, Hip Replacement, Postoperative Pain
Interventions
PENG + LFC Block, QL Block
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 20, 2024 · Synced Nov 1, 2026, 10:29 AM EST
Terminated Phase 3 Interventional Results available

A Prospective Controlled Treatment Trial for Post-Traumatic Headaches

NCT03007420
View directory record Official record
Conditions
Post-Traumatic Headaches
Interventions
Occipital Nerve Block (ONB) using lidocaine and dexamethosone, Cervical Medial Branch Block (CMBB) using lidocaine and dexamethosone
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 45 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Nov 1, 2026, 10:29 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Transversus Abdominis Plane Block Versus Local Injection of Pain Medication

NCT02314104
View directory record Official record
Conditions
Pain, Postoperative
Interventions
ropivacaine
Drug
Lead sponsor
Liberman, Eric, D.O.
Individual
Eligibility
18 Years and older · Female only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Livingston, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Nov 1, 2026, 10:29 AM EST