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ClinicalTrials.gov public records Last synced Oct 20, 2026, 6:32 AM EDT

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Showing 265–288 of 3,723 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Loss Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Time Restricted Feeding for Weight Loss and Cardio-protection

NCT02948517
View directory record Official record
Conditions
Coronary Disease, Weight Loss
Interventions
Time restricted feeding
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
25 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Not applicable Interventional Results available

ENDObesity® II Study: TransPyloric Shuttle® System for Weight Loss

NCT02518685
View directory record Official record
Conditions
Obesity
Interventions
TransPyloric Shuttle, Sham procedure, Lifestyle Counseling
Device · Behavioral
Lead sponsor
BaroNova, Inc.
Industry
Eligibility
22 Years to 60 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
9
States / cities
Scottsdale, Arizona • San Diego, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Phase 4 Interventional

The Evaluation of the Efficacy and Safety of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment (MCI)

NCT00293176
View directory record Official record
Conditions
Memory Loss
Interventions
Donepezil Hydrochloride, Placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
45 Years to 90 Years
Enrollment
821 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
54
States / cities
Albaster, Alabama • Mesa, Arizona • Peoria, Arizona + 51 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2011 · Synced Oct 20, 2026, 6:32 AM EDT
Completed No phase listed Observational

Body Composition & REE Responses to Bariatric Surgery

NCT00682058
View directory record Official record
Conditions
Weight Loss, Weight Change
Interventions
Follow-up post-bariatric surgery
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2019 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Phase 3 Interventional

Safety and Efficacy Study of ALZT-OP1 in Subjects With Evidence of Early Alzheimer's Disease

NCT02547818
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
ALZT-OP1a, ALZT-OP1b, Placebo ALZT-OP1a, Placebo ALZT-OP1b
Drug · Other
Lead sponsor
AZTherapies, Inc.
Industry
Eligibility
55 Years to 79 Years
Enrollment
620 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
69
States / cities
Gilbert, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 56 more
Source: ClinicalTrials.gov public record
Updated Nov 10, 2021 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Treatments for Fathers With ADHD and Their At-Risk Children (Fathers Too)

NCT02675400
View directory record Official record
Conditions
Attention Deficit/Hyperactivity Disorder (ADHD)
Interventions
Vyvanse, Behavioral Parent Training, Methylphenidate
Drug · Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
21 Years to 55 Years · Male only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Oct 20, 2026, 6:32 AM EDT
Recruiting Not applicable Interventional

Long-term, Substantial Weight Loss and Insulin Regulation of Lipolysis

NCT03868592
View directory record Official record
Conditions
Obesity, Morbid
Interventions
Gastric sleeve/bariatric surgery
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Not applicable Interventional

New Media Obesity Treatment in Community Health Centers

NCT01827800
View directory record Official record
Conditions
Obesity
Interventions
eHealth weight loss intervention
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 13, 2018 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Self-Efficacy in Weight Loss Treatment

NCT00896194
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Standard Behavioral Treatment, Modified Standard Behavioral Intervention + Self-Efficacy
Behavioral
Lead sponsor
Lora Burke
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2015 · Synced Oct 20, 2026, 6:32 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

"Efficacy in Adolescents of Continued Behavior Modification Following a Six Month Sibutramine-based Weight Management Intervention"

NCT01023139
View directory record Official record
Conditions
Obesity
Interventions
Sibutramine
Behavioral
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
12 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2009 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aging, Lifestyle and Inflammation in Veterans Exercising

NCT00667030
View directory record Official record
Conditions
Inflammation, Aging, Metabolism, Exercise
Interventions
Weight loss and aerobic exercise training
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Effect of Vitamin K on Age-Related Bone Loss and Vascular Calcification

NCT00183001
View directory record Official record
Conditions
Osteoporosis, Vascular Calcification, Inflammation
Interventions
Vitamin K
Drug
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
60 Years to 80 Years
Enrollment
452 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 16, 2009 · Synced Oct 20, 2026, 6:32 AM EDT
Completed No phase listed Observational

Study of Physical and Mental Health of Older Patients With Newly Diagnosed Cancer

NCT00769951
View directory record Official record
Conditions
Cognitive/Functional Effects, Depression, Hematopoietic/Lymphoid Cancer, Malnutrition, Pain, Psychosocial Effects of Cancer and Its Treatment, Unspecified Adult Solid Tumor, Protocol Specific, Weight Changes
Interventions
medical chart review, questionnaire administration, cognitive assessment, psychosocial assessment and care, quality-of-life assessment
Other · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
65 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Not applicable Interventional Results available

ACHIEVE Hearing Intervention Follow-Up Study

NCT05070429
View directory record Official record
Conditions
Hearing Loss, Aging
Interventions
Clinic-based audiological rehabilitative service delivery, Telehealth audiological rehabilitative service delivery
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
73 Years to 88 Years
Enrollment
339 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
4
States / cities
Hagerstown, Maryland • Minneapolis, Minnesota • Jackson, Mississippi + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Not applicable Interventional

Delayed Cord Clamping at Term Cesarean

NCT03150641
View directory record Official record
Conditions
Maternal Blood Loss, Cesarean Delivery, Delayed Cord Clamping, Neonatal Health
Interventions
Umbilical cord clamping
Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Phase 3 Interventional

Comparison of Nutritional Supplements in Preventing Weight Loss in Patients With Cancer

NCT00053053
View directory record Official record
Conditions
Cachexia, Lymphoma, Lymphoproliferative Disorder, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
Juven, Non-Juven Supplement
Dietary Supplement
Lead sponsor
Radiation Therapy Oncology Group
Network
Eligibility
17 Years to 120 Years
Enrollment
472 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
230
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 181 more
Source: ClinicalTrials.gov public record
Updated Dec 8, 2016 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Not applicable Interventional

Teaching Obesity Treatment Options to Adult Learners (TOTAL): A Multisite RCT

NCT05346575
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Teaching Obesity Treatments to Adult Learners (TOTAL), Usual care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
West Los Angeles, California • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Not applicable Interventional Results available

Changing Lifestyles for Better Health

NCT00848757
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Intensive Lifestyle Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

To Predict Weight Loss Response to Liraglutide (Saxenda®), From fMRI-based Determination of Food Cue Reactivity

NCT03795701
View directory record Official record
Conditions
Obesity
Interventions
Saxenda®, Placebo
Drug · Other
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 60 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
2
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Dec 4, 2023 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of IMG-007 in Adult Alopecia Areata Participants

NCT06060977
View directory record Official record
Conditions
Alopecia Areata (AA)
Interventions
IMG-007
Drug
Lead sponsor
Inmagene LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
11
States / cities
Rogers, Arkansas • Lomita, California • Tampa, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Phase 2 Interventional

Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI

NCT04232657
View directory record Official record
Conditions
Spinal Cord Injury (=3 Years), Sublesional Bone Loss Secondary to SCI
Interventions
Romosozumab, Denosumab, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
West Orange, New Jersey • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Not applicable Interventional

Peau o le Vasa: Analysis of the Efficacy and Feasibility of the PILI Lifestyle Program (PLP) + Social Determinants of Health (SDOH) Intervention and Adaptation of SDOH Measures Pilot Study

NCT06471595
View directory record Official record
Conditions
Weight Loss Trial, Cardiometabolic Syndrome, Hypertension, Dyslipidemia, Pre-diabetes, Type 2 Diabetes Mellitus
Interventions
Partnership for Improving Lifestyle Intervention (PILI) Lifestyle Program + Social Determinants of Health (SDOH) Component
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Fayetteville, Arkansas • Springdale, Arkansas • Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Not applicable Interventional

Hearing Health Care Service Access and Use

NCT02037139
View directory record Official record
Conditions
Hearing Loss
Interventions
Screening, Brochure, Education
Other · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Oct 20, 2026, 6:32 AM EDT
Completed Phase 3 Interventional Results available

Comparison of Liraglutide Versus Placebo in Weight Loss Maintenance in Obese Subjects: SCALE - Maintenance

NCT00781937
View directory record Official record
Conditions
Metabolism and Nutrition Disorder, Obesity
Interventions
liraglutide, placebo
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
27
States / cities
Goodyear, Arizona • Peoria, Arizona • Huntington Beach, California + 22 more
Source: ClinicalTrials.gov public record
Updated Nov 1, 2017 · Synced Oct 20, 2026, 6:32 AM EDT