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ClinicalTrials.gov public records Last synced Oct 19, 2026, 4:46 AM EDT

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Showing 1–24 of 66 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Loneliness Intervention Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

LEAPTogether: An Intergenerational Intervention to Address Loneliness and Social Isolation

NCT05831475
View directory record Official record
Conditions
Social Isolation, Loneliness, Intergenerational Relations
Interventions
Intergenerational Virtual Paired Exercise, Peer Virtual Paired Exercise
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Oct 19, 2026, 4:46 AM EDT
Recruiting Not applicable Interventional

Engage Coaching (R33 Phase)

NCT07488559
View directory record Official record
Conditions
Social Connection, Loneliness, Suicide Ideation, Social-emotional Quality of Life
Interventions
Social Engage Coaching (S-ENG)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Smartphone Intervention for Relational and Mental Well Being

NCT04629755
View directory record Official record
Conditions
Depression, Loneliness, Relation, Interpersonal, Covid19
Interventions
Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,765 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Learning to PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia

NCT04649164
View directory record Official record
Conditions
Lewy Body Disease, Parkinson Disease Dementia, Dementia With Lewy Bodies
Interventions
Peer mentor support and caregiver intervention, Focus group to provide feedback on educational materials and mentoring program
Behavioral · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
21 Years to 90 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Phase 2 Interventional

Social Connections and Healthy Aging (The Senior Connection)

NCT01408654
View directory record Official record
Conditions
Suicidal Ideation, Depression
Interventions
Peer Companionship
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2016 · Synced Oct 19, 2026, 4:46 AM EDT
Enrolling by invitation Not applicable Interventional

Adapting and Pilot Testing a Loneliness Intervention for Cancer Survivors

NCT07418437
View directory record Official record
Conditions
Cancer Survivorship, Loneliness
Interventions
Social Prescribing Group, Usual Care
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional

Computerized Intervention for Interpersonal Stress

NCT04271111
View directory record Official record
Conditions
Hostility
Interventions
Online Treatment for Interpersonal Stress, Physical Health Education Tool
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 9, 2021 · Synced Oct 19, 2026, 4:46 AM EDT
Recruiting Not applicable Interventional

Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial

NCT07223736
View directory record Official record
Conditions
Pelvic Floor Disorder, Loneliness, Postpartum, Mental Health, Depression, Peritraumatic Distress, Women, Artificial Intelligence (AI), Chatbot
Interventions
Generative artificial intelligence (genAI) postpartum chatbot, Standard of Care (SOC)
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional

iWellness Study to Evaluate a Mental Health App for Students

NCT05234970
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Wysa, Harvard College App
Other
Lead sponsor
Harvard University
Other
Eligibility
18 Years and older
Enrollment
289 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional Results available

SAFER: A Brief Intervention Involving Family Members in Suicide Safety Planning

NCT03034863
View directory record Official record
Conditions
Suicide
Interventions
Safe Actions for Families to Encourage Recovery, Individual Safety Planning Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 10, 2021 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Music Therapy and Social Work Telehealth for Older Adult Well-Being

NCT06219148
View directory record Official record
Conditions
Aging Well, Dementia, Telemedicine
Interventions
Music Therapy Telehealth, Non-Collaborative Social Work Telehealth, Collaborative Social Work Telehealth
Behavioral
Lead sponsor
Alaine E Hernandez, PhD
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Lexington, Kentucky • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Combatting Social Isolation in Older Adults

NCT05426837
View directory record Official record
Conditions
Loneliness, Social Isolation
Interventions
Combatting Social Isolation, Health Education Training
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
60 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Heartfulness Self-Care Program on Anxiety, Satisfaction With Life, and Loneliness Levels in Students and Staff in High Schools.

NCT05874232
View directory record Official record
Conditions
Anxiety, Satisfaction With Life, Loneliness
Interventions
Self-Care Program through Heartfulness
Behavioral
Lead sponsor
Heartfulness Institute
Other
Eligibility
14 Years to 80 Years
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Decreasing Loneliness to Optimize Pain Care

NCT06285032
View directory record Official record
Conditions
Loneliness, Opioid Use
Interventions
Cognitive Behavior Therapy (CBT), Social Navigation Group, Controlled Group
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ADHOC Mindfulness-Based Research

NCT04580082
View directory record Official record
Conditions
Hiv, Loneliness, Depression, Anxiety
Interventions
Mindfulness lessons
Behavioral
Lead sponsor
Mazonson & Santas Inc.
Industry
Eligibility
50 Years and older
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Larkspur, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Mobile App to Address Student Loneliness

NCT04164654
View directory record Official record
Conditions
Loneliness
Interventions
Loneliness Intervention
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 25 Years
Enrollment
221 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 15, 2022 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Social Activity, Loneliness and Stigma During COVID-19 Outbreak

NCT04734171
View directory record Official record
Conditions
Covid19, Fear, Loneliness
Interventions
Digital social activity video intervention, Informational sheet, Stigma awareness video intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 70 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional

Study 1: Social Engage Coaching R61 Phase

NCT05745493
View directory record Official record
Conditions
Social Isolation, Loneliness, Suicide Ideation, Quality of Life
Interventions
Social Engage Coaching (S-ENG)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Oxytocin and Social Behavior Over the Lifespan

NCT00914953
View directory record Official record
Conditions
Social Activity
Interventions
oxytocin (Pitocin)
Drug
Lead sponsor
Claremont Graduate University
Other
Eligibility
50 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2012 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional

Computerized Intervention for Loneliness

NCT03839966
View directory record Official record
Conditions
Loneliness
Interventions
Interpretation Bias Modification for Loneliness, Healthy Habits Psychoeducation and Relaxation
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Jan 29, 2021 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional

Reduce Loneliness in Care Partners of Persons With AD/ADRD

NCT05460494
View directory record Official record
Conditions
Loneliness
Interventions
RELOAD-C
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Manhasset, New York • New Hyde Park, New York • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Volunteer-based Lunch Program on Feelings of Loneliness in Elders

NCT03552328
View directory record Official record
Conditions
Aged, Loneliness, Depression, Anxiety
Interventions
Lunch with Medical Student, Control
Other
Lead sponsor
University of South Florida
Other
Eligibility
60 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Oct 19, 2026, 4:46 AM EDT
Completed Not applicable Interventional Results available

Mental Health Among Patients, Providers, and Staff During the COVID-19 Era

NCT04700137
View directory record Official record
Conditions
Covid19, Mental Health
Interventions
Caring Contacts Plus Introductory Phone Call (CC+), Caring Contacts without an introductory phone call (CC)
Other
Lead sponsor
St. Luke's Health System, Boise, Idaho
Other
Eligibility
12 Years and older
Enrollment
666 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Jan 25, 2024 · Synced Oct 19, 2026, 4:46 AM EDT
Active, not recruiting Not applicable Interventional

Occupational Therapy Led Social Prescription for People With Parkinson Disease

NCT06447207
View directory record Official record
Conditions
Parkinson Disease
Interventions
Occupational Therapy Led Social Prescription
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 19, 2026, 4:46 AM EDT