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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:02 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 505–528 of 3,723 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Loss Clear all
Completed Phase 3 Interventional

Creatine in Treating Patients With Cancer-Associated Weight Loss

NCT00081250
View directory record Official record
Conditions
Anorexia, Cachexia, Unspecified Adult Solid Tumor, Protocol Specific, Weight Changes
Interventions
creatine monohydrate, placebo
Dietary Supplement · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2017
U.S. locations
220
States / cities
Mobile, Alabama • Scottsdale, Arizona • Aurora, Colorado + 139 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2020 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional

Hearing Health Care Service Access and Use

NCT02037139
View directory record Official record
Conditions
Hearing Loss
Interventions
Screening, Brochure, Education
Other · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multicenter Endoscopic Sleeve Gastrectomy (ESG) Trial (MERIT Trial)

NCT03406975
View directory record Official record
Conditions
Obesity, Hypertension, Diabetes Mellitus, Type 2
Interventions
Overstitch Endoscopic Suture System, Lifestyle Intervention
Device · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years to 65 Years
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
9
States / cities
Orlando, Florida • Chicago, Illinois • Evanston, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Almased Multi-Center Diabetes Intervention Trial

NCT01702012
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
Almased Meal Replacement Powder, Group-Based Lifestyle Intervention
Dietary Supplement · Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 31, 2020 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Results available

Prevention of Post Operative Bone Loss in Children

NCT00655681
View directory record Official record
Conditions
Osteoporosis, Cerebral Palsy, Spina Bifida, Osteopenia, Osteogenesis Imperfecta
Interventions
pamidronate, saline
Drug · Other
Lead sponsor
University of New Mexico
Other
Eligibility
4 Years to 18 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Oct 21, 2026, 4:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Wearable Photoplethysmography for Non-invasive Hydration Assessment

NCT07520344
View directory record Official record
Conditions
Hydration Status
Interventions
Exercise
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Frisco, Texas • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional

Behavioral CVD Prevention Using Informatics

NCT02752464
View directory record Official record
Conditions
Health Behavior
Interventions
Counseling, feedback report
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Oct 21, 2026, 4:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Increased Dietary Protein Intake During GLP-1 Medication Use (in Middle-aged Women With Overweight/Obesity)

NCT07480109
View directory record Official record
Conditions
Obesity, Women (Between 30 to 60 Years Old)
Interventions
Protein Rich Foods
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
30 Years to 60 Years · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Results available

Integrating Online Weight Management With Primary Care Support

NCT02656693
View directory record Official record
Conditions
Obesity
Interventions
Online weight management program, Population health management support
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years to 70 Years
Enrollment
840 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Oct 21, 2026, 4:02 AM EDT
Completed No phase listed Observational Results available

A US Study to Look at Loss of Work and Healthcare Costs for People Affected With Mild-to-moderate COVID 19 Who Have High Chances of the Disease Becoming Severe

NCT07072793
View directory record Official record
Conditions
COVID-19 (Coronavirus Disease 2019)
Interventions
nirmatrelvir-ritonavir
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
131,005 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Active, not recruiting Not applicable Interventional

Weight Loss Clinical Decision Support

NCT05198765
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
BMI-CDS
Behavioral
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
10,120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Results available

OA Clinic-Community CARE Model

NCT05349500
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Overweight, Obesity, Physical Inactivity, Weight Loss
Interventions
OA CARE Intervention, Usual Care control group
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional

Exploring Beliefs and Behaviors About Weight Loss in Couples

NCT01777711
View directory record Official record
Conditions
Obesity
Interventions
Mental Contrasting- Individual, Mental Contrasting- Couple
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 26, 2014 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Results available

Expanding the Family Check-Up in Early Childhood to Promote Cardiovascular Health of Mothers and Young Children

NCT05473767
View directory record Official record
Conditions
Obesity, Maternal, Hypertension in Pregnancy, Hypertension, Pregnancy-Induced, Diabetes, Overweight
Interventions
Family Check Up Heart, Family Check-Up
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
Not listed
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Phase 3 Interventional

Amblyopia (Lazy Eye) Treatment Study

NCT00001864
View directory record Official record
Conditions
Amblyopia, Anisometropia, Strabismus
Interventions
Atropine, Patch
Drug · Device
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional

Early Intervention and Prevention of Non-Alcoholic Fatty Liver Disease in Adolescents

NCT02116192
View directory record Official record
Conditions
Non-alcoholic Fatty Liver Disease
Interventions
Experimental: Low-fructose, reduced carbohydrate diet, General Healthy Diet
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
11 Years to 17 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 11, 2018 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance

NCT02380963
View directory record Official record
Conditions
Overweight, Obesity, Weight Loss
Interventions
Colorado Diet with soy protein foods., Colorado Diet with monetary payments
Dietary Supplement · Behavioral
Lead sponsor
DuPont Nutrition and Health
Industry
Eligibility
18 Years to 55 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 4, 2019 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Phase 1Phase 2 Interventional

Interpersonal Psychotherapy for Depression in People With Heart Failure

NCT00353223
View directory record Official record
Conditions
Depression, Heart Failure, Congestive
Interventions
Interpersonal and behavioral psychotherapy, Attention control (AC) condition
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
55 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 3, 2013 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Endoscopic Surgery for Bariatric Revision After Weight Loss Failure

NCT01871896
View directory record Official record
Conditions
Morbid Obesity, Weight Loss
Interventions
Endoscopic Suturing to Create Early Satiety
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2023 · Synced Oct 21, 2026, 4:02 AM EDT
Recruiting Not applicable Interventional

Brain Outcomes With Lifestyle Change in Down Syndrome

NCT05985486
View directory record Official record
Conditions
Down Syndrome, Alzheimer Disease, Obesity
Interventions
Diet, Health Education
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 64 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Progression of Gastroesophageal Reflux Disease and Barrett's Esophagus and the Creation of a Barrett's Registry

NCT00574327
View directory record Official record
Conditions
Barrett's Esophagus, Gastroesophageal Reflux Disease, Esophageal Adenocarcinoma
Interventions
Not listed
Lead sponsor
Midwest Biomedical Research
Other
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2029
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 16, 2023 · Synced Oct 21, 2026, 4:02 AM EDT
Completed No phase listed Observational

Multimodal Approach to Testing the Acute Effects of Mild Traumatic Brain Injury (mTBI)

NCT02069613
View directory record Official record
Conditions
Concussion, Mild
Interventions
Not listed
Lead sponsor
Huntington Medical Research Institutes
Other
Eligibility
18 Years to 50 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Nov 8, 2017 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PREPARE: A Randomized Trial of a Pre-pregnancy Weight Loss Intervention

NCT02346162
View directory record Official record
Conditions
Overweight, Obese
Interventions
Weight management, Usual Care Control
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
326 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Oct 21, 2026, 4:02 AM EDT
Completed No phase listed Observational

Study of Tissue and Blood Samples From Patients With Low-Grade Glioma

NCT01004523
View directory record Official record
Conditions
Brain and Central Nervous System Tumors
Interventions
fluorescence in situ hybridization, loss of heterozygosity analysis, polymerase chain reaction, flow cytometry, immunohistochemistry staining method
Genetic · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
Not listed
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2013
U.S. locations
38
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Clive, Iowa + 19 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2016 · Synced Oct 21, 2026, 4:02 AM EDT