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Showing 1–24 of 66 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Loneliness Intervention Clear all
Completed Not applicable Interventional Results available

Open Pilot Trial of a Mind-Body Sexual Well-Being Intervention for Female GI Cancer Survivors

NCT06331403
View directory record Official record
Conditions
Colorectal Cancer, Anal Cancer, Sexual Dysfunction
Interventions
Mind-Body Group Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Quality of Life for Older Adults With and Without Mild Cognitive Impairment (MCI) Through Social Engagement Over Video Technology

NCT05380180
View directory record Official record
Conditions
Aging, Mild Cognitive Impairment, Aging Well
Interventions
OneClick Social Engagement Intervention, OneClick Social Engagement Intervention Extension
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
65 Years and older
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Champaign, Illinois • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 4, 2026, 1:42 AM EDT
Recruiting Not applicable Interventional

A Community Health Worker-Led Program for Chronic Pain and Loneliness in Older Adults

NCT06671925
View directory record Official record
Conditions
Chronic Pain
Interventions
Strengthening COnnections to Overcome Pain (SCOOP)
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional

The Effects of Yoga on Body Image in College Women

NCT03262350
View directory record Official record
Conditions
Body Image, Eating Disorder, Obesity, Yoga
Interventions
Yoga
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 26 Years · Female only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Apr 26, 2021 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional

Social Prescribing and Relationship Cognitive Strategies (SPARCS)

NCT06656975
View directory record Official record
Conditions
Social Isolation, Suicidal Ideation
Interventions
Brief Cognitive Therapy, Social Prescribing, Enhanced Usual Care
Behavioral · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Brighton, Michigan • Canton, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Group-Based Online Virtual Reality Gaming to Improve Mental Health Among Children With Physical Disabilities

NCT05259462
View directory record Official record
Conditions
Disability Physical
Interventions
Intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
13 Years to 19 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Sep 4, 2026, 1:42 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Occupational Therapy for Mental Health and Engagement in Neurorehabilitation

NCT07375485
View directory record Official record
Conditions
Acquired Brain Injury, Mental Health, Depressive Symptoms, Anxiety Symptoms, Loneliness
Interventions
Multifaceted implementation program
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Denver, Colorado • Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 4, 2026, 1:42 AM EDT
Recruiting Not applicable Interventional

Characterizing the Impact of Presbyphonia on Social Interaction

NCT06441136
View directory record Official record
Conditions
Presbyphonia
Interventions
PhoRTE Program, University of California Los Angeles (UCLA) Loneliness Scale, Social Disconnectedness Scale, Patient Health Questionnaire 9, Aging Voice Index, The Edmonton Frail Scale, Vocal Effort Scale, Montreal Cognitive Assessment, Voice Handicap Index-10, Voice Problem Impact Scales, Cough Severity Index, Laryngoscopy, Acoustic, perceptual, and aerodynamic assessments
Other · Procedure
Lead sponsor
Matthew R. Hoffman
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional

Alcohol Cessation Among Head and Neck Cancer Survivors

NCT05570851
View directory record Official record
Conditions
Head and Neck Cancer, Alcohol Use, Unspecified
Interventions
Alcohol Cessation Text Messages, Usual Care
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 4, 2026, 1:42 AM EDT
Not yet recruiting Not applicable Interventional

Comparing the Impact of Peer Support vs. Staff-Delivered Transportation Interventions for Young Adults With Intellectual and Developmental Disabilities.

NCT07505121
View directory record Official record
Conditions
Intellectual Disability, Mild to Moderate, Developmental Disability
Interventions
Ready to Ride - Standard Delivery, Ready to Ride - Peer Support Delivery
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 27 Years
Enrollment
325 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Gainesville, Florida • Minneapolis, Minnesota • Durham, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Proactive Social Robot for Older Adults in Reducing Loneliness and Social Isolation

NCT03972787
View directory record Official record
Conditions
Loneliness, Mood, Quality of Life
Interventions
Proactive social robot
Device
Lead sponsor
Baycrest
Other
Eligibility
70 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2021 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Combatting Social Isolation in Older Adults

NCT05426837
View directory record Official record
Conditions
Loneliness, Social Isolation
Interventions
Combatting Social Isolation, Health Education Training
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
60 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Sep 4, 2026, 1:42 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Using Virtual Reality Travel to Reduce Loneliness in Older Adults

NCT07644416
View directory record Official record
Conditions
Loneliness, Older Adults (65 Years and Older), Virtual Reality, Leisure Activities
Interventions
Virtual Reality Travel, Puzzle-Based Attention Control Activity
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Bloomington, Indiana • Ellettsville, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional

Testing the Effectiveness of an Online Behavioral Intervention in Reducing Loneliness

NCT04112225
View directory record Official record
Conditions
Psychological Distress, Loneliness
Interventions
Happify
Behavioral
Lead sponsor
Happify Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
890 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 1, 2020 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional

Computerized Intervention for Loneliness

NCT03839966
View directory record Official record
Conditions
Loneliness
Interventions
Interpretation Bias Modification for Loneliness, Healthy Habits Psychoeducation and Relaxation
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional

Building Closer Friendships in Social Anxiety Disorder

NCT03671577
View directory record Official record
Conditions
Social Anxiety
Interventions
Building Closer Friendships
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 65 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Learning to PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia

NCT04649164
View directory record Official record
Conditions
Lewy Body Disease, Parkinson Disease Dementia, Dementia With Lewy Bodies
Interventions
Peer mentor support and caregiver intervention, Focus group to provide feedback on educational materials and mentoring program
Behavioral · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
21 Years to 90 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional Results available

Mindfulness to Reduce Loneliness in Older Caregivers

NCT04560088
View directory record Official record
Conditions
Social Isolation, Loneliness
Interventions
Mindfulness, Breathing
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
50 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Sep 4, 2026, 1:42 AM EDT
Not listed Not applicable Interventional

Acceptability/Feasibility of COVID-19 Intervention

NCT05019053
View directory record Official record
Conditions
Social Isolation, Emotional Disorder
Interventions
Coping Crew
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 17, 2022 · Synced Sep 4, 2026, 1:42 AM EDT
Not yet recruiting Phase 2 Interventional

Retreat-Based Program for Violence-Exposed Women Veterans

NCT07738445
View directory record Official record
Conditions
Suicide Prevention
Interventions
GRIT, GRI
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
West Haven, Connecticut • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional

Reduce Loneliness in Care Partners of Persons With AD/ADRD

NCT05460494
View directory record Official record
Conditions
Loneliness
Interventions
RELOAD-C
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Manhasset, New York • New Hyde Park, New York • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional Results available

Suicide Safety Planning Group Treatment: "Project Life Force"

NCT02525575
View directory record Official record
Conditions
Suicide
Interventions
Project Life Force Group Treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 24, 2019 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional Results available

SAFER: A Brief Intervention Involving Family Members in Suicide Safety Planning

NCT03034863
View directory record Official record
Conditions
Suicide
Interventions
Safe Actions for Families to Encourage Recovery, Individual Safety Planning Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 9, 2021 · Synced Sep 4, 2026, 1:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Music Therapy and Social Work Telehealth for Older Adult Well-Being

NCT06219148
View directory record Official record
Conditions
Aging Well, Dementia, Telemedicine
Interventions
Music Therapy Telehealth, Non-Collaborative Social Work Telehealth, Collaborative Social Work Telehealth
Behavioral
Lead sponsor
Alaine E Hernandez, PhD
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Lexington, Kentucky • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Sep 4, 2026, 1:42 AM EDT